4,863 research outputs found

    Telegram from Louis J. W. Jeng, President of the Chinese Culture University, to Geraldine Ferraro

    Get PDF
    Telegram from Louis J. W. Jeng, President of the Chinese Culture University, to Geraldine Ferraro. President Jeng offers congratulations on behalf of the university and thanks Ferraro for visiting China the previous year. Telegram has handwritten notes.https://ir.lawnet.fordham.edu/vice_presidential_campaign_correspondence_1984_international/1066/thumbnail.jp

    Vacancy diffusion in the triangular lattice dimer model

    Get PDF
    We study vacancy diffusion on the classical triangular lattice dimer model, sub ject to the kinetic constraint that dimers can only translate, but not rotate. A single vacancy, i.e. a monomer, in an otherwise fully packed lattice, is always localized in a tree-like structure. The distribution of tree sizes is asymptotically exponential and has an average of 8.16 \pm 0.01 sites. A connected pair of monomers has a finite probability of being delocalized. When delocalized, the diffusion of monomers is anomalous:Comment: 15 pages, 27 eps figures. submitted to Physical Review

    PROMOTION OF REPLICATION IN LYMPHOID CELLS BY SPECIFIC THIOLS AND DISULFIDES IN VITRO : EFFECTS ON MOUSE LYMPHOMA CELLS IN COMPARISON WITH SPLENIC LYMPHOCYTES

    Get PDF
    Numerous lines of mouse lymphoid tumors (13 of 22 tested) showed, with increased sensitivity, a property of normal mouse splenic lymphocytes, the potential for growth promotion in vitro by specific thiols added to standard culture media. For lymphoma L1210 (V), structure activity relationships were examined; 9 of 30 thiols promoted growth; the most active was α-thioglycerol, effective at 0.2 ”M. Thiols became oxidized under conditions of tissue culture and had half-lives of less than 8 h. Disulfides of active thiols promoted growth of lymphoma cells. The mitogenic response of splenic lymphocytes to lectins was increased by thiols-disulfides which promoted the growth of lymphoma cells, but the response varied with the mitogen preparation used and under some conditions thiols-disulfides were inhibitory

    Vacancy localization in the square dimer model

    Get PDF
    We study the classical dimer model on a square lattice with a single vacancy by developing a graph-theoretic classification of the set of all configurations which extends the spanning tree formulation of close-packed dimers. With this formalism, we can address the question of the possible motion of the vacancy induced by dimer slidings. We find a probability 57/4-10Sqrt[2] for the vacancy to be strictly jammed in an infinite system. More generally, the size distribution of the domain accessible to the vacancy is characterized by a power law decay with exponent 9/8. On a finite system, the probability that a vacancy in the bulk can reach the boundary falls off as a power law of the system size with exponent 1/4. The resultant weak localization of vacancies still allows for unbounded diffusion, characterized by a diffusion exponent that we relate to that of diffusion on spanning trees. We also implement numerical simulations of the model with both free and periodic boundary conditions.Comment: 35 pages, 24 figures. Improved version with one added figure (figure 9), a shift s->s+1 in the definition of the tree size, and minor correction

    Load fluctuations drive actin network growth

    Full text link
    The growth of actin filament networks is a fundamental biological process that drives a variety of cellular and intracellular motions. During motility, eukaryotic cells and intracellular pathogens are propelled by actin networks organized by nucleation-promoting factors, which trigger the formation of nascent filaments off the side of existing filaments in the network. A Brownian ratchet (BR) mechanism has been proposed to couple actin polymerization to cellular movements, whereby thermal motions are rectified by the addition of actin monomers at the end of growing filaments. Here, by following actin--propelled microspheres using three--dimensional laser tracking, we find that beads adhered to the growing network move via an object--fluctuating BR. Velocity varies with the amplitude of thermal fluctuation and inversely with viscosity as predicted for a BR. In addition, motion is saltatory with a broad distribution of step sizes that is correlated in time. These data point to a model in which thermal fluctuations of the microsphere or entire actin network, and not individual filaments, govern motility. This conclusion is supported by Monte Carlo simulations of an adhesion--based BR and suggests an important role for membrane tension in the control of actin--based cellular protrusions.Comment: To be published in PNA

    Fiber Optic Tactical Local Network (FOTLAN)

    Get PDF
    A 100 Mbit/s FDDI (fiber distributed data interface) network interface unit is described that supports real-time data, voice and video. Its high-speed interrupt-driven hardware architecture efficiently manages stream and packet data transfer to the FDDI network. Other enhancements include modular single-mode laser-diode fiber optic links to maximize node spacing, optic bypass switches for increased fault tolerance, and a hardware performance monitor to gather real-time network diagnostics

    Selective interlayer ferromagnetic coupling between the Cu spins in YBa2_2 Cu3_3 O7−x_{7-x} grown on top of La0.7_{0.7} Ca0.3_{0.3} MnO3_3

    Full text link
    Studies to date on ferromagnet/d-wave superconductor heterostructures focus mainly on the effects at or near the interfaces while the response of bulk properties to heterostructuring is overlooked. Here we use resonant soft x-ray scattering spectroscopy to reveal a novel c-axis ferromagnetic coupling between the in-plane Cu spins in YBa2_2 Cu3_3 O7−x_{7-x} (YBCO) superconductor when it is grown on top of ferromagnetic La0.7_{0.7} Ca0.3_{0.3} MnO3_3 (LCMO) manganite layer. This coupling, present in both normal and superconducting states of YBCO, is sensitive to the interfacial termination such that it is only observed in bilayers with MnO_2but not with La0.7_{0.7} Ca0.3_{0.3} interfacial termination. Such contrasting behaviors, we propose, are due to distinct energetic of CuO chain and CuO2_2 plane at the La0.7_{0.7} Ca0.3_{0.3} and MnO2_2 terminated interfaces respectively, therefore influencing the transfer of spin-polarized electrons from manganite to cuprate differently. Our findings suggest that the superconducting/ferromagnetic bilayers with proper interfacial engineering can be good candidates for searching the theorized Fulde-Ferrel-Larkin-Ovchinnikov (FFLO) state in cuprates and studying the competing quantum orders in highly correlated electron systems.Comment: Please note the change of the title. Text might be slightly different from the published versio

    Spiral model, jamming percolation and glass-jamming transitions

    Full text link
    The Spiral Model (SM) corresponds to a new class of kinetically constrained models introduced in joint works with D.S. Fisher [8,9]. They provide the first example of finite dimensional models with an ideal glass-jamming transition. This is due to an underlying jamming percolation transition which has unconventional features: it is discontinuous (i.e. the percolating cluster is compact at the transition) and the typical size of the clusters diverges faster than any power law, leading to a Vogel-Fulcher-like divergence of the relaxation time. Here we present a detailed physical analysis of SM, see [5] for rigorous proofs. We also show that our arguments for SM does not need any modification contrary to recent claims of Jeng and Schwarz [10].Comment: 9 pages, 7 figures, proceedings for StatPhys2

    Metal-insulator transition from combined disorder and interaction effects in Hubbard-like electronic lattice models with random hopping

    Full text link
    We uncover a disorder-driven instability in the diffusive Fermi liquid phase of a class of many-fermion systems, indicative of a metal-insulator transition of first order type, which arises solely from the competition between quenched disorder and interparticle interactions. Our result is expected to be relevant for sufficiently strong disorder in d = 3 spatial dimensions. Specifically, we study a class of half-filled, Hubbard-like models for spinless fermions with (complex) random hopping and short-ranged interactions on bipartite lattices, in d > 1. In a given realization, the hopping disorder breaks time reversal invariance, but preserves the special ``nesting'' symmetry responsible for the charge density wave instability of the ballistic Fermi liquid. This disorder may arise, e.g., from the application of a random magnetic field to the otherwise clean model. We derive a low energy effective field theory description for this class of disordered, interacting fermion systems, which takes the form of a Finkel'stein non-linear sigma model [A. M. Finkel'stein, Zh. Eksp. Teor. Fiz. 84, 168 (1983), Sov. Phys. JETP 57, 97 (1983)]. We analyze the Finkel'stein sigma model using a perturbative, one-loop renormalization group analysis controlled via an epsilon-expansion in d = 2 + epsilon dimensions. We find that, in d = 2 dimensions, the interactions destabilize the conducting phase known to exist in the disordered, non-interacting system. The metal-insulator transition that we identify in d > 2 dimensions occurs for disorder strengths of order epsilon, and is therefore perturbatively accessible for epsilon << 1. We emphasize that the disordered system has no localized phase in the absence of interactions, so that a localized phase, and the transition into it, can only appear due to the presence of the interactions.Comment: 47 pages, 25 figures; submitted to Phys. Rev. B. Long version of arXiv:cond-mat/060757

    Pathophysiological changes in inner hair cell ribbon synapses in the ageing mammalian cochlea

    Get PDF
    Mammalian cochlear inner hair cells (IHCs) are specialized sensory receptors able to provide dynamic coding of sound signals. This ability is largely conferred by their ribbon synapses, which tether a large number of vesicles at the IHC's presynaptic active zones, allowing high rates of sustained synaptic transmission onto the afferent fibres. How the physiological and morphological properties of ribbon synapses change with age remains largely unknown. Here, we have investigated the biophysical and morphological properties of IHC ribbon synapses in the ageing cochlea (9–12 kHz region) of four mouse strains commonly used in hearing research: early‐onset progressive hearing loss (C57BL/6J and C57BL/6NTac) and ‘good hearing’ strains (C57BL/6NTacCdh23+ and C3H/HeJ). We found that with age, both modiolar and pillar sides of the IHC exhibited a loss of ribbons, but there was an increased volume of those that remained. These morphological changes, which only occurred after 6 months of age, were correlated with the level of hearing loss in the different mouse strains, being most severe for C57BL/6NTac and C57BL/6J, less so for C57BL/6NTacCdh23+ and absent for C3H/HeJ strains. Despite the age‐related reduction in ribbon number in three of the four strains, the size and kinetics of Ca2+‐dependent exocytosis, as well as the replenishment of synaptic vesicles, in IHCs was not affected. The degree of vesicle release at the fewer, but larger, individual remaining ribbon synapses colocalized with the post‐synaptic afferent terminals is likely to increase, indicating the presence of a previously unknown degree of functional compensation in the ageing mouse cochlea
    • 

    corecore