The effectiveness of psychological interventions for post-traumatic stress disorder in children, adolescents and young adults: A systematic review and meta-analysis

Background: Children and adolescents display different symptoms of post-traumatic stress disorder (PTSD) than adults. Whilst evidence for the effectiveness of psychological interventions has been synthesised for adults, this is not directly applicable to younger people. Therefore, this systematic review and meta-analysis synthesised studies investigating the effectiveness of psychological interventions for PTSD in children, adolescents and young adults. It provides an update to previous reviews investigating interventions in children and adolescents, whilst investigating young adults for the first time. / Methods: We searched published and grey literature to obtain randomised control trials assessing psychological interventions for PTSD in young people published between 2011 and 2019. Quality of studies was assessed using the Cochrane Risk of Bias tool. Data were analysed using univariate random-effects meta-analysis. / Results: From 15 373 records, 27 met criteria for inclusion, and 16 were eligible for meta-analysis. There was a medium pooled effect size for all psychological interventions (d = −0.44, 95% CI −0.68 to −0.20), as well as for Trauma-Focused Cognitive Behavioural Therapy (TF-CBT) and Eye Movement Desensitisation and Reprocessing (EMDR) (d = −0.30, 95% CI −0.58 to −0.02); d = −0.46, 95% CI −0.81 to −0.12). / Conclusions: Some, but not all, psychological interventions commonly used to treat PTSD in adults were effective in children, adolescents and young adults. Interventions specifically adapted for younger people were also effective. Our results support the National Institute for Health and Care Excellence guidelines which suggest children and adolescents be offered TF-CBT as a first-line treatment because of a larger evidence base, despite EMDR being more effective

Anti-cancer efficiency of natural killer cells differentiated from human adipose tissue-derived mesenchymal stem cells and transfected with miRNA150

Aim: The aim of this study is to investigate the effects of miR150 transfection on NK-like cells differentiated from adipose tissue derived mesenchymal stem cells (AD-MSCs). Methods: NK-like cells were differentiated from AD-MSCs and activated by miR150 transfection. Transfected/non-transfected NK-like cells were characterized by immunohistochemical and RTPCR analyzes. Apoptotic efficiency of the transfected/non-transfected NK-like cells on pancreatic cancer cells PANC1 were determined by TUNEL and RT-PCR. Results: In miR150-transfected cells, the increased expression of NK cell-specific genes such as GZMB, KIR2DL2, CD16, CD56, NKG2D, NKp46 and increased immunoreactivity of NK cell-specific surface marker CD314 (NKG2D) were evident. TUNEL assays showed that NK-like cells with/without transfection induced apoptosis in PANC1 cells in the same manner. The decrease in oncogene expression and the increase in the tumor suppressor gene expression in PANC1 cells upon co-culture with NK-like cells differentiated from AD-MSCs were more prominent following miRNA150 transfection. Conclusion: It was shown in vitro that NK-like cells could be obtained by differentiation from AD-MSCs and their efficiency could be increased via miR150 transfection. The results are encouraging for further clinical studies in improvement of immunotherapeutic approaches for cancer therapy

A COMPARATIVE ANALYSIS OF THE FACTORS THAT INFLUENCE THE BRAND PREFERENCES OF UNIVERSITY STUDENTS STUDYING SPORTS IN TURKEY AND PORTUGAL

The purpose of this study is to find out and compare the factors effective in brand preferences of the students of Ondokuz Mayıs University Yaşar Doğu Faculty of Sport Sciences in Turkey and Instituto Politecnico da Guarda Faculty of Sports in Portugal in terms of sports products. 266 students (170 male, 96 female) attending sports faculties in Turkey and Portugal participated in this study. A questionnaire about the sports products preferences developed by Tozoğlu (2009) was used in order to find out the brand preferences of students. Student t-test was used to determine whether there is a significant difference between sport faculty students in Portugal and in Turkey. Chi square analysis was used to find out whether the students’ reasons for preferring a brand differed in terms of the schools, they were attending. Differences were found between the factors that affected the brand preferences of the students of Ondokuz Mayıs University (OMU) Yaşar Doğu Faculty of Sport Sciences and Instituto Politecnico da Guarda (IPG) Faculty of Sports in sports products. It was found that when compared with the students of IPG, students of OMU preferred brands since they provided quality guarantee, they were indicators of status and they gave a sense of security. It was found that students of OMU and IPG paid attention to the price while buying a brand product. Turkish students were found to be more dependent on brands when compared with Portuguese students. In addition, the price factor in the purchase of branded products is becoming a common element of the students of both countries. The tendency towards branded sporting products can manifest itself in increasing or decreasing proportions relative to advertising and promotional activities. The management of this orientation as a healthy process can be achieved by the effects of planned school education on the cultural structure.  Article visualizations

Land use and land cover mapping using deep learning based segmentation approaches and VHR Worldview-3 images

Deep learning-based segmentation of very high-resolution (VHR) satellite images is a significant task providing valuable information for various geospatial applications, specifically for land use/land cover (LULC) mapping. The segmentation task becomes more challenging with the increasing number and complexity of LULC classes. In this research, we generated a new benchmark dataset from VHR Worldview-3 images for twelve distinct LULC classes of two different geographical locations. We evaluated the performance of different segmentation architectures and encoders to find the best design to create highly accurate LULC maps. Our results showed that the DeepLabv3+ architecture with an ResNeXt50 encoder achieved the best performance for different metric values with an IoU of 89.46%, an F-1 score of 94.35%, a precision of 94.25%, and a recall of 94.49%. This design could be used by other researchers for LULC mapping of similar classes from different satellite images or for different geographical regions. Moreover, our benchmark dataset can be used as a reference for implementing new segmentation models via supervised, semi- or weakly-supervised deep learning models. In addition, our model results can be used for transfer learning and generalizability of different methodologies

Rethinking Service Systems and Public Policy: A Transformative Refugee Service Experience Framework

The global refugee crisis is a complex humanitarian problem. Service researchers can assist in solving this crisis because refugees are immersed in complex human service systems. Drawing on marketing, sociology, transformative service, and consumer research literature, this study develops a Transformative Refugee Service Experience Framework to enable researchers, service actors, and public policy makers to navigate the challenges faced throughout a refugee’s service journey. The primary dimensions of this framework encompass the spectrum from hostile to hospitable refugee service systems and the resulting suffering or well-being in refugees’ experiences. The authors conceptualize this at three refugee service journey phases (entry, transition, and exit) and at three refugee service system levels (macro, meso, and micro) of analysis. The framework is supported by brief examples from a range of service-related refugee contexts as well as a Web Appendix with additional cases. Moreover, the authors derive a comprehensive research agenda from the framework, with detailed research questions for public policy and (service) marketing researchers. Managerial directions are provided to increase awareness of refugee service problems; stimulate productive interactions; and improve collaboration among public and nonprofit organizations, private service providers, and refugees. Finally, this work provides a vision for creating hospitable refugee service systems

Intraperitoneal drain placement and outcomes after elective colorectal surgery: international matched, prospective, cohort study

Despite current guidelines, intraperitoneal drain placement after elective colorectal surgery remains widespread. Drains were not associated with earlier detection of intraperitoneal collections, but were associated with prolonged hospital stay and increased risk of surgical-site infections.Background Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery after surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed to describe international variation in intraperitoneal drain placement and the safety of this practice. Methods COMPASS (COMPlicAted intra-abdominal collectionS after colorectal Surgery) was a prospective, international, cohort study which enrolled consecutive adults undergoing elective colorectal surgery (February to March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included: rate and time to diagnosis of postoperative intraperitoneal collections; rate of surgical site infections (SSIs); time to discharge; and 30-day major postoperative complications (Clavien-Dindo grade at least III). After propensity score matching, multivariable logistic regression and Cox proportional hazards regression were used to estimate the independent association of the secondary outcomes with drain placement. Results Overall, 1805 patients from 22 countries were included (798 women, 44.2 per cent; median age 67.0 years). The drain insertion rate was 51.9 per cent (937 patients). After matching, drains were not associated with reduced rates (odds ratio (OR) 1.33, 95 per cent c.i. 0.79 to 2.23; P = 0.287) or earlier detection (hazard ratio (HR) 0.87, 0.33 to 2.31; P = 0.780) of collections. Although not associated with worse major postoperative complications (OR 1.09, 0.68 to 1.75; P = 0.709), drains were associated with delayed hospital discharge (HR 0.58, 0.52 to 0.66; P < 0.001) and an increased risk of SSIs (OR 2.47, 1.50 to 4.05; P < 0.001). Conclusion Intraperitoneal drain placement after elective colorectal surgery is not associated with earlier detection of postoperative collections, but prolongs hospital stay and increases SSI risk

A holistic framework of corporate website favourability

This paper extends the current knowledge of corporate website favourability (CWF) by developing a comprehensive conceptual model of its influence on corporate image, corporate reputation, loyalty and identification. The paper reviews previous studies on corporate websites from the perspectives of marketing, management, corporate identity and corporate visual identity in order to inform our understanding of the antecedents and consequences of CWF. The propositions and the conceptual framework present an approach by which a corporation can design and manage a favourable corporate website. A number of important contributions are offered: First, the paper adds to the understanding of CWF; second, it discusses the antecedents of CWF by drawing upon the existing literature; third, it is beneficial for practitioners in shaping CWF strategies, and fourth, it offers possible consequences of CWF and provides a framework for future testing

Does corporate reputation matter? Role of social media in consumer intention to purchase innovative food product

The exponential growth of the corporate reputation in food industry has resulted in innovations in every link of its supply chain. There have been studies that have characterized innovation in various industries from the perspective of technology, but far fewer in the area of corporate reputation, consumer perception, and intention towards innovations in food products. This research analyses the innovations in the food industry from the perspective of the consumer and provides a conceptual framework of food innovation stages. The study also investigates the relationship between corporate reputation and intention towards food innovation along with the other components of TPB model with an extension of social media engagement. The results from India and US samples confirm that social media engagement have a significant role to play in creating intention to purchase innovative food products. The study compares the US and Indian samples and identifies differences in subjective norms and perceived behavioural control

Geospatial mapping of a 16th century transport corridor for Southeast Europe

We need maximum slope values for carts and pack animals to model the historical traffic of people and goods before the advent of steam and internal combustion engines. With this article, we first calculate maximum slope averages for carts and pack animals by using an extensive geo-referenced and vectorized historical transport network for late 19th-century Southeast Europe. Then by utilizing these slopes and making joint use of the least-cost path, accumulated cost surfaces, and network analyses, we model the movement of carts and pack animals for a large segment of an Ottoman military campaign in 1532, which followed the Via Militaris, between Istanbul and Sofia. Lastly, we compare our modelled routes for carts and pack animals for the 16th century with the existing road infrastructure of the late 19th century