Longitudinal study of computerised cardiotocography in early fetal growth restriction.

OBJECTIVES: To explore if in early fetal growth restriction (FGR) the longitudinal pattern of short-term fetal heart rate (FHR) variation (STV) can be used for identifying imminent fetal distress and if abnormalities of FHR registration associate with two-year infant outcome. METHODS: The original TRUFFLE study assessed if in early FGR the use of ductus venosus Doppler pulsatility index (DVPI), in combination with a safety-net of very low STV and / or recurrent decelerations, could improve two-year infant survival without neurological impairment in comparison to computerised cardiotocography (cCTG) with STV calculation only. For this secondary analysis we selected women, who delivered before 32 weeks, and who had consecutive STV data for more than 3 days before delivery, and known infant two-year outcome data. Women who received corticosteroids within 3 days of delivery were excluded. Individual regression line algorithms of all STV values except the last one were calculated. Life table analysis and Cox regression analysis were used to calculate the day by day risk for a low STV or very low STV and / or FHR decelerations (DVPI group safety-net) and to assess which parameters were associated to this risk. Furthermore, it was assessed if STV pattern, lowest STV value or recurrent FHR decelerations were associated with two-year infant outcome. RESULTS: One hundred and fourty-nine women matched the inclusion criteria. Using the individual STV regression lines prediction of a last STV below the cCTG-group cut-off had a sensitivity of 0.42 and specificity of 0.91. For each day after inclusion the median risk for a low STV(cCTG criteria) was 4% (Interquartile range (IQR) 2% to 7%) and for a very low STV and / or recurrent decelerations (DVPI safety-net criteria) 5% (IQR 4 to 7%). Measures of STV pattern, fetal Doppler (arterial or venous), birthweight MoM or gestational age did not improve daily risk prediction usefully. There was no association of STV regression coefficients, a last low STV or /and recurrent decelerations with short or long term infant outcomes. CONCLUSION: The TRUFFLE study showed that a strategy of DVPI monitoring with a safety-net delivery indication of very low STV and / or recurrent decelerations could increase infant survival without neurological impairment at two years. This post-hoc analysis demonstrates that in early FGR the day by day risk of an abnormal cCTG as defined by the DVPI protocol safety-net criteria is 5%, and that prediction of this is not possible. This supports the rationale for cCTG monitoring more often than daily in these high-risk fetuses. Low STV and/or recurrent decelerations were not associated with adverse infant outcome and it appears safe to delay intervention until such abnormalities occur, as long as DVPI is in the normal range

The Amsterdam-St. Paul Plateau: A complex hot spot/DUPAL-flavored MORB interaction

International audienceThe Amsterdam-St Paul (ASP) oceanic plateau results from the interaction between the ASP hot spot and the Southeast Indian ridge. A volcanic chain, named the Chain of the Dead Poets (CDP), lies to its northward tip and is related to the hot spot intraplate activity. The ASP plateau and CDP study reveals that ASP plume composition is inherited from oceanic crust and pelagic sediments recycled in the mantle through a 1.5 Ga subduction process. The ASP plateau lavas have a composition (major and trace elements and Sr-Nd-Pb-Hf isotopes) reflecting the interaction between ASP plume and the Indian MORB mantle, including some clear DUPAL input. The Indian upper mantle below ASP plateau is heterogeneous and made of a depleted mantle with lower continental crust (LCC) fragments probably delaminated during the Gondwana break-up. The lower continental crust is one of the possible reservoirs for the DUPAL anomaly origin that our data support. The range of magnitude of each end-member required in ASP plateau samples is (1) 45% to 75% of ASP plume and (2) 25% to 55% of Indian DM within 0% to a maximum of 6% of LCC layers included within. The three end-members involved (plume, upper mantle and lower continental crust) and their mixing in different proportions enhances the geochemical variability in the plateau lavas. Consequently, the apparent composition homogeneity of Amsterdam Island, an aerial summit of the plateau, may result from the presence of intermediate magmatic chambers into the plateau structure

Genesis of the Western Samoa seamount province: age, geochemical fingerprint and tectonics

The Samoan volcanic lineament has many features that are consistent with a plume-driven hotspot model, including the currently active submarine volcano Vailulu'u that anchors the eastern extremity. Proximity to the northern end of the Tonga trench, and the presence of voluminous young volcanism on what should be the oldest (∼5 my) western island (Savai'i) has induced controversy regarding a simple plume/hotspot model. In an effort to further constrain this debate, we have carried out geochronological, geochemical and isotopic studies of dredge basalts from four seamounts and submarine banks that extend the Samoan lineament 1300 km further west from Savai'i. 40Ar/39Ar plateau ages from Combe and Alexa Banks (11.1 my—940 km, and 23.4 my—1690 km from Vailulu'u, respectively) fit a Pacific age progression very well. The oldest volcanism (9.8 my) on Lalla Rookh (725 km from Vailulu'u) also fits this age progression, but a new age is much younger (1.6 my). Isotopically, these three seamounts, along with Pasco Bank (590 km from Vailulu'u), all lie within, or closely along extensions of, the Sr–Nd–Pb fields for shield basalts from the Eastern Samoan Province (Savai'i to Vailulu'u); this clearly establishes a Samoan pedigree for this western extension of the Samoan hotspot chain, and pushes the inception of Samoan volcanism back to at least 23 my. From geodetic reconstructions of the Fiji–Tonga–Samoa region, we show that the northern terminus of the Tonga arc was too far west of the Samoa hotspot up until 1–2 my ago to have been a factor in its volcanism. Young rejuvenated volcanism on Lalla Rookh and Savai'i may be related to the rapid eastward encroachment of the Trench corner. The Vitiaz Lineament, previously thought to mark a proto-Tongan subduction zone, was more likely created by the eastward propagation of the tear in the Pacific Plate at the northern end of the arc

Drilling constraints on lithospheric accretion and evolution at Atlantis Massif, Mid-Atlantic Ridge 30°N

Expeditions 304 and 305 of the Integrated Ocean Drilling Program cored and logged a 1.4 km section of the domal core of Atlantis Massif. Postdrilling research results summarized here constrain the structure and lithology of the Central Dome of this oceanic core complex. The dominantly gabbroic sequence recovered contrasts with predrilling predictions; application of the ground truth in subsequent geophysical processing has produced self-consistent models for the Central Dome. The presence of many thin interfingered petrologic units indicates that the intrusions forming the domal core were emplaced over a minimum of 100–220 kyr, and not as a single magma pulse. Isotopic and mineralogical alteration is intense in the upper 100 m but decreases in intensity with depth. Below 800 m, alteration is restricted to narrow zones surrounding faults, veins, igneous contacts, and to an interval of locally intense serpentinization in olivine-rich troctolite. Hydration of the lithosphere occurred over the complete range of temperature conditions from granulite to zeolite facies, but was predominantly in the amphibolite and greenschist range. Deformation of the sequence was remarkably localized, despite paleomagnetic indications that the dome has undergone at least 45° rotation, presumably during unroofing via detachment faulting. Both the deformation pattern and the lithology contrast with what is known from seafloor studies on the adjacent Southern Ridge of the massif. There, the detachment capping the domal core deformed a 100 m thick zone and serpentinized peridotite comprises ∼70% of recovered samples. We develop a working model of the evolution of Atlantis Massif over the past 2 Myr, outlining several stages that could explain the observed similarities and differences between the Central Dome and the Southern Ridge

Oceanic core complexes and crustal accretion at slow-spreading ridges

Oceanic core complexes expose gabbroic rocks on the seafloor via detachment faulting, often associated with serpentinized peridotite. The thickness of these serpentinite units is unknown. Assuming that the steep slopes that typically surround these core complexes provide a cross section through the structure, it has been inferred that serpentinites compose much of the section to depths of at least several hundred meters. However, deep drilling at oceanic core complexes has recovered gabbroic sequences with virtually no serpentinized peridotite. We propose a revised model for oceanic core complex development based on consideration of the rheological differences between gabbro and serpentinized peridotite: emplacement of a large intrusive gabbro body into a predominantly peridotite host is followed by localization of strain around the margins of the pluton, eventually resulting in an uplifted gabbroic core surrounded by deformed serpentinite. Oceanic core complexes may therefore reflect processes associated with relatively enhanced periods of mafic intrusion within overall magma-poor regions of slow- and ultra-slow-spreading ridges

Drilling constraints on lithospheric accretion and evolution at Atlantis Massif, Mid-Atlantic Ridge 30N

Expeditions 304 and 305 of the Integrated Ocean Drilling Program cored and logged a 1.4 km section of the domal core of Atlantis Massif. Postdrilling research results summarized here constrain the structure and lithology of the Central Dome of this oceanic core complex. The dominantly gabbroic sequence recovered contrasts with predrilling predictions; application of the ground truth in subsequent geophysical processing has produced self-consistent models for the Central Dome. The presence of many thin interfingered petrologic units indicates that the intrusions forming the domal core were emplaced over a minimum of 100-220 kyr, and not as a single magma pulse. Isotopic and mineralogical alteration is intense in the upper 100 m but decreases in intensity with depth. Below 800 m, alteration is restricted to narrow zones surrounding faults, veins, igneous contacts, and to an interval of locally intense serpentinization in olivine-rich troctolite. Hydration of the lithosphere occurred over the complete range of temperature conditions from granulite to zeolite facies, but was predominantly in the amphibolite and greenschist range. Deformation of the sequence was remarkably localized, despite paleomagnetic indications that the dome has undergone at least 45 rotation, presumably during unroofing via detachment faulting. Both the deformation pattern and the lithology contrast with what is known from seafloor studies on the adjacent Southern Ridge of the massif. There, the detachment capping the domal core deformed a 100 m thick zone and serpentinized peridotite comprises ∼70% of recovered samples. We develop a working model of the evolution of Atlantis Massif over the past 2 Myr, outlining several stages that could explain the observed similarities and differences between the Central Dome and the Southern Ridge