103 research outputs found

    CMB polarimetry with BICEP: instrument characterization, calibration, and performance

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    BICEP is a ground-based millimeter-wave bolometric array designed to target the primordial gravity wave signature on the polarization of the cosmic microwave background (CMB) at degree angular scales. Currently in its third year of operation at the South Pole, BICEP is measuring the CMB polarization with unprecedented sensitivity at 100 and 150 GHz in the cleanest available 2% of the sky, as well as deriving independent constraints on the diffuse polarized foregrounds with select observations on and off the Galactic plane. Instrument calibrations are discussed in the context of rigorous control of systematic errors, and the performance during the first two years of the experiment is reviewed.Comment: 12 pages, 15 figures, updated version of a paper accepted for Millimeter and Submillimeter Detectors and Instrumentation for Astronomy IV, Proceedings of SPIE, 7020, 200

    Absolute polarization angle calibration using polarized diffuse Galactic emission observed by BICEP

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    We present a method of cross-calibrating the polarization angle of a polarimeter using BICEP Galactic observations. \bicep\ was a ground based experiment using an array of 49 pairs of polarization sensitive bolometers observing from the geographic South Pole at 100 and 150 GHz. The BICEP polarimeter is calibrated to +/-0.01 in cross-polarization and less than +/-0.7 degrees in absolute polarization orientation. BICEP observed the temperature and polarization of the Galactic plane (R.A= 100 degrees ~ 270 degrees and Dec. = -67 degrees ~ -48 degrees). We show that the statistical error in the 100 GHz BICEP Galaxy map can constrain the polarization angle offset of WMAP Wband to 0.6 degrees +\- 1.4 degrees. The expected 1 sigma errors on the polarization angle cross-calibration for Planck or EPIC are 1.3 degrees and 0.3 degrees at 100 and 150 GHz, respectively. We also discuss the expected improvement of the BICEP Galactic field observations with forthcoming BICEP2 and Keck observations.Comment: 13 pages, 10 figures and 2 tables. To appear in Proceedings of SPIE Astronomical Telescopes and Instrumentation 201

    Scientific Verification Of Faraday Rotation Modulators: Detection Of Diffuse Polarized Galactic Emission

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    The design and performance of a wide bandwidth linear polarization modulator based on the Faraday effect is described. Faraday Rotation Modulators (FRMs) are solid-state polarization switches that are capable of modulation up to 10 kHz. Six FRMs were utilized during the 2006 observing season in the Background Imaging of Cosmic Extragalactic Polarization (BICEP) experiment; three FRMs were used at each of BICEP's 100 and 150 GHz frequency bands. The technology was verified through high signal-to-noise detection of Galactic polarization using two of the six FRMs during four observing runs in 2006. The features exhibit strong agreement with BICEP's measurements of the Galaxy using non-FRM pixels and with the Galactic polarization models. This marks the first detection of high signal-to-noise mm-wave celestial polarization using fast, active optical modulation. The performance of the FRMs during periods when they were not modulated was also analyzed and compared to results from BICEP's 43 pixels without FRMs.Astronom

    Self-calibration of BICEP1 three-year data and constraints on astrophysical polarization rotation

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    Cosmic microwave background (CMB) polarimeters aspire to measure the faint BB-mode signature predicted to arise from inflationary gravitational waves. They also have the potential to constrain cosmic birefringence, rotation of the polarization of the CMB arising from parity-violating physics, which would produce nonzero expectation values for the CMB’s temperature to BB-mode correlation (TB)(TB) and EE-mode to BB-mode correlation (EB)(EB) spectra. However, instrumental systematic effects can also cause these TBTB and EBEB correlations to be nonzero. In particular, an overall miscalibration of the polarization orientation of the detectors produces TBTB and EBEB spectra which are degenerate with isotropic cosmological birefringence, while also introducing a small but predictable bias on the BBBB spectrum. We find that Bicep1 three-year spectra, which use our standard calibration of detector polarization angles from a dielectric sheet, are consistent with a polarization rotation of α=−2.77∘±0.86∘\alpha = −2.77^{\circ}\pm0.86^{\circ}(statistical) ±1.3∘\pm1.3^{\circ}(systematic). We have revised the estimate of systematic error on the polarization rotation angle from the two-year analysis by comparing multiple calibration methods. We also account for the (negligible) impact of measured beam systematic effects. We investigate the polarization rotation for the Bicep1 100GHz and 150GHz bands separately to investigate theoretical models that produce frequency-dependent cosmic birefringence. We find no evidence in the data supporting either of these models or Faraday rotation of the CMB polarization by the Milky Way galaxy’s magnetic field. If we assume that there is no cosmic birefringence, we can use the TBTB and EBEB spectra to calibrate detector polarization orientations, thus reducing bias of the cosmological BB-mode spectrum from leaked E-modes due to possible polarization orientation miscalibration. After applying this “self-calibration” process, we find that the upper limit on the tensor-to-scalar ratio decreases slightly, from r<0.70r<0.70 to r<0.65r<0.65 at 95% confidence.Astronom

    Responses of Massachusetts hospitals to a state mandate to collect race, ethnicity and language data from patients: a qualitative study

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    <p>Abstract</p> <p>Background</p> <p>A Massachusetts regulation implemented in 2007 has required all acute care hospitals to report patients' race, ethnicity and preferred language using standardized methodology based on self-reported information from patients. This study assessed implementation of the regulation and its impact on the use of race and ethnicity data in performance monitoring and quality improvement within hospitals.</p> <p>Methods</p> <p>Thematic analysis of semi-structured interviews with executives from a representative sample of 28 Massachusetts hospitals in 2009.</p> <p>Results</p> <p>The number of hospitals using race, ethnicity and language data internally beyond refining interpreter services increased substantially from 11 to 21 after the regulation. Thirteen of these hospitals were utilizing patient race and ethnicity data to identify disparities in quality performance measures for a variety of clinical processes and outcomes, while 16 had developed patient services and community outreach programs based on findings from these data. Commonly reported barriers to data utilization include small numbers within categories, insufficient resources, information system requirements, and lack of direction from the state.</p> <p>Conclusions</p> <p>The responses of Massachusetts hospitals to this new state regulation indicate that requiring the collection of race, ethnicity and language data can be an effective method to promote performance monitoring and quality improvement, thereby setting the stage for federal standards and incentive programs to eliminate racial and ethnic disparities in the quality of health care.</p

    Baseline natural killer and T cell populations correlation with virologic outcome after regimen simplification to atazanavir/ritonavir alone (ACTG 5201)

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    Objectives: Simplified maintenance therapy with ritonavir-boosted atazanavir (ATV/r) provides an alternative treatment option for HIV-1 infection that spares nucleoside analogs (NRTI) for future use and decreased toxicity. We hypothesized that the level of immune activation (IA) and recovery of lymphocyte populations could influence virologic outcomes after regimen simplification. Methods: Thirty-four participants with virologic suppression ≄48 weeks on antiretroviral therapy (2 NRTI plus protease inhibitor) were switched to ATV/r alone in the context of the ACTG 5201 clinical trial. Flow cytometric analyses were performed on PBMC isolated from 25 patients with available samples, of which 24 had lymphocyte recovery sufficient for this study. Assessments included enumeration of T-cells (CD4/CD8), natural killer (NK) (CD3+CD56 +CD16+) cells and cell-associated markers (HLA-DR, CD's 38/69/94/95/158/279). Results: Eight of the 24 patients had at least one plasma HIV-1 RNA level (VL) <50 copies/mL during the study. NK cell levels below the group median of 7.1% at study entry were associated with development of VL <50 copies/mL following simplification by regression and survival analyses (p = 0.043 and 0.023), with an odds ratio of 10.3 (95% CI: 1.92-55.3). Simplification was associated with transient increases in naĂŻve and CD25+ CD4+ T-cells, and had no impact on IA levels. Conclusions: Lower NK cell levels prior to regimen simplification were predictive of virologic rebound after discontinuation of nucleoside analogs. Regimen simplification did not have a sustained impact on markers of IA or T lymphocyte populations in 48 weeks of clinical monitoring. Trial Registration: ClinicalTrials.gov NCT00084019
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