The early import of white marbles in Tarraco

En este trabajo se examinan en su conjunto las piezas arqueológicas en mármoles importados másantiguas de Tarraco, con el objetivo de conocer las circunstancias y las motivaciones del inicio delfenómeno de la importación de materiales lapídeos foráneos. Para ello, se reflexiona sobre aspectoscomo los talleres que elaboraron estos elementos, sus contextos topográficos y su funcionalidad.También se retoman cuestiones relacionadas con los problemas de datación que han planteado casitodas las inscripciones y esculturas consideradas. Como resultado, queda demostrado con claridad elpapel pionero de esta ciudad, en el contexto de Hispania, para la introducción de rocas ornamentalesextrapeninsulares.This paper presents the results of a study based on the earliest archaeological elements from Tarracomade on white marbles. The aim is to know the circumstances and motivations surrounding thephenome of importation of marble. Special attention has been paid to the workshops where theseelements were produced, as well as their original contexts and functionality. It will also discuss issuesrelated to chronological problems of the inscriptions and sculptures that were examined in this work.The results show that our city was a pioneer centre in the importation of foreign stones

Aneurisma del tronco principal de la arteria coronaria izquierda Descripción de un caso clínico y revisión de tema

El aneurisma arterial coronario constituye una entidad rara en la población; su incidencia varía entre 1,5% y 5%, siendo más frecuente en hombres. Existe escasa bibliografía acerca de esta patología a pesar de que su estudio se remonta a finales del siglo XVIII. La arteria que se afecta con mayor frecuencia es la coronaria derecha, aproximadamente en 40% de los casos. La dificultad al momento del diagnóstico clínico radica en que inicialmente el enfoque está dirigido a confirmar y tratar de manera oportuna el síndrome coronario agudo que con insistencia constituye la manifestación inicial con que cursan este tipo de pacientes; por ello el diagnóstico necesariamente requiere ayudas imaginológicas e intervencionistas, o ambas. Hay muchas causas que puedan producir aneurismas en la circulación coronaria, la más común de ellas es la aterosclerosisseguida por trastornos congénitos, enfermedades del tejido conectivo, vasculitis y consumo de cocaína entre otros. Recientemente se han publicado innovadores estudios respecto a la fisiopatología y los avances en terapéutica farmacológica e intervencionista, aunque el tratamiento debe enfocarse en los factores de riesgo, las patologías y las manifestaciones clínicas que presente el paciente.Coronary artery aneurysm is a rare entity in the population. Its incidence rates vary between 1.5% - 5%, and is more frequent in males. There is limited literature on this disease, although its study goes back to the late eighteenth century. The most frequently affected artery is the right coronary artery, in approximately 40% of cases. The initial diagnostic difficulty lies in the fact that the initial approach is focused in confirming and treating properly the coronary acute syndrome, which is the most frequent initial presentation in these patients. Therefore, its diagnosis requires necessarily imaging or interventionist aid, or both. Many causes account for coronary aneurysms, being the most common atherosclerosis followed by congenital abnormalities, connective tissue diseases, vasculitis and cocaine consumption. Novel studies regarding the physiopathology and advances in pharmacological and interventionist therapy have been published, although treatment must focus on risk factors, associated pathologies and clinical manifestations

Updating freeTribe to Support Efficient Synchronous Awareness in the Web Context

Abstract: The research field of Computer-Supported Cooperative Work has been reflected fundamentally in theoretical contributions. This contributions have constitute the base to carry out several intents to facilitate the work of the collaborative systems developers, however, current tool-kits, APIs or class libraries only eliminate partially the gap between the technical aspects that impose the information technology and the stressed social character of the process of collaboration in the World Wide Web. In this paper is presented the framework freeTribe, which involve the domain of the distributed groupwares leaning on the Cooperative Model of the methodology AMENITIES, in the middleware platform ICE and in RIA technologies; freeTribe has been designed as a software framework, to maximize its reusability and adaptability with a minimal programming effort. Support for synchronous group tasks in the Web context is increasingly recognized as a desideratum for collaborative systems and several tools have emerged recently that help groups of people with the same goals to work together, but many issues for these collaborative systems remain under studied. We identified synchronous awareness as one of these issues in collaborative systems, and updated freeTribe with four well-accepted kinds of awareness (group awareness, workspace awareness, contextual awareness, and peripheral awareness) by the community focusing our interest in its synchronous mechanism for efficient interaction in Web contexts.Keywords: computer-supported cooperative work, groupware, synchronous awareness.

Local and imported stones used on the official epigraphic programs of Tarraco until the Julio-Claudian period

En este trabajo se presentan los resultados del análisis macroscópico de las inscripciones en su día erigidas en espacios públicos de Tarraco, tomando en consideración el período comprendido entre finales de la República y la época julio-claudia. En total han sido recogidos 35 epígrafes. Los resultados, en combinación con la información arqueológica, permiten observar una notable heterogeneidad en los materiales lapídeos empleados, en contraposición a períodos posteriores en los que se impone la uniformidad. Asimismo, se ponen de relieve diferencias significativas en la elección del material, en función de la destinación y los usuarios de los soportes epigráficos. En paralelo, se discuten los aspectos relativos al contexto topográfico, la lectura e interpretación de los textos y la datación de cada una de las inscripciones.This paper presents the results of macroscopic analysis of the inscriptions from public spaces of Tarraco. It has taken into account the period between the Late Republic and the Julio-Claudian period. A total of 35 epigraphic monuments have been considered. Combined with the archaeological information, the results allow detecting a remarkable heterogeneity of stone materials, in contrast to later periods in which uniformity is imposed. Also, there are highlight significant differences in the choice of material, depending on the destination and users of the epigraphic supports. Furthermore, questions relating to the topographical context, reading and interpretation of texts and dating of the inscriptions are debated

Eficacia del diclofenaco tópico vs. nepafenaco tópico en la reducción del dolor durante la fotocoagulación panretiniana

ResumenPropósitoComparar la eficacia del diclofenaco tópico 0.1% vs. nepafenaco tópico en reducir el dolor asociado a la fotocoagulación panretiniana con láser argón.Material y métodosEnsayo clínico aleatorizado doble enmascarado, 132 pacientes (183 ojos) con diagnóstico de retinopatía diabética proliferativa tratados con fotocoagulación panretiniana. Aleatorización en 2 grupos: diclofenaco y nepafenaco tópicos. Se aplicaron 2 dosis de los analgésicos tópicos previas a la fotocoagulación panretiniana, se evaluó el dolor inmediatamente y 15min después. Se analizó nivel de dolor, efectos adversos y síntomas asociados al finalizar la fotocoagulación retiniana.ResultadosLa mediana de la edad para ambos grupos fue de 55 años, relación H:M de 1:1.4. El nivel de dolor inmediato fue de 35.5 (RIC 14-72) para el nepafenaco y de 45 (RIC 14-70) para el diclofenaco (p=0.48). A los 15min fue de 30 (RIC 4-50) para el nepafenaco y de 20 (RIC 2-50) para el diclofenaco (p=0.48). No hubo diferencias significativas en síntomas asociados entre los grupos ni efectos adversos en la superficie ocular.ConclusionesEl tratamiento previo con nepafenaco y diclofenaco tópicos es igualmente eficaz y seguro para reducir el dolor asociado a la fotocoagulación panretiniana en pacientes con retinopatía diabética proliferativa.AbstractPurposeTo compare the efficacy of topical diclofenac 0.1% vs topical nepafenac in reducing pain associated to argon laser retinal photocoagulationMaterial and methodsDouble blinded, randomized clinical trial. One hundred thirty two patients with diagnosis of proliferative diabetic retinopathy treated with retinal photocoagulation. Randomization in to 2 groups: topical diclofenac and nepafenac. Before retinal photocoagulation 2 doses of topical non-steroidal anti-inflammatory drugs were applied, pain was assessed immediately and 15minutes after. Level of pain, adverse effects and associated symptoms at the end of retinal photocoagulation were analyzed.ResultsThe median for age in both groups was 55 years, M:F ratio of 1:1.4. The immediate level of pain was 35.5 (ICR 14-72) for nepafenac and 45 (ICR 14-70) for diclofenac (P=.48). At 15minutes the pain level was 30 (ICR 4-50) for nepafenac and 20 (ICR 2-50) for diclofenac. There was no difference in associated symptoms or adverse effects among groups.ConclusionsThe preventive treatment with topical nepafenac and diclofenac is equally effective and safe for reducing the pain associated with retinal photocoagulation in patients with proliferative diabetic retinopathy

Hybrid parallel multimethod hyperheuristic for mixed-integer dynamic optimization problems in computational systems biology

[Abstract] This paper describes and assesses a parallel multimethod hyperheuristic for the solution of complex global optimization problems. In a multimethod hyperheuristic, different metaheuristics cooperate to outperform the results obtained by any of them isolated. The results obtained show that the cooperation of individual parallel searches modifies the systemic properties of the hyperheuristic, achieving significant performance improvements versus the sequential and the non-cooperative parallel solutions. Here we present and evaluate a hybrid parallel scheme of the multimethod, using both message-passing (MPI) and shared memory (OpenMP) models. The hybrid parallelization allows to achieve a better trade-off between performance and computational resources, through a compromise between diversity (number of islands) and intensity (number of threads per island). For the performance evaluation, we considered the general problem of reverse engineering nonlinear dynamic models in systems biology, which yields very large mixed-integer dynamic optimization problems. In particular, three very challenging problems from the domain of dynamic modeling of cell signaling were used as case studies. In addition, experiments have been carried out in a local cluster, a large supercomputer and a public cloud, to show the suitability of the proposed solution in different execution platforms.Gobierno de España; DPI2017-82896-C2-2-RGobierno de España; TIN2016-75845-PXunta de Galicia; R2016/045Xunta de Galicia; ED431C 2017/0

El uso del mármol Lunense en la epigrafía de ámbito público. El caso de Tarraco en época altoimperial (siglos I y III N.E)

El objetivo de este trabajo es presentar una panorámica del empleo del mármol lunense en la epigrafía monumental pública de Tarraco y su estrecha relación con el paisaje monumental urbano. Para ello se ofrece un catálogo actualizado de las inscripciones, contextualizadas arqueológicamente en los diversos enclaves de ámbito público implicados. Los resultados han permitido, por un lado, una definición más precisa del paisaje epigráfico urbano de la ciudad durante el Alto Imperio y, por otro, un mayor conocimiento sobre el empleo de este material tan significativo en la monumentalización de los espacios públicos, especialmente en el ámbito de una capital provincial.An overview is presented on the use of Carrara marble in monumental public inscriptions of Tarraco and its closed relations with the monumental urban landscape. Therefore, it is offered an updated catalog of inscriptions, related to some public areas in this Roman city. The results allow a more precise definition of the epigraphic urban landscape of the city during the first and second centuries AD. On the other hand, a better understanding on the diffusion of this stone material in the monumentalization of public spaces –especially in the context of a provincial capital– is drawn

Richness and Current Status of Gymnosperm Communities in Aguascalientes, Mexico

The gymnosperm diversity of Aguascalientes, Mexico, is presented. Fifteen species from five genera and three families are reported, two of Coniferales (Cupressaceae and Pinaceae) and one of Gnetales (Ephedraceae). Pinus is the most diverse and abundant genus with seven species. The most abundant species is P. teocote, while P. strobiformis is the scarcest. Juniperus is the next most diverse genus, represented by four species, with J. deppeana the most abundant and J. durangensis the scarcest. Cupressus lusitanica, Taxodium mucronatum and Ephedra compacta are each the sole representatives of their genera. Most conifers occupy the mountainous part of the state, forming temperate forest; exceptions are Taxodium, which is located on the margins of permanent streams, and J. coahuilensis, which is found in the low parts of the Aguascalientes Valley over calcareous soils in the northern part of the state. Ephedra is distributed in the northeast part of Aguascalientes in microphyll desert scrub. The current status of the gymnosperm communities in the state of Aguascalientes is discussed