A noninferiority, prospective, randomized, controlled trial comparing embryo development using media developed for sequential or undisturbed culture in a time-lapse setup.

To study whether a culture medium that allows undisturbed culture supports human embryo development to the blastocyst stage equivalently to a well-established sequential media

The Istanbul consensus workshop on embryo assessment: Proceedings of an expert meeting

Background: Many variations in oocyte and embryo grading make inter-laboratory comparisons extremely difficult. This paper reports the proceedings of an international consensus meeting on oocyte and embryo morphology assessment. Methods: Background presentations about current practice were given. Results: The expert panel developed a set of consensus points to define the minimumcriteria for oocyte and embryomorphology assessment. Conclusions: It is expected that the definition of common terminology and standardization of laboratory practice related to embryo morphology assessment will result in more effective comparisons of treatment outcomes. This document is intended to be referenced as a global consensus to allow standardized reporting of the minimum data set required for the accurate description of embryo development