A new gravitational N-body simulation algorithm for investigation of cosmological chaotic advection

Recently alternative approaches in cosmology seeks to explain the nature of dark matter as a direct result of the non-linear spacetime curvature due to different types of deformation potentials. In this context, a key test for this hypothesis is to examine the effects of deformation on the evolution of large scales structures. An important requirement for the fine analysis of this pure gravitational signature (without dark matter elements) is to characterize the position of a galaxy during its trajectory to the gravitational collapse of super clusters at low redshifts. In this context, each element in an gravitational N-body simulation behaves as a tracer of collapse governed by the process known as chaotic advection (or lagrangian turbulence). In order to develop a detailed study of this new approach we develop the COsmic LAgrangian TUrbulence Simulator (COLATUS) to perform gravitational N-body simulations based on Compute Unified Device Architecture (CUDA) for graphics processing units (GPUs). In this paper we report the first robust results obtained from COLATUS.Comment: Proceedings of Sixth International School on Field Theory and Gravitation-2012 - by American Institute of Physic

Pancreas glucagon immunolocalization in the scorpion mud turtle, kinosternon scorpioides Running title: pancreas glucagon immunolocalization in turtle

Jurará (Kinosternon scorpioides) is a semi-aquatic fresh water turtle. It is a species of the Brazilian fauna in imminent risk of extinction. Thus studies have been carried out to develop its rearing in captivity. In the present study pancreas fragments were used from six adult K. Scorpioides specimens (three males and three females) blocked in paraffin. Semi-seried3?m thick cuts were obtained in a rotating microtome and fixed on previously treated histological slides (sylanized). The pancreas cuts were submitted to the streptavidin-peroxidase technique to detect glucagon antigens present in the pancreas parenchyma of jurará. Quantitative analysis of the slides was made by counting 20 distinct fields containing glucagon immunoreactive cells under an optical microscope with a 40X objective lens. Glucagon immunoreactive cells were identified in the pancreas parenchymaof the mud turtle, and they were more frequent in the pancreatic islets. They were also observed in the exocrine parenchyma and in the epithelial of the pancreatic duct cover. Histological analysis showed that the pancreatic is lets did not present a capsule of conjunctive tissue. Quantitative analysis showed glucagon immunoreactive cells per field an average of cells 21.4 ± 11.4. Glucagon immmunoreactive cells were observed throughout the organ. 

Pancreas glucagon immunolocalization in the scorpion mud turtle, kinosternon scorpioides Running title: pancreas glucagon immunolocalization in turtle

Jurará (Kinosternon scorpioides) is a semi-aquatic fresh water turtle. It is a species of the Brazilian fauna in imminent risk of extinction. Thus studies have been carried out to develop its rearing in captivity. In the present study pancreas fragments were used from six adult K. Scorpioides specimens (three males and three females) blocked in paraffin. Semi-seried3μm thick cuts were obtained in a rotating microtome and fixed on previously treated histological slides (sylanized). The pancreas cuts were submitted to the streptavidin-peroxidase technique to detect glucagon antigens present in the pancreas parenchyma of jurará. Quantitative analysis of the slides was made by counting 20 distinct fields containing glucagon immunoreactive cells under an optical microscope with a 40X objective lens. Glucagon immunoreactive cells were identified in the pancreas parenchymaof the mud turtle, and they were more frequent in the pancreatic islets. They were also observed in the exocrine parenchyma and in the epithelial of the pancreatic duct cover. Histological analysis showed that the pancreatic is lets did not present a capsule of conjunctive tissue. Quantitative analysis showed glucagon immunoreactive cells per field an average of cells 21.4 ± 11.4. Glucagon immmunoreactive cells were observed throughout the organ. 

Renal Fornix Rupture Due To Acute Ureteral Obstruction

Background: Renal fornix rupture with fluid extravasation is a rare complication in cases of ureteral obstruction, which is usually caused by obstructive ureterolithiasis. The symptoms of renal fornix rupture are not very specific and can easily go unnoticed due to their underlying cause. Case representation: The present article reports a case of a patient of a 70-year-old, male, who was diagnosed with a ruptured renal fornix due to acute ureteral obstruction, following clinical assessment and a non-contrast CT scan. The proposed course of action was the endoscopic placement of a double J ureteral catheter. Conclusion: In the case described, the conservative treatment that was chosen by passing a double J catheter through the left ureter, for the patient proved to be an alternative to surgical treatment in the acute event, reducing the risk of possible complications from the operation. It was possible to conclude that although renal fornix rupture is a rare emergency with multiple etiologies, conservative treatment with urinary diversion using a double J ureteral stent was effective in solving the patient\u27s acute condition

Aerobic capacity of wistar rats: the effects of training and physical detraining at middle-aged

It has been shown that engaging in regular physical exercise yields short- and long-term health benefits, primarily by mitigating the risk for cardiovascular disease, but little information is known about physical deconditioning at aging process. The aim of the present study was to analyze the aerobic capacity, through maximal lactate steady state (MLSS), in Wistar rats of different ages (2,4, 6 e 12 months ) and physical conditioning deconditioning responses in middle-aged rats. The results were significant for weight gain in the sedentary (588 ± 71 g) and detraining animals (576 ± 62 g) at 12 months, whereas the conditioned group maintained their original body weights – BW (515 ± 72 g), similar at four (455 ±17 g) and six months of age (471 ± 37 g). MLSS decreased with age (2 months sedentary (8.4 ± 1% Body Weight, 4 months sedentary (6.4 ± 0.6% BW), 6 months sedentary (5.8 ± 1% BW), 12 months sedentary (5.1 ± 0.7% BW), but physical exercise was effective in attenuating the age-related loss of aerobic capacity after 12 months (5.8 ± 1.3% BW). The physical detraining was (5.3 ± 0.4% BW) was similar at 12 months trained. The physical training in long term protected against the increased of the body weight and fat depots caused by aging, but, this effect was found by deconditioning physical. Additionally, the physical training attenuated the aerobic capacity loss due to aging process and this effect was maintained after detraining physical.Tem sido demonstrado que o engajamento em exercícios físicos regulares gera benefícios para a saúde a curto e a longo prazo, principalmente a redução do risco de doença cardiovascular, mas pouco se sabe sobre o destreinamento físico no processo de envelhecimento. O objetivo do presente estudo foi analisar a capacidade aeróbia, através da máxima fase estável de lactato (MFEL), em ratos Wistar de diferentes idades e em resposta ao treinamento e ao destreinamento físico em ratos de meia-idade. Os resultados foram significativos para o ganho de peso corporal no grupo sedentário (588 ± 71 g) e animais destreinados com 12 meses (576 ± 62 g), enquanto o grupo treinado manteve o peso corpo semelhante aosanimais – PC (515 ± 72 g), do grupo de quatro meses (455 ± 17 g) e seis meses de idade (471 ± 37 g). Como medida da capacidade aeróbia, a MFEL diminuiu com a idade (2 meses sedentários (8,4 ± 1% PC), 4 meses sedentários (6,4 ± 0,6% PC), 6 meses sedentários (5,8 ± 1% PC), 12 meses sedentários (5.1 ± 0,7% PC), mas o exercício físico foi eficaz em atenuar a perda da capacidade aeróbia relacionada com a idade, o grupo 12 meses treinados (5,8 ± 1,3% PC) e o grupo destreinado (5,3 ± 0,4% PC) tiveram resultados semelhante na capacidade aeróbia. O treinamento físico de longo prazo protege contra o aumento do peso corporal e o aumento de depósitos de gordura causada pelo envelhecimento. Porém, este efeito foi abolido pelo destreinametno físico. Além disso, o treinamento físico preveniu a diminuição da capacidade aeróbia, devido ao processo de envelhecimento e este efeito foi mantido após destreinamento físico

COMPARAÇÃO DE TESTES BIOQUÍMICOS NO DIAGNÓSTICO E MONITORAMENTO DO DIABETES MELLITUS TIPO 1 EM ADOLESCENTES VULNERÁVEIS SOCIOECONOMICAMENTE: UMA REVISÃO DA LITERATURA

A natureza crônica, a gravidade das complicações e os meios necessários para o controle do DM1 a tornam onerosa para os indivíduos afetados, suas famílias e para o sistema de saúde, fazendo com que os custos de tratamento e monitorização de equipamento combinado com as necessidades diárias de um adolescente com DM1, possam representar um fardo financeiro significativo sobre toda a família. A renda per capita mensal predominante da família deste grupo é de entorno meio salário mínimo. A maior parcela de indivíduos que englobam esta renda apresenta inadequações metabólicas e outras consequências, trazendo gastos fixos e mensais, dentre estes gastos, destacam-se os testes laboratoriais. Neste contexto, este estudo visa comparar quais são os testes laboratoriais bioquímicos mais efetivos para o diagnóstico e monitoramento do DM1 em jovens socioeconomicamente vulneráveis, considerando as variáveis: preço, rapidez e custo-benefício. O desenho metodológico consistiu em uma revisão de literatura delimitada em artigos científicos no período de 10 anos, com início em 2009 e término em 2019. Foram selecionados os 10 testes bioquímicos mais utilizados no diagnóstico e monitoramento do tratamento do DM1, com base no preço, rapidez/método e custo-benefício, mediante a literatura consultada. Com os testes bioquímicos identificados verificou-se que é possível viabilizar e dinamizar o acesso e tratamento do paciente na assistência e cuidados em saúde, com uma resposta rápida e assertiva ao diagnóstico e monitoramento do seu tratamento. Os achados desta pesquisa possibilitam gerar um novo posicionamento por parte do Estado, somando às novas expectativas de alta resolubilidade proporcionada por este estudo, para então chamar atenção das autoridades em saúde

Natural Breeding Places for Phlebotomine Sand Flies (Diptera: Psychodidae) in a Semiarid Region of Bahia State, Brazil

Few microhabitats have been previously identified as natural breeding places for phlebotomine sand flies so far, and little is known about the influence of climate variables in their density. The present study was conducted in a dry region with a semiarid climate, where visceral leishmaniasis occurs in humans and dogs. The occurrence of breeding places in specific microhabitats was investigated in soil samples collected from five houses, which were also the location used for sampling of adults. All the microhabitats sampled by our study were identified as natural breeding places due to the occurrence of immature forms of sand flies. On a weekly basis, the number of adult sand flies captured was positively correlated with the mean temperature from preceding weeks. These results, in addition to promoting an advance in the knowledge of sand flies biology, may furnish a tool for optimizing the control of the sand flies, by indicating the most suitable periods and microhabitats for the application of insecticides

Manual resistance training: alternative form to increase strength in postmenopausal women after interruption of traditional resistance training

Objetivos: O objetivo do estudo foi verificar o efeito do treinamento resistido manual (TRM) sobre a força muscular de mulheres pós-menopáusicas após interrupção de um programa de treinamento resistido tradicional na musculação. Métodos: A amostra contou com 8 mulheres saudáveis (60,0+7,1 anos), pós-menopáusicas, e que vinham mantendo rotina de treinamento resistido tradicional por, pelo menos, 6 meses antecedentes ao estudo. Todas as voluntárias foram submetidas a testes de repetições máximas para estimativa de 1RM nos exercícios supino reto com barra e leg press horizontal nos momentos pré e pós-intervenção. O programa de treinamento foi composto por 9 exercícios, 3 séries de 15 repetições máximas com 1 minuto de intervalo entres as séries. Os treinos foram realizados 3 vezes por semana, durante 12 semanas. Resultados: Os resultados mostraram aumento significativo na força nos exercícios supino reto com barra (12,8%) e leg press horizontal (15,6%). Conclusão: Conclui-se que um programa de TRM de 12 semanas foi eficiente em aumentar a força muscular de mulheres pós-menopausicas, após interrupção de programa de treinamento resistido tradicional na musculação. Esses achados sugerem que o TRM pode ser uma alternativa para situações nas quais a continuidade do programa de treinamento resistido tradicional não seja possível.Objective: The aim of the study was to investigate the effect of manual resistance training (MRT) on muscle strength postmenopausal women. Methods: Eight healthy postmenopausal women (60.0 +7.1 years) and who had been keeping traditional strength training programs for at least 6 months. All participants were evaluated by tests of maximal repetitions to estimate the 1RM barbell bench press and horizontal leg press in pre and post-training. The training program has 9 exercises, 3 sets of 15 maximal repetitions with 1 minute rest interval. The bouts had a frequency of three time for week, during 12 weeks. Results: The results showed significant increase in strength in barbell bench press (12.8%) and horizontal leg press (15.6 %). Conclusion: It is concluded that 12 weeks of MRT program was effective in increasing muscle strength of women coming maintaining a program of strength training for at least 6 months. These findings suggest that the MRT can be an alternative for situations in which the continuity of the traditional strength training program is interrupted

A importância da composição da massa asfáltica para um bom desempenho

O presente artigo aborda os tipos de composição asfáltica existentes e a resistência que possuem em estradas de grande movimentação. O que define a resistência de uma massa asfáltica é a qualidade de materiais empregados bem como a quantidade de todos os materiais utilizados aliados a técnicas desenvolvidas por engenheiros especializados no assunto. O asfalto tem sido o principal material cimentante utilizado na construção de rodovias e vias urbanas. Entretanto, os aumentos do número de veículos comerciais e da carga transportada por eixo, entre outros fatores, contribuem para a ruptura prematura dos pavimentos, resultando em aumento dos custos de manutenção, engarrafamentos e atrasos aos usuários. O aumento do interesse pelo desenvolvimento de materiais mais resistentes para os pavimentos rodoviários se insere no contexto da melhoria das condições das vias a partir da diminuição dos defeitos funcionais e estruturais. As deformações permanentes podem ser decorrentes das solicitações de cargas elevadas associadas a elevadas temperaturas, enquanto o alto grau de trincamento pode decorrer da fadiga dos revestimentos quando não são utilizados materiais, dosagens e projetos adequados. O transporte viário de cargas é de grande volume diário e a pavimentação malfeita com materiais de qualidade ruins aliados a uma crise de responsabilidade política em nosso país, faz com que o asfalto mal feito gere transtornos gravíssimos como acidentes e retrabalho para o setor de Obras do DNER