All about the marine/sea ice diatom Nitzschia lecointei

Generally, in terms of growth N. lecointei seems quite tolerant to changes in pH and pCO2, probably due to the fact that this species grows in an environment with large seasonal variations in the carbonate system. However, increased pCO2 resulted in physiological changes that may have important ecological consequences, such as cellular stoichiometry. For instance, we observed changes in carbon metabolism, and fatty acid content and composition, that did not affect the growth rate. When the experimental period was increased (194 days, ca. 60 asexual generations), we observed a small reduction in growth at 960 µatm pCO2 after 147 days. Carbon metabolism was significantly affected, resulting in higher cellular release of dissolved organic carbon. When studying the synergism between temperature (−1.8 and 2.5°C) and pCO2 (390 and 960 μatm), synergism was detected in growth rate and acyl lipid fatty acid content. Carbon enrichment only promoted (3 %) growth rate closer to the optimal growth, but not at the control temperature (−1.8°C). Optimal growth rate was observed around 5°C in a separate experiment. The total content of fatty acids was reduced at elevated pCO2, but only at the control temperature. PUFAs were reduced at high pCO2. When combining increased temperature and different salinity conditions, the growth rate was higher at 3°C than at -1.8°C. Salinity 10 clearly limited growth rate and the highest growth rates were found at salinity 20 and 35. In another experiment, high and low temperature together with treatments simulating ice formation and melting conditions were studied. Here, the highest levels of oxidative stress were found in low temperature and ice melting treatments, respectively. With respect to 9 weeks in the dark, cell numbers were higher at -1.5°C compared to 3°C, but when retrieved to light conditions, after one week higher cell numbers were observed at 3°C versus -1.5°C. Furthermore, cell numbers were lower when acetateUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Elevated expression of type VII collagen in the skin of patients with systemic sclerosis. Regulation by transforming growth factor-beta.

A hallmark of systemic sclerosis (SSc) is the development of tissue fibrosis. Excessive production of several connective tissue components normally present in the dermis, including type I, III, V, and VI collagens as well as fibronectin and proteoglycans, is a consistent finding in the skin of SSc patients. Type VII collagen is a major constituent of anchoring fibrils, present in the skin at the dermal-epidermal basement membrane zone. TGF-beta has been shown to upregulate the expression of the type VII collagen gene. In this study, we assessed the expression of type VII collagen and TGF-beta in the skin of patients with SSc. Indirect immunofluorescence showed an abundance of type VII collagen in the patients\u27 skin, including the dermis. Ultrastructural analysis of SSc skin revealed an abundance of fibrillar material, possibly representing type VII collagen. The increased expression of type VII collagen epitopes was accompanied by the elevated expression of immunodetectable TGF-beta 1 and TGF-beta 2. Dermal fibroblasts cultured from the affected individuals showed a statistically significant (P \u3c 0.02) increase in the expression of type VII collagen at the mRNA level, as detected by reverse transcription-PCR with a mutated cDNA as an internal standard, and increased deposition of the protein as assessed by indirect immunofluorescence. Thus, type VII collagen is abundantly present in SSc patients\u27 dermis, a location not characteristic of its normal distribution, and its aberrant expression may relate to the presence of TGF-beta in the same topographic distribution. The presence of type VII collagen in the dermis may contribute to the tightly bound and indurated appearance of the affected skin in SSc patients

The escape of Lyman photons from a young starburst: the case of Haro 11

(Abridged) Lyman-alpha (Lya) is a dominant probe of the galaxy population at high-z. However, interpretation of data drawn from Lya alone hinges on the Lya escape fraction which, due to the complex radiative transport, may vary greatly. Here we map the Lya emission from local starburst Haro 11, a Lya emitter and the only known candidate for low-z Lyman continuum emission (LyC). To aid in the interpretation we perform a detailed multi-wavelength analysis and model the stellar population, dust distribution, ionising photon budget, and star-cluster population. We use archival X-ray observations to further constrain properties of the starburst and estimate the HI column density. The Lya morphology is found to be strongly decoupled from stellar and nebular (H-alpha) morphologies. General surface photometry finds only very slight correlation between Lya and H-halpha, E(B-V), and stellar age. Only around the central Lya-bright cluster do we find the Lya/Ha ratio at values predicted by recombination theory. The total Lya escape fraction is found to be just 3%. We compute that ~90% of the Lya photons that escape do so after undergoing multiple resonance scattering events, masking their point of origin. This leads to a largely symmetric distribution and, by increasing the distance that photons must travel to escape, decreases the escape probability significantly. While dust must ultimately be responsible for the destruction of Lya, it plays little role in governing the observed morphology, which is regulated more by ISM kinematics and geometry. We find tentative evidence for local Lya equivalent width in the immediate vicinity of star-clusters being a function of cluster age, consistent with hydrodynamic studies. We estimate the ionising photon production and further constrain the escape fraction at 900 AA to <~9% .Comment: In press for MNRAS. 18 pages, 9 figures. Version with full resolution images to be found at http://www.astro.su.se/~matthew/english/papers/hayes_lya_haro11_hires.pd

Evaluación formativa como estrategia pedagógica para el fortalecimiento de la resolución de problemas en el aprendizaje de las matemáticas mediante la aplicación de las TIC de los estudiantes del grado tercero de la Institución Educativa Técnica José Cayetano Vásquez.

Este documento presenta los resultados del trabajo de grado realizado en la modalidad de Proyecto de investigación bajo la asesoría del docente Andrés Felipe Correa Quiros, para optar por el título de Licenciatura en matemáticas, inscrito en la línea de investigación pedagogía, didáctica y currículo de la Escuela de ciencias de la educación ECEDU, y que se basó en la metodología mixta; se realizó en la Institución Educativa Técnica José Cayetano Vásquez del municipio de Ciénega, Boyacá, en el cual se tuvo en cuenta fuentes de información resientes y las necesidades educativas actuales del contexto. Se presenta la evaluación formativa como estrategia pedagógica para el fortalecimiento de la resolución de problemas en el aprendizaje de las matemáticas mediante la aplicación de las TIC de los estudiantes del grado tercero de la Institución Educativa Técnica José Cayetano Vásquez, pues esta es una estrategia que le permite al docente, institución y sistema educativo reflexionar y hacer seguimiento a los aprendizajes de los estudiantes de manera constante mediante la recolección de información, para así poder analizar y reorientar las estrategias pedagógicas del proceso de enseñanza y aprendizaje por ende a mejorar la calidad educativa.This document presents the results of the degree work carried out in the research project modality under the advice of the teacher Andrés Felipe Correa Quiros, to opt for the Bachelor's degree in mathematics, registered in the pedagogy, didactics and curriculum research line of the ECEDU School of Education Sciences, and which was based on the mixed methodology; It was carried out at the José Cayetano Vásquez Technical Educational Institution in the municipality of Ciénega, Boyacá, in which current sources of information and the current educational needs of the context were taken into account. The formative evaluation is presented as a pedagogical strategy to strengthen problem solving in the learning of mathematics through the application of ICT of third grade students of the José Cayetano Vásquez Technical Educational Institution, since this is a strategy that allows the teacher, institution and educational system to reflect and monitor student learning constantly through the collection of information, in order to analyze and reorient the pedagogical strategies of the teaching and learning process, thereby improving educational quality

Estado del arte del control en sistemas organizacionales y técnicos

La perdurabilidad empresarial es una de las preocupaciones sectoriales, regionales y nacionales estudiada desde diferentes ámbitos (económico, social y académico), convirtiéndose en uno de los objetivos multinivel que impulsa el desarrollo y crecimiento de un país. De otro lado, una de las metodologías que está orientada a garantizar el cumplimiento de los objetivos o comportamientos planificados se denomina “sistemas de control” cuya aplicación es interdisciplinaria, tiene su origen en los sistemas técnicos y se traslada a los sistemas organizacionales. Este trabajo desarrolla una revisión bibliográfica del control, desde la en los sistemas técnicos y desde la Psicología, Sociología y disciplinas sociales a los sistemas organizacionales, identificando dos corrientes. La primera corriente, denominada “clásica” en sistemas causales y la segunda, llamada “inteligente”. El trabajo describe en cada corriente la conceptualización, los propósitos, las metodologías, la estructura, la taxonomía y las críticas en los sistemas de control. El control es abordado con diferentes metodologías, dependiendo de la corriente y de la naturaleza de cada sistema, pero tiene un propósito transversal o interdisciplinario que consiste en generar comportamientos esperados o deseables en el sistema, incluyendo alcanzar objetivos establecidos. En cuanto al desarrollo y comprensión, hay un mayor avance en los sistemas técnicos enfocados básicamente hacia la autonomía del sistema, mientras que en los sistemas organizacionales se ha generado la inquietud de evolucionar o generar controles diferentes o eliminar el control, pero las organizaciones continúan aplicando los controles clásicos y generando resultados de no perdurabilidad empresarial.The corporate sustainability is a concern sectoral, regional and national studied from different areas (economic, social, and academic), becoming one of the multilevel objectives driving the development and growth of a country. On the other hand, one of the methodologies that are designed to ensure compliance with the objectives and planned behavior is called "control systems" whose application is interdisciplinary, has its origin in technical systems and moves to organizational systems. This paper develops a literature review of monitoring, from technical systems and from psychology, sociology and organizational disciplines to organizational systems, identifying two streams. The first stream, called "classic" causal systems and the second, called "intelligent". The work described in each current conceptualization, purposes, methodologies, structure, taxonomy and critical control systems. The control is addressed with different methodologies, depending on the flow and nature of each system, but it has a cross-or interdisciplinary purpose is to generate behaviors expected or desirable in the system, including achieving objectives. On the development and understanding, there is a major advance in technical systems focused primarily towards autonomy of the system, while organizational systems has generated concern evolve or generate different control or eliminate control, but organizations continue to apply generating classical controls and enterprise survivability no results

Medida de la noción de conservación de la cantidad : estudio comparativo de un método no verbal frente al método piagetiano clásico

Fac. de PsicologíaTRUEProQuestpu

Implicancias del voto voluntario como derecho democrático para los ciudadanos

La investigación tuvo como objetivo general, determinar las implicancias del voto voluntario como derecho democrático para los ciudadanos. La metodología fue de tipo básico con diseño no experimental de teoría fundamentada y enfoque cualitativo. Los resultados demostraron que el art. 31 de la Constitución Peruana afecta la naturaleza del sufragio, debido a que el voto es impuesto luego de ser establecido como libre, es decir el voto es un derecho y no un deber, este dispositivo no debe ser un acto obligatorio ni de amenaza, ni de sanción. En efecto la falta de identidad nacional se traduciría en la indiferencia y en consecuencia la falta de voluntad para sufragar, la investigación concluyó en modificar el cuarto párrafo del art. 31 de la Constitución Peruana, generaría un bajo nivel de participación electoral en los ciudadanos, una baja legitimidad de las autoridades elegidas, produciría la eliminación de la reglamentación de la multa y de las sanciones administrativas en favor del elector, y gestaría implementar en forma progresiva la educación electoral en todos los niveles educativos con la finalidad de elevar el nivel de responsabilidad ciudadana

Una profesión y una pasión… Ocho años de experiencia audiovisual y los retos de un periodismo en conciencia y posible

Mi sistematización es una mirada desde un punto de vista analítico a mi paso por dos empresas dedicadas al periodismo audiovisual: Telepaís y Cablenoticias, para revisar algunos temas importantes como lo son: las narrativas que se utilizan en los noticieros, las transformaciones tecnológicas, las habilidades y conocimientos que debe tener un periodista a la hora de trabajar en este tipo de programas, las rutinas, la economía política que afecta directamente las agendas y la línea editorial de dichos medios y finalmente unas conclusiones a la luz de mis propias vivencias y teniendo en cuenta algunos referentes teóricos y entrevistas en profundidad sobre cómo llegar a un periodismo audiovisual posible, en medio de los condicionamientos a los que nos enfrentamos a diario

Medida de la noción de conservación de la cantidad : estudio comparativo de un método no verbal frente al método piagetiano clásico

Fac. de PsicologíaTRUEProQuestpu