346 research outputs found
‘If not with others, how?’: Creating Rabbinic Activists Through Study
Together we seek to model the redemptive, liberatory, activist, feminist approach to collaborative working to which both authors are committed as teachers, students, rabbis and activists. In our rabbinic chain of tradition (more particularly through other female rabbis) we explore, through the lenses of student and teacher, the 5-year rabbinic course at Leo Baeck College (LBC). We seek to demonstrate how, when working at its best, LBC trains rabbis as activists. Our contention is that the rabbinic education at LBC has the potential to be transformative in creating rabbis as activist leaders, an ideal which ought to transcend the rabbinic training seminary and be taken forward into community
First results of the SOAP project. Open access publishing in 2010
The SOAP (Study of Open Access Publishing) project has compiled data on the
present offer for open access publishing in online peer-reviewed journals.
Starting from the Directory of Open Access Journals, several sources of data
are considered, including inspection of journal web site and direct inquiries
within the publishing industry. Several results are derived and discussed,
together with their correlations: the number of open access journals and
articles; their subject area; the starting date of open access journals; the
size and business models of open access publishers; the licensing models; the
presence of an impact factor; the uptake of hybrid open access.Comment: Submitted to PLoS ON
Highlights from the SOAP project survey. What Scientists Think about Open Access Publishing
The SOAP (Study of Open Access Publishing) project has run a large-scale
survey of the attitudes of researchers on, and the experiences with, open
access publishing. Around forty thousands answers were collected across
disciplines and around the world, showing an overwhelming support for the idea
of open access, while highlighting funding and (perceived) quality as the main
barriers to publishing in open access journals. This article serves as an
introduction to the survey and presents this and other highlights from a
preliminary analysis of the survey responses. To allow a maximal re-use of the
information collected by this survey, the data are hereby released under a CC0
waiver, so to allow libraries, publishers, funding agencies and academics to
further analyse risks and opportunities, drivers and barriers, in the
transition to open access publishing.Comment: Data manual available at http://bit.ly/gI8nct Compressed CSV data
file available at http://bit.ly/gSmm71 Alternative data formats: CSV
http://bit.ly/ejuvKO XLS http://bit.ly/e6gE7o XLSX http://bit.ly/gTjyv
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Prenatal weight and regional body composition trajectories and neonatal body composition: The NICHD Foetal Growth Studies.
BackgroundGestational weight gain (GWG) and anthropometric trajectories may affect foetal programming and are potentially modifiable.ObjectivesTo assess concomitant patterns of change in weight, circumferences and adiposity across gestation as an integrated prenatal exposure, and determine how they relate to neonatal body composition.MethodsData are from a prospective cohort of singleton pregnancies (n = 2182) enrolled in United States perinatal centres, 2009-2013. Overall and by prepregnancy BMI group (overweight/obesity and healthy weight), joint latent trajectory models were fit with prenatal weight, mid-upper arm circumference (MUAC), triceps (TSF) and subscapular (SSF) skinfolds. Differences in neonatal body composition by trajectory class were assessed via weighted least squares.ResultsSix trajectory patterns reflecting co-occurring changes in weight and MUAC, SSF and TSF across pregnancy were identified overall and by body mass index (BMI) group. Among people with a healthy weight BMI, some differences were observed for neonatal subcutaneous adipose tissue, and among individuals with overweight/obesity some differences in neonatal lean mass were found. Neonatal adiposity measures were higher among infants born to individuals with prepregnancy overweight/obesity.ConclusionsSix integrated trajectory patterns of prenatal weight, subcutaneous adipose tissue and circumferences were observed that were minimally associated with neonatal body composition, suggesting a stronger influence of prepregnancy BMI
Asymptomatic giant coronary aneurysm in an adolescent with Behcet's syndrome
<p>Abstract</p> <p>Objective</p> <p>Behcet's is an idiopathic multi-organ syndrome, which may have onset during childhood. Vascular involvement is uncommon, with rarely reported coronary aneurysm formation. We present a case report of a teenager girl who developed recalcitrant life-threatening Behcet's vasculitis, involving both small and large venous and arterial systems including a giant coronary aneurysm.</p> <p>Case report</p> <p>De-identified data were collected retrospectively in case report format. Although our sixteen year old female with Behcet's vasculitis had resolution of many arterial aneurysms, she had persistent venous thrombosis of large vessels, as well as persistent, giant arterial aneurysms requiring intra-arterial coiling of a lumbar artery and coronary bypass grafting despite intensive immunosuppression including glucocorticoids, cyclophosphamide, infliximab, methotrexate, azathioprine and intravenous immunoglobulin.</p> <p>Conclusions</p> <p>Vascular manifestations may be seen in Behcet's syndrome, including asymptomatic coronary aneurysm, which may be refractory to immunosuppression and ultimately require surgical intervention. Increased awareness is essential for prompt diagnosis and management.</p
Impact of the COVID-19 Pandemic on the Welfare of Animals in Australia
We report on the various responses in Australia during 2020 to minimize negative impacts of the COVID-19 pandemic on the welfare of animals. Most organizations and individuals with animals under their care had emergency preparedness plans in place for various scenarios; however, the restrictions on human movement to contain the spread of COVID-19, coupled with the economic impact and the health effects of COVID-19 on the skilled workforce, constituted a new threat to animal welfare for which there was no blueprint. The spontaneous formation of a national, multisectoral response group on animal welfare, consisting of more than 34 organizations with animals under their care, facilitated information flow during the crisis, which helped to mitigate some of the shocks to different organizations and to ensure continuity of care for animals during the pandemic. We conclude that animal welfare is a shared responsibility, and accordingly, a multisectoral approach to animal welfare during a crisis is required. Our experience demonstrates that to safeguard animal welfare during crises, nations should consider the following: a national risk assessment, clear communication channels, contingency plans for animal welfare, a crisis response group, and support systems for animal care providers. Our findings and recommendations from the Australian context may inform other countries to ensure that animal welfare is not compromised during the course of unpredictable events
Early dissemination of bevacizumab for advanced colorectal cancer: a prospective cohort study
<p>Abstract</p> <p>Background</p> <p>We describe early dissemination patterns for first-line bevacizumab given for metastatic colorectal cancer treatment.</p> <p>Methods</p> <p>We analyzed patient surveys and medical records for a population-based cohort with metastatic colorectal cancer treated in multiple regions and health systems in the United States (US). Eligible patients were diagnosed with metastatic colorectal cancer and initiated first-line chemotherapy after US Food & Drug Administration (FDA) bevacizumab approval in February 2004. First-line bevacizumab therapy was defined as receiving bevacizumab within 8 weeks of starting chemotherapy for metastatic colorectal cancer. We evaluated factors associated with first-line bevacizumab treatment using logistic regression.</p> <p>Results</p> <p>Among 355 patients, 31% received first-line bevacizumab in the two years after FDA approval, including 26% of men, 41% of women, and 16% of those ≥ 75 years. Use rose sharply within 6 months after FDA approval, then plateaued. 20% of patients received bevacizumab in combination with irinotecan; 53% received it with oxaliplatin. Men were less likely than women to receive bevacizumab (adjusted OR 0.55; 95% CI 0.32-0.93; p = 0.026). Patients ≥ 75 years were less likely to receive bevacizumab than patients < 55 years (adjusted OR 0.13; 95% CI 0.04-0.46; p = 0.001).</p> <p>Conclusions</p> <p>One-third of eligible metastatic colorectal cancer patients received first-line bevacizumab shortly after FDA approval. Most patients did not receive bevacizumab as part of the regimen used in the pivotal study leading to FDA approval.</p
Objective burden, resources, and other stressors among informal cancer caregivers: a hidden quality issue?
A great deal of clinical cancer care is delivered in the home by informal caregivers (e.g. family, friends), who are often untrained. Caregivers' context varies widely, with many providing care despite low levels of resources and high levels of additional demands
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