Cost efficiency and resistance to chemical attack of a fly ash geopolymeric mortar versus epoxy resin and acrylic paint coatings

This article presents results of an experimental investigation on the resistance to chemical attack (with sulphuric, hydrochloric and nitric acid) of several materials: OPC concrete, high-performance concrete, epoxy resin, acrylic painting and a fly ash-based geopolymeric mortar). Three types of acids with three high concentrations (10, 20 and 30%) were used to simulate long-term degradation. A cost analysis was also performed. The results show that the epoxy resin has the best resistance to chemical attack independently of the acid type and the acid concentration. However, the cost analysis shows that the epoxy resin-based solution is the least cost-efficient solution being 70% above the cost efficiency of the fly ash-based geopolymeric mortar

Composition and antioxidant activity of thymus vulgaris volatiles: comparison between supercritical fluid extraction and hydrodistillation

Supercritical fluid extraction (SEE) of the volatile oil from Thymus vulgaris L. aerial flowering parts was performed under different conditions of pressure, temperature, mean particle size and CO2 flow rate and the correspondent yield and composition were compared with those of the essential oil isolated by hydrodistillation (HD). Both the oils were analyzed by GC and GC-MS and 52 components were identified. The main volatile components obtained were p-cymene (10.0-42.6% for SFE and 28.9-34.8% for HD), gamma-terpinene (0.8-6.9% for SFE and 5.1-7.0% for HD), linalool (2.3-5.3% for SFE and 2.8-3.1% for HD), thymol (19.5-40.8% for SFE and 35.4-41.6% for HD), and carvacrol (1.4-3.1% for SFE and 2.6-3.1% for HD). The main difference was found to be the relative percentage of thymoquinone (not found in the essential oil) and carvacryl methyl ether (1.0-1.2% for HD versus t-0.4 for SFE) which can explain the higher antioxidant activity, assessed by Rancimat test, of the SFE volatiles when compared with HD. Thymoquinone is considered a strong antioxidant compound

Volatiles of the Inflorescences of the Madeiran Orchids, Goodyera macrophylla Lowe and Gennaria diphylla (Link) Parl. and Their Role in Pollination

Goodyera macrophylla, considered a rare endemic, and Gennaria diphylla are two native terrestrial Orchidaceae species that can be found mainly in Madeiran Laurisilva. The volatile compounds contributing to the floral scent of these two Madeiran orchids were analysed and compared for the first time. The volatiles, isolated by distillation-extraction in a Likens-Nickersontype apparatus, and those extracted by headspace sorption, were analysed by GC and GC-MS. The main volatile components isolated by distillation-extraction were γ-terpinene (13%) and n-nonanal (11%) in G. macrophylla and n-octacosane (19%) and n-heptacosane (13%) in G. diphylla. The main volatile components isolated by headspace sorption were p-cymene (21%), α-pinene (15%) and linalool (14%) in G. macrophylla and cis-arbusculone (28%) and lilac alcohol (26%) in G. diphylla. The importance of the volatiles in the pollination of these orchids is discussed.Portuguese Foundation for the Science and Technology (FCT, Fundação para a Ciência e Tecnologia) has sponsored this work, through the Centre of Macaronesian Studies (CEM). The authors are also grateful to the Madeiran Centre of Science and Technology (CITMA) for financial support.info:eu-repo/semantics/publishedVersio

Caracterización Proteómica del trombo coronario en pacientes con infarto agudo de miocardio con elevación del segmento ST

Comunicaciones a congreso

Detecting antibody-labeled BCG MNPs using a magnetoresistive biosensor and magnetic labeling technique

Tuberculosis is still a major global health concern, causing the estimated death of 1.5 million people per year and being associated with high morbidity. The development of point-of-care diagnostic tools for tuberculosis is mandatory, especially because the fast and accurate detection of the slow-growing Mycobacterium tuberculosis by the conventional diagnostic tests is difficult. The objective of this work was to develop the first steps to achieve a portable method for the diagnosis of tuberculosis, by a sandwich-immunoassay combined with magnetoresistive biochip technology. With the purpose of conjugating 250 nm streptavidin-coated magnetic nanoparticles with anti-M. tuberculosis biotinylated antibodies, Mycobacterium bovis Bacillus Calmette-Guerin was used as a surrogate for M. tuberculosis bacteria. After magnetic capture, target bacteria were brought in contact with the surface of the magnetoresistive biochip previously functionalized with a secondary anti-M. tuberculosis antibody. Magnetically labeled cells were detected by an array of spin-valve sensors, which change their electrical resistance in the presence of the fringe field of the magnetic particles. Optimization studies on the efficiency of the magnetic capture and further recognition of the bacteria by the secondary antibody on the biochip surface were conducted. The results on the magnetoresistive biochip showed a clear difference in the signal between specific and control ( nonspecific) sensors, suggesting the usefulness of this technique as a potential biorecognition tool for the development of a point-of-care diagnostic method for tuberculosis.Acknowledgments: Teresa Barroso thanks FCT for her PhD Grant SFRH/BD/33904/2009.info:eu-repo/semantics/publishedVersio

La innovación tecnológica desde la promoción de vivienda pública: el concurso de innovación técnica INCASOL

El INCASOL convocó en 2006 y 2007 el Concurso de Innovación Tecnológica, que se planteaba con el objetivo de incorporar mejoras en la construcción de viviendas, concretamente de: la calidad, la seguridad, el control en la ejecución, la sostenibilidad y la eficiéncia energética, y la eficácia en la promoción. El modelo de Concurso fue el de proyecto y obra, de manera que se pretendía alcanzar la sinergia resultante de la colaboración del arquitecto autor del proyecto, el industrial fabricante del sistema y la empresa de construcción adjudicataria, desde el inicio del proyecto. Se premiaron seis proyectos que en su conjunto caracterizan de forma clara las posibilidades de la innovación e industrialización de la vivienda en España. En la segunda mitad del 2008 se iniciaron las obras de construcción de los primeros proyectos.Peer ReviewedPostprint (published version

Using integrated wildlife monitoring to prevent future pandemics through one health approach

In the One Health context, Integrated Wildlife Monitoring (IWM) merges wildlife health monitoring (WHM) and host community monitoring to early detect emerging infections, record changes in disease dynamics, and assess the impact of interventions in complex multi-host and multi-pathogen networks. This study reports the deployment and results obtained from a nationwide IWM pilot test in eleven sites representing the habitat diversity of mainland Spain. In each study site, camera-trap networks and sampling of indicator species for antibody and biomarker analysis were used to generate information. The results allowed identifying differences in biodiversity and host community characteristics among the study sites, with a range of 8 to 19 relevant host species per point. The Eurasian wild boar (Sus scrofa) was the most connected and central species of the host communities, becoming a key target indicator species for IWM. A negative relationship between biodiversity and disease risk was detected, with a lower number and prevalence of circulating pathogens in the sites with more species in the community and larger network size. However, this overall trend was modified by specific host-community and environmental factors, such as the relative index of wild boar - red deer interactions or the proximity to urban habitats, suggesting that human-driven imbalances may favour pathogen circulation. The effort of incorporating wildlife population monitoring into the currently applied WHM programs to achieve effective IWM was also evaluated, allowing to identify population monitoring as the most time-consuming component, which should be improved in the future. This first nationwide application of IWM allowed to detect drivers and hotspots for disease transmission risk among wildlife, domestic animals, and humans, as well as identifying key target indicator species for monitoring. Moreover, anthropogenic effects such as artificially high wildlife densities and urbanisation were identified as risk factors for disease prevalence and interspecific transmission

Cada coisa em seu lugar: ensaio de interpretação do discurso de um museu de história

O Museu Histórico Nacional, situado no Rio de Janeiro, foi criado em 1922, como parte das comemorações do Centenário da Independência do Brasil. Ao longo dos seguintes 38 anos, foi dirigido por Gustavo Barroso. Este intelectual, figura bastante típica da “república das letras” brasileira, imprimiu no MHN uma forte marca pessoal, cristalizada no discurso conservador expresso pelas exposições. Baseado nas formulações teóricas de Carlo Ginzburg, conforme apresentadas em um artigo intitulado “Sinais - raízes de um paradigma indiciário”, bem como em diversos textos que abordam museus como discursos, o autor analisa a exposição do MHN nos anos 30, 40 e 50. Apoiando-se também na produção científica dos conservadores, publicada em livros e na revista institucional, os “Anais do Museu Histórico Nacional”, procura ver o circuito como representação das posições ocupadas pelos “agentes ativos da história” - aristocracia, funcionários públicos civis e militares, dentre outras categorias - em relação a uma categoria não claramente definida, o “povo”, que foi representada através da ausência

Un nuevo ensayo para la evaluación de los encolados composite-composite

VI CONGRESO NACIONAL DE MATERIALES COMPUESTOS. Celebrado en Valencia, 27-29 de junio de 2005En el presente trabajo se propone una nueva configuración de ensayo para la determinación de la tenacidad a fractura interlaminar GIC en encolados compositecomposite. Las configuraciones actuales que fijan las normas de ensayo para la determinación de GIC se realizan de forma que la carga no permanece constante y el cálculo de GIC queda altamente dependiente de las propiedades de los adherentes, parámetros geométricos y demás variables que no representan la calidad del encolado ni la preparación superficial. La configuración propuesta origina el avance de la grieta de interfase bajo una carga media constante y pretende corregir las limitaciones mencionadas

The Halogen Effect on the Magnetic Behaviour of Dimethylformamide Solvates in [Fe(halide-salEen)2]BPh4

Funding Research was funded by Fundação para a Ciência e a Tecnologia (FCT): projects UIDB/00100/2020, UIDP/00100/2020, LA/P/0056/2020, UIDB/04046/2020, UIDP/04046/2020, UIDB/50006/2020, UIDP/50006/2020 and LA/P/0008/2020, UIDB/04378/2020, UIDP/04378/2020, and LA/P/0140/2020, PTDC/QUI-QFI/29236/2017, PTDCQUI-QIN0252_2021, CEECIND/00509/2017; Fonds de la Recherche Scientifique (FNRS): PDR T.0095.21); Portugal2020: CENTRO-01-0145-FEDER-000018; Royal Society of Chemistry (RSC): R21-7511142525. Acknowledgments Centro de Química Estrutural (CQE) and Institute of Molecular Sciences (IMS) acknowledge the financial support of Fundação para a Ciência e a Tecnologia (FCT): Projects UIDB/00100/2020, UIDP/00100/2020, and LA/P/0056/2020, respectively. BioISI acknowledges FCT for financial support (UIDB/04046/2020, UIDP/04046/2020). This work was supported by the FNRS (PDR T.0095.21). Clara S. B. Gomes acknowledges the Associate Laboratory for Green Chemistry—LAQV, the Applied Molecular Biosciences Unit—UCIBIO and Associated Laboratory i4HB, which are financed by national funds from FCT (UIDB/50006/2020, UIDP/50006/2020 and LA/P/0008/2020, UIDB/04378/2020 and UIDP/04378/2020, and LA/P/0140/2020, respectively). Sónia Barroso thanks project SmartBioR for financial support (CENTRO-01-0145-FEDER-000018)and Centro de Química Estrutural for the access to crystallography facilities. Nuno A. G. Bandeira gratefully acknowledges the NanoBioSolutions FCT grant PTDC/QUI-QFI/29236/2017 for the computational infrastructure. Paulo N. Martinho thanks FCT and RSC for financial support (grants PTDCQUI-QIN0252_2021 and R21-7511142525). Paulo N. Martinho also thanks FCT for the contract CEECIND/00509/2017.Complexes [Fe(X-salEen)2]BPh4·DMF, with X = Br (1), Cl (2), and F (3), were crystallised from N,N′-dimethylformamide with the aim of understanding the role of a high boiling point N,N′-dimethylformamide solvate in the spin crossover phenomenon. The counter ion was chosen for only being able to participate in weak intermolecular interactions. The compounds were structurally characterised by single crystal X-ray diffraction. Complex 1 crystallised in the orthorhombic space group P212121, and complexes 2 and 3 in the monoclinic space group P21/n. Even at room temperature, low spin was the predominant form, although complex 2 exhibited the largest proportion of the high-spin species according to both the magnetisation measurements and the Mössbauer spectra. Density Functional Theory calculations were performed both on the periodic solids and on molecular models for complexes 1–3 and the iodide analogue 4. While all approaches reproduced the experimental structures very well, the energy balance between the high-spin and low-spin forms was harder to reproduce, though some calculations pointed to the easier spin crossover of complex 2, as observed. Periodic calculations with the functional PBE led to very similar ΔEHS-LS values for all complexes but showed a preference for the low-spin form. However, the single-point calculations with B3LYP* showed, for the model without solvate, that the Cl complex should undergo spin crossover more easily. The molecular calculations also reflected this fact, which was more clearly defined when the cation–anion–solvate model was used. In the other models there was not much difference between the Cl, Br, and I complexes.publishersversionpublishe