Impact of Information Technology on Employee Attitudes: A Longitudinal Field Study

This longitudinal study examined the impact of an information technology system on the job and employee attitudes in a parts distribution center for a Fortune 500 company. Data were collected prior to, during, and following the implementation of an automated information technology system. Results of both the within subjects (N=24) and between subjects (N=58) analyses indicated that the automated technology reduced motivational and increased mechanistic aspects of the job as well as reduced employee attitudes

Monitoring wild animal communities with arrays of motion sensitive camera traps

Studying animal movement and distribution is of critical importance to addressing environmental challenges including invasive species, infectious diseases, climate and land-use change. Motion sensitive camera traps offer a visual sensor to record the presence of a broad range of species providing location -specific information on movement and behavior. Modern digital camera traps that record video present new analytical opportunities, but also new data management challenges. This paper describes our experience with a terrestrial animal monitoring system at Barro Colorado Island, Panama. Our camera network captured the spatio-temporal dynamics of terrestrial bird and mammal activity at the site - data relevant to immediate science questions, and long-term conservation issues. We believe that the experience gained and lessons learned during our year long deployment and testing of the camera traps as well as the developed solutions are applicable to broader sensor network applications and are valuable for the advancement of the sensor network research. We suggest that the continued development of these hardware, software, and analytical tools, in concert, offer an exciting sensor-network solution to monitoring of animal populations which could realistically scale over larger areas and time spans

Tyrosine-specific MAPK phosphatases and the control of ERK signaling in PC12 cells

BACKGROUND: Spatio-temporal control of extracellular signal-regulated kinase (ERK) activity, a critical determinant of the cell's response to growth factors, requires timely dephosphorylation of its regulatory tyrosine and/or threonine residue by MAPK phosphatases. We studied the physiological role of kinase interaction motif (KIM)-containing protein tyrosine phosphatases (PTPs) in the control of EGF- and NGF-induced ERK activity in neuroendocrine PC12 cells. RESULTS: We found a single KIM-containing PTP to be endogenously expressed in rat PC12 cells: the transmembrane PTPRR isoform termed PCPTP1. Protein knock-down of PCPTP1, or fourfold overexpression of its mouse orthologue, PTPBR7, left EGF- and NGF-induced ERK1/2 activity in PC12 cells unaltered. Ectopic expression of cytosolic PTPRR isoforms, however, resulted in reduced EGF-induced ERK1/2 activity, an effect that was dependent on the phosphatase activity and the KIM-domain of these PTPs. CONCLUSION: The finding that robust changes in tyrosine-specific MAPK phosphatase expression levels have minor effects on temporal ERK1/2 activity control in PC12 cells suggests that dual-specificity MAPK phosphatases may act as major regulators of growth factor-induced ERK1/2 signaling in these cells

[NEt3Me][O3], Synthesis, Crystal Growth and Crystal Structure Analysis

[NEt3Me][O3] was obtained for the first time by an ion exchange reaction in liquid ammonia. It was thoroughly characterized by X‐Ray diffraction [P21; a=598.51(4) pm, b=1032.03(7) pm, c=723.83(6) pm, β=92.677(3)°, R=0.0384, 15070 reflections] applying non‐spherical and spherical atomic form factors for the refinements. In contrast to previous reported ozonides, [NEt3Me][O3] is the first to adopt the tungsten carbide (WC) motif of cation/ anion arragemnent and shows an untypical hydrogen bond between the central oxygen atom of the ozonide and the cation. Additionally, IR spectroscopy as well as quantum‐chemical calculations were applied to further characterize the compound. The obtained ozonide showed high solubility in ammonia as well as acetonitrile and good properties as a synthon in ozonide chemistry

Na4IrO4: Square-Planar Coordination of a Transition Metal in d5 Configuration due to Weak On-Site Coulomb Interactions

Local environments and valence electron counts primarily determine the electronic states and physical properties of transition metal complexes. For example, square-planar surroundings found in transition oxometalates such as curprates are usually associated with the d8 or d9 electron configuration. In this work, we address an exotic square-planar mono-oxoanion [IrO4]^{4-} as observed in Na4IrO4 with Ir(IV) in d^5 configuration, and characterize the chemical bonding by experiment and ab initio calculations. We find that Na4IrO4 in its ground state evolves a square-planar coordination for Ir(IV) because of the weak Coulomb repulsion of Ir-5d electrons. In contrast, in its 3d counterpart, Na4CoO4, Co(IV) is in tetrahedral coordination, due to strong electron correlation. Na4IrO4 thus may serve as a simple paradigmatic platform for studying the ramifications of Hubbard type Coulomb interactions on local geometries.Comment: 4 pages, 4 figures, accepted by Ang. Chem. Int. Ed. (2015

A Generalized Power System Architecture Sizing and Analysis Framework

The aeronautics industry has been challenged to increase efficiency, reduce noise and emissions, and decrease dependency on carbon-based fuels. To address these needs, NASA has identified and begun to pursue electrified aircraft as a possible solution. The power system for an electric aircraft can exist in many different forms, however; at the early design stage the engineer(s) must identify whether a hybrid- or turbo- electric solution may be best, whether the power transmission system is to be AC or DC, and to ultimately answer the question: does the electric solution provide a net system benefit compared to the fully mechanical solution? This paper describes a generalized power system architecture sizing and analysis framework to provide a mechanism to answering these questions, along with an example based on the STARC-ABL Architecture

Scp160p is required for translational efficiency of codon-optimized mRNAs in yeast

The budding yeast multi-K homology domain RNA-binding protein Scp160p binds to >1000 messenger RNAs (mRNAs) and polyribosomes, and its mammalian homolog vigilin binds transfer RNAs (tRNAs) and translation elongation factor EF1alpha. Despite its implication in translation, studies on Scp160p's molecular function are lacking to date. We applied translational profiling approaches and demonstrate that the association of a specific subset of mRNAs with ribosomes or heavy polysomes depends on Scp160p. Interaction of Scp160p with these mRNAs requires the conserved K homology domains 13 and 14. Transfer RNA pairing index analysis of Scp160p target mRNAs indicates a high degree of consecutive use of iso-decoding codons. As shown for one target mRNA encoding the glycoprotein Pry3p, Scp160p depletion results in translational downregulation but increased association with polysomes, suggesting that it is required for efficient translation elongation. Depletion of Scp160p also decreased the relative abundance of ribosome-associated tRNAs whose codons show low potential for autocorrelation on mRNAs. Conversely, tRNAs with highly autocorrelated codons in mRNAs are less impaired. Our data indicate that Scp160p might increase the efficiency of tRNA recharge, or prevent diffusion of discharged tRNAs, both of which were also proposed to be the likely basis for the translational fitness effect of tRNA pairin

Host specificity in a diverse Neotropical tick community: an assessment using quantitative network analysis and host phylogeny

Background: Host specificity is a fundamental determinant of tick population and pathogen transmission dynamics, and therefore has important implications for human health. Tick host specificity is expected to be particularly high in the tropics, where communities of ticks, hosts and pathogens are most diverse. Yet the degree to which tropical tick species are host-specific remains poorly understood. Combining new field data with published records, we assessed the specificity of tick-host associations in Panama, a diverse Neotropical region. Methods: The resulting dataset includes 5,298 adult ticks belonging to 41 species of eight genera that were directly collected from 68 vertebrate host species of 17 orders. We considered three important aspects of tick host specificity: (i) the relative ecological importance of each host species (structural specificity); (ii) relatedness among host species (phylogenetic specificity); and (iii) spatial scale-dependence of tick-host relationships (geographical specificity). Applying quantitative network analyses and phylogenetic tools with null model comparisons, we assessed the structural and phylogenetic specificity across three spatial scales, ranging from central Panama to countrywide. Further, we tested whether species-rich tick genera parasitized a wider variety of hosts than species-poor genera, as expected when ticks specialize on different host species. Results: Most tick species showed high structural and/or phylogenetic specificity in the adult stage. However, after correcting for sampling effort, we found little support for geographical specificity. Across the three scales, adult ticks tended to be specific to a limited number of host species that were phylogenetically closely related. These host species in turn, were parasitized by tick species from distinct genera, suggesting switching among distantly related hosts is common at evolutionary timescales. Further, there was a strong positive relationship between the taxonomic richness of the tick genera and that of their hosts, consistent with distinct tick species being relatively specific to different host species. Conclusions: Our results indicate that in the adult stage, most ticks in the diverse Neotropical community studied are host specialists. This contrasts with earlier assessments, but agrees with findings from other host-parasite systems. High host specificity in adult ticks implies high susceptibility to local tick-host co-extirpation, limited ability to colonize new habitats and limited potential for interspecific pathogen transmission.Background: Host specificity is a fundamental determinant of tick population and pathogen transmission dynamics, and therefore has important implications for human health. Tick host specificity is expected to be particularly high in the tropics, where communities of ticks, hosts and pathogens are most diverse. Yet the degree to which tropical tick species are host-specific remains poorly understood. Combining new field data with published records, we assessed the specificity of tick-host associations in Panama, a diverse Neotropical region. Methods: The resulting dataset includes 5,298 adult ticks belonging to 41 species of eight genera that were directly collected from 68 vertebrate host species of 17 orders. We considered three important aspects of tick host specificity: (i) the relative ecological importance of each host species (structural specificity); (ii) relatedness among host species (phylogenetic specificity); and (iii) spatial scale-dependence of tick-host relationships (geographical specificity). Applying quantitative network analyses and phylogenetic tools with null model comparisons, we assessed the structural and phylogenetic specificity across three spatial scales, ranging from central Panama to countrywide. Further, we tested whether species-rich tick genera parasitized a wider variety of hosts than species-poor genera, as expected when ticks specialize on different host species. Results: Most tick species showed high structural and/or phylogenetic specificity in the adult stage. However, after correcting for sampling effort, we found little support for geographical specificity. Across the three scales, adult ticks tended to be specific to a limited number of host species that were phylogenetically closely related. These host species in turn, were parasitized by tick species from distinct genera, suggesting switching among distantly related hosts is common at evolutionary timescales. Further, there was a strong positive relationship between the taxonomic richness of the tick genera and that of their hosts, consistent with distinct tick species being relatively specific to different host species. Conclusions: Our results indicate that in the adult stage, most ticks in the diverse Neotropical community studied are host specialists. This contrasts with earlier assessments, but agrees with findings from other host-parasite systems. High host specificity in adult ticks implies high susceptibility to local tick-host co-extirpation, limited ability to colonize new habitats and limited potential for interspecific pathogen transmission

Host body size and the diversity of tick assemblages on Neotropical vertebrates

AbstractIdentifying the factors that influence the species diversity and distribution of ticks (Acari: Ixodida) across vertebrate host taxa is of fundamental ecological and medical importance. Host body size is considered one of the most important determinants of tick abundance, with larger hosts having higher tick burdens. The species diversity of tick assemblages should also be greater on larger-bodied host species, but empirical studies testing this hypothesis are lacking. Here, we evaluate this relationship using a comparative dataset of feeding associations from Panama between 45 tick species and 171 host species that range in body size by three orders of magnitude. We found that tick species diversity increased with host body size for adult ticks but not for immature ticks. We also found that closely related host species tended to have similar tick species diversity, but correcting for host phylogeny did not alter the relationships between host body size and tick species diversity. The distribution of tick species was highly aggregated, with approximately 20% of the host species harboring 80% of all tick species, following the Pareto principle or 20/80 Rule. Thus, the aggregated pattern commonly observed for tick burdens and disease transmission also holds for patterns of tick species richness. Our finding that the adult ticks in this system preferentially parasitize large-bodied host species suggests that the ongoing anthropogenic loss of large-bodied vertebrates is likely to result in host-tick coextinction events, even when immature stages feed opportunistically. As parasites play critical roles in ecological and evolutionary processes, such losses may profoundly affect ecosystem functioning and services