288 research outputs found
Collective crimenes. The regulation of the crimen havoc
Trabajo de fin de Grado. Grado en Derecho. Curso académico 2016-2017[ES] In this research work, it is intended to analyze the crime of ravages, mainly, based on it´s penal regulation. It is a crime that is scarcely analyzed doctrinally and jurisprudentially, due to its little application by the courts, since we are dealing with a crime almost exclusively related to the crimes of terrorism, because of their close connection.
To be able to analyze this crime, and in general, anyone, a detailed legal-criminal study is developed from several points of view. We will go through all the categories in which the same is divided, its regulation, so as not to violate the principle of no bis in idem. Emphasizing that we are faced with a specific crime of danger in its first section and abstract danger in the second. Until arriving to establish that there is only one closed catalog of possible typical behaviors, with its results. Developing its legal right, iter criminis, antijuridicidad and its competitions. In order to clarify to the reader a definition and a clear content about this criminal figure[EN] In this research work, it is intended to analyze the crime of ravages, mainly, based on it´s penal regulation. It is a crime that is scarcely analyzed doctrinally and jurisprudentially, due to its little application by the courts, since we are dealing with a crime almost exclusively related to the crimes of terrorism, because of their close connection.
To be able to analyze this crime, and in general, anyone, a detailed legal-criminal study is developed from several points of view. We will go through all the categories in which the same is divided, its regulation, so as not to violate the principle of no bis in idem. Emphasizing that we are faced with a specific crime of danger in its first section and abstract danger in the second. Until arriving to establish that there is only one closed catalog of possible typical behaviors, with its results. Developing its legal right, iter criminis, antijuridicidad and its competitions. In order to clarify to the reader a definition and a clear content about this criminal figur
Análisis y mejora del proceso productivo y de su sistema de información de una empresa del sector fitosanitario
[ES] El Trabajo Final de Grado consiste en un análisis de la situación organizacional de la planta junto a un análisis interno de los procesos tras relatar los problemas de dichos dos análisis se pasa a una solución que pasa por una reestructuración de los procesos productivos gracias a la implantación de la herramienta Q-Plant (un sistema de información) para mejorar los tiempos productivos, la medición (estándares de la planta) y la documentanción de la planta.Alcañiz Díaz-Jiménez, V. (2016). Análisis y mejora del proceso productivo y de su sistema de información de una empresa del sector fitosanitario. http://hdl.handle.net/10251/147346TFG
Identificación de los Estilos de Aprendizaje predominantes en estudiantes de secundaria
El presente pretendió determinar los Estilos de Aprendizaje de los alumnos
de secundaria, dentro del Instituto de Educación Secundaria Pedro Álvarez de
Sotomayor, en la localidad de Manzanares (Ciudad Real). Para ello se utilizaron
muestras de ambos ciclos de secundaria, entre los alumnos de segundo y cuarto
de Educación Secundaria Obligatoria (E.S.O.). De igual modo, se examinaron las
preferencias entre los distintos cursos, así como los posibles cambios acaecidos
en educación secundaria y los alumnos de cuarto curso de la Facultad de
Ciencias del Deporte de Toledo.
Para dicho cometido se compuso una muestra de 120 sujetos (n=120) y se
aplicó el Cuestionario de Honey-Alonso (CHAEA) (Alonso et al., 1994). Los
resultados que se obtuvieron manifestaron preferencias de los sujetos –en el
siguiente orden– por los estilos “Reflexivo”, “Pragmático”, “Teórico” y “Activo”. Una
vez efectuado el tratamiento estadístico, no se encontraron diferencias
significativas entre los alumnos de los dos cursos examinados. De los contrastes
estadísticos de los resultados totales de secundaria con otras muestras de
representación académica (Facultad de Ciencias del Deporte de Toledo), se
obtuvieron, a rasgos generales, resultados muy similares que los de secundaria.
Se ha de resaltar la interesante utilidad de aplicar esta metodología cara a
futuras intervenciones docentes para favorecer, desde la calidad, un mayor
desarrollo de los alumnos/as de los distintos centros educativos.
Finalmente, sería interesante ampliar la cuestión con estudios longitudinales
que determinen con mayor precisión la evolución de los alumnos con relación a
sus Estilos de Aprendizaje en función de sus distintas etapas educativas
Nuevas evidencias arqueológicas en la provincia de Soria: posibles aportaciones para el estudio de la presencia militar romana en la Submeseta Norte
This paper presents five new possible fortified settlements recently identified using remote sensing techniques in modern day province of Soria: La Vega and La Magdalena (Quintanas de Gormaz), La Llana-Caño (Bayubas de Abajo), Vega Fría (Berlanga de Duero) and Las Pozas (Aldealafuente). The morpho-typological characteristics and settlement patterns allow us to hypothesize that these are the remains of Roman temporary military sites. The exhaustive analysis of these new archaeological data could have considerable relevance for studying the expansion of the Roman state in this region during the Late Republic (2nd to 1st c. BC).En este artículo se presentan cinco nuevos posibles asentamientos fortificados identificados recientemente mediante técnicas de teledetección en el territorio de la actual provincia de Soria: La Vega y La Magdalena (Quintanas de Gormaz), La Llana-Caño (Bayubas de Abajo), Vega Fría (Berlanga de Duero) y Las Pozas (Aldealafuente). Las características morfo-tipológicas de estos yacimientos, sumadas a su patrón de asentamiento, nos permiten plantear la hipótesis de que se trate de asentamientos militares romanos de carácter temporal o estacional. Estos nuevos datos arqueológicos, que analizaremos de manera exhaustiva, podrían tener una considerable relevancia para el estudio de la expansión del estado romano en esta región en el periodo tardorrepublicano (ss. II-I a. C.)
Computing “Small” 1–Homological Models for Commutative Differential Graded Algebras
We use homological perturbation machinery specific for the algebra category
[13] to give an algorithm for computing the differential structure of a small 1–
homological model for commutative differential graded algebras (briefly, CDGAs).
The complexity of the procedure is studied and a computer package in Mathematica
is described for determining such models.Ministerio de Educación y Ciencia PB98–1621–C02–02Junta de Andalucía FQM–014
Improving the Performance of a Named Entity Extractor by Applying a Stacking Scheme
In this paper we investigate the way of improving the performance
of a Named Entity Extraction (NEE) system by applying machine
learning techniques and corpus transformation. The main resources used
in our experiments are the publicly available tagger TnT and a corpus
of Spanish texts in which named entities occurrences are tagged with
BIO tags. We split the NEE task into two subtasks 1) Named Entity
Recognition (NER) that involves the identification of the group of words
that make up the name of an entity and 2) Named Entity Classification
(NEC) that determines the category of a named entity. We have focused
our work on the improvement of the NER task, generating four different
taggers with the same training corpus and combining them using a
stacking scheme. We improve the baseline of the NER task (Fβ=1 value
of 81.84) up to a value of 88.37. When a NEC module is added to the
NER system the performance of the whole NEE task is also improved.
A value of 70.47 is achieved from a baseline of 66.07
Long-term effects of coronavirus disease 2019 on the cardiovascular system, CV COVID registry: A structured summary of a study protocol
COVID-19; Cardiologia; PronòsticCOVID-19; Cardiología; PronósticoCOVID 19; Cardiology; PrognosisBackground
Patients presenting with the coronavirus-2019 disease (COVID-19) may have a high risk of cardiovascular adverse events, including death from cardiovascular causes. The long-term cardiovascular outcomes of these patients are entirely unknown. We aim to perform a registry of patients who have undergone a diagnostic nasopharyngeal swab for SARS-CoV-2 and to determine their long-term cardiovascular outcomes.
Study and design
This is a multicenter, observational, retrospective registry to be conducted at 17 centers in Spain and Italy (ClinicalTrials.gov number: NCT04359927). Consecutive patients older than 18 years, who underwent a real-time reverse transcriptase-polymerase chain reaction (RT-PCR) for SARS-CoV2 in the participating institutions, will be included since March 2020, to August 2020. Patients will be classified into two groups, according to the results of the RT-PCR: COVID-19 positive or negative. The primary outcome will be cardiovascular mortality at 1 year. The secondary outcomes will be acute myocardial infarction, stroke, heart failure hospitalization, pulmonary embolism, and serious cardiac arrhythmias, at 1 year. Outcomes will be compared between the two groups. Events will be adjudicated by an independent clinical event committee.
Conclusion
The results of this registry will contribute to a better understanding of the long-term cardiovascular implications of the COVID19.SB. Research grant (COV20/00040) from the Carlos III Institute, Madrid, Spain
How to involve students in formative assessment. The value of feedback
La implicación del alumnado en una evaluación que aspira a ser formativa se
justifica desde un criterio ético, que se compromete con el beneficio formativo
para todos los agentes que participan en el proceso de enseñanza y aprendizaje.
Desde una perspectiva de evaluación formativa el feedback recibido y aportado
por el alumnado durante el proceso de enseñanza y aprendizaje constituye un
elemento imprescindible. Bajo esta premisa, en este capítulo se presenta la experiencia
desarrollada en 7 asignaturas de 4 titulaciones en el contexto del Proyecto
de Innovación Implicación del alumnado en la evaluación formativa de competencias
transversales y su repercusión en el proceso de enseñanza-aprendizaje. Se
describen los procedimientos utilizados para comunicar al alumnado el sistema
de evaluación de la asignatura, y se identifican las estrategias empleadas para
ofrecerle feedback durante el proceso de aprendizaje, que le permita mejorar sus
producciones antes de ser calificadas.
Para valorar la experiencia se ha diseñado un cuestionario dirigido al alumnado
con el objeto de conocer su percepción acerca de diversos aspectos del sistema
de evaluación y del tipo de feedback utilizado y un autoinforme semiestructurado
sobre los mismos aspectos para el profesorado, cumplimentados ambos al
finalizar el período de docencia.
Los resultados obtenidos muestran que el feedback ofrecido permitió al alumnado
aprender de los errores y aciertos, y mejorar la realización de la tarea. Además,
cuando fue acompañado del uso de rúbricas ayudó a comprender las características
de la tarea y facilitar su mejoraThe involvement of students in an assessment that aims to be formative is justified
from an ethical criterion, which promotes the educational benefit of all those involved
in the process of teaching and learning. From the perspective of formative
assessment the feedback received and provided by the students during the process
of teaching and learning is a key element. Under this assumption, in this article
we present the experience developed in 7 subjects from 4 degrees in the context
of the Educational Innovation Project entitled Student involvement in formative
assessment of cross-subject competences and its impact on the process of teaching
and learning. We describe the procedures used to communicate to students the
subject evaluation system, and identify the strategies employed to offer feedback
to the students during their learning process, in order that they could improve their
productions before they are marked.
To evaluate the experience we have designed a questionnaire aimed at students with
the purpose to know their perception about several aspects of the evaluation system
of the subjects and the kind of feedback employed, and a semi-structured self-report
about the same aspects filled by the teachers at the end of the teaching time.
Results show that the feedback offered let students to learn from mistakes and
successes, and improve the realization of the task. In addition, when it was accompanied
by the use of rubrics it helped them to understand the features of the
task and to facilitate its improvemen
Artificial Diets with Selective Restriction of Amino Acids and Very Low Levels of Lipids Induce Anticancer Activity in Mice with Metastatic Triple-Negative Breast Cancer
Current treatments for patients with metastatic triple negative breast cancer (TNBC) are generally ineffective. This manuscript shows for the first time that the survival of mice with metastatic TNBC can be markedly increased through dietary manipulation. Our study revealed that the survival of some mice with metastatic TNBC was increased by replacing their normal diet with artificial diets in which the levels of amino acids (AAs) are manipulated, and the levels of lipids are markedly reduced. The anticancer activity of this non-pharmacological strategy was higher than that of drugs currently used in the treatment of patients with metastatic TNBC. This anticancer strategy also increased the survival of mice with other types of metastatic cancers. Manipulation of AA and lipid levels with artificial diets may be a useful strategy to treat patients with metastatic TNBC and other types of disseminated cancer.Patients with metastatic triple negative breast cancer (TNBC) need new therapies to improve the low survival rates achieved with standard treatments. In this work, we show for the first time that the survival of mice with metastatic TNBC can be markedly increased by replacing their normal diet with artificial diets in which the levels of amino acids (AAs) and lipids are strongly manipulated. After observing selective anticancer activity in vitro, we prepared five artificial diets and evaluated their anticancer activity in a challenging model of metastatic TNBC. The model was established by injecting 4T1 murine TNBC cells into the tail vein of immunocompetent BALB/cAnNRj mice. First-line drugs doxorubicin and capecitabine were also tested in this model. AA manipulation led to modest improvements in mice survival when the levels of lipids were normal. Reducing lipid levels to 1% markedly improved the activity of several diets with different AA content. Some mice fed the artificial diets as monotherapy lived much longer than mice treated with doxorubicin and capecitabine. An artificial diet without 10 non-essential AAs, with reduced levels of essential AAs, and with 1% lipids improved the survival not only of mice with TNBC but also of mice with other types of metastatic cancers.Junta de Andalucía 2017/CTS-657, 2019/CTS-657, 2021/CTS-657Universidad de Sevilla VIPPIT-2019-I.5, VIPPIT-2020-I.5, VIPPIT-2021-I.
Artificial Diets with Altered Levels of Sulfur Amino Acids Induce Anticancer Activity in Mice with Metastatic Colon Cancer, Ovarian Cancer and Renal Cell Carcinoma
Sulfur-containing amino acids methionine (Met), cysteine (Cys) and taurine (Tau) are
common dietary constituents with important cellular roles. Met restriction is already known to exert
in vivo anticancer activity. However, since Met is a precursor of Cys and Cys produces Tau, the role
of Cys and Tau in the anticancer activity of Met-restricted diets is poorly understood. In this work,
we screened the in vivo anticancer activity of several Met-deficient artificial diets supplemented with
Cys, Tau or both. Diet B1 (6% casein, 2.5% leucine, 0.2% Cys and 1% lipids) and diet B2B (6% casein,
5% glutamine, 2.5% leucine, 0.2% Tau and 1% lipids) showed the highest activity and were selected
for further studies. Both diets induced marked anticancer activity in two animal models of metastatic
colon cancer, which were established by injecting CT26.WT murine colon cancer cells in the tail vein
or peritoneum of immunocompetent BALB/cAnNRj mice. Diets B1 and B2B also increased survival
of mice with disseminated ovarian cancer (intraperitoneal ID8 Tp53−/− cells in C57BL/6JRj mice)
and renal cell carcinoma (intraperitoneal Renca cells in BALB/cAnNRj mice). The high activity of
diet B1 in mice with metastatic colon cancer may be useful in colon cancer therapy.Junta de Andalucía 2017/CTS-657, 2019/CTS-657, 2021/CTS657Universidad de Sevilla VIPPIT2019-I.5, VIPPIT-2020-I.5, VIPPIT-2021-I.5, VIPPIT-2020-II.
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