Redefining Religious Truth as a Challenge for Philosophy of Religion

One of the most important features of contemporary Western societies is the rise of pluralism. Whereas theism used to serve as a common ground to discuss the truth-claims of religion, this approach seems to have lost much of its plausibility. What I want to argue in this article is that philosophy of religion as a critical intellectual activity still cannot do without the notion of religious truth, but also that it needs to redefine this truth in an existential way, i.e. by interpreting religions as concrete ways of life. In this paper I develop this idea of religious truth by interpreting religions as traditions of wisdom, being a kind of truth that is able to orientate humans’ lives without being swayed by the issues of the day. In order to substantiate my interpretation I discuss three fundamental aspects of wisdom, viz. the fact that it rests on a broadened idea of reason, the way in which it discovers the universal in the particular, and the insight that all life-orientations are based on a principle that is subjectively adequate, but objectively inadequate

Living as if God exists: Looking for Common Ground in Times of Radical Pluralism

This paper offers some comments on some metaphysical and epistemological claims of theological realism from the perspective of continental philosophy of religion, thereby taking the work of Soskice and Hick as paradigmatic for this kind of philosophical theology. The first comment regards the fact that theological realism considers religious and theological propositions as ways to depict or represent reality, and hence aims to bring them as much as possible in line with scientific ones. Some contemporary French philosophers criticize such a representing, depicting knowledge of God, because it encapsulates the divine reality in mundane, specifically scientific categories. eventually, theological realism runs the risk of annihilating God’s radical transcendence and reducing religion to an alternative scientific theory. The second comment tries to explore whether one can affirm God’s reality from a practical perspective, as a postulate of reason, and whether such an approach could serve as a common ground for religious and secular ways of life in times of radical pluralism. This comment begins by investigating the regulative character of Kant’s idea of God as the highest idea of reason, which not only orientates our theoretical enquiries, but also our moral actions. Although this idea is only a heuristic fiction for theoretical reason, God’s existence has to be affirmed on practical grounds, as a symbolic reality that gives orientation to people’s lives

Alcohol, assault and licensed premises in inner-city areas

This report contains eight linked feasibility studies conducted in Cairns during 2010. These exploratory studies examine the complex challenges of compiling and sharing information about incidents of person-to-person violence in a late night entertainment precinct (LNEP). The challenges were methodological as well as logistical and ethical. The studies look at how information can be usefully shared, while preserving the confidentiality of those involved. They also examine how information can be compiled from routinely collected sources with little or no additional resources, and then shared by the agencies that are providing and using the information.Although the studies are linked, they are also stand-alone and so can be published in peer-reviewed literature. Some have already been published, or are ‘in press’ or have been submitted for review. Others require the NDLERF board’s permission to be published as they include data related more directly to policing, or they include information provided by police.The studies are incorporated into the document under section headings. In each section, they are introduced and then presented in their final draft form. The final published form of each paper, however, is likely to be different from the draft because of journal and reviewer requirements. The content, results and implications of each study are discussed in summaries included in each section.Funded by the National Drug Law Enforcement Research Fund, an initiative of the National Drug StrategyAlan R Clough (PhD) School of Public Health, Tropical Medicine and Rehabilitation Sciences James Cook UniversityCharmaine S Hayes-Jonkers (BPsy, BSocSci (Hon1)) James Cook University, Cairns.Edward S Pointing (BPsych) James Cook University, Cairns

X chromosome inactivation: Activation of Silencing

X chromosome inactivation is a process that ensures equal expression of the X chromosomes between males, which have one X and one Y chromosome, and females, which have two X chromosomes, in mammals. Females initiate inactivation of one of their two X chromosomes early during embryogenesis, by expressing an untranslated RNA from the X-encoded Xist gene. Xist RNA coats and silences the X chromosome in cis, after which the silenced state of the inactive X chromosome is propagated through many cell divisions. Three major research questions dominate the field of XCI. How is a cell able to count the number of X chromosomes present? How is it possible that only one of the two X chromosomes in female diploid cells is inactivated? And how is the X chromosome silenced in cis? Although many researchers have attempted to explain the initiation and regulation of the XCI process with a wide array of models, none of the proposed models is able to explain all observations made with deletion and overexpression studies in mouse ES cell lines and embryos. Therefore, the aim of this thesis is to obtain additional data, and to postulate a comprehensive model for the initiation of XCI in the mouse. This model will encompass how the cell is able to detect the number of X chromosomes and how it can inactivate only one of them without inactivating all X chromosomes present in a cell. The discovery of an important activator of XCI initiation strengthens this model. Furthermore, the mechanism of spreading of Xist RNA, and thus the silencing of the X chromosome in cis, will be addressed. A hypothesis regarding the spreading of Xist RNA over the inactive X, and how Xist RNA is restricted to the Xi, will be formulated. Overall, the most important conundrums in XCI will be addressed in this thesis, and we present a more logical and complete model explaining the regulation of XCI

Research Performance Based Funding Systems: a Comparative Assessment

Performance based funding is used by most EU Member States to increase the performance of their public research system. This report analyses the different nature of systems in EU Member States, selected associated and third countries. It aims to inform Member States which are in a process of mutual learning to improve the design of their allocation systems. • Research Performance based funding systems provide incentives to increase scientific performance and concentrates resources in well performing organisations • The nature of systems in place differs widely • The specific features of RPBF assessment designs can generate unintended consequences • The assessment suggests RPBF as a potential avenue for several Member States • The choice for specific designs, taking into accounts costs and potential benefits, should take into account the national contextJRC.J.6-Innovation Systems Analysi

Subchondral bone density distribution of the canine talus

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A goal-oriented requirements modelling language for enterprise architecture

Methods for enterprise architecture, such as TOGAF, acknowledge the importance of requirements engineering in the development of enterprise architectures. Modelling support is needed to specify, document, communicate and reason about goals and requirements. Current modelling techniques for enterprise architecture focus on the products, services, processes and applications of an enterprise. In addition, techniques may be provided to describe structured requirements lists and use cases. Little support is available however for modelling the underlying motivation of enterprise architectures in terms of stakeholder concerns and the high-level goals that address these concerns. This paper describes a language that supports the modelling of this motivation. The definition of the language is based on existing work on high-level goal and requirements modelling and is aligned with an existing standard for enterprise modelling: the ArchiMate language. Furthermore, the paper illustrates how enterprise architecture can benefit from analysis techniques in the requirements domain

The effect of a multispecies probiotic on the composition of the faecal microbiota and bowel habits in chronic obstructive pulmonary disease patients treated with antibiotics

Short-term antibiotic treatment profoundly affects the intestinal microbiota, which may lead to sustained changes in microbiota composition. Probiotics may restore such a disturbance. The objective of the present study was to investigate the effect of a multispecies probiotic on the faecal microbiota during and after antibiotic intake in patients with a history of frequent antibiotic use. In this randomised, placebo-controlled, double-blind study, thirty chronic obstructive pulmonary disease (COPD) patients treated with antibiotics for a respiratory tract infection received 5 g of a multispecies probiotic or placebo twice daily for 2 weeks. Faecal samples were collected at 0, 7, 14 and 63 d. Changes in the composition of the dominant faecal microbiota were determined by PCR-denaturing gradient gel electrophoresis (DGGE). Changes in bacterial subgroups were determined by quantitative PCR and culture. Bowel movements were scored daily according to the Bristol stool form scale. During and after antibiotic treatment, DGGE-based similarity indices (SI) were high ( >/= 84 %) and band richness was relatively low, both remaining stable over time. No difference in SI was observed between patients with and without diarrhoea-like bowel movements. The multispecies probiotic had a modest effect on the bacterial subgroups. Nevertheless, it affected neither the composition of the dominant faecal microbiota nor the occurrence of diarrhoea-like bowel movements. The dominant faecal microbiota was not affected by antibiotics in this COPD population, suggesting an existing imbalance of the microbiota, which may also have contributed to the lack of effect by probiotic intak