Estratégias de marketing ecológico: impacto ao nível do setor vinícola da Arménia

Mestrado em Gestão das Organizações: Ramo de Gestão de Empresas (parceria com a APNOR) na Escola Superior de Tecnologia e Gestão do Instituto Politécnico de Viana do CasteloEste trabalho pretende analisar o impacto da utilização de certificações (rótulos e outras sinaléticas) ambientais em vinhos produzidos na Arménia, ao nível da sua exportação. A revisão de literatura mostra que o marketing verde tem vantagens e desvantagens, mas os possíveis prejuízos são mínimos a favor de uma contínua melhoria de qualidade do bem ou serviço. Num estudo de caso observado na Arménia, especificamente no sector vitivinícola, analisam-se qualitativamente entrevistas efectuadas a empresas do sector vitivinícola e, com a utilização da técnica metodológica de Focus Group, a opinião de grupos com conhecimentos adquiridos da área. Verifica-se como o marketing verde é um caminho em que se pode apostar para se alcançar a internacionalização da empresa. Com efeito, para se conseguir a exportação do produto, é essencial que o país em questão implemente certificações reconhecidas internacionalmente para ser mais facilmente integrado em novos mercados. A certificação ambiental ainda não é uma exigência mundial visto que depende maioritariamente da própria legislação interna dos países. O estudo permite igualmente inferir que a utilização de uma sinalética ambiental nos rótulos das garrafas não constitui uma mais valia significativa junto dos consumidores de vinho Arménios.Este estudio tiene como objetivo examinar el impacto del uso de las certificaciones ambientales (otras etiquetas y placas de identificación) de los vinos producidos en Armenia en términos de su exportación. La revisión de la literatura muestra que el marketing verde tiene ventajas y desventajas, pero las pérdidas potenciales son mínimos en favor de una mejora continua en la calidad del bien o servicio. En un estudio de caso observados en Armenia, específicamente en el sector vitivinícola, se analizan entrevistas cualitativas con las empresas del sector del vino y, utilizando la técnica metodológica del Grupo de Foco, grupos de opinión con conocimiento de la área. Aparece como marketing verde es una forma en que pueden invertir para lograr la internacionalización de la empresa. Con efecto, para lograr un producto de exportación, es esencial que el país en cuestión implemente certificaciones reconocidas internacionalmente para que se integren más fácilmente en nuevos mercados. Certificación ambiental no es un requisito en todo el mundo, ya que depende en gran medida de la legislación propia interna de los países. El estudio nos permite inferir que el uso de una señalización ambiental en las etiquetas de las botellas no es un valor añadido significativo a los consumidores de armenios vino.This study aims to examine the impact of the use of environmental certifications (other labels and nameplates) on wines produced in Armenia in terms of their export. The literature review shows that green marketing has advantages and disadvantages, but the potential losses are minimal in favor of a continuous improvement in the quality of the good or service. In a case study observed in Armenia, specifically in the wine sector, it’s analyzed qualitative interviews with companies of the wine sector and, by using the methodology technic of Focus Group, opinion groups with knowledge of the area. It appears as green marketing is a way to invest to achieve the internationalization of the company. To achieve product exportation it is essential that the country in question implements internationally recognized certifications to be more easily integrated into new markets. Environmental certification is not a worldwide requirement since it depends mostly on own countries domestic legislation. The study allows us to infer that the use of an environmental signage on the labels of the bottles is not a significant added value to Armenian wine consumers

A introdução dos transformados derivados de cortiça na construção portuguesa. Entre os ecos do estrangeiro e a implementação nacional.

A Cortiça esteve presente na construção desde tempos imemoriais sem nunca se estabelecer verdadeiramente como um material de construção. A partir do século XVIII, com o advento da produção e exportação vinícola, o material vê-se valorizado economicamente pela indústria das rolhas, e outras indústrias subsidiárias, que utilizam os desperdícios da primeira numa miríade de materiais transformados e de usos, nos quais, mais tardiamente, se incluirá novamente a construção.Neste artigo abordaremos o período inicial de afirmação da cortiça como material de construção a partir da análise das patentes internacionais, das referências aos novos produtos em bibliografia técnica e de divulgação nacional e de um conjunto de licenças de obra na cidade do Porto, onde se percebe que as novas utilizações decorrem do desempenho técnico (acústico e térmico) do material mas também de uma associação a uma imagem de modernidade

As novas substâncias psicoativas (NSP): discussão conceptual

New Psychoactive Substances (nps) are a relatively recent phenomenon characterized by continuous expansion throughout more or less the entire world in the last decade. They include a diversity of natural or synthetic substances that are not yet on official lists and whose great variety and rapid transformations make the nps concept itself hard to define. Methodologically combining qualitative methods in order to present a problematized systematization of national and public policies, and quantitative ones presenting the results of a survey applied to users of nps in Portugal, the paper contributes to a more precise definition of nps and their effects and to know about the evolution of the applicable legal framework.O fenómeno das Novas Substâncias Psicoativas (nsp) é relativamente recente e caracteriza-se por um crescimento contínuo na última década, um pouco por todo o mundo. Inclui-se aqui uma diversidade de substâncias naturais ou sintéticas, que não se encontram ainda enquadradas nas listagens dos organismos oficiais. A sua grande variedade e rápida transformação configuram dificuldades de delimitação conceptual. Com base numa estratégia metodológica que combina métodos qualitativos, na sistematização problematizada das políticas públicas nacionais e quantitativos, nos resultados de um questionário aplicado a consumidores portugueses destas substâncias, o artigo apresenta um contributo para a definição e evolução do enquadramento legal do fenómeno, das substâncias e dos seus efeitos.info:eu-repo/semantics/publishedVersio

Functional food components, intestinal permeability and inflammatory markers in patients with inflammatory bowel disease

Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).Inflammatory bowel diseases (IBD) are characterized by a chronic inflammatory process that affects the intestinal barrier structure. Recent evidence suggests that some food components can influence the integrity of the intestinal barrier and thus its permeability. We aimed at assessing the effect of food components on the intestinal permeability (IP) and on inflammatory markers in individuals with IBD by a single-blind randomized clinical study. Of the 53 individuals included, 47% (n = 25) had been diagnosed with IBD. The participants were divided into 4 groups. IBD patients were allocated to intervention group (n = 14) vs. no intervention group (n = 11), and the same happened with 28 control participants without disease (n = 14 in intervention group vs. n = 14 without intervention). Symptomatology, nutritional status, biochemical parameters (specifically serum zonulin (ZO) to measure IP) were evaluated on all individuals on an eight week period following a diet plan with/without potentially beneficial foods for the IP. At the beginning of the study, there were no significant differences in ZO values between individuals with and without IBD (p > 0.05). The effect of specific food components was inconclusive; however, a trend in the reduction of inflammatory parameters and on the prevalence of gastrointestinal symptomatology was observed. More controlled intervention studies with diet plans, including food components potentially beneficial for the integrity of the intestinal barrier, are of the utmost importance.info:eu-repo/semantics/publishedVersio

Tuning the Biological Activity of Camphorimine Complexes through Metal Selection

This research was funded by FCT—Fundação para a Ciência e a Tecnologia, through projects CQE (UIDB/00100/2020 and UIDP/00100/2020) and C2TN (UID/MULTI/04349/2019), the projects of the Research Unit Institute for Bioengineering and Biosciences—iBB (UIDB/04565/2020 and UIDP/04565/2020), the project LA/P/0140/2020 of the Associate Laboratory Institute for Health and Bioeconomy—i4HB, and a PhD grant to J.P.C. (UI/BD/152244/2021).The cytotoxic activity of four sets of camphorimine complexes based on the Cu(I), Cu(II), Ag(I), and Au(I) metal sites were assessed against the cisplatin-sensitive A2780 and OVCAR3 ovarian cancer cells. The results showed that the gold complexes were ca. one order of magnitude more active than the silver complexes, which in turn were ca. one order of magnitude more active than the copper complexes. An important finding was that the cytotoxic activity of the Ag(I) and Au(I) camphorimine complexes was higher than that of cisplatin. Another relevant aspect was that the camphorimine complexes did not interact significantly with DNA, in contrast with cisplatin. The cytotoxic activity of the camphorimine complexes displayed a direct relationship with the cellular uptake by OVCAR3 cells, as ascertained by PIXE (particle-induced X-ray emission). The levels of ROS (reactive oxygen species) formation exhibited an inverse relationship with the reduction potentials for the complexes with the same metal, as assessed by cyclic voltammetry. In order to gain insight into the toxicity of the complexes, their cytotoxicity toward nontumoral cells (HDF and V79 fibroblasts) was evaluated. The in vivo cytotoxicity of complex 5 using the nematode Caenorhabditis elegans was also assessed. The silver camphorimine complexes displayed the highest selectivity coefficients (activity vs. toxicity).publishersversionpublishe

Neuropsychological profile of amyloid-positive versus amyloid-negative amnestic Mild Cognitive Impairment

Patients diagnosed with amnestic mild cognitive impairment (aMCI) are at high risk of progressing to dementia. It became possible, through the use of biomarkers, to diagnose those patients with aMCI who have Alzheimer's disease. However, it is presently unfeasible that all patients undergo biomarker testing. Since neuropsychological testing is required to make a formal diagnosis of aMCI, it would be interesting if it could be used to predict the amyloid status of patients with aMCI.Fundação para a Ciência e Tecnologia - FCTinfo:eu-repo/semantics/publishedVersio

Extracellular vesicles shed by trypanosoma brucei brucei manipulate host mononuclear cells

Funding Information: Funding: This study was supported by FCT—Foundation for Science and Technology, I.P., through research grant PTDC/CVT-CVT/28908/2017 and by national funds within the scope of Centro de Investigação Interdisciplinar em Sanidade Animal (CIISA, UIDB/00276/2020) and Global Health and Tropical Medicine (GHTM, UID/04413/2020). Funding Information: This study was supported by FCT?Foundation for Science and Technology, I.P., through research grant PTDC/CVT-CVT/28908/2017 and by national funds within the scope of Centro de Investiga??o Interdisciplinar em Sanidade Animal (CIISA, UIDB/00276/2020) and Global Health and Tropical Medicine (GHTM, UID/04413/2020). Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.African trypanosomiasis or sleeping sickness is a zoonotic disease caused by Trypanosoma brucei, a protozoan parasite transmitted by Glossina spp. (tsetse fly). Parasite introduction into mammal hosts triggers a succession of events, involving both innate and adaptive immunity. Macrophages (MΦ) have a key role in innate defence since they are antigen-presenting cells and have a micro-bicidal function essential for trypanosome clearance. Adaptive immune defence is carried out by lymphocytes, especially by T cells that promote an integrated immune response. Like mammal cells, T. b. brucei parasites release extracellular vesicles (TbEVs), which carry macromolecules that can be transferred to host cells, transmitting biological information able to manipulate cell immune response. However, the exact role of TbEVs in host immune response remains poorly understood. Thus, the current study examined the effect elicited by TbEVs on MΦ and T lymphocytes. A combined approach of microscopy, nanoparticle tracking analysis, multiparametric flow cytometry, colourimetric assays and detailed statistical analyses were used to evaluate the influence of TbEVs in mouse mononuclear cells. It was shown that TbEVs can establish direct communication with cells of innate and adaptative immunity. TbEVs induce the differentiation of both M1-and M2-MΦ and elicit the expansion of MHCI+, MHCII+ and MHCI+ MHCII+ MΦ subpopulations. In T lymphocytes, TbEVs drive the overexpression of cell-surface CD3 and the nuclear factor FoxP3, which lead to the differentiation of regulatory CD4+ and CD8+ T cells. Moreover, this study indicates that T. b. brucei and TbEVs seem to display opposite but complementary effects in the host, establishing a balance between parasite growth and controlled immune response, at least during the early phase of infection.publishersversionpublishe