Controllable direction of liquid jets generated by thermocavitation within a droplet.

A high-velocity fluid stream ejected from an orifice or nozzle is a common mechanism to produce liquid jets in inkjet printers or to produce sprays among other applications. In the present research, we show the generation of liquid jets of controllable direction produced within a sessile water droplet by thermocavitation. The jets are driven by an acoustic shock wave emitted by the collapse of a hemispherical vapor bubble at the liquid-solid/substrate interface. The generated shock wave is reflected at the liquid-air interface due to acoustic impedance mismatch generating multiple reflections inside the droplet. During each reflection, a force is exerted on the interface driving the jets. Depending on the position of the generation of the bubble within the droplet, the mechanical energy of the shock wave is focused on different regions at the liquid-air interface, ejecting cylindrical liquid jets at different angles. The ejected jet angle dependence is explained by a simple ray tracing model of the propagation of the acoustic shock wave inside the droplet

Dynamic constrained coalition formation among electric vehicles

Background: The use of electric vehicles (EVs) and vehicle-to-grid (V2G) technologies have been advocated as an efficient way to reduce the intermittency of renewable energy sources in smart grids. However, operating on V2G sessions in a cost-effective way is not a trivial task for EVs. The formation of coalitions among EVs has been proposed to tackle this problem. Methods: In this paper we introduce Dynamic Constrained Coalition Formation (DCCF), which is a distributed heuristic-based method for constrained coalition structure generation (CSG) in dynamic environments. In our approach, coalitions are formed observing constraints imposed by the grid. To this end, EV agents negotiate the formation of feasible coalitions among themselves. Results: Based on experiments, we show that DCCF is efficient to provide good solutions in a fast way. DCCF provides solutions whose quality approaches 98% of the optimum. In dynamically changing scenarios, DCCF also shows good results, keeping the agents payoff stable along time. Conclusions: Essentially, DCCF’s main advantage over traditional CSG algorithms is that its computational effort is very lower. On the other hand, unlike traditional algorithms, DCCF is suitable only for constraint-based problems

Synthesis and photochemical study of a new norbornadiene-derivative with potential as a molecular system for the storage of solar-thermal energy

Norbornadiene derivatives (NBD) have recently emerged as a promising alternative in the development of molecular systems for the storage of solar-thermal energy (MOST). In these systems, the energy is stored in the form of chemical bonds by photoisomerization reactions, and the stored energy can be released on demand in the form of heat. In this contribution, we present results regarding the photochemical behavior of a new NBD, i.e., 2-cyano-3-((4 (diethylamino)phenyl)ethinyl)norbornadiene (NBD1). This compound contains an electron-withdrawing group (CN), and an electron-donor group (ethinyl-derivative) in one of the double bonds of the bicycle-ring. As a consequence, a conjugated push-pull system was obtained, with led to an absorption band peaked at the visible region. The irradiation of NBD1 in toluene solution promotes the formation of the quadricyclane isomer, for which a maximum at about 310 nm was detected. Photoconversion seems to proceed almost quantitatively after ca. 30 minutes of irradiation.Agencia Nacional de Investigación e Innovació

U-Pb SHRIMP zircon dating of Grenvillian metamorphism in Western Sierras Pampeanas (Argentina) : correlation with the Arequipa-Antofalla craton and constraints on the extent of the Precordillera Terrane

The Sierras Pampeanas of Argentina, the largest outcrop of pre-Andean crystalline basement in southern South America, resulted from plate interactions along the proto-Andean margin of Gondwana, from as early as Mesoproterozoic to Late Paleozoic times (e.g., Ramos, 2004, and references therein). Two discrete Paleozoic orogenic belts have been recognized: the Early Cambrian Pampean belt in the eastern sierras, and the Ordovician Famatinian belt, which partially overprints it to the west (e.g., Rapela et al., 1998). In the Western Sierras Pampeanas, Mesoproterozoic igneous rocks (ca. 1.0–1.2 Ga) have been recognized in the Sierra de Pie de Palo (Fig. 1) (McDonough et al., 1993 M.R. McDonough, V.A. Ramos, C.E. Isachsen, S.A. Bowring and G.I. Vujovich, Edades preliminares de circones del basamento de la Sierra de Pie de Palo, Sierras Pampeanas occidentales de San Juán: sus implicancias para el supercontinente proterozoico de Rodinia, 12° Cong. Geol. Argentino, Actas vol. 3 (1993), pp. 340–342.McDonough et al., 1993, Pankhurst and Rapela, 1998 and Vujovich et al., 2004) that are time-coincident with the Grenvillian orogeny of eastern and northeastern North America (e.g., Rivers, 1997 and Corrievau and van Breemen, 2000). These Grenvillian-age rocks have been considered to be the easternmost exposure of basement to the Precordillera Terrane, a supposed Laurentian continental block accreted to Gondwana during the Famatinian orogeny (Thomas and Astini, 2003, and references therein). However, the boundaries of this Grenvillian belt are still poorly defined, and its alleged allochthoneity has been challenged (Galindo et al., 2004). Moreover, most of the Grenvillian ages so far determined relate to igneous protoliths, and there is no conclusive evidence for a Grenvillian orogenic belt, other than inferred from petrographic evidence alone (Casquet et al., 2001). We provide here the first evidence, based on U–Pb SHRIMP zircon dating at Sierra de Maz, for a Grenville-age granulite facies metamorphism, leading to the conclusion that a continuous mobile belt existed throughout the proto-Andean margin of Gondwana in Grenvillian times

Colorless devices and reception techniques for polarization multiplexed communications

Future optical networks call for flexible, high performance and low cost coherent optical receivers. We present here several advances towards such receivers, including integrated optical couplers with ultra-broad bandwidth, as well as novel reception techniques and architectures that will enable high performance coherent reception without filtering and polarization splitting elements.Universidad de Málaga - Campus de Excelencia Internacional Andalucía Tech. Spanish Ministry of Science under project TEC2013-46917-C2-1-

Safety and preliminary efficacy of vorinostat with R-EPOCH in high-risk HIV-associated non-Hodgkin\u27s lymphoma (AMC-075)

We performed a phase I trial of vorinostat (VOR) given on days 1 to 5 with R-EPOCH (rituximab plus etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin hydrochloride) in patients with aggressive HIV-associated non-Hodgkin lymphoma. VOR was tolerable at 300 mg and seemingly efficacious with chemotherapy with complete response rate of 83% and 1-year event-free survival of 83%. VOR did not significantly alter chemotherapy steady-state concentrations, CD4+ cell counts, or HIV viral loads. Vorinostat (VOR), a histone deacetylase inhibitor, enhances the anti-tumor effects of rituximab (R) and cytotoxic chemotherapy, induces viral lytic expression and cell killing in Epstein-Barr virus-positive (EBV+) or human herpesvirus-8-positive (HHV-8+) tumors, and reactivates latent human immunodeficiency virus (HIV) for possible eradication by combination antiretroviral therapy (cART). We performed a phase I trial of VOR given with R-based infusional EPOCH (etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin hydrochloride) (n = 12) and cART in aggressive HIV-associated B-cell non-Hodgkin lymphoma (NHL) in order to identify safe dosing and schedule. VOR (300 or 400 mg) was given orally on days 1 to 5 with each cycle of R-EPOCH for 10 high-risk patients with diffuse large B-cell lymphoma (1 EBV+), 1 EBV+/HHV-8+ primary effusion lymphoma, and 1 unclassifiable NHL. VOR was escalated from 300 to 400 mg using a standard 3 + 3 design based on dose-limiting toxicity observed in cycle 1 of R-EPOCH. The recommended phase II dose of VOR was 300 mg, with dose-limiting toxicity in 2 of 6 patients at 400 mg (grade 4 thrombocytopenia, grade 4 neutropenia), and 1 of 6 treated at 300 mg (grade 4 sepsis from tooth abscess). Neither VOR, nor cART regimen, significantly altered chemotherapy steady-state concentrations. VOR chemotherapy did not negatively impact CD4+ cell counts or HIV viral loads, which decreased or remained undetectable in most patients during treatment. The response rate in high-risk patients with NHL treated with VOR(R)-EPOCH was 100% (complete 83% and partial 17%) with a 1-year event-free survival of 83% (95% confidence interval, 51.6%-97.9%). VOR combined with R-EPOCH was tolerable and seemingly efficacious in patients with aggressive HIV-NHL

El icnogénero Zoophycos y su valor sedimentológico y paleoambiental

El icnogénero Zoophycos (Cancellophynts) puede proporcionar datos sedimentológicos de sumo interés, lo cual viene favorecido por: su fácil reconocimiento (tanto en series estratigráficas como en testigos de sondeos), relativa frecuencia de aparición, y amplia reparticibn temporal (Ordovicico - Cuaternario)