U.K. AND U.S. MULTINATIONAL CAPITAL BUDGETING AND FINANCING DECISIONS

The purpose of this study is to investigate the capital budgeting and financing decisions of UK and US multinational enterprises. Following a survey approach, this study examines the impact that the general equilibrium and the disequilibrium schools of reasoning have upon international investment and financing decisions of the multinational. Further, the degree of centralisation in financial policy is investigated in the light of the two schools of thought which partition corporate finance theory. A conjoint methodology is utilised in order to evaluate the gravity of various environmental issues upon the foreign direct investment decision as well as the utilities for discrete levels of those determinants. The research inquiry is enriched with in-depth interviews with fourteen senior finance managers of British based multinational companies

The Role of Project Coordinators in European Commission Framework Programme Projects

This report presents key findings of the Innovation Radar Project Coordinators Survey in Framework Programme Research and Innovation projects, a purposeful sample of European Framework Programme (FP) Project Coordinators (PC). The objective is to identify the practices and activities of PCs leading EU FP projects and to understand their impact on innovation outcomes. The survey findings confirm the lynchpin role of PCs in the European FP R&I projects. Their role clearly extends significantly beyond that identified in the Horizon 2020 User Guide which sees the PC as “the main contact point between the consortium and the Commission for a particular grant”. The PC is far more than simply “the proposal initiator in the submission phase” but taking account of their prime role in project conceptualisation and consortia formation, the PC is in effect the principal translator of the EC funded research programme and responsible for how the majority of the European research budget is invested. Identifying the PC as a scientific entrepreneur significantly changes how the PC role is viewed. From an EC perspective, recognising the PC as a scientific entrepreneur means their engagement with the PC during the project should be less about monitoring and oversight during project implementation, and more about providing the entrepreneur with support.JRC.B.6-Digital Econom

What factors can help COVID-19 patients to recover quickly in Pakistan

The research paper uncovers the socioeconomic factors which are associated with the recovery of coronavirus in Pakistan. Using a self-designed questionnaire, we collected the data from 170 corona recovered patients and applied Multiple linear regression to predict the effect of socioeconomic factors. The paper finds that patients aged between 36 and 46 years take around 3 more days to recover, whereas, patients aged above than 46 years take around 7 more days to recover in comparison to the young adults (17-25 years). In addition, patients who live in urban areas recover almost 1.5 days earlier than those who live in rural areas. Patients who have other serious diseases take almost 1.7 more days to recover in comparison to those who do not have any disease. Patients who smoke take 2 more days to recover in comparison to those who do not smoke. Moreover, obese people take almost 2.6 more days to recover in comparison to those who have a normal body mass index. Surprisingly, income, gender, and education remain insignificant in relation to the recovery days. We suggest, people above 46 should be given extra care, policies regarding smoking cessation, and lowering obesity should be implemented to combat coronavirus

The Role of Project Coordinators in European Commission Framework Programme Projects

Programme Research and Innovation projects, a purposeful sample of European Framework Programme (FP) Project Coordinators (PC). The objective is to identify the practices and activities of PCs leading EU FP projects and to understand their impact on innovation outcomes. The survey findings confirm the lynchpin role of PCs in the European FP R&I projects. Their role clearly extends significantly beyond that identified in the Horizon 2020 User Guide which sees the PC as “the main contact point between the consortium and the Commission for a particular grant”. The PC is far more than simply “the proposal initiator in the submission phase” but taking account of their prime role in project conceptualisation and consortia formation, the PC is in effect the principal translator of the EC funded research programme and responsible for how the majority of the European research budget is invested. Identifying the PC as a scientific entrepreneur significantly changes how the PC role is viewed. Recognising the PC as a scientific entrepreneur means their engagement with the PC during the project should be less about monitoring and oversight during project implementation, and more about providing the entrepreneur with support

Evaulating the impact of design awards for housing

Awards for housing design allow the opportunity to reward, celebrate and encourage the best in residential design. They also provide the opportunity to learn about new forms of living environment and the potential quality of development which housing developers and designers can deliver. Such issues areof paramount importance as the quality of living environments has a significant impact on our quality of life.This report seeks to better the understanding of the contribution made by housing design awards in encouraging better practice in design quality, innovation and sustainability

Unexpected Occurrence of Plasmid-Mediated Quinolone Resistance Determinants in Environmental Aeromonas spp.

Identification of plasmid-mediated qnr genes outside Enterobacteriaceae underlines a possible diffusion of those resistance determinants within gram-negative rods

Gravitational Waves From Known Pulsars: Results From The Initial Detector Era

We present the results of searches for gravitational waves from a large selection of pulsars using data from the most recent science runs (S6, VSR2 and VSR4) of the initial generation of interferometric gravitational wave detectors LIGO (Laser Interferometric Gravitational-wave Observatory) and Virgo. We do not see evidence for gravitational wave emission from any of the targeted sources but produce upper limits on the emission amplitude. We highlight the results from seven young pulsars with large spin-down luminosities. We reach within a factor of five of the canonical spin-down limit for all seven of these, whilst for the Crab and Vela pulsars we further surpass their spin-down limits. We present new or updated limits for 172 other pulsars (including both young and millisecond pulsars). Now that the detectors are undergoing major upgrades, and, for completeness, we bring together all of the most up-to-date results from all pulsars searched for during the operations of the first-generation LIGO, Virgo and GEO600 detectors. This gives a total of 195 pulsars including the most recent results described in this paper.United States National Science FoundationScience and Technology Facilities Council of the United KingdomMax-Planck-SocietyState of Niedersachsen/GermanyAustralian Research CouncilInternational Science Linkages program of the Commonwealth of AustraliaCouncil of Scientific and Industrial Research of IndiaIstituto Nazionale di Fisica Nucleare of ItalySpanish Ministerio de Economia y CompetitividadConselleria d'Economia Hisenda i Innovacio of the Govern de les Illes BalearsNetherlands Organisation for Scientific ResearchPolish Ministry of Science and Higher EducationFOCUS Programme of Foundation for Polish ScienceRoyal SocietyScottish Funding CouncilScottish Universities Physics AllianceNational Aeronautics and Space AdministrationOTKA of HungaryLyon Institute of Origins (LIO)National Research Foundation of KoreaIndustry CanadaProvince of Ontario through the Ministry of Economic Development and InnovationNational Science and Engineering Research Council CanadaCarnegie TrustLeverhulme TrustDavid and Lucile Packard FoundationResearch CorporationAlfred P. Sloan FoundationAstronom

Exploring Cosmic Origins with CORE: Cosmological Parameters

We forecast the main cosmological parameter constraints achievable with theCORE space mission which is dedicated to mapping the polarisation of the CosmicMicrowave Background (CMB). CORE was recently submitted in response to ESA'sfifth call for medium-sized mission proposals (M5). Here we report the resultsfrom our pre-submission study of the impact of various instrumental options, inparticular the telescope size and sensitivity level, and review the great,transformative potential of the mission as proposed. Specifically, we assessthe impact on a broad range of fundamental parameters of our Universe as afunction of the expected CMB characteristics, with other papers in the seriesfocusing on controlling astrophysical and instrumental residual systematics. Inthis paper, we assume that only a few central CORE frequency channels areusable for our purpose, all others being devoted to the cleaning ofastrophysical contaminants. On the theoretical side, we assume LCDM as ourgeneral framework and quantify the improvement provided by CORE over thecurrent constraints from the Planck 2015 release. We also study the jointsensitivity of CORE and of future Baryon Acoustic Oscillation and Large ScaleStructure experiments like DESI and Euclid. Specific constraints on the physicsof inflation are presented in another paper of the series. In addition to thesix parameters of the base LCDM, which describe the matter content of aspatially flat universe with adiabatic and scalar primordial fluctuations frominflation, we derive the precision achievable on parameters like thosedescribing curvature, neutrino physics, extra light relics, primordial heliumabundance, dark matter annihilation, recombination physics, variation offundamental constants, dark energy, modified gravity, reionization and cosmicbirefringence. (ABRIDGED

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

A Next-Generation Liquid Xenon Observatory for Dark Matter and Neutrino Physics

The nature of dark matter and properties of neutrinos are among the mostpressing issues in contemporary particle physics. The dual-phase xenontime-projection chamber is the leading technology to cover the availableparameter space for Weakly Interacting Massive Particles (WIMPs), whilefeaturing extensive sensitivity to many alternative dark matter candidates.These detectors can also study neutrinos through neutrinoless double-beta decayand through a variety of astrophysical sources. A next-generation xenon-baseddetector will therefore be a true multi-purpose observatory to significantlyadvance particle physics, nuclear physics, astrophysics, solar physics, andcosmology. This review article presents the science cases for such a detector.<br