714 research outputs found
Generalized entropy for general subregions in quantum gravity
We consider quantum algebras of observables associated with subregions in
theories of Einstein gravity coupled to matter in the limit.
When the subregion is spatially compact or encompasses an asymptotic boundary,
we argue that the algebra is a type II von Neumann factor. To do so in the
former case we introduce a model of an observer living in the region; in the
latter, the ADM Hamiltonian effectively serves as an observer. In both cases
the entropy of states on which this algebra acts is UV finite, and we find that
it agrees, up to a state-independent constant, with the generalized entropy.
For spatially compact regions the algebra is type II, implying the
existence of an entropy maximizing state, which realizes a version of
Jacobson's entanglement equilibrium hypothesis. The construction relies on the
existence of well-motivated but conjectural states whose modular flow is
geometric at an instant in time. Our results generalize the recent work of
Chandrasekaran, Longo, Penington, and Witten on an algebra of operators for the
static patch of de Sitter space.Comment: 60 pages + 22 pages in appendice
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阿拉伯之春:外国投资者何时回归?
阿拉伯之春事件使得外国投资者的风险意识显著增加。调查结果显示,绝大多数投资者偏好希望这种稳定是在民主政权治下的稳定。因此从长期看前景还是乐观的,如果在该地区的政权更迭是民主的且政治稳定,阿拉伯之春事件会增加FDI 且为该地区的经济发展做出贡献
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The Arab Spring: How soon will foreign investors return?
The Arab Spring dramatically increased investors' perceptions of political risk in MENA. An examination of these perceptions indicates long-run optimism that political transitions in the region -- if democratic and coupled with political stability -- could increase FDI and contribute to MENA's economic development
Introduction, dispersal and naturalisation of the Manila clam Ruditapes philippinarum in British estuaries, 1980-2010
The introduction of the Manila clam into British coastal waters in the 1980s was contested by conservation agencies. While recognizing the value of the clam for aquaculture, the government decided that it posed no invasive risk, as British sea temperatures would prevent naturalization. This proved incorrect. Here we establish the pattern of introduction and spread of the species over the first 30 years of its presence in Britain. We report archival research on the sequence of licensed introductions and examine their relationship in time and space to the appearance of wild populations as revealed in the literature and by field surveys. By 2010 the species had naturalized in at least 11 estuaries in southern England. These included estuaries with no history of licensed introduction. In these cases activities such as storage of catch before market or deliberate unlicensed introduction represent the probable mechanisms of dispersal. In any event naturalization is not an inevitable consequence of introduction and the chances of establishment over the period in question were finely balanced. Consequently in Britain the species is not currently aggressively invasive and appears not to present significant risk to indigenous diversity or ecosystem function. However it is likely to gradually continue its spread should sea surface temperatures rise as predicted
Did the AD 853 Mount Churchill eruption trigger societal and climatic impacts in the northern mid-latitudes?
Starvation and recovery in the deep-sea methanotroph Methyloprofundus sedimenti
In the deep ocean, the conversion of methane into derived carbon and energy drives the establishment of diverse faunal communities. Yet specific biological mechanisms underlying the introduction of methane-derived carbon into the food web remain poorly described, due to a lack of cultured representative deep-sea methanotrophic prokaryotes. Here, the response of the deep-sea aerobic methanotroph Methyloprofundus sedimenti to methane starvation and recovery was characterized. By combining lipid analysis, RNA analysis, and electron cryotomography, it was shown that M. sedimenti undergoes discrete cellular shifts in response to methane starvation, including changes in headgroup-specific fatty acid saturation levels, and reductions in cytoplasmic storage granules. Methane starvation is associated with a significant increase in the abundance of gene transcripts pertinent to methane oxidation. Methane reintroduction to starved cells stimulates a rapid, transient extracellular accumulation of methanol, revealing a way in which methane-derived carbon may be routed to community members. This study provides new understanding of methanotrophic responses to methane starvation and recovery, and lays the initial groundwork to develop Methyloprofundus as a model chemosynthesizing bacterium from the deep sea
Simultaneous dual wavelength eye-tracked ultrahigh resolution retinal and choroidal optical coherence tomography
Involvement of Schizosaccharomyces pombe rrp1+ and rrp2+ in the Srs2- and Swi5/Sfr1-dependent pathway in response to DNA damage and replication inhibition
Previously we identified Rrp1 and Rrp2 as two proteins required for the Sfr1/Swi5-dependent branch of homologous recombination (HR) in Schizosaccharomyces pombe. Here we use a yeast two-hybrid approach to demonstrate that Rrp1 and Rrp2 can interact with each other and with Swi5, an HR mediator protein. Rrp1 and Rrp2 form co-localizing methyl methanesulphonate–induced foci in nuclei, further suggesting they function as a complex. To place the Rrp1/2 proteins more accurately within HR sub-pathways, we carried out extensive epistasis analysis between mutants defining Rrp1/2, Rad51 (recombinase), Swi5 and Rad57 (HR-mediators) plus the anti-recombinogenic helicases Srs2 and Rqh1. We confirm that Rrp1 and Rrp2 act together with Srs2 and Swi5 and independently of Rad57 and show that Rqh1 also acts independently of Rrp1/2. Mutants devoid of Srs2 are characterized by elevated recombination frequency with a concomitant increase in the percentage of conversion-type recombinants. Strains devoid of Rrp1 or Rrp2 did not show a change in HR frequency, but the number of conversion-type recombinants was increased, suggesting a possible function for Rrp1/2 with Srs2 in counteracting Rad51 activity. Our data allow us to propose a model placing Rrp1 and Rrp2 functioning together with Swi5 and Srs2 in a synthesis-dependent strand annealing HR repair pathway
Implementation of Green New Product Development Among SMEs: Barriers and Critical Success Factors
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