375 research outputs found

    HB1010, Texas Education Codes 21.557 and 11.205 as Predictors of the Student at Risk of Dropping Out of School

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    Dropping out of school prior to the completion of requirements has become a nationwide problem of growing dimensions. The state legislature of Texas, not unlike legislatures in many other states, has charged educational professionals with overcoming or 7 at least diminishing the present startling dropout rate. Through House Bill 1010, criterion have been assigned for the identification of the student who is at risk of dropping out of school. In this study 169 tenth grade dropouts were used to test the mandatory and optional criteria established by the legislature for identifying these students, as well as criteria most indicated by the literature reviewed

    A review of the literature on stress and the school administrator

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    One of the most common maladies facing American society today is that of stress and its concomitant physiological and psychological effects. Too often it is actually the work environment that fosters a great deal of this tension and anxiety. Researchers estimate that half of all working people are unhappy with their careers, and that as many as 90 percent may be spending much of their time and energy at jobs that do not help them get any closer to their \u27goals in life\u27 (Hunt, 1983, p. 38)

    Songs Not Silenced: Music Forbidden in the Holocaust

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    Kennesaw State University School of Music presents this special performance, Songs Not Silenced: Music Forbidden in the Holocaust, featuring Jana Young, soprano, Oral Moses, bass-baritone, Judy Cole, piano, and commentary by program coordinator Dr. Laurence Sherr along with David Green.https://digitalcommons.kennesaw.edu/musicprograms/1900/thumbnail.jp

    Exploring the archive: live projects in a postgraduate learning setting

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    This case study outlines the pedagogic, curatorial and museological practices that have influenced a long-term collaboration between the Central Saint Martins Museum and Study Collection and the MA Culture, Criticism and Curation course, which have led to the inclusion of a formally assessed Archive and Curatorial unit in the MA’s curriculum. The study draws on concepts such as experiential learning, object-based or object-centred learning and collaborative meaning-making. It summarises the practicalities of enabling students to work with uncatalogued archive material and addresses the complexities of formulating curatorial narratives from multiple perspectives. It also explores the criticality required to surface tacit knowledge and engage with curatorial practices

    Extreme Dysbiosis of the Microbiome in Critical Illness.

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    Critical illness is hypothesized to associate with loss of "health-promoting" commensal microbes and overgrowth of pathogenic bacteria (dysbiosis). This dysbiosis is believed to increase susceptibility to nosocomial infections, sepsis, and organ failure. A trial with prospective monitoring of the intensive care unit (ICU) patient microbiome using culture-independent techniques to confirm and characterize this dysbiosis is thus urgently needed. Characterizing ICU patient microbiome changes may provide first steps toward the development of diagnostic and therapeutic interventions using microbiome signatures. To characterize the ICU patient microbiome, we collected fecal, oral, and skin samples from 115 mixed ICU patients across four centers in the United States and Canada. Samples were collected at two time points: within 48 h of ICU admission, and at ICU discharge or on ICU day 10. Sample collection and processing were performed according to Earth Microbiome Project protocols. We applied SourceTracker to assess the source composition of ICU patient samples by using Qiita, including samples from the American Gut Project (AGP), mammalian corpse decomposition samples, childhood (Global Gut study), and house surfaces. Our results demonstrate that critical illness leads to significant and rapid dysbiosis. Many taxons significantly depleted from ICU patients versus AGP healthy controls are key "health-promoting" organisms, and overgrowth of known pathogens was frequent. Source compositions of ICU patient samples are largely uncharacteristic of the expected community type. Between time points and within a patient, the source composition changed dramatically. Our initial results show great promise for microbiome signatures as diagnostic markers and guides to therapeutic interventions in the ICU to repopulate the normal, "health-promoting" microbiome and thereby improve patient outcomes. IMPORTANCE Critical illness may be associated with the loss of normal, "health promoting" bacteria, allowing overgrowth of disease-promoting pathogenic bacteria (dysbiosis), which, in turn, makes patients susceptible to hospital-acquired infections, sepsis, and organ failure. This has significant world health implications, because sepsis is becoming a leading cause of death worldwide, and hospital-acquired infections contribute to significant illness and increased costs. Thus, a trial that monitors the ICU patient microbiome to confirm and characterize this hypothesis is urgently needed. Our study analyzed the microbiomes of 115 critically ill subjects and demonstrated rapid dysbiosis from unexpected environmental sources after ICU admission. These data may provide the first steps toward defining targeted therapies that correct potentially "illness-promoting" dysbiosis with probiotics or with targeted, multimicrobe synthetic "stool pills" that restore a healthy microbiome in the ICU setting to improve patient outcomes

    Towards a more inclusive human resource community:Engaging ethnic minority microbusinesses in human resource development programmes targeted at more productive methods of operating

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    The economic and social importance of ethnic minority microbusinesses (‘EMMBs’ with 1–9 employees) is neglected in human resource (HR) academic and policy discourse on productive ways of working. This article presents an action research approach to show how academics and intermediaries (local trusted industry representatives) can collaborate to promote HR development programmes targeted at more productive methods of operating in EMMBs. Our research collaboration involves academics, EMMBs (from the catering and creative sectors) and intermediaries. We develop perspectives on HR in small firms by showing how EMMBs can be engaged in initiatives of learning and development targeted at organisational change. The study contributes to recent calls for a more inclusive approach to HR theorising and practice

    Functional connectivity network between terrestrial and aquatic habitats by a generalist waterbird, and implications for biovectoring

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    Birds are vectors of dispersal of propagules of plants and other organisms including pathogens, as well as nutrients and contaminants. Thus, through their movements they create functional connectivity between habitat patches. Most studies on connectivity provided by animals to date have focused on movements within similar habitat types. However, some waterbirds regularly switch between terrestrial, coastal and freshwater habitats throughout their daily routines. Lesser black-backed gulls that overwinter in Andalusia use different habitat types for roosting and foraging. In order to reveal their potential role in biovectoring among habitats, we created an inter-habitat connectivity network based on GPS tracking data. We applied connectivity measures by considering frequently visited sites as nodes, and flights as links, to determine the strength of connections in the network between habitats, and identify functional units where connections are more likely to happen. We acquired data for 42 tagged individuals (from five breeding colonies), and identified 5676 direct flights that connected 37 nodes. These 37 sites were classified into seven habitat types: reservoirs, natural lakes, ports, coastal marshes, fish ponds, rubbish dumps and ricefields. The Donana ricefields acted as the central node in the network based on centrality measures. Furthermore, during the first half of winter when rice was harvested, ricefields were the most important habitat type in terms of total time spent. Overall, 90% of all direct flights between nodes were between rubbish dumps (for foraging) and roosts in other habitats, thereby connecting terrestrial and various wetland habitats. The strength of connections decreased between nodes as the distance between them increased, and was concentrated within ten independent spatial and functional units, especially between December and February. The pivotal role for ricefields and rubbish dumps in the network, and their high connectivity with aquatic habitats in general, have important implications for biovectoring into their surroundings. (C) 2019 The Authors. Published by Elsevier B.V

    Endogenous Presentation of CD8+ T Cell Epitopes from Epstein-Barr Virus–encoded Nuclear Antigen 1

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    Epstein-Barr virus (EBV)–encoded nuclear antigen (EBNA)1 is thought to escape cytotoxic T lymphocyte (CTL) recognition through either self-inhibition of synthesis or by blockade of proteasomal degradation by the glycine-alanine repeat (GAr) domain. Here we show that EBNA1 has a remarkably varied cell type–dependent stability. However, these different degradation rates do not correspond to the level of major histocompatibility complex class I–restricted presentation of EBNA1 epitopes. In spite of the highly stable expression of EBNA1 in B cells, CTL epitopes derived from this protein are efficiently processed and presented to CD8+ T cells. Furthermore, we show that EBV-infected B cells can readily activate EBNA1-specific memory T cell responses from healthy virus carriers. Functional assays revealed that processing of these EBNA1 epitopes is proteasome and transporter associated with antigen processing dependent. We also show that the endogenous presentation of these epitopes is dependent on the newly synthesized protein rather than the long-lived stable EBNA1. Based on these observations, we propose that defective ribosomal products, not the full-length antigen, are the primary source of endogenously processed CD8+ T cell epitopes from EBNA1

    High volume fabrication of laser targets using MEMS techniques

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    The latest techniques for the fabrication of high power laser targets, using processes developed for the manufacture of Micro-Electro-Mechanical System (MEMS) devices are discussed. These laser targets are designed to meet the needs of the increased shot numbers that are available in the latest design of laser facilities. Traditionally laser targets have been fabricated using conventional machining or coarse etching processes and have been produced in quantities of 10s to low 100s. Such targets can be used for high complexity experiments such as Inertial Fusion Energy (IFE) studies and can have many complex components that need assembling and characterisation with high precision. Using the techniques that are common to MEMS devices and integrating these with an existing target fabrication capability we are able to manufacture and deliver targets to these systems. It also enables us to manufacture novel targets that have not been possible using other techniques. In addition, developments in the positioning systems that are required to deliver these targets to the laser focus are also required and a system to deliver the target to a focus of an F2 beam at 0.1Hz is discussed
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