Parametric model of spectral envelope to synthesize realistic intensity variations in singing voice

2014 IEEE International Conference on Acoustic, Speech and Signal Processing (ICASSP), pp. 634 - 638In this paper, we propose a method to synthesize the natural variations of spectral envelope as intensity varies in singing voice. To this end, we propose a parametric model of spectral envelope based on novel 4-pole resonators as formant filters. This model has been used to analyse 60 vowels sung at different intensities in order to define a set of functions describing the global variations of parameters along intensity. These functions have been used to modify the intensity of 16 recorded vowels and 8 synthetic vowels generated with Vocaloid. The realism of the transformations performed with our approach has been evaluated by four amateurmusicians in comparison to Melodyne for real sounds and to Vocaloid for synthetic sounds. The proposed approach has been proved to achieve more realistic sounds than Melodyne and Vocaloid, especially for loud-to-weak transformations.This work has been funded by the Ministerio de Economía y Competitividad of the Spanish Government under Project No. TIN2010-21089-C03- 02 and Project No. IPT-2011-0885-430000, by the Junta de Andaluc´ıa under Project No. P11-TIC-7154 and by the Ministerio de Educaci ón, Cultura y Deporte through the ‘Programa Nacional de Movilidad de Recursos Humanos del Plan Nacional de I-D+i 2008-2011, prorrogado por Acuerdo de Consejo de Ministros de 7 de octubre de 2011’. The work has been done in the context of Campus de Excelencia Internacional Andalucía Tech, Universidad de Málaga

The importance of F0 tracking in query-by-singing-humming

In this paper, we present a comparative study of several state-of-the-art F0 trackers applied to the context of query-by-singing-humming (QBSH). This study has been carried out using the well known, freely available, MIR-QBSH dataset in different conditions of added pub-style noise and smartphone-style distortion. For audio-to-MIDI melodic matching, we have used two state-of-the-art systems and a simple, easily reproducible baseline method. For the evaluation, we measured the QBSH performance for 189 different combinations of F0 tracker, noise/distortion conditions and matcher. Additionally, the overall accuracy of the F0 transcriptions (as defined in MIREX) was also measured. In the results, we found that F0 tracking overall accuracy correlates with QBSH performance, but it does not totally measure the suitability of a pitch vector for QBSH. In addition, we also found clear differences in robustness to F0 transcription errors between different matchers.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. This work has been funded by the Ministerio de Economía y Competitividad of the Spanish Government under Project No. TIN2013-47276-C6-2-R and by the Junta de Andalucía under Project No. P11-TIC-7154

Una herramienta para monitorear sequías en regiones áridas y semiáridas de Patagonia Norte

La variabilidad ambiental es una característica de regiones pastoriles áridas y semiáridas, siendo la sequía uno de los principales problemas en sistemas ganaderos extensivos, con implicancias productivas y económicas tanto a escala predial como regional. El monitoreo regional de los procesos de sequía es una herramienta fundamental y necesaria, como complemento de propuestas y manejos adaptativos activos que busquen mitigar los impactos sobre la producción. En el presente artículo proponemos una herramienta para el monitoreo de sequías en zonas áridas y semiáridas, basada en datos provistos por sensores remotos. El objetivo fue desarrollar un sistema de monitoreo basado en un índice espectral, desagregando la heterogeneidad biofísica regional en unidades homogéneas, y relacionándola con los momentos clave de decisiones asociadas al manejo ganadero tradicional, en sistemas de producción ovina de Patagonia Norte. Esta integración permite acercar esta herramienta a la toma de decisiones a escala regional, fundamentalmente para instituciones y organizaciones locales, y colaborar con información en el diseño y desarrollo de políticas vinculadas al manejo ganadero adaptativo. Finalmente, discutimos los alcances de la herramienta y los desafíos futuros, asociados al desarrollo de sistemas de alerta temprana y mitigación de sequías en regiones áridas y semiáridas.Environmental variability is a constant feature in arid and semiarid rangeland regions, being drought one of the main problems in extensive livestock production, with productive and economic impacts both at farm and regional scales. Regional monitoring of drought processes is a key and necessary tool, as a complement for active adaptive proposals and management, aimed at mitigation on production impacts. In this article, we propose a tool for drought monitoring in arid and semiarid areas, based on remote sensing data. The aim was to develop a monitoring system based on a spectral index, disaggregating regional biophysical heterogeneity into homogeneous units, by linking them to key decision moments associated with traditional livestock management in sheep farming systems from Northern Patagonia. Such integration allows bringing this tool closer to regional decision making, basically for local institutions and organizations, and give support with information for policy design and development related to adaptive livestock management. Finally, we discuss the scope of this tool and future challenges, regarding the development of early warning and drought mitigation systems in arid and semiarid regions.EEA BarilocheFil: Easdale, Marcos Horacio. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche. Área de Desarrollo Rural; ArgentinaFil: Lopez, Dardo Ruben. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche. Área de Recursos Naturales; ArgentinaFil: Bianchi, Emilio. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Bruzzone, Octavio Augusto. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche; ArgentinaFil: Villagra, Edgar Sebastian. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche; ArgentinaFil: Siffredi, Guillermo Lorenzo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche. Área de Recursos Naturales; ArgentinaFil: Gaitan, Juan Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche. Área de Recursos Naturales; ArgentinaFil: Umaña, Fernando. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche; ArgentinaFil: Oricchio, Patricio. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Clima y Agua; Argentin

The OTELO survey: A case study of [O III] lambda 4959,5007 emitters at z=0.83

Context. The OSIRIS Tunable Filter Emission Line Object (OTELO) survey is a very deep, blind exploration of a selected region of the Extended Groth Strip and is designed for finding emission-line sources (ELSs). The survey design, observations, data reduction, astrometry, and photometry, as well as the correlation with ancillary data used to obtain a final catalogue, including photo-z estimates and a preliminary selection of ELS, were described in a previous contribution. Aims. Here, we aim to determine the main properties and luminosity function (LF) of the [O III] ELS sample of OTELO as a scientific demonstration of its capabilities, advantages, and complementarity with respect to other surveys. Methods. The selection and analysis procedures of ELS candidates obtained using tunable filter pseudo-spectra are described. We performed simulations in the parameter space of the survey to obtain emission-line detection probabilities. Relevant characteristics of [O III] emitters and the LF ([O III]), including the main selection biases and uncertainties, are presented. Results. From 541 preliminary emission-line source candidates selected around z = 0.8, a total of 184 sources were confirmed as [O III] emitters. Consistent with simulations, the minimum detectable line flux and equivalent width in this ELS sample are ∼5 × 10−19 erg s−1 cm2 and ∼6 Å, respectively. We are able to constrain the faint-end slope (α = −1.03 ± 0.08) of the observed LF ([O III]) at a mean redshift of z = 0.83. This LF reaches values that are approximately ten times lower than those from other surveys. The vast majority (84%) of the morphologically classified [O III] ELSs are disc-like sources, and 87% of this sample is comprised of galaxies with stellar masses of M⋆ <  1010 M⊙

Design and rationale of a multicentre, randomised, double-blind, placebo-controlled clinical trial to evaluate the effect of vitamin D on ventricular remodelling in patients with anterior myocardial infarction: the VITamin D in Acute Myocardial Infarction (VITDAMI) trial

Introduction:Decreased plasma vitamin D (VD) levels are linked to cardiovascular damage. However, clinical trials have not demonstrated a benefit of VD supplements on left ventricular (LV) remodelling. Anterior ST-elevation acute myocardial infarction (STEMI) is the best human model to study the effect of treatments on LV remodelling. We present a proof-of-concept study that aims to investigate whether VD improves LV remodelling in patients with anterior STEMI. Methods and analysis:The VITamin D in Acute Myocardial Infarction (VITDAMI) trial is a multicentre, randomised, double-blind, placebo-controlled trial. 144 patients with anterior STEMI will be assigned to receive calcifediol 0.266 mg capsules (Hidroferol SGC)/15 days or placebo on a 2:1 basis during 12 months. Primary objective:to evaluate the effect of calcifediol on LV remodelling defined as an increase in LV end-diastolic volume >= 10\% (MRI). Secondary objectives:change in LV end-diastolic and end-systolic volumes, ejection fraction, LV mass, diastolic function, sphericity index and size of fibrotic area; endothelial function; plasma levels of aminoterminal fragment of B-type natriuretic peptide, galectin-3 and monocyte chemoattractant protein-1; levels of calcidiol (VD metabolite) and other components of mineral metabolism (fibroblast growth factor-23 (FGF-23), the soluble form of its receptor klotho, parathormone and phosphate). Differences in the effect of VD will be investigated according to the plasma levels of FGF-23 and klotho. Treatment safety and tolerability will be assessed. This is the first study to evaluate the effect of VD on cardiac remodelling in patients with STEMI. Ethics and dissemination: This trial has been approved by the corresponding Institutional Review Board (IRB) and National Competent Authority (Agencia Espanola de Medicamentos y Productos Sanitarios (AEMPS)). It will be conducted in accordance with good clinical practice (International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use-Good Clinical Practice (ICH-GCP)) requirements, ethical principles of the Declaration of Helsinki and national laws. The results will be submitted to indexed medical journals and national and international meetings.The VITDAMI trial is an investigator initiated study, sponsored by the Instituto de Investigacion Sanitaria Fundacion Jimenez Diaz (IIS-FJD). Funding has been obtained from Fondo de Investigaciones Sanitarias (PI14/01567; http://www.isciii.es/) and Spanish Society of Cardiology (http://secardiologia.es/). In addition, the study medication has been provided freely by the pharmaceutical Company FAES FARMA S.A. (Leioa, Vizcaya, Spain; http://faesfarma.com/). This company was the only funder who collaborated in study design (IG-H).S

Good practice regarding smoking cessation management in Spain: Challenges and opportunities for primary care physicians and nurses

INTRODUCTION We analyze the activities carried out by primary care (PC) physicians and nurses with respect to smoking cessation and evaluate their self-reported training, knowledge, and behavior. METHODS A cross-sectional study was conducted including 1514 PC physicians and nurses from June 2016 to March 2017, in Spain. The main variable was Good Practice (GP) in attention to smokers. To identify associated factors, a multilevel logistic regression model was used adjusted for sex, age, type of center, contract, years of employment, tobacco consumption, and self-reported training/knowledge. RESULTS Of the 792 physicians and 722 nurses, 48.6% referred to GP in smoking cessation management. The finding related to: being a non-smoker (OR=1.8; 95% CI: 1.2-2.5) or ex-smoker (OR= 1.4; 95% CI: 1.02-2.1), having a good level of knowledge (OR=1.8; 95% CI: 1.3-2.4) and training (OR=2.4; 95% CI: 1.8-3.2), and, to a lesser extent, being female (OR=1.3; 95% CI: 1.03-1.7), and work experience >10 years (OR=1.4; 95% CI: 1.03-1.9). The main GP barriers were: lack of time (45.5%), organizational problems (48.4%), and 35.4% lack of training. CONCLUSIONS The GP of PC physicians and nurses regarding smoking cessation management is related to being non-smokers or ex-smokers, and having sufficient training and knowledge. Lack of time and organizational problems were considered to be the main barriers. The promotion of training activities in the Spanish National Health Service with the support of scientific societies is required

An analysis of the control hierarchy modeling of the CMS detector control system

The supervisory level of the Detector Control System (DCS) of the CMS experiment is implemented using Finite State Machines (FSM), which model the behaviours and control the operations of all the sub-detectors and support services. The FSM tree of the whole CMS experiment consists of more than 30.000 nodes. An analysis of a system of such size is a complex task but is a crucial step towards the improvement of the overall performance of the FSM system. This paper presents the analysis of the CMS FSM system using the micro Common Representation Language 2 (mcrl2) methodology. Individual mCRL2 models are obtained for the FSM systems of the CMS sub-detectors using the ASF+SDF automated translation tool. Different mCRL2 operations are applied to the mCRL2 models. A mCRL2 simulation tool is used to closer examine the system. Visualization of a system based on the exploration of its state space is enabled with a mCRL2 tool. Requirements such as command and state propagation are expressed using modal mu-calculus and checked using a model checking algorithm. For checking local requirements such as endless loop freedom, the Bounded Model Checking technique is applied. This paper discusses these analysis techniques and presents the results of their application on the CMS FSM system

Tecnologías ganaderas en rodeos de cría del este del Chaco, Argentina

Es cada vez mayor el interés por mejorar los parámetros productivos de la ganadería bovina, para lo que resulta imprescindible identificar los problemas que dificultan la adopción de las tecnologías que permiten incrementar su productividad. Esta publicación contiene la información relevada, sistematizada y analizada proveniente de encuestas realizadas a productores en el área de influencia de la EEA Colonia Benítez de INTA, ubicada en el este de la provincia del Chaco. El relevamiento se realizó de forma simultánea en las Agencias de Extensión Rural de Las Palmas, Basail, Makallé y en la Oficina de Colonia Benítez con la participación de distintos estratos de productores. Se evaluaron tecnologías relacionadas al manejo del rodeo, reproducción, sanidad, nutrición, bienestar animal, así como la gestión integral de la empresa ganadera. Los resultados logrados se presentan de manera ordenada definiendo las tecnologías consultadas, los valores obtenidos en cada estrato de productores, junto a relatos breves en primera persona del “conocimiento y uso” de las tecnologías analizadas. La información resulta de utilidad para construir propuestas de intervención teniendo en cuenta.EEA Colonia BenítezFil: Verdoljak, Juan Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez; ArgentinaFil: Gomez, Viviana Daniela. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez; ArgentinaFil: Rossner, Maria Victoria. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez; ArgentinaFil: Pellerano, Liliana Laura. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benítez; ArgentinaFil: Famin, Lucia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez. Agencia de Extensión Rural Las Palmas; ArgentinaFil: Vagabculov, Javier. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez; ArgentinaFil: Monteros, Diego Ezequiel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez; ArgentinaFil: Lestani Sablich, Mariano. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benítez. Agencia de Extensión Rural Makallé; ArgentinaFil: Geijo, Angel Ruben. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez. Agencia de Extensión Rural Basail; ArgentinaFil: Fernandez, Abel Leopoldo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez. Agencia de Extensión Rural Las Palmas; ArgentinaFil: Pamies, Marcelo Eduardo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benítez; ArgentinaFil: Monicault, Luis Ademar. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez; ArgentinaFil: Davalos, Carlos. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez. Agencia de Extensión Rural Basail; ArgentinaFil: Saez, Roberto Alonso. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez; ArgentinaFil: Vagabculow, Jorge Leandro. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez. Agencia de Extensión Rural Las Palmas; ArgentinaFil: Di Lorenzo, Elio Luis. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez; ArgentinaFil: Rosello Brajovich, José Emilio. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benítez; Argentin

Effectiveness of a strategy that uses educational games to implement clinical practice guidelines among Spanish residents of family and community medicine (e-EDUCAGUIA project):A clinical trial by clusters

This study was funded by the Fondo de Investigaciones Sanitarias FIS Grant Number PI11/0477 ISCIII.-REDISSEC Proyecto RD12/0001/0012 AND FEDER Funding.Background: Clinical practice guidelines (CPGs) have been developed with the aim of helping health professionals, patients, and caregivers make decisions about their health care, using the best available evidence. In many cases, incorporation of these recommendations into clinical practice also implies a need for changes in routine clinical practice. Using educational games as a strategy for implementing recommendations among health professionals has been demonstrated to be effective in some studies; however, evidence is still scarce. The primary objective of this study is to assess the effectiveness of a teaching strategy for the implementation of CPGs using educational games (e-learning EDUCAGUIA) to improve knowledge and skills related to clinical decision-making by residents in family medicine. The primary objective will be evaluated at 1 and 6months after the intervention. The secondary objectives are to identify barriers and facilitators for the use of guidelines by residents of family medicine and to describe the educational strategies used by Spanish teaching units of family and community medicine to encourage implementation of CPGs. Methods/design: We propose a multicenter clinical trial with randomized allocation by clusters of family and community medicine teaching units in Spain. The sample size will be 394 residents (197 in each group), with the teaching units as the randomization unit and the residents comprising the analysis unit. For the intervention, both groups will receive an initial 1-h session on clinical practice guideline use and the usual dissemination strategy by e-mail. The intervention group (e-learning EDUCAGUIA) strategy will consist of educational games with hypothetical clinical scenarios in a virtual environment. The primary outcome will be the score obtained by the residents on evaluation questionnaires for each clinical practice guideline. Other included variables will be the sociodemographic and training variables of the residents and the teaching unit characteristics. The statistical analysis will consist of a descriptive analysis of variables and a baseline comparison of both groups. For the primary outcome analysis, an average score comparison of hypothetical scenario questionnaires between the EDUCAGUIA intervention group and the control group will be performed at 1 and 6months post-intervention, using 95% confidence intervals. A linear multilevel regression will be used to adjust the model. Discussion: The identification of effective teaching strategies will facilitate the incorporation of available knowledge into clinical practice that could eventually improve patient outcomes. The inclusion of information technologies as teaching tools permits greater learning autonomy and allows deeper instructor participation in the monitoring and supervision of residents. The long-term impact of this strategy is unknown; however, because it is aimed at professionals undergoing training and it addresses prevalent health problems, a small effect can be of great relevance. Trial registration: ClinicalTrials.gov: NCT02210442.Publisher PDFPeer reviewe