Bioactive Compounds and Antioxidant Capacity of Moringa Leaves Grown in Spain Versus 28 Leaves Commonly Consumed in Pre-Packaged Salads

Total antioxidant capacity (TAC) evaluated by ferric ion reducing antioxidant power (FRAP) assay, ABTS, DPPH, and Oxygen radical absorbance capacity (ORAC) assay, and total polyphenol content (TPC) by Folin–Ciocalteu were determined in Moringa oleifera leaves (MO) grown in Spain, and compared with 28 different vegetable leaves pre-packaged for consumption as a salad. Total carotenoids, flavonoids, and chlorophylls were also determined in the samples with highest TAC. Two different extraction procedures were applied to obtain the methanolic fraction and the lipophilic and hydrophilic fractions. The highest TAC and TPC contents were found in MO. High values were also found in red chicory, “lollo rosso”, and oak lettuce. The lowest TAC and TPC values were obtained in iceberg lettuce. The correlations between the extraction procedures and methods assayed were high and statistically significant. In the light of these results, we suggest the addition of MO to the existing range of fresh-cut salad foods would increase their antioxidant content by up to six times.Spanish Ministry of Economy and Competitiveness RTI2018-099835-A-I0

Usos, apropiación y construcción de significados del espacio urbano por parte de la niñez de un barrio popular: el caso de Brisas del Volador en Bogotá

Este artículo explora las implicaciones socio-urbanas de la producción y transformación del espacio urbano en barrios informales o populares a partir de la experiencia de niños y niñas, para indagar sobre la construcción de significados en el barrio popular. Esto se realizó a partir de la revisión de los elementos que identifican como configuradores del entorno barrial, con relación a los factores que promueven o dificultan bienestar en esta población, tal y como esta población lo significa. La presente investigación se realizó en el barrio Brisas del Volador, dentro del marco del proyecto internacional sobre la experiencia de niños, niñas y adolescentes en las ciudades Growing up in cities iii, que es la tercera versión de un estudio original de Kevin Lynch en 1970, y una segunda versión de Louise Chawla en 1990. Se trabajó a partir de métodos participativos con los niños y niñas participes, y como resultado se reconocen procesos de uso, apropiación y significación del espacio urbano

Photocatalytic activation of peroxymonosulfate using ilmenite (FeTiO3) for Enterococcus faecalis inactivation

In this work, a raw and low cost mineral, ilmenite (FeTiO3), has been tested for the first time as a photocatalyst paired with peroxymonosulfate (HSO5-; PMS) for the inactivation of Enterococcus faecalis as an alternative to conventional treatments to disinfect wastewater for reuse. The influence of some operational parameters such as reagent dosage, catalyst concentration, initial pH, or flow rate was also studied and optimized. After several tests, the scarce pure photoactivity under UV-A was remarked by ilmenite because of its high iron content, which favors photogenerated charge recombination. However, ilmenite activity was highly promoted when combined with low concentrations of PMS and UV-A light, reaching total inactivation of Enterococcus faecalis in 120 min. Quenching tests were performed using methanol, tert-butyl alcohol, furfuryl alcohol, and Cu(II) to assess the main reactive species involved in the disinfection process determining the critical role of both HO·and SO4·- radicals in the process. Finally, the influence of the water matrix was also evaluated by studying the effect of water hardness and the presence of nutrients on the system. Overall, the PMS/Ilmenite/UV-A system yielded promising results with a total removal of Enterococcus faecalis in 120 min. However, it also showed the need for further study and understanding of the disinfection mechanism to achieve the same level of performance in real wastewaterPGM acknowledges Escuela Técnica Superior de Ingenieros Industriales (UPM) for the project ETSII-UPM20–03. SGR acknowledges UPM for the predoctoral contract granted within the ’Programa Propio’. JRC acknowledges Comunidad de Madrid for funding the research project IN_REUSE (APOYO-JOVENES-X5PKL6–88-KZ46KU), and also by the pluriannual agreement with the Polytechnic University of Madrid in the line of action Programme of Excellence for University Teaching Staf

Uniola paniculata (Poaceae, Chloridoideae, Unioliinae), nuevo registro para la flora de la Península de Yucatán, México

Background and Aims: The oat sea grass, Uniola paniculata, is distributed in the Caribbean, the United States of America and Mexico. The aim of this work is to report its occurrence and record in the state of Campeche, Mexico. Methods: Individuals of the family Poaceae were collected growing in a coastal dune in the southwest of the state of Campeche, particularly on the Isla del Carmen. The collections were processed and herborized for their conservation and classification. Key results: With the individuals’ identification and after reviewing its distribution, this is the first report of the presence of Uniola paniculata (Poaceae) on the Yucatan Peninsula, representing a contribution to the floristic knowledge of the region and the flora of Mexico. Conclusions: This species had only been reported from the coast of the Gulf of Mexico in the states of Tamaulipas, Veracruz and Tabasco. This record is relevant because of the ecological role of this oat sea grass in the coastal dunes.Antecedentes y Objetivos: La avena de mar, Uniola paniculata, se distribuye en el Caribe, los Estados Unidos de América y México. El objetivo de este trabajo es reportar su presencia y registro en el estado de Campeche, México. Métodos: Se colectaron ejemplares de la familia Poaceae creciendo en una duna frontal al suroeste del estado de Campeche, específicamente en la Isla del Carmen. Las colectas fueron procesadas y herborizadas, para su conservación e identificación. Resultado clave: Con la identificación de ejemplares, y después de hacer una revisión de su distribución, se registra por primera vez la presencia de Uniola paniculata (Poaceae) en la Península de Yucatán, representando una contribución al conocimiento florístico de la región y a la flora de México. Conclusiones: Esta especie solo había sido reportada para la costa del Golfo de México, en los estados de Tamaulipas, Veracruz y Tabasco. Este registro adquiere relevancia por el papel ecológico de este pasto en las dunas costeras

Propuesta estratégica de mejora en la implementación de los estándares mínimos del Sistema de Gestión de la Seguridad y Salud en el Trabajo (SG-SST) en la Empresa Hotel Casa Morales para el año 2020.

El presente trabajo muestra la importancia que cumple el sistema de gestión de seguridad y salud en el trabajo en una empresa y que normativas se requieren teniendo en cuenta la resolución 0312 de 2019 sobre los estándares mínimos y llevando una evaluación por medio de una matriz que permite identificar en que la empresa no está cumpliendo y accediendo a elaborar un plan anual y un diagrama de Gantt para la mejora de la problemática encontrada.This paper shows the importance of the occupational safety and health management system in a company and which regulations are required taking into account resolution 0312 of 2019 on minimum standards and carrying an evaluation through a matrix that allows to identify in which the company is not complying and agreeing to develop an annual plan and a Gantt chart for the improvement of the problems encountered

Electron Scattering from 1-Methyl-5-Nitroimidazole: Cross-Sections forModeling Electron Transport through Potential Radiosensitizers

In this study, we present a complete set of electron scattering cross-sections from 1-Methyl-5- Nitroimidazole (1M5NI) molecules for impact energies ranging from 0.1 to 1000 eV. This information is relevant to evaluate the potential role of 1M5NI as a molecular radiosensitizers. The total electron scattering cross-sections (TCS) that we previously measured with a magnetically confined electron transmission apparatus were considered as the reference values for the present analysis. Elastic scattering cross-sections were calculated by means of two different schemes: The Schwinger multichannel (SMC) method for the lower energies (below 15 eV) and the independent atom model-based screening-corrected additivity rule with interferences (IAM-SCARI) for higher energies (above 15 eV). The latter was also applied to calculate the total ionization cross-sections, which were complemented with experimental values of the induced cationic fragmentation by electron impact. Double differential ionization cross-sections were measured with a reaction microscope multi-particle coincidence spectrometer. Using a momentum imaging spectrometer, direct measurements of the anion fragment yields and kinetic energies by the dissociative electron attachment are also presented. Cross-sections for the other inelastic channels were derived with a self-consistent procedure by sampling their values at a given energy to ensure that the sum of the cross-sections of all the scattering processes available at that energy coincides with the corresponding TCS. This cross-section data set is ready to be used for modelling electron-induced radiation damage at the molecular level to biologically relevant media containing 1M5NI as a potential radiosensitizer. Nonetheless, a proper evaluation of its radiosensitizing effects would require further radiobiological experiments

Propuesta de una guía instructiva dirigida a la familia del paciente alcohólico

A retrospective and descriptive study with quanti and quality cross-sectional approach was conducted during the first quarter of 2015 with relatives of dependent alcoholic patients previously diagnosed on individual and group consultation belonging to “Capitán Roberto Fleites” Policlinic. The universe was composed by 579 families; the sample size was 25 families of alcoholic patients in the Group of mutual help of alcoholism. Two questionnaires were applied: one, created by the researcher and subject to an assessment according to the criteria of specialists, consisting of 16 closed questions; the second was the test to assess family functioning. Later it was made an instructive guide directed to family of alcoholic patient that contemplated, fundamentally, instructive aspects of orientation to report to what services to go in order to help these patients and their families. There was a predominance of family nuclearization and policy crisis like phase change between two stages and prevailed crisis by demoralization and the high incidence of family dysfunction and mechanism of family to face with drug dependency of touching the bottom or going to the root of the problem turned out to be predominant. The proposed of instructive guide was considered to be very adapted by a high per cent of consulted specialists.Se realizó un estudio descriptivo retrospectivo con enfoque cuanticualitativo de corte transversal durante el primer trimestre del año 2015 con familiares de pacientes alcohólicos dependientes previamente diagnosticados en consulta individual y grupal pertenecientes al Policlínico “Capitán Roberto Fleites”. El universo quedó constituido por 579 familias, el tamaño de la muestra fue de 25 familias de pacientes alcohólicos pertenecientes al Grupo de ayuda mutua de alcoholismo. Se aplicaron dos cuestionarios: el primero, creado por el investigador y sometido a una valoración según criterio de especialistas, constaba de 16 preguntas cerradas; el segundo fue la prueba para evaluar el funcionamiento familiar. Posteriormente se confeccionó una guía instructiva dirigida a la familia del paciente alcohólico que contempló, fundamentalmente, aspectos instructivos de orientación para informar a que servicios acudir para ayudar a estos enfermos y a sus familias. Hubo un predominio de la nuclearización familiar y de las crisis normativas como fase de cambio entre dos etapas y predominaron las crisis por desmoralización y la alta incidencia a la disfuncionalidad familiar y el mecanismo de afrontamiento familiar a la drogodependencia de tocar fondo o ir a la raíz del problema resultó ser predominante. La propuesta de guía instructiva fue considerada muy adecuada por un por ciento elevado de especialistas consultados. 

GHIA (Grupo de Herramientas Interactivas Avanzadas)

Es este documento se resumen las principales líneas actuales de investigación del grupo GHIA en lo que a informática educativa se refiere, así como su contexto y proyectos de futuro.This document summarizes the main research areas of GHIA regarding computer based learning, as well as its context and future work.En el momento actual, agradecemos su apoyo a los proyectos ASIES (TIN2010-17344) y Go-Lite (TIN2011-24139), financiados por el Ministerio de Educación, y al proyecto e-Madrid (S2009/TIC-1650), financiado por la Comunidad Autónoma de Madrid

Best Treatment Option for Patients With Refractory Aggressive B-Cell Lymphoma in the CAR-T Cell Era: Real-World Evidence From GELTAMO/GETH Spanish Groups

Real-world evidence comparing the efficacy of chimeric antigen receptor (CAR) T-cell therapy against that of the previous standard of care (SOC) for refractory large B-cell lymphoma (LBCL) is scarce. We retrospectively collected data from patients with LBCL according to SCHOLAR-1 criteria treated with commercial CAR T-cell therapy in Spain (204 patients included and 192 treated, 101 with axicabtagene ciloleucel [axi-cel], and 91 with tisagenlecleucel [tisa-cel]) and compared the results with a historical refractory population of patients (n = 81) obtained from the GELTAMO-IPI study. We observed superior efficacy for CAR-T therapy (for both axi-cel and tisa-cel) over pSOC, with longer progression-free survival (PFS) (median of 5.6 vs. 4-6 months, p <= 0.001) and overall survival (OS) (median of 15 vs. 8 months, p < 0.001), independently of other prognostic factors (HR: 0.59 (95% CI: 0.44-0.80); p < 0.001] for PFS, and 0.45 [(95% CI: 0.31-0.64)] for OS). Within the CAR-T cohort, axi-cel showed longer PFS (median of 7.3 versus 2.8 months, respectively, p = 0.027) and OS (58% versus 42% at 12 months, respectively, p = 0.048) than tisa-cel. These differences were maintained in the multivariable analysis. On the other hand, axi-cel was independently associated with a higher risk of severe cytokine release syndrome and neurotoxicity. Our results suggest that the efficacy of CAR-T cell therapy is superior to pSOC in the real-world setting. Furthermore, axi-cel could be superior in efficacy to tisa-cel, although more toxic, in this group of refractory patients according to SCHOLAR-1 criteria