63 research outputs found

    Interpretation of mouth-bar and related lacustrine and fluvial sand bodies from the middle Green River Formation (Eocene), southern Uinta Basin, Utah

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    Chapter for publication in From Saline to Freshwater: The Diversity of Western Lakes in Space and Time, Geological Society of America Special Publications Volume 536, DOI: https://doi.org/10.1130/SPE536. ISBN electronic: 9780813795362Peer reviewedPostprintPostprin

    The Incidence of Breast Cancer among Disabled Kansans with Medicare

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    BACKGROUND: Breast cancer disparities by disability status are poorly understood. While previous studies have shown increased odds of late stage at diagnosis, it is unclear whether the incidence of breast cancer varies by disability status. METHODS: To assess cancer incidence and stage at diagnosis among disabled and nondisabled Medicare beneficiaries in Kansas, a retrospective cohort study was conducted using linked Medicare enrollment and Kansas Cancer Registry data from 2007 to 2009. Disability status was determined by the indicator for the original reason for Medicare eligibility. RESULTS: Among the 651,337 Medicare beneficiaries included in the cohort, there were 2,384 cases of breast cancer. The age-adjusted incidence was 313 per 100,000 among female beneficiaries with disabilities and 369 per 100,000 among nondisabled female beneficiaries. The adjusted incidence rate ratio was 0.93 (95% CI 0.73-1.18). When assessing stage at diagnosis, there was no difference in the odds of late stage at diagnosis by disability status (OR = 1.02; 95% CI 0.68-1.50). CONCLUSION: No significant difference in incidence or stage at diagnosis was identified among this cohort. The use of Medicare eligibility to define disability status presented a number of limitations. Future studies should seek alternate definitions of disability to assess disparities in breast cancer incidence, including definitions using Medicare claims data

    The Mysterious Affair of the H2_2 in AU Mic

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    Molecular hydrogen is the most abundant molecule in the Galaxy and plays important roles for planets, their circumstellar environments, and many of their host stars. We have confirmed the presence of molecular hydrogen in the AU Mic system using high-resolution FUV spectra from HST-STIS during both quiescence and a flare. AU Mic is a ∌\sim23 Myr M dwarf which hosts a debris disk and at least two planets. We estimate the temperature of the gas at 1000 to 2000 K, consistent with previous detections. Based on the radial velocities and widths of the H2_2 line profiles and the response of the H2_2 lines to a stellar flare, the H2_2 line emission is likely produced in the star, rather than in the disk or the planet. However, the temperature of this gas is significantly below the temperature of the photosphere (∌\sim3650 K) and the predicted temperature of its star spots (≳\gtrsim2650 K). We discuss the possibility of colder star spots or a cold layer in the photosphere of a pre-main sequence M dwarf.Comment: accepted to ApJ, 20 pages, many figure

    Composition, Alteration, and Texture of Fault-Related Rocks from Safod Core and Surface Outcrop Analogs: Evidence for Deformation Processes and Fluid-Rock Interactions

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    We examine the fine-scale variations in mineralogical composition, geochemical alteration, and texture of the fault-related rocks from the Phase 3 whole-rock core sampled between 3,187.4 and 3,301.4 m measured depth within the San Andreas Fault Observatory at Depth (SAFOD) borehole near Parkfield, California. This work provides insight into the physical and chemical properties, structural architecture, and fluid-rock interactions associated with the actively deforming traces of the San Andreas Fault zone at depth. Exhumed outcrops within the SAF system comprised of serpentinite-bearing protolith are examined for comparison at San Simeon, Goat Rock State Park, and Nelson Creek, California. In the Phase 3 SAFOD drillcore samples, the fault-related rocks consist of multiple juxtaposed lenses of sheared, foliated siltstone and shale with block-in-matrix fabric, black cataclasite to ultracataclasite, and sheared serpentinite-bearing, finely foliated fault gouge. Meters-wide zones of sheared rock and fault gouge correlate to the sites of active borehole casing deformation and are characterized by scaly clay fabric with multiple discrete slip surfaces or anastomosing shear zones that surround conglobulated or rounded clasts of compacted clay and/or serpentinite. The fine gouge matrix is composed of Mg-rich clays and serpentine minerals (saponite ± palygorskite, and lizardite ± chrysotile). Whole-rock geochemistry data show increases in Fe-, Mg-, Ni-, and Cr-oxides and hydroxides, Fe-sulfides, and C-rich material, with a total organic content of \u3e1 % locally in the fault-related rocks. The faults sampled in the field are composed of meters-thick zones of cohesive to non-cohesive, serpentinite-bearing foliated clay gouge and black fine-grained fault rock derived from sheared Franciscan Formation or serpentinized Coast Range Ophiolite. X-ray diffraction of outcrop samples shows that the foliated clay gouge is composed primarily of saponite and serpentinite, with localized increases in Ni- and Cr-oxides and C-rich material over several meters. Mesoscopic and microscopic textures and deformation mechanisms interpreted from the outcrop sites are remarkably similar to those observed in the SAFOD core. Micro-scale to meso-scale fabrics observed in the SAFOD core exhibit textural characteristics that are common in deformed serpentinites and are often attributed to aseismic deformation with episodic seismic slip. The mineralogy and whole-rock geochemistry results indicate that the fault zone experienced transient fluid–rock interactions with fluids of varying chemical composition, including evidence for highly reducing, hydrocarbon-bearing fluids

    A dual compartment cuvette system for correcting scattering in whole-cell absorbance spectroscopy of photosynthetic microorganisms.

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    Funder: Waste Environmental Education Research TrustAbsorption spectroscopy is widely used to determine absorption and transmission spectra of chromophores in solution, in addition to suspensions of particles, including micro-organisms. Light scattering, caused by photons deflected from part or all of the cells or other particles in suspension, results in distortions to the absorption spectra, lost information and poor resolution. A spectrophotometer with an integrating sphere may be used to alleviate this problem. However, these instruments are not universally available in biology laboratories, for reasons such as cost. Here, we describe a novel, rapid, and inexpensive technique that minimises the effect of light scattering when performing whole-cell spectroscopy. This method involves using a custom made dual compartment cuvette containing titanium dioxide in one chamber as a scattering agent. Measurements were conducted of a range of different photosynthetic micro-organisms of varying cell size and morphology, including cyanobacteria, eukaryotic microalgae and a purple non-sulphur bacterium. A concentration of 1 mg ml-1 titanium dioxide, using a spectrophotometer with a slit width of 5 nm, produced spectra for cyanobacteria and microalgae similar (1-4% difference) to those obtained using an integrating sphere. The spectrum > 520 nm was similar to that with an integrating sphere with the purple non-sulphur bacterium. This system produced superior results to those obtained using a recently reported method, the application of the diffusing agent, Scotchℱ Magic tape, to the side of the cuvette. The protocol can be completed in an equivalent period of time to standard whole-cell absorbance spectroscopy techniques, and is, in principle, suitable for any dual-beam spectrophotometer.Waste Environmental Education Research Trust Leverhulme Trus

    TESS hunt for young and maturing exoplanets (THYME). III. A two-planet system in the 400 Myr Ursa major group

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    A.W.M. was supported through NASA's Astrophysics Data Analysis Program (80NSSC19K0583). M.L.W. was supported by a grant through NASA's K2 GO program (80NSSC19K0097). This material is based on work supported by the National Science Foundation Graduate Research Fellowship Program under grant No. DGE-1650116 to P.C.T. A.V.'s work was performed under contract with the California Institute of Technology/Jet Propulsion Laboratory funded by NASA through the Sagan Fellowship Program executed by the NASA Exoplanet Science Institute. D.D. acknowledges support from NASA through Caltech/JPL grant RSA-1006130 and through the TESS Guest Investigator Program grant 80NSSC19K1727.Exoplanets can evolve significantly between birth and maturity, as their atmospheres, orbits, and structures are shaped by their environment. Young planets (<1 Gyr) offer an opportunity to probe the critical early stages of this evolution, where planets evolve the fastest. However, most of the known young planets orbit prohibitively faint stars. We present the discovery of two planets transiting HD 63433 (TOI 1726, TIC 130181866), a young Sun-like (M∗=0.99±0.03) star. Through kinematics, lithium abundance, and rotation, we confirm that HD 63433 is a member of the Ursa Major moving group (τ=414±23 Myr). Based on the TESS light curve and updated stellar parameters, we estimate the planet radii are 2.15±0.10R⊕ and 2.67±0.12R⊕, the orbital periods are 7.11 and 20.55 days, and the orbital eccentricities are lower than about 0.2. Using HARPS-N velocities, we measure the Rossiter-McLaughlin signal of the inner planet, demonstrating that the orbit is prograde. Since the host star is bright (V=6.9), both planets are amenable to transmission spectroscopy, radial velocity measurements of their masses, and more precise determination of the stellar obliquity. This system is therefore poised to play an important role in our understanding of planetary system evolution in the first billion years after formation.PostprintPeer reviewe
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