Gestational Age Patterns of Fetal and Neonatal Mortality in Europe: Results from the Euro-Peristat Project

Background: The first European Perinatal Health Report showed wide variability between European countries in fetal (2.6– 9.1%) and neonatal (1.6–5.7%) mortality rates in 2004. We investigated gestational age patterns of fetal and neonatal mortality to improve our understanding of the differences between countries with low and high mortality. Methodology/Principal Findings: Data on 29 countries/regions participating in the Euro-Peristat project were analyzed. Most European countries had no limits for the registration of live births, but substantial variations in limits for registration of stillbirths before 28 weeks of gestation existed. Country rankings changed markedly after excluding deaths most likely to be affected by registration differences (22–23 weeks for neonatal mortality and 22–27 weeks for fetal mortality). Countries with high fetal mortality $28 weeks had on average higher proportions of fetal deaths at and near term ($37 weeks), while proportions of fetal deaths at earlier gestational ages (28–31 and 32–36 weeks) were higher in low fetal mortality countries. Countries with high neonatal mortality rates $24 weeks, all new member states of the European Union, had high gestational age-specific neonatal mortality rates for all gestational-age subgroups; they also had high fetal mortality, as well as high early and late neonatal mortality. In contrast, other countries with similar levels of neonatal mortality had varying levels of fetal mortality, and among these countries early and late neonatal mortality were negatively correlated. Conclusions: For valid European comparisons, all countries should register births and deaths from at least 22 weeks of gestation and should be able to distinguish late terminations of pregnancy from stillbirths. After excluding deaths most likely to be influenced by existing registration differences, important variations in both levels and patterns of fetal and neonatal mortality rates were found. These disparities raise questions for future research about the effectiveness of medical policies and care in European countries

Separability problem for multipartite states of rank at most four

One of the most important problems in quantum information is the separability problem, which asks whether a given quantum state is separable. We investigate multipartite states of rank at most four which are PPT (i.e., all their partial transposes are positive semidefinite). We show that any PPT state of rank two or three is separable and has length at most four. For separable states of rank four, we show that they have length at most six. It is six only for some qubit-qutrit or multiqubit states. It turns out that any PPT entangled state of rank four is necessarily supported on a 3x3 or a 2x2x2 subsystem. We obtain a very simple criterion for the separability problem of the PPT states of rank at most four: such a state is entangled if and only if its range contains no product vectors. This criterion can be easily applied since a four-dimensional subspace in the 3x3 or 2x2x2 system contains a product vector if and only if its Pluecker coordinates satisfy a homogeneous polynomial equation (the Chow form of the corresponding Segre variety). We have computed an explicit determinantal expression for the Chow form in the former case, while such expression was already known in the latter case.Comment: 19 page

Exile Vol. IV No. 1

The August Rose by Virginia Wallace 8-12 Beyond the Bauxite Mines by Barbara Ann Jucius 15-19 The Harvest by Anne Irgens 20-21 Recurrence: A Prose Poem by Nikos Stangos 22-27 The Day of the Painters by Edmund Boynton 28-35 Sophomore Slump by Jerilyn Robey 37-43 POETRY These Woods by Barbara Haupt 12 The Accused by Ellen Moore 13 Aberration by Barbara Haupt 19 Hate Eats by Karen Howey 21 Evanescence by Sandra Miskelly 36 Thoughts of You by William K. Lewis 36 Three Songs by Nikos Stangos 44 In this issue the editors of EXILE are proud to publish The Accused by Ellen Moore. This poem has been awarded the semi-annual Denison Book Store - EXILE Creative Writing Prize

Psychological and physical correlates of musculoskeletal symptoms in male professional divers and offshore workers

Background: Underwater divers are more likely to complain of musculoskeletal symptoms than a control population. Accordingly, we conducted a study to determine whether musculoskeletal symptoms reflected observable physical disorder, to ascertain the relationship between symptoms and measures of mood, memory and executive function and to assess any need for future screening. Methods: A 10% random sample of responders to a prior postal health questionnaire was examined (151 divers, 120 non-diving offshore workers). Participants underwent physical examination and a neuropsychological test battery for memory and executive function. Participants also completed the Hospital Anxiety and Depression Scale for anxiety (HADSa) and depression (HADSd), and questionnaires for physical health-related quality of life (SF36 PCS), mental health-related quality of life (SF36 MCS), memory (Cognitive Failures Questionnaire (CFQ), Prospective and Retrospective Memory Questionnaire (PRMQ)), executive function (dysexecutive syndrome questionnaire (DEX)), musculoskeletal symptoms (MSS) and general unrelated symptom reporting. Results: Of participants with moderate/severe musculoskeletal symptoms, 52% had physical signs, and of participants with no symptoms, 73% had no physical signs. There was no difference in the prevalence of signs or symptoms between groups. Musculoskeletal symptoms were associated with lower SF36 PCS for both groups. In divers, musculoskeletal symptoms were associated with higher general unrelated symptom reporting and poorer scoring for HADSa, PRMQ, CFQ and DEX with scores remaining within the normative range. A positive physical examination was associated with general unrelated symptom reporting in divers. There were no differences in neuropsychological test scores attributable to either group or musculoskeletal symptoms. Conclusions: Musculoskeletal symptoms were associated with physical signs, but this was not a strong effect. Reporting of musculoskeletal symptoms by the divers studied was also associated with a tendency to report symptoms generally or somatisation, and caution should be exercised regarding their interpretation as an indication of physical disease or their use for health screening

Weak lensing density profiles and mass reconstructions of the galaxy clusters Abell 1351 and Abell 1995

The aim of the present work is to study the overall mass distribution of the galaxy clusters Abell 1351 and Abell 1995 using weak gravitational lensing. These clusters have got a very different mass structure and dynamical state, and are the two extremes from a larger sample of 38 X-ray luminous clusters of similar size and redshift. We measure shear values of faint background galaxies and correct for PSF anisotropies using the KSB+ method. Two-dimensional mass maps of the clusters are created using a finite-field mass reconstruction algorithm, and verified with aperture mass statistics. The masses inferred from the reconstructions are compared to those obtained from fitting spherically symmetric SIS- and NFW-models to the tangential shear profiles. We discuss the NFW concentration parameters in detail. From the mass reconstructions we infer M200-masses of 11.7 +/- 3.1 * 10^14 h_70^-1 Msun and 10.5 +/- 2.7 * 10^14 h_70^-1 Msun for Abell 1351 and Abell 1995, respectively. About 3' north-east of the main mass peak of Abell 1351 we detect a significant secondary peak in the mass reconstruction as well as by aperture mass statistics. This feature is also traced by clusters members selected by means of their V-I colour, and hence is likely a real sub-structure of Abell 1351. From our fits to the tangential shear we infer masses on the order of M200 ~ 8-9 * 10^14 h_70^-1 Msun (Abell 1351) and M200 ~ 5-6 * 10^14 h_70^-1 Msun (Abell 1995). The concentration parameters remain poorly constrained by our weak lensing analysis.Comment: 16 pages, 7 figures, Accepted for publication in A&

Birth weight and melanoma risk: a population-based case–control study

We investigated whether lower birth weight was associated with lower risk of melanoma later in life. This population-based case–control study included all incident cases of histologically verified invasive melanoma diagnosed until 31 December 2003 in the Norwegian population born between 1967 and 1986 (n=709). The control group without malignant disease was established by random sampling from the same source population as the cases (n=108 209). Data on birth weight, gender, mother's residence and parental age at the time of birth were collected from the Medical Birth Registry of Norway and data on cancer from the Cancer Registry of Norway. The Mantel–Haenszel test of linear trend showed no trend in risk across the birth weight categories: individuals in the highest quartile of birth weight (⩾3860 g) had an odds ratio (OR) of 1.19 (95% confidence interval, CI: 0.77–1.84) compared to individuals with birth weight <2500 g. The adjusted OR was 0.81 (95% CI: 0.52–1.26) for birth weight below 2500 g (exposed). Though not statistically significant, the results suggest that low birth weight might influence the risk of melanoma later in life

Reference population for international comparisons and time trend surveillance of preterm delivery proportions in three countries

<p>Abstract</p> <p>Background</p> <p>International comparison and time trend surveillance of preterm delivery rates is complex. New techniques that could facilitate interpretation of such rates are needed.</p> <p>Methods</p> <p>We studied all live births and stillbirths (≥ 28 weeks gestation) registered in the medical birth registers in Sweden, Denmark and Norway from 1995 through 2004. Gestational age was determined by best estimate. A reference population of pregnant women was designed using the following criteria: 1) maternal age 20–35, 2) primiparity, 3) spontaneously conceived pregnancy, 4) singleton pregnancy and 5) mother born in the respective country. National preterm delivery rate, preterm delivery rate in the reference population and rate of spontaneous preterm delivery in the reference population were calculated for each country.</p> <p>Results</p> <p>The total national preterm delivery rate (< 37 completed gestational weeks), increased in both Denmark (5.3% to 6.1%, p < 0.001) and Norway (6.0% to 6.4%, p = 0.006), but remained unchanged in Sweden, during 1995–2004. In Denmark, the preterm delivery rate in the reference population (5.3% to 6.3%, p < 0.001) and the spontaneous preterm delivery rate in the reference population (4.4% to 6.8%, p < 0.001) increased significantly. No similar increase was evident in Norway. In Sweden, rates in the reference population remained stable.</p> <p>Conclusion</p> <p>Reference populations can facilitate overview and thereby explanations for changing preterm delivery rates. The model also permits comparisons over time. This model may in its simplicity prove to be a valuable supplement to assessments of national preterm delivery rates for public health surveillance.</p

Gravitational Lensing

Gravitational lensing has developed into one of the most powerful tools for the analysis of the dark universe. This review summarises the theory of gravitational lensing, its main current applications and representative results achieved so far. It has two parts. In the first, starting from the equation of geodesic deviation, the equations of thin and extended gravitational lensing are derived. In the second, gravitational lensing by stars and planets, galaxies, galaxy clusters and large-scale structures is discussed and summarised.Comment: Invited review article to appear in Classical and Quantum Gravity, 85 pages, 15 figure

Cluster Lenses

Clusters of galaxies are the most recently assembled, massive, bound structures in the Universe. As predicted by General Relativity, given their masses, clusters strongly deform space-time in their vicinity. Clusters act as some of the most powerful gravitational lenses in the Universe. Light rays traversing through clusters from distant sources are hence deflected, and the resulting images of these distant objects therefore appear distorted and magnified. Lensing by clusters occurs in two regimes, each with unique observational signatures. The strong lensing regime is characterized by effects readily seen by eye, namely, the production of giant arcs, multiple-images, and arclets. The weak lensing regime is characterized by small deformations in the shapes of background galaxies only detectable statistically. Cluster lenses have been exploited successfully to address several important current questions in cosmology: (i) the study of the lens(es) - understanding cluster mass distributions and issues pertaining to cluster formation and evolution, as well as constraining the nature of dark matter; (ii) the study of the lensed objects - probing the properties of the background lensed galaxy population - which is statistically at higher redshifts and of lower intrinsic luminosity thus enabling the probing of galaxy formation at the earliest times right up to the Dark Ages; and (iii) the study of the geometry of the Universe - as the strength of lensing depends on the ratios of angular diameter distances between the lens, source and observer, lens deflections are sensitive to the value of cosmological parameters and offer a powerful geometric tool to probe Dark Energy. In this review, we present the basics of cluster lensing and provide a current status report of the field.Comment: About 120 pages - Published in Open Access at: http://www.springerlink.com/content/j183018170485723/ . arXiv admin note: text overlap with arXiv:astro-ph/0504478 and arXiv:1003.3674 by other author