331 research outputs found
âIf not with others, how?â: Creating Rabbinic Activists Through Study
Together we seek to model the redemptive, liberatory, activist, feminist approach to collaborative working to which both authors are committed as teachers, students, rabbis and activists. In our rabbinic chain of tradition (more particularly through other female rabbis) we explore, through the lenses of student and teacher, the 5-year rabbinic course at Leo Baeck College (LBC). We seek to demonstrate how, when working at its best, LBC trains rabbis as activists. Our contention is that the rabbinic education at LBC has the potential to be transformative in creating rabbis as activist leaders, an ideal which ought to transcend the rabbinic training seminary and be taken forward into community
First results of the SOAP project. Open access publishing in 2010
The SOAP (Study of Open Access Publishing) project has compiled data on the
present offer for open access publishing in online peer-reviewed journals.
Starting from the Directory of Open Access Journals, several sources of data
are considered, including inspection of journal web site and direct inquiries
within the publishing industry. Several results are derived and discussed,
together with their correlations: the number of open access journals and
articles; their subject area; the starting date of open access journals; the
size and business models of open access publishers; the licensing models; the
presence of an impact factor; the uptake of hybrid open access.Comment: Submitted to PLoS ON
Highlights from the SOAP project survey. What Scientists Think about Open Access Publishing
The SOAP (Study of Open Access Publishing) project has run a large-scale
survey of the attitudes of researchers on, and the experiences with, open
access publishing. Around forty thousands answers were collected across
disciplines and around the world, showing an overwhelming support for the idea
of open access, while highlighting funding and (perceived) quality as the main
barriers to publishing in open access journals. This article serves as an
introduction to the survey and presents this and other highlights from a
preliminary analysis of the survey responses. To allow a maximal re-use of the
information collected by this survey, the data are hereby released under a CC0
waiver, so to allow libraries, publishers, funding agencies and academics to
further analyse risks and opportunities, drivers and barriers, in the
transition to open access publishing.Comment: Data manual available at http://bit.ly/gI8nct Compressed CSV data
file available at http://bit.ly/gSmm71 Alternative data formats: CSV
http://bit.ly/ejuvKO XLS http://bit.ly/e6gE7o XLSX http://bit.ly/gTjyv
Asymptomatic giant coronary aneurysm in an adolescent with Behcet's syndrome
<p>Abstract</p> <p>Objective</p> <p>Behcet's is an idiopathic multi-organ syndrome, which may have onset during childhood. Vascular involvement is uncommon, with rarely reported coronary aneurysm formation. We present a case report of a teenager girl who developed recalcitrant life-threatening Behcet's vasculitis, involving both small and large venous and arterial systems including a giant coronary aneurysm.</p> <p>Case report</p> <p>De-identified data were collected retrospectively in case report format. Although our sixteen year old female with Behcet's vasculitis had resolution of many arterial aneurysms, she had persistent venous thrombosis of large vessels, as well as persistent, giant arterial aneurysms requiring intra-arterial coiling of a lumbar artery and coronary bypass grafting despite intensive immunosuppression including glucocorticoids, cyclophosphamide, infliximab, methotrexate, azathioprine and intravenous immunoglobulin.</p> <p>Conclusions</p> <p>Vascular manifestations may be seen in Behcet's syndrome, including asymptomatic coronary aneurysm, which may be refractory to immunosuppression and ultimately require surgical intervention. Increased awareness is essential for prompt diagnosis and management.</p
Early dissemination of bevacizumab for advanced colorectal cancer: a prospective cohort study
<p>Abstract</p> <p>Background</p> <p>We describe early dissemination patterns for first-line bevacizumab given for metastatic colorectal cancer treatment.</p> <p>Methods</p> <p>We analyzed patient surveys and medical records for a population-based cohort with metastatic colorectal cancer treated in multiple regions and health systems in the United States (US). Eligible patients were diagnosed with metastatic colorectal cancer and initiated first-line chemotherapy after US Food & Drug Administration (FDA) bevacizumab approval in February 2004. First-line bevacizumab therapy was defined as receiving bevacizumab within 8 weeks of starting chemotherapy for metastatic colorectal cancer. We evaluated factors associated with first-line bevacizumab treatment using logistic regression.</p> <p>Results</p> <p>Among 355 patients, 31% received first-line bevacizumab in the two years after FDA approval, including 26% of men, 41% of women, and 16% of those â„ 75 years. Use rose sharply within 6 months after FDA approval, then plateaued. 20% of patients received bevacizumab in combination with irinotecan; 53% received it with oxaliplatin. Men were less likely than women to receive bevacizumab (adjusted OR 0.55; 95% CI 0.32-0.93; p = 0.026). Patients â„ 75 years were less likely to receive bevacizumab than patients < 55 years (adjusted OR 0.13; 95% CI 0.04-0.46; p = 0.001).</p> <p>Conclusions</p> <p>One-third of eligible metastatic colorectal cancer patients received first-line bevacizumab shortly after FDA approval. Most patients did not receive bevacizumab as part of the regimen used in the pivotal study leading to FDA approval.</p
Objective burden, resources, and other stressors among informal cancer caregivers: a hidden quality issue?
A great deal of clinical cancer care is delivered in the home by informal caregivers (e.g. family, friends), who are often untrained. Caregivers' context varies widely, with many providing care despite low levels of resources and high levels of additional demands
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CloudSat and CALIPSO within the A-Train: ten years of actively observing the Earth system
One of the most successful demonstrations of an integrated approach to observe Earth from multiple perspectives is the A-Train satellite constellation (e.g. Stephens et al., 2002). The science enabled by this constellation flourished with the introduction of the two active sensors carried by the NASA CloudSat and the NASA/CNES Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO) satellites that were launched together on April 28th, 2006. These two missions have provided a 10-year demonstration of coordinated formation flying that made it possible to develop integrated products and that offered new insights on key atmospheric processes. The progress achieved over this decade of observations, summarized in this paper, clearly demonstrate the fundamental importance of the vertical structure of clouds and aerosol for understanding the influences of the larger scale atmospheric circulation on aerosol, the hydrological cycle, the cloud-scale physics and on the formation of the major storm systems of Earth. The research also underscored inherent ambiguities in radiance data in describing cloud properties and how these active systems have greatly enhanced passive observation. It is now clear that monitoring the vertical structure of clouds and aerosol is essential and a climate data record is now being constructed. These pioneering efforts are to be continued with EarthCARE mission planned for launch in 2019
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