Frequency invariant beamforming for two-dimensional and three-dimensional arrays

A novel method for the design of two-dimensional (2-D) and three-dimensional (3-D)arrays with frequency invariant beam patterns is proposed. By suitable substitu- tions, the beam pattern of a 2-D or 3-D arrays can be regarded as the 3-D or 4-D Fourier transform of its spatial and temporal parameters. Since frequency invariance can be easily imposed in the Fourier domain, a simple design method is derived. Design examples for the 2-D case are provided

A user-centric system architecture for residential energy consumption reduction

Long-term energy consumption reduction can be achieved more readily through sensible cooperation between end users and technological advancements. The DANCER project presented here proposes a user-centric residential energy management system, with the intention to achieve long-term energy related behavioural changes, thus improving the energy efficiency of modern homes. Although, it follows the same basic principles as other contemporary approaches, it focuses on minimizing the interaction of the user with the system. This is achieved through an improved feedback mechanism and a generic, policy based service that takes advantage of the modularity and generality of the software architecture. The proposed system is designed to support a variety of technologies (WiFi, Zigbee, X10), in order to ameliorate the input and output of the decision making operation. In this paper, the general outline of the DANCER system architecture and its most important components are discussed and the prototype test-bed is presented. Special consideration is given to the implementation, operation and response behaviour of the prototype

Testing a Model of Minority Identity Achievement, Identity Affirmation and Psychological Well-Being among Ethnic Minority and Sexual Minority Individuals

How is social identity related to psychological well-being among minority individuals? Drawing on developmental models of identity formation (e.g., Erikson, 1968) and on Social Identity Theory (Tajfel & Turner, 1979), we tested a conceptual model examining links between two key aspects of social identity and psychological well-being. We proposed that the association between identity achievement (exploring and understanding the meaning of one\u27s identity) and psychological well-being is mediated by identity affirmation (developing positive feelings and a sense of belonging to one\u27s social group). Across three studies, including ethnic minority high school students (Study 1), ethnic minority college students (Study 2) and lesbian and gay male adults (Study 3), we found strong support for the model. Results suggest that the process of exploring and understanding one\u27s minority identity can serve as an important basis for developing positive feelings toward and an enhanced sense of attachment to the group, which can in turn confer psychological benefits for minority individuals. Implications and directions for future research are discussed

New onset left frontal lobe seizure presenting with ictal asystole

AbstractIctal asystole is a presumably rare but potentially fatal complication of seizures, most often of temporal lobe origin. It is believed that at least some cases of sudden unexplained death in epilepsy (SUDEP) might be triggered by ictal bradycardia or asystole. Current standard practice is to implant a permanent pacemaker in these patients to prevent syncope and/or death. However, emerging data suggests that effective medical or surgical treatment of epilepsy might be enough to prevent cardiac asystole, eliminating the need for permanent pacemaker placement. We describe a case of new onset left frontal lobe epilepsy in a young athletic patient who presented with near-syncopal episodes but whose comprehensive work-up revealed frequent events of ictal bradycardia and asystole. He responded well to monotherapy using oxcarbazepine, avoiding a permanent pacemaker

Discontinuous Phase Transition in an Exactly Solvable One-Dimensional Creation-Annihilation System

An exactly solvable reaction-diffusion model consisting of first-class particles in the presence of a single second-class particle is introduced on a one-dimensional lattice with periodic boundary condition. The number of first-class particles can be changed due to creation and annihilation reactions. It is shown that the system undergoes a discontinuous phase transition in contrast to the case where the density of the second-class particles is finite and the phase transition is continuous.Comment: Revised, 8 pages, 1 EPS figure. Accepted for publication in Journal of Statistical Mechanics: theory and experimen

De l’angine simple à l’abcès périamygdalien [From tonsillitis to peritonsillar abscess]

Acute tonsillitis is a common disease. The tonsillar infection can be uni- or bilateral with a high rate of spontaneous recovery. In some cases, a peritonsillar cellulitis or abscess can occur, characterized by an inflammatory reaction of the peritonsillar space. The red flags consist of a gradually worsening odynodysphagia, an ipsilateral swelling of the soft palate, a trismus (infrequent in children) and in some cases a change of voice (« hot potato voice »). A needle puncture of the swollen soft palate is then required. If pus is found, a surgical drainage by either hot tonsillectomy or incision under local anesthesia with an appropriate antibiotic therapy must be carried out

Mevalonate Cascade Regulation of Airway Mesenchymal Cell Autophagy and Apoptosis: A Dual Role for p53

Statins inhibit the proximal steps of cholesterol biosynthesis, and are linked to health benefits in various conditions, including cancer and lung disease. We have previously investigated apoptotic pathways triggered by statins in airway mesenchymal cells, and identified reduced prenylation of small GTPases as a primary effector mechanism leading to p53-mediated cell death. Here, we extend our studies of statin-induced cell death by assessing endpoints of both apoptosis and autophagy, and investigating their interplay and coincident regulation. Using primary cultured human airway smooth muscle (HASM) and human airway fibroblasts (HAF), autophagy, and autophagosome formation and flux were assessed by transmission electron microscopy, cytochemistry (lysosome number and co-localization with LC3) and immunoblotting (LC3 lipidation and Atg12-5 complex formation). Chemical inhibition of autophagy increased simvastatin-induced caspase activation and cell death. Similarly, Atg5 silencing with shRNA, thus preventing Atg5-12 complex formation, increased pro-apoptotic effects of simvastatin. Simvastatin concomitantly increased p53-dependent expression of p53 up-regulated modulator of apoptosis (PUMA), NOXA, and damage-regulated autophagy modulator (DRAM). Notably both mevalonate cascade inhibition-induced autophagy and apoptosis were p53 dependent: simvastatin increased nuclear p53 accumulation, and both cyclic pifithrin-α and p53 shRNAi partially inhibited NOXA, PUMA expression and caspase-3/7 cleavage (apoptosis) and DRAM expression, Atg5-12 complex formation, LC3 lipidation, and autophagosome formation (autophagy). Furthermore, the autophagy response is induced rapidly, significantly delaying apoptosis, suggesting the existence of a temporally coordinated p53 regulation network. These findings are relevant for the development of statin-based therapeutic approaches in obstructive airway disease

GHOST - safe-guarding home IoT environments with personalised real-time risk control

We present the European research project GHOST, (Safe-guarding home IoT environments with personalised real-time risk control), which challenges the traditional cyber security solutions for the IoT by proposing a novel reference architecture that is embedded in an adequately adapted smart home network gateway, and designed to be vendor-independent. GHOST proposes to lead a paradigm shift in consumer cyber security by coupling usable security with transparency and behavioural engineering

Genetic and molecular analysis of wheat tan spot resistance effective against Pyrenophora tritici-repentis races 2 and 5

Tan spot, a major foliar disease of wheat (Triticum aestivum L.), is caused by an ascomycete Pyrenophora tritici-repentis. Both culture filtrates and conidiospore inocula induce disease symptoms in susceptible wheat genotypes. The objectives of this study were to determine and map the genetic control of resistance to spore inocula and culture filtrates of P. tritici-repentis races 2 and 5. The F1 and F2 generations and an F2:6 recombinant inbred lines (RIL) population were developed from a cross between the resistant ND 735 and the susceptible Steele-ND. Disease assessments of the segregating generations were done at the seedling stage using culture filtrates and spore inocula under controlled environmental conditions. Genetic and mapping analyses of the F1 and F2 generations and the RIL by both methods indicated that the same single recessive gene, Tsr1, located on chromosome 5BL, controlled resistance and insensitivity to necrosis induced by race 2. A second recessive gene, designated Tsr6, located on chromosome 2BS, conferred resistance/insensitivity to chlorosis induced by spore inocula or culture filtrates of race 5. Diversity Arrays Technology markers wPt-3049 (2.9 cM) and wPt-0289 (4.6 cM) were closely linked to Tsr1 and Tsr6, respectively. The results further indicated that culture filtrates can be used as surrogates for spore inoculation. Tsr1 and Tsr6 can be selected by marker-assisted selection in breeding for resistance to tan spot

A mild alkali treated jute fibre controlling the hydration behaviour of greener cement paste

To reduce the antagonistic effect of jute fibre on the setting and hydration of jute reinforced cement, modified jute fibre reinforcement would be a unique approach. The present investigation deals with the effectiveness of mild alkali treated (0.5%) jute fibre on the setting and hydration behaviour of cement. Setting time measurement, hydration test and analytical characterizations of the hardened samples (viz., FTIR, XRD, DSC, TGA and free lime estimation) were used to evaluate the effect of alkali treated jute fibre. From the hydration test, the time (t) required to reach maximum temperature for the hydration of control cement sample is estimated to be 860 min, whilst the time (t) is measured to be 1040 min for the hydration of a raw jute reinforced cement sample. However, the time (t) is estimated to be 1020 min for the hydration of an alkali treated jute reinforced cement sample. Additionally, from the analytical characterizations, it is determined that fibre-cement compatibility is increased and hydration delaying effect is minimized by using alkali treated jute fibre as fibre reinforcement. Based on the analyses, a model has been proposed to explain the setting and hydration behaviour of alkali treated jute fibre reinforced cement composite