Why involve families in acute mental healthcare? A collaborative conceptual review

This article presents independent research funded by the National Institute for Health Research (NIHR), the East London NHS Foundation Trust and the Centre for Public Engagement (CPE) at Queen Mary University of London (QMUL). AD is funded by the NIHR Doctoral Research Fellowship (DRF-2015-08-071). DG was supported by the NIHR Collaboration for Leadership in Applied Health Research and Care (CLAHRC) North Thames at Barts Health NHS Trust. KB, GB and SC were supported by the Centre for Public Engagement at QMUL

Personality, posttraumatic stress and trauma type: factors contributing to posttraumatic growth and its domains in a Turkish community sample

Background: Posttraumatic growth (PTG) is conceptualized as a positive transformation resulting from coping with and processing traumatic life events. This study examined the contributory roles of personality traits, posttraumatic stress (PTS) severity and their interactions on PTG and its domains, as assessed with the Posttraumatic Growth Inventory Turkish form (PTGI-T). The study also examined the differences in PTG domains between survivors of accidents, natural disasters and unexpected loss of a loved one. Methods: The Basic Personality Traits Inventory, Posttraumatic Diagnostic Scale, and PTGI-T were administered to a large stratified cluster community sample of 969 Turkish adults in their home settings. Results: The results showed that conscientiousness, agreeableness, and openness to experience significantly related to the total PTG and most of the domains. The effects of extraversion, neuroticism and openness to experience were moderated by the PTS severity for some domains. PTG in relating to others and appreciation of life domains was lower for the bereaved group. Conclusion: Further research should examine the mediating role of coping between personality and PTG using a longitudinal design

Neotectonic evolution of the northwestward arched segment of the Central Anatolian Fault Zone, Central Anatolia, Turkey

Central Anatolia has undergone complex Neotectonic deformation since Late Miocene-Pliocene times. Many faults and intracontinental basins in this legion were either formed, or have been reactivated, during this period. The eastern part of central Anatolia is dominated by a NE-SW-trending, left lateral transcurrent structure named the Central Anatolian fault zone located between Sivas in the northeast and west of Mersin in the southwest. Around the central part, it is characterized by transtensional depressions formed by left stepping and southward bending of the fault zone. Pre-Upper Miocene basement rocks of the region consist of the central Anatolian crystalline complex and a sedimentary cover of Tertiary age. These rock units were strongly deformed by N-S convergence. The entire area emerged to become the site of erosion and formed a vast plateau before the Late Miocene. A NE-SW-trending extensional basin developed on this plateau in Late Miocene-Early Pliocene times. Rock units of this basin are characterized by a thick succession of pyroclastic rocks intercalated with calcalkaline-alkaline volcanics. The volcanic sequence is unconformably overlain by Pliocene lacustrine-fluviatile deposits intercalated with ignimbrites and tuffs. Thick, coarse grained alluvial/ colluvial fan deposits of marginal facies and fine grained clastics and carbonates of central facies display characteristic synsedimentary structures with volcanic intercalations. These are the main lines of evidence for development of a new transtensional Hirka-Kizilirmak basin in Pliocene times. Reactivation of the main segment of the Central Anatolian fault zone has triggered development of depressions around the left stepping and southward bending of the central part of this sinistral fault zone in the ignimbritic plateau during Late Pliocene-Quaternary time. These transtensional basins are named the Tuzla Golu and Sultansazligi pull-apart basins. The Sultansazligi basin has a lazy S to rhomboidal shape and displays characteristic morphologic features including a steep and stepped western margin, large alluvial and colluvial fans, and a huge composite volcano (the Erciyes Dagi)

GEOLOGICAL HISTORY OF THE NORTHWARD ARCHED SEGMENT OF THE NORTH ANATOLIAN TRANSFORM-FAULT ZONE

The study area is located in the southern part of the Central Pontides. The rocks exposed in this region have been divided into three major groups: basement, cover sequence and volcanic rocks. The basement rocks are composed of metamorphic units and a chaotic assemblage derived from an accretionary prism produced during the northward subduction of northern Neo-Tethys during the Late Cretaceous. During the same period, the basal element of the cover sequence, a thick and coarsening upward flysch succession (Cankurtaran Formation) was deposited in a tectonically active forearc regime. Towards the end of the Early Palaeocene, the entire study area emerged and became the site of erosion. During the Late Palaeocene to Early Eocene, the northern and southern parts of the study area were invaded by a new transgressing sea. This period was followed by uplift, volcanic activity and the formation of regressive sequences, events resulting from continental collision between the Anatolian and Pontide blocks during Late Eocene to Early Miocene times

I-convergence of positive linear operators on Lp weighted spaces

Demirci, Kamil/0000-0002-5976-9768WOS: 000253260900007In this paper, using the concept of I-convergence we prove a Korovkin type approximation by means of positive linear operators defined on the weighted space L-p,L-w(R). Also we state its n-dimensional analogue for the weighted space L-p,L-Omega(R-n). Also we display an example such that our method of convergence is stronger than the usual convergence in the weighted spaces L-p,L-w(R) and L-p,L-Omega(R-n)

Stratigraphy and pre-Miocene tectonic evolution of the southwestern part of the Sivas Basin, Central Anatolia, Turkey

In central Anatolia there are several important basins developed mainly after closure of the northern branch of Neotethys. These are the Haymana, Tuzgolu, Ulukisla, Kizihrmak, Cankiri-Corum and Sivas basins. The Sivas Basin is located in the eastern part of central Anatolia between the Central Anatolian Crystalline Complex (CACC) in the north and Taurides in the south. The basement to the southeastern part of the basin consists of recrystallized limestone and clastics of the Permian-Lower Cretaceous Bunyan Metamorphics. These units are overlain by an Upper Cretaceous ophiolitic olistostrome that is overthrust by ophiolites and high pressure-low temperature metamorphic rocks. Lower Palaeocene cover units unconformably overlie this sequence. The basement to the northwestern part is constituted by CACC that includes a high temperature-low pressure polymetamorphic succession of Palaeozoic-Mesozoic age, overthrust by ophiolites and intruded by Upper Cretaceous post-collisional granitoids and syenitoids. The uppermost Maastrichtian-Palaeocene continental to shallow marine (lagoonal) unit unconformably overlies this unit. Upper Cretaceous-Palaeocene siltstone, shale, pelagic limestone, volcaniclastic rocks and basic volcanic rock intercalations of a within-continental-plate eruptive setting have also been developed on the basement unit. These sequences represent the products of an extensional episode during Late. Cretaceous-Palaeocene times in the region between the Taurides and CACC. The Middle Eocene is represented by a regional transgression which was followed by a compressional episode evidenced by thrust faults at the margins and continued regression in the central part of the basin. This compressional period continued up to the end of the Early Miocene. Units formed during this episode are overlain by Upper Miocene-Quaternary continental units intercalated with volcanic rocks formed in fault-controlled extensional basins. It is suggested that the palaeotectonic events were the result of terminal closure of the northern branch of Neotethys. However, the neotectonic events are the result of the collision of the Arabian Plate and Anatolides which causes a westward escape of the Anatolian Plate. Copyright (C) 1999 John Wiley & Sons, Ltd

Dating the exhumation of a metamorphic dome: geological evidence for pre-Eocene unroofing of the Nigde Massif (Central Anatolia, Turkey)

The timing of exhumation of metamorphic rocks and granitoids of the Nigde metamorphic dome, at the southern tip of the Central Anatolian Crystalline Complex, is a matter of debate. According to some authors, the metamorphic rocks are overlain nonconformably by a sedimentary sequence of late Maastrichtian to Late Palaeocene age. In contrast, other authors recently argued that the Nigde dome represents an extensional core complex of Oligocene-Early Miocene age, finally unroofed during late Miocene times. On the one hand, the results Of Our study contradict the latter interpretation. A sedimentary sequence of earliest Eocene to early Middle Eocene age nonconformably overlies the high-grade rocks of the Nigde dome on its southeastern flank. Pebbles from the metamorphic rocks are ubiquitous in the conglomerates of this sequence. As a result, the Nigde metamorphic rocks must have reached the surface before Eocene times. or at the very beginning of the Eocene at the latest. The Uckapth granite, whose crystallization age has been inferred to be Early Miocene, has intruded the metamorphic complex during exhumation. The granite is also found as pebbles within the conglomerates of the Eocene sedimentary sequence and, thus, is actually older than the Eocene. Apatite fission track dates of 12-11 Ma across the Nigde dome do not indicate that the metamorphic rocks were still on their way to the surface at that time; instead, they must reflect a later event, which is most probably heating during late Neogene magmatism. Lastly, there is no ductile-then-brittle extensional detachment in the two areas where it has been invoked, that is, on the western and southern flanks of the dome. An extensional detachment nevertheless exists at the top of the Nidge dome, best documented in its northern part, where the detachment fault superposes a superficial unit made up of massive ophiolitic rocks onto the high-grade metamorphic sequence. Field evidence indicates that this detachment developed before Eocene times. Oil the other hand, our observations do not confirm the nonconformity of the sedimentary sequence dated as late Maastrichtian-Late Palaeocene onto the Nigde high-grade rocks. Field relations show either a tectonic contact between the two, or the direct nonconformity of the Eocene sediments onto the metamorphic rocks. The lack of coarse clasts originating from the Nigde high-grade rocks within the Maastrichtian-Palacocene sequence further suggests that the metamorphic dome did not reach the surface before Late Palaeocene times. These results compare well with available data from the northwestern part of the Central Anatolian Crystalline Complex, suggesting that exhumation has been broadly synchronous on the scale of the massif, as a result of an episode of high magnitude extension that affected the region in Campanian to Palaeocene times

Influences of human activities and agriculture on groundwater quality of Kayseri-Incesu-Dokuzpinar springs, central Anatolian part of Turkey

WOS: 000184074700012Human activities and agriculture have had direct and indirect effects on the rates of contamination of groundwater in the Incesu-Dokuzpinar spring area. Direct effects include dissolution and transport of excess quantities of fertilizers with associated materials and hydrological alterations related to irrigation and drainage. Indirect effects may include changes in water-rock reactions in soils and aquifers caused by increased concentrations of dissolved oxidants, protons, and major ions. Agricultural activities have directly or indirectly affected the concentrations of a large number of inorganic chemicals in groundwater, for example NO3, N-2, Cl, SO42, H+, K, Mg, Ca, Fe, Cu, B, Pb, and Zn, as well as a wide variety of pesticides and other organic compounds. For reactive contaminants like NO3, it is recommended that a combination of hydrochemical and environmental-tracer analytical approaches might be required to resolve changing inputs from subsequent alterations as causes of concentration gradients in groundwater. The water type of Dokuzpinar springs is mainly Na-Mg-Ca-Cl-HCO3. Note that the water types of the springs were directly related to the hydrogeochemical properties of outcrops at the study area. Thus, the high concentration of Ca2+ and HCO3 is mainly related to the high CO2 contents in the marbles, whereas the high Na concentration arises from the existing syenite, volcanic ash, basalt, and clay units, although the Incesu-Dokuzpinar springs cover most of the drinking and irrigation water demands of this area. The high concentrations of NO3 and NaCl show that the area around the springs is continuously being contaminated by untreated sewage and agricultural wastes, especially during dry periods. Therefore, this approach is based on the vulnerability studies of the catchment area, determination of the transfer time of the pollutant, and the water-bearing formations of Incesu-Dokuzpinar springs. Vulnerability in this study is defined as the intrinsic hydrogeochemical characteristics of an aquifer, which may show the sensitivity of groundwater to be contaminated by different human activities

Congenital Generalized Lipodystrophy, Type 4 (CGL4) Associated With Myopathy Due To Novel PTRF Mutations

Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive disorder characterized by near total absence of body fat since birth with predisposition to insulin resistance, diabetes, hypertriglyceridemia, and hepatic steatosis. Three CGL loci, AGPAT2, BSCL2, and CAV1, have been identified previously. Recently, mutations in polymerase I and transcript release factor (PTRF) were reported in five Japanese patients presenting with myopathy and CGL (CGL4). We report novel PTRF mutations and detailed phenotypes of two male and three female patients with CGL4 belonging to two pedigrees of Mexican origin (CGL7100 and CGL178) and one pedigree of Turkish origin (CGL180). All patients had near total loss of body fat and congenital myopathy manifesting as weakness, percussion-induced muscle mounding, and high serum creatine kinase levels. Four of them had hypertriglyceridemia. Three of them had atlantoaxial instability. Two patients belonging to CGL178 pedigree required surgery for pyloric stenosis in the first month of life. None of them had prolonged QT interval on electrocardiography but both siblings belonging to CGL7100 had exercise-induced ventricular arrhythmias. Three of them had mild acanthosis nigricans but had normal glucose tolerance. Two of them had hepatic steatosis. All patients had novel null mutations in PTRF gene. In conclusion, mutations in PTRF result in a novel phenotype that includes generalized lipodystrophy with mild metabolic derangements, myopathy, cardiac arrhythmias, atlantoaxial instability, and pyloric stenosis. It is unclear how mutations in PTRF, which plays an essential role in formation of caveolae, affect a wide variety of tissues resulting in a variable phenotype. (C) 2010 Wiley-Liss, Inc