Termination of Electron Acceleration in Thundercloud by Intra/Inter-cloud Discharge

An on-ground observation program for high energy atmospheric phenomena in winter thunderstorms along Japan Sea has been performed via measurements of gamma-ray radiation, atmospheric electric field and low-frequency radio band. On February 11, 2017, the radiation detectors recorded gamma-ray emission lasting for 75 sec. The gamma-ray spectrum extended up to 20 MeV and was reproduced by a cutoff power-law model with a photon index of $1.36^{+0.03}_{-0.04}$, being consistent with a Bremsstrahlung radiation from a thundercloud (as known as a gamma-ray glow and a thunderstorm ground enhancement). Then the gamma-ray glow was abruptly terminated with a nearby lightning discharge. The low-frequency radio monitors, installed $\sim$50 km away from the gamma-ray observation site recorded leader development of an intra/inter-cloud discharge spreading over $\sim$60 km area with a $\sim$300 ms duration. The timing of the gamma-ray termination coincided with the moment when the leader development of the intra/inter-cloud discharge passed 0.7 km horizontally away from the radiation monitors. The intra/inter-cloud discharge started $\sim$15 km away from the gamma-ray observation site. Therefore, the glow was terminated by the leader development, while it did not trigger the lightning discharge in the present case.Comment: 12 pages, 4 figures, accepted for publication in Geophysical Research Letter

Sistema por injeção seqüencial utilizando pervaporação na avaliação da eficiência de calagem em solos.

Nos solos minerais, existem uma relação entre os componentes da acidez; a medida que aumenta a disponibilidade de ca2+ e mg2 trocáveis, diminuem os teores de al 3+ troçável e de acidez. a aplicação do calcário faz com que essa relação ocorra, porém, a utilizado de doses excessivas, associada a sua má distribuição e má incorporação poderá resultar diminuição da disponibilidade de outros nutrientes, estimulo à ocorrência de doenças, etc.. a pervaporação analítica pode ser definida como a integração da evaporação com difusão gasosa em um único modulo. surgiu \tcomo alternativa viável a difusão gasosa, podendo ser utilizada para análise direta de amostras sólidas, uma vez que a amostra não entra em contato com a membrana de difusão. o objetivo principal deste trabalho foi o de acoplar a técnica de análise por injeção seqüencial (sia), o conceito da pervaporação, visando a determinação condutimétrica do teor de co2 liberado pelas amostras de cas

Citizen Science Observation of a Gamma‐Ray Glow Associated With the Initiation of a Lightning Flash

シチズンサイエンスで挑む雷の謎 --宇宙線と雷雲の相互作用は、雷の始まりに影響を与えるのか？--. 京都大学プレスリリース. 2023-07-10.Zeus also plays billiards: Citizen-supported Thundercloud Project may lead to better understanding of lightning's origins. 京都大学プレスリリース. 2023-07-12.Gamma-ray glows are observational evidence of relativistic electron acceleration due to the electric field in thunderclouds. However, it is yet to be understood whether such relativistic electrons contribute to the initiation of lightning discharges. To tackle this question, we started the citizen science “Thundercloud Project, ” where we map radiation measurements of glows from winter thunderclouds along Japan's sea coast area. We developed and deployed 58 compact gamma-ray monitors at the end of 2021. On 30 December 2021, five monitors simultaneously detected a glow with its radiation distribution horizontally extending for 2 km. The glow terminated coinciding with a lightning flash at 04:08:34 JST, which was recorded by the two radio-band lightning mapping systems, FALMA and DALMA. The initial discharges during the preliminary breakdown started above the glow, that is, in vicinity of the electron acceleration site. This result provides one example of possible connections between electron acceleration and lightning initiation

T Helper 1 (Th1) and Th2 Characteristics Start to Develop During T Cell Priming and Are Associated with an Immediate Ability to Induce Immunoglobulin Class Switching

The respective production of specific immunoglobulin (Ig)G2a or IgG1 within 5 d of primary immunization with Swiss type mouse mammary tumor virus [MMTV(SW)] or haptenated protein provides a model for the development of T helper 1 (Th1) and Th2 responses. The antibody-producing cells arise from cognate T cell B cell interaction, revealed by the respective induction of Cγ2a and Cγ1 switch transcript production, on the third day after immunization. T cell proliferation and upregulation of mRNA for interferon γ in response to MMTV(SW) and interleukin 4 in response to haptenated protein also starts during this day. It follows that there is minimal delay in these responses between T cell priming and the onset of cognate interaction between T and B cells leading to class switching and exponential growth. The Th1 or Th2 profile is at least partially established at the time of the first cognate T cell interaction with B cells in the T zone

Why Are Outcomes Different for Registry Patients Enrolled Prospectively and Retrospectively? Insights from the Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF).

Background: Retrospective and prospective observational studies are designed to reflect real-world evidence on clinical practice, but can yield conflicting results. The GARFIELD-AF Registry includes both methods of enrolment and allows analysis of differences in patient characteristics and outcomes that may result. Methods and Results: Patients with atrial fibrillation (AF) and ≥1 risk factor for stroke at diagnosis of AF were recruited either retrospectively (n = 5069) or prospectively (n = 5501) from 19 countries and then followed prospectively. The retrospectively enrolled cohort comprised patients with established AF (for a least 6, and up to 24 months before enrolment), who were identified retrospectively (and baseline and partial follow-up data were collected from the emedical records) and then followed prospectively between 0-18 months (such that the total time of follow-up was 24 months; data collection Dec-2009 and Oct-2010). In the prospectively enrolled cohort, patients with newly diagnosed AF (≤6 weeks after diagnosis) were recruited between Mar-2010 and Oct-2011 and were followed for 24 months after enrolment. Differences between the cohorts were observed in clinical characteristics, including type of AF, stroke prevention strategies, and event rates. More patients in the retrospectively identified cohort received vitamin K antagonists (62.1% vs. 53.2%) and fewer received non-vitamin K oral anticoagulants (1.8% vs . 4.2%). All-cause mortality rates per 100 person-years during the prospective follow-up (starting the first study visit up to 1 year) were significantly lower in the retrospective than prospectively identified cohort (3.04 [95% CI 2.51 to 3.67] vs . 4.05 [95% CI 3.53 to 4.63]; p = 0.016). Conclusions: Interpretations of data from registries that aim to evaluate the characteristics and outcomes of patients with AF must take account of differences in registry design and the impact of recall bias and survivorship bias that is incurred with retrospective enrolment. Clinical Trial Registration: - URL: http://www.clinicaltrials.gov . Unique identifier for GARFIELD-AF (NCT01090362)