681 research outputs found

    Influence of the soil water content and distribution on both the hydraulic and transpiration performance of 'Manzanilla' olive trees

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    8 páginas, 4 figuras, 20 referencias.-- VI International Symposium on Irrigation of Horticultural Crops, celebrado del 2-6 de noviembre de 2006 en Viña del Mar, Chile.-- [email protected] work was made with mature 'Manzanilla' olive trees in an orchard of a semi-arid area in southern Spain. Three water treatments were considered: Rainfed, in which the trees had rainfall as the only source of water supply; FAO, in which the trees were under localized irrigation to replace the crop water demand, with some roots left in drying soil; Pond, in which the whole rootzones of the trees were maintained under non-limiting soil water conditions for the whole dry season. Our aim was to obtain information on the mechanisms behind the reduction of transpiration (Ep) in the FAO trees, as compared to the Pond trees. Our results show a near-isohydric behaviour of the FAO trees, i.e. those trees under localized irrigation in which some roots are left in drying showed lower stomatal conductance than the Pond trees in which all roots were in wetted soil. This helped the FAO trees to maintain similar leaf water potentials than the Pond trees. In addition, the FAO trees maintained a constant difference between the water potential of the canopy and that in the soil. This has been described as an isohydrodynamic behaviour, and it is thought to be an improvement over a typically anisohydric behaviour. These mechanisms were behind the similar values of tree hydraulic conductance (K p) found in the FAO and Pond treatments. The Rainfed trees showed lower Kp values because of the low Ep values of those trees, due to the low soil water availability in that treatment. Our results show, however, that the Rainfed trees were able to maintain similar values of Kp all throughout the dry season, which shows that the hydraulic efficiency of the xylem of those trees was little affected by embolism, despite of the high demanding conditions in the area.This work has been funded by the Spanish Ministry of Education and Science, research project No.AGL2006-04666/AGR, and by the EU, research project ref. STREP 023120.Peer Reviewe

    Landscape evolution and geodynamic controls in the Gulf of Cadiz (Huelva coast, SW Spain) during the Late Quaternary

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    The coastal evolution of the El Abalario area (Huelva, southern Spain) during the Late Pleistocene and Holocene is reinterpreted after a refinement of the available geochronology by means of optically stimulated luminescence (OSL) dating. New data come from the analysis of soft sediment deformation, palaeosols, geomorphological mapping, and published seismic surveys on the onshore and offshore Gulf of Cadiz. The present structure of El Abalario dome resulted from the complex interaction of littoral-catchment processes and sea-level changes upon an emergent coastal plain, conditioned by the upwarping of the underlying Pliocene - Pleistocene prograding deltaic sequence. Upwarping is probably related to escape of over-pressurized fluids, accompanied by dewatering, prior to (?) and during OIS (Oxygen Isotopic Stage) 5. Continued upwarping produced the large NW - SE gravitational fault of Torre del Loro (TLF) in the southwestern flank of the dome, roughly parallel to the present coastline during OIS 5 - OIS 4. The resulting escarpment favoured the accumulation of aeolian sand dunes (units U1, U2, and U3) from OIS 5 to early OIS 1. Unit U1 (OIS 5) ends upwards in a supersurface with a thick weathering profile that suggests moist and temperate climatic conditions. Unit U2 accumulated mainly during OIS 4 and OIS 3 with prevailing W/E winds. The supersurface between U2 and U3 records a part of OIS 2, with relative low sea level. Sedimentation of unit U3 took place during the Last Deglaciation (radiocarbon and OSL ages) with prevailing W/SW winds, under a temperate moist climate, that became more arid towards the top (Holocene). A major supersurface with an iron crust-like layer (SsFe) developed during the Holocene Climatic Optimum (OIS 1) under wetter and more temperate conditions than before, fossilizing the TLF. The supersurface is covered by younger aeolian dunes (U4, U5, U6, and U7) transported by W - SW winds since the Late Neolithic - Chalcolithic cultural period (̃5.0 ky cal BP).Financial support from Spanish Projects BTE2002-1065 and BTE2002-1691. This is a contribution to IGCP 495 and to the INQUA “Coastal and Marine Processes Commission”

    Análisis arqueosismológico del conjunto arqueológico romano de Mulva- Munigua (Sevilla, España). Resultados preliminares

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    El conjunto arqueológico romano de Mulva-Munigua (Sevilla, España) presenta daños en las edificaciones que pueden ser interpretadas como resultado de la ocurrencia de un evento sísmico (Efectos Arqueológicos de los Terremotos: EAEs) a finales del siglo III A.D., fecha coincidente con el inicio del periodo de declive económico de este asentamiento romano. Para intentar establecer el posible origen sísmico de las deformaciones, se ha procedido al inventario y análisis de las estructuras deformadas presentes en el yacimiento. No obstante, algunas de estas deformaciones también se pueden interpretar como resultado de procesos gravitaciones asociados a la ladera Este de la colina sobre la que se sitúa parte del yacimiento. Las direcciones de máxima deformación (ey) obtenidas del análisis de EAEs indica dos direcciones preferentes de la deformación (o movimiento preferente del terreno): NNO-SSE y ENEOSO. Aunque los datos presentan una dispersión importante, se puede establecer que la orientación principal NNO-SSE es compatible con un evento sísmico situado en el borde norte del Valle del Guadalquivir. La orientación ENE-OSO podría relacionarse con un evento posterior, o más seguramente con procesos de ladera de carácter cosísmico o no.The Roman archaeological site of Mulva-Munigua (Sevilla, Spain) displays building damage features suggesting a seismic origin (Earthquake Archaeological Effects: EAEs). The proposed seismic event could be tentatively dated in the late 3rd century AD, coinciding with the beginning of the economic fall of the Roman Empire at Iberia. However, some of the recorded EAEs can be also interpreted as a result of intervening slope movements in the eastern hillslope of this roman site. The inventory and analysis of the proposed EAEs make possible to discern between seismic oriented damage and other causes. In spite of the data show a significant dispersion, their analysis result in two different orientations of maximum deformation (ey) or preferential ground movement: NNW-SSE and ENE-WSW. The main ey orientation (NNW-SSE) can be tentatively related to a seismic event occurred in the environs of the northern border of the Guadalquivir Depression. The secondary orientation (ENE-WSW) can be interpreted as a consequence of latter slope movements triggered (or not) by other ancient earthquakes

    High Protein Binding and Cidal Activity against Penicillin-Resistant S. pneumoniae: A Cefditoren In Vitro Pharmacodynamic Simulation

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    BACKGROUND: Although protein binding is a reversible phenomenon, it is assumed that antibacterial activity is exclusively exerted by the free (unbound) fraction of antibiotics. METHODOLOGY/PRINCIPAL FINDINGS: Activity of cefditoren, a highly protein bound 3(rd) generation cephalosporin, over 24h after an oral 400 mg cefditoren-pivoxil bid regimen was studied against six S. pneumoniae strains (penicillin/cefditoren MICs; microg/ml): S1 (0.12/0.25), S2 (0.25/0.25), S3 and S4 (0.5/0.5), S5 (1/0.5) and S6 (4/0.5). A computerized pharmacodynamic simulation with media consisting in 75% human serum and 25% broth (mean albumin concentrations = 4.85+/-0.12 g/dL) was performed. Protein binding was measured. The cumulative percentage of a 24h-period that drug concentrations exceeded the MIC for total (T > MIC) and unbound concentrations (fT > MIC), expressed as percentage of the dosing interval, were determined. Protein binding was 87.1%. Bactericidal activity (> or = 99.9% initial inocula reduction) was obtained against strains S1 and S2 at 24h (T > MIC = 77.6%, fT > MIC = 23.7%). With T > MIC of 61.6% (fT > MIC = 1.7%), reductions against S3 and S4 ranged from 90% to 97% at 12h and 24h; against S5, reduction was 45.1% at 12h and up to 85.0% at 24h; and against S6, reduction was 91.8% at 12h, but due to regrowth of 52.9% at 24h. Cefditoren physiological concentrations exerted antibacterial activity against strains exhibiting MICs of 0.25 and 0.5 microg/ml under protein binding conditions similar to those in humans. CONCLUSIONS/SIGNIFICANCE: The results of this study suggest that, from the pharmacodynamic perspective, the presence of physiological albumin concentrations may not preclude antipneumococcal activity of highly bound cephalosporins as cefditoren

    Enhanced recovery in colorectal surgery: a multicentre study

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    <p>Abstract</p> <p>Background</p> <p>Major colorectal surgery usually requires a hospital stay of more than 12 days. Inadequate pain management, intestinal dysfunction and immobilisation are the main factors associated with delay in recovery. The present work assesses the short and medium term results achieved by an enhanced recovery program based on previously published protocols.</p> <p>Methods</p> <p>This prospective study, performed at 12 Spanish hospitals in 2008 and 2009, involved 300 patients. All patients underwent elective colorectal resection for cancer following an enhanced recovery program. The main elements of this program were: preoperative advice, no colon preparation, provision of carbohydrate-rich drinks one day prior and on the morning of surgery, goal directed fluid administration, body temperature control during surgery, avoiding drainages and nasogastric tubes, early mobilisation, and the taking of oral fluids in the early postoperative period. Perioperative morbidity and mortality data were collected and the length of hospital stay and protocol compliance recorded.</p> <p>Results</p> <p>The median age of the patients was 68 years. Fifty-two % of the patients were women. The distribution of patients by ASA class was: I 10%, II 50% and III 40%. Sixty-four % of interventions were laparoscopic; 15% required conversion to laparotomy. The majority of patients underwent sigmoidectomy or right hemicolectomy. The overall compliance to protocol was approximately 65%, but varied widely in its different components. The median length of postoperative hospital stay was 6 days. Some 3% of patients were readmitted to hospital after discharge; some 7% required repeat surgery during their initial hospitalisation or after readmission. The most common complications were surgical (24%), followed by septic (11%) or other medical complications (10%). Three patients (1%) died during follow-up. Some 31% of patients suffered symptoms that delayed their discharge, the most common being vomiting or nausea (12%), dyspnoea (7%) and fever (5%).</p> <p>Conclusion</p> <p>The following of this enhanced recovery program posed no risk to patients in terms of morbidity, mortality and shortened the length of their hospital stay. Overall compliance to protocol was 65%. The following of this program was of benefit to patients and reduces costs by shortening the length of hospital stay. The implantation of such programmes is therefore highly recommended.</p

    Proteomic analysis of low-grade, early-stage endometrial carcinoma reveals new dysregulated pathways associated with cell death and cell signaling

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    Low-grade, early-stage endometrial carcinoma (EC) is the most frequent malignant tumor of the uterine corpus. However, the molecular alterations that underlie these tumors are far from being fully understood. The purpose of this study is to describe dysregulated molecular pathways from EC patients. Sixteen samples of tumor tissue and paired healthy controls were collected and both were subjected to mass spectrometry (MS)/MS proteomic analysis. Gene ontology and pathway analysis was performed to discover dysregulated pathways and/or proteins using different databases and bioinformatic tools. Dysregulated pathways were cross-validated in an independent external cohort. Cell signaling, immune response, and cell death-associated pathways were robustly identified. The SLIT/ROBO signaling pathway demonstrated dysregulation at the proteomic and transcriptomic level. Necroptosis and ferroptosis were cell death-associated processes aberrantly regulated, in addition to apoptosis. Immune response-associated pathways showed a dominance of innate immune responses. Tumor immune infiltrates measured by immunofluorescence demonstrated diverse lymphoid and myeloid populations. Our results suggest a role of SLIT/ROBO, necroptosis, and ferroptosis, as well as a prominent role of innate immune response in low-grade, early-stage EC. These results could guide future research in this group of tumorsThis research was funded by the Instituto de Salud Carlos III (ISCIII) (PI17/01723), cofinanced by the European Development Regional Fund “A way to achieve Europe” (FEDER

    El complejo eólico de El Abalario (Huelva)

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    El área de El Abalario (Huelva) situada en la cuenca Neógena del Guadalquivir e incluida en parte dentro del Parque Natural de Doñana (Fig.1), constituye el sector litoral con el mayor y “más completo” registro de materiales eólicos aflorantes desarrollados desde el Pleistoceno Superior hasta la actualidad en la Península Ibérica. Numerosos trabajos han sido publicados desde los años setenta cuando Caratini y Viguier (1973) consideraron todos los depósitos aflorantes a lo largo del acantilado de El Asperillo (sector costero de El Abalario) como sedimentos eólicos de edad Holocena, en base a datos polínicos. Posteriormente, Zazo et al. (1981) distinguen próximos a la Torre del Loro, sedimentos fluviales y marinos en la base del acantilado y realizan las primeras dataciones de radiocarbono en los sedimentos fluviales. El estudio geomorfológico junto con la interpretación de numerosos sondeos llevados a cabo por el IGME en el área del Abalario llevan a Goy et al. (1994) a considerar esta área como una zona inestable sometida a una tectónica activa durante el Cuaternario.Este trabajo ha sido financiado por los Proyectos CGL2008-04000, CGL2008-3998, OAPN-036/2008 y GRACCIE-CSD-2007-00067. Es una contribución al IGCP495 (Quaternary Land Ocean Interactions: Driving Mechanisms and Coastal Responses); al Proyecto 0911-INQUA-CMP (Decoding the Last Interglacial in Western Mediterranean) y al Grupo de Trabajo de la UCM- 910198.Peer reviewe

    Paleogeografía y Paleosismicidad: El caso de estudio Bajo Segura, SE España

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    Trabajo presentado en la XIV Reunión Nacional de Cuaternario, celebrada en Granada (España), del 30 de junio al 2 de julio de 2015El presente trabajo aborda el análisis paleogeográfico de la Depresión del Bajo Segura donde se ubicaba la antigua bahía Ibero-Romana del Sinus ilicitanus. Se confrontan datos de reconstrucciones paleogeográficas, documentos históricos con el análisis geomorfológico del sistema de acequias, azudes y canales de la zona y su desarrollo en diferentes periodos. Se concluye que durante la época musulmana la zona afectada por el terremoto en las inmediaciones de Orihuela era un sistema deltáico palmeado 1048 AD se relacionan con fracturación del terreno y procesos de licuefacción, así como un relevante cambio del curso del rí Segura y abandono del sistema deltaico.This work has been funded by the Spanish research projects CGL2012 (QTECTBETICA -USAL), CGL2012-33430 (CSIC) and CGL2013-42847-R (UNED) and W. G. QTECT-AEQUAPeer reviewe

    Los terremotos antiguos del conjunto arqueológico romano de Baelo Claudia (Cádiz, Sur de España): Quince años de investigación arqueosismológica

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    El presente trabajo ilustra el estado del conocimiento sobre arqueosismología en la antigua ciudad romana de Baelo Claudia (Tarifa, Cádiz) tras casi quince años de investigaciones. Esta antigua ciudad romana se vio afectada por dos importantes terremotos en los años 40–60 AD y 260–290 AD. El primero de ellos afectó en mayor grado a la parte baja (costera) de la ciudad provocando importantes cambios urbanísticos y arquitectónicos (monumentalización) en respuesta a las labores de reconstrucción. El segundo de ellos provocó una mayor destrucción, cuya ruina progresiva desembocó en el abandono definitivo de la ciudad en el 365–390 AD. Se catalogan, cartografían y describen la mayor parte de los Efectos Arqueológicos de los Terremotos (EAEs) del sector monumental de la ciudad, que testifican los efectos producidos por el terremoto ocurrido en el 260–90 AD. La cartografía de daños (EAEs) muestra la distribución y orientación de los daños en la zona baja de la ciudad, así como la ocurrencia de otros procesos cosísmicos, como deslizamientos y pequeños tsunamis. El análisis estructural del conjunto de daños orientados indica que la dirección de movimiento del terreno se produjo en una dirección dominante del SO al NE. Los análisis geoarqueológicos, así como importantes anomalías constructivas y funerarias, sugieren la intervención de tsunamis de escaso poder de penetración durante los dos terremotos, apuntando a la existencia de una fuente sísmica submarina común al SSO de la ciudad. Se han identificado diferentes fallas normales de dirección N-S en la zona de la Bahía de Bolonia, algunas de las cuales se prolongan hacia el interior del mar en la zona SSO de Baelo Claudia. Estas fallas presentan claras evidencias de actividad Cuaternaria y podrían considerarse como las fuentes sísmicas más probables para los dos antiguos terremotos que afectaron a la ciudad en época romana.Departamento de Geología, Escuela Politécnica Superior de Ávila, Universidad Salamanca, EspañaDepartamento de Geología y Geoquímica, Universidad Autónoma de Madrid, EspañaInstitut für Neotektonik und Naturgefahren, Universität Aachen, AlemaniaÁrea de Riesgos Naturales, Instituto Geológico y Minero de España, EspañaDepartment of Earth Sciences, University of Cambridge, Reino UnidoConjunto Arqueológico Romano de Baelo Claudia, Junta de Andalucía, EspañaDepartamento de Ingeniería del Terreno, Escuela Politécnica Superior de Ávila, Universidad de Salamanca, EspañaU.D. Geología, Universidad de Alcalá, EspañaDepartamento de Edafología, Universidad Politécnica de Madrid, EspañaDepartamento de Geología, Universidad de Salamanca, EspañaDepartamento de Geología, Museo Nacional de Ciencias Naturales, Españ
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