Comment: Kidney exchange to overcome financial barriers to kidney transplantation

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The use of social networking technology in the promotion and scaling up of complex global health initiatives

Western medicine has a long tradition of humanitarian service in low resource countries and in crisis and disaster situations. However, advances in social network technology have dramatically changed the manner in which global health services are delivered. A new generation of healthcare professionals, modeled as social entrepreneurs, utilizing collaborative and nonprofit models is establishing relationships with healthcare professionals in host countries, to actively track early disease detection, scaling up of services and research. Oftentimes, technology allows healthcare professionals to contribute to these efforts remotely and without detracting from their routine clinical work as well as facilitating more flexible pathways for global health training in postgraduate education. This paper examines the limitations and opportunities for the utilization of social networking technology, including health care workers as social entrepreneurs, in early disease detection and in scaling up of services and research. Key words: global healthcare entrepreneurs, global burden of disease, social network technology, low resource countries, scaling up, capacity building, social enterpris

TableHop: an actuated fabric display using transparent electrodes

We present TableHop, a tabletop display that provides controlled self-actuated deformation and vibro-tactile feedback to an elastic fabric surface while retaining the ability for high-resolution visual projection. The TableHop surface is made of a highly stretchable pure spandex fabric that is electrostatically actuated using electrodes mounted on its underside. We use transparent indium tin oxide electrodes and high-voltage modulation to create controlled surface deformations. This setup actuates pixels and creates deformations in the fabric up to $\pm$ 5mm. Since the electrodes are transparent, the fabric surface can function as a diffuser for rear-projected visual images, and avoid occlusion by users. Users can touch and interact with the fabric to create expressive interactions as with any fabric based shape-changing interface. By using frequency modulation in the high-voltage circuit, we can also create localised tactile sensations on the user's finger-tip when touching the surface. We provide detailed simulation results of the shape of the surface deformation and the frequency of the haptic vibrations. These results can be used to build prototypes of different sizes and form-factors. We finally create a working prototype of TableHop that has 30$\times$40 cm surface area and uses a grid of 3$\times$3 transparent electrodes. Our prototype uses a maximum of 2.2 mW and can create tactile vibrations of up to 20 $Hz$. TableHop can be scaled to large interactive surfaces and integrated with other objects and devices. TableHop will improve user interaction experience on 2.5D deformable displays

Use of polyethylene glycol coatings for optical fibre humidity sensing

Humidity induced change in the refractive index and thickness of the polyethylene glycol (PEG) coatings are in situ investigated for a range from 10 to 95%, using an optical waveguide spectroscopic technique. It is experimentally demonstrated that, upon humidity change, the optical and swelling characteristics of the PEG coatings can be employed to build a plastic fibre optic humidity sensor. The sensing mechanism is based on the humidity induced change in the refractive index of the PEG film, which is directly coated onto a polished segment of a plastic optical fibre with dip-coating method. It is observed that PEG, which is a highly hydrophilic material, shows no monotonic linear response to humidity but gives different characteristics for various ranges of humidity levels both in index of refraction and in thickness. It undergoes a physical phase change from a semi-crystal line structure to a gel one at around 80% relative humidity. At this phase change point, a drastic decrease occurs in the index of refraction as well as a drastic increase in the swelling of the PEG film. In addition, PEG coatings are hydrogenated in a vacuum chamber. It is observed that the hydrogen has a preventing effect on the humidity induced phase change in PEG coatings. Finally, the possibility of using PEG coatings in construction of a real plastic fibre optic humidity sensor is discussed. (C) 2008 The Optical Society of Japan

Effective Capacity in Broadcast Channels with Arbitrary Inputs

We consider a broadcast scenario where one transmitter communicates with two receivers under quality-of-service constraints. The transmitter initially employs superposition coding strategies with arbitrarily distributed signals and sends data to both receivers. Regarding the channel state conditions, the receivers perform successive interference cancellation to decode their own data. We express the effective capacity region that provides the maximum allowable sustainable data arrival rate region at the transmitter buffer or buffers. Given an average transmission power limit, we provide a two-step approach to obtain the optimal power allocation policies that maximize the effective capacity region. Then, we characterize the optimal decoding regions at the receivers in the space spanned by the channel fading power values. We finally substantiate our results with numerical presentations.Comment: This paper will appear in 14th International Conference on Wired&Wireless Internet Communications (WWIC

Multiple and Multidimensional life transitions in the context of life-limiting health conditions:Longitudinal study focussing on perspectives of Young Adults, Families and Professionals

Background: There is a dearth of literature that investigates life transitions of young adults (YAs) with life-limiting conditions, families and professionals. The scant literature that is available has methodological limitations, including not listening to the voice of YAs, collecting data retrospectively, at one time point, from one group’s perspective and single case studies. The aim of this study was to address the gaps found in our literature review and provide a clearer understanding of the multiple and multi-dimensional life transitions experienced by YAs and significant others, over a period of time. Methods: This qualitative study used a longitudinal design and data were collected using semi-structured interviews over a 6-month period at 3 time points. Participants included 12 YAs with life-limiting conditions and their nominated significant others (10 family members and 11 professionals). Data were analysed using a thematic analysis approach. Results: Life transitions of YA and significant others are complex; they experience multiple and multi-dimensional transitions across several domains. The findings challenge the notion that all life transitions are triggered by health transitions of YAs, and has highlighted environmental factors (attitudinal and systemic) that can be changed to facilitate smoother transitions in various aspects of their lives. Conclusions: This study makes a unique and significant contribution to literature. It provides evidence and rich narratives for policy makers and service providers to change policies and practices that are in line with the needs of YAs with life-limiting conditions as they transition to adulthood. Families and professionals have specific training needs that have not yet been met fully

Endogenous annexin A1 is a novel protective determinant in nonalcoholic steatohepatitis in mice

Macrophage-derived AnxA1 plays a functional role in modulating hepatic inflammation and fibrogenesis during NASH progression, suggesting the possible use of AnxA1 analogs for therapeutic control of this disease

Search for the standard model Higgs boson in the H to ZZ to 2l 2nu channel in pp collisions at sqrt(s) = 7 TeV

A search for the standard model Higgs boson in the H to ZZ to 2l 2nu decay channel, where l = e or mu, in pp collisions at a center-of-mass energy of 7 TeV is presented. The data were collected at the LHC, with the CMS detector, and correspond to an integrated luminosity of 4.6 inverse femtobarns. No significant excess is observed above the background expectation, and upper limits are set on the Higgs boson production cross section. The presence of the standard model Higgs boson with a mass in the 270-440 GeV range is excluded at 95% confidence level.Comment: Submitted to JHE