6 research outputs found
Antimicrobial Activity of Few Medicinal Plants against Clinically Isolated Human Cariogenic Pathogens—An In Vitro Study
Hexane, ethyl acetate, ethanol and methanol extracts of
Psidium guajava, Terminalia chebula, Mimusops elengi and
Achyranthes aspera were tested against the dental caries
causing bacteria Streptococcus mutans and fungus
Candida albicans isolated from caries infected
patients. All the four extracts of P. guajava
showed activity against both S. mutans and
C. albicans. Maximum zone of inhibition was
observed in ethyl acetate of P. guajava. The four
extracts of T. chebula and M.
elengi showed antibacterial activity against S.
mutans. M. elengi extracts and ethanol
extract of T. chebula did not show any antifungal
activity against C. albicans. Except for the
hexane extract of A. aspera, the other three
extracts showed activity against the tested microbes. The ethyl
acetate P. guajava leaf extract showed the
minimum inhibitory concentration (MIC) against S.
mutans to be <0.076 mg/mL in both MHB and
BHI. The P. guajava ethyl acetate extract was
subjected to GC-MS