172 research outputs found

    Public Libraries and the Internet 2006

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    Examines the capability of public libraries to provide and sustain public access Internet services and resources that meet community needs, including serving as the first choice for content, resources, services, and technology infrastructure

    Climate Change and Modelling of Extreme Temperatures in Switzerland

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    This study models maximum temperatures in Switzerland monitored in twelve locations using the Generalised Extreme Value (GEV) distribution. The parameters of the GEV distribution are determined within a Bayesian framework. We find that the parameters of the underlying distribution underwent a substantial change in the beginning of the 1980s. This change is characterised by an increase both in the level and the variability. We assess the likelihood of a heat wave of the Summer of 2003 using the fitted GEV distribution by accounting for the presence of a structural break. The estimation results do suggest that the heat wave of 2003 appears not that statistically improbable event as it is generally accepted in the relevant literature.Climate change, GEV, Bayesian modelling, Great Alpine Heat Wave

    Die kulturelle Einbettung des europäischen Marktes

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    In Anlehnung an Anthony Giddens wird zunächst eine Unterscheidung von Kultur und Gesellschaft entwickelt, welche auf dem Verhältnis von Regeln und Handlungen beruht. Dieses Verhältnis wird dann in der Realität von Märkten verfolgt. Besonderes Augenmerk wird dabei auf jene Marktprozesse gerichtet, in denen Kategorien von Waren konstituiert und verändert werden. Als Beispiel dient dabei der japanische Arbeitsmarkt, nicht zuletzt wegen der weltwirtschaftlichen Konstitution einer einheitlichen Ware Arbeitskraft im Zusammenhang der europäischen Integration untersucht. Es wird die These vertreten, daß sich in den europäischen Gesellschaften ein grundsätzlicher Wandel hinsichtlich des Verpflichtungscharakters der beruflichen Arbeit abzeichne - von der überkommenen Arbeitsmoral zu einer neuen durch hohe Grade der Autonomie gekennzeichneten "Berufsethik". (GF

    Agent-based dynamics in disaggregated growth models

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    This paper presents an agent-based model of disaggregated economic systems with endogenous growth features named Lagon GeneriC. This model is thought to represent a proof of concept that dynamically complete and highly disaggregated agent-based models allow to model economies as complex dynamical systems. It is used here for "theory generation", investigating the extension to a framework with capital accumulation of Gintis results on the dynamics of general equilibrium.Agent-based models, economic growth.

    Climate change and modelling of extreme temperatures in Switzerland

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    This study models maximum temperatures in Switzerland monitored in twelve locations using the generalised extreme value (GEV) distribution. The parameters of the GEV distribution are determined within a Bayesian framework. We find that the parameters of the underlying distribution underwent a substantial change in the beginning of the 1980s. This change is characterised by an increase both in the level and the variability. We assess the likelihood of the heat wave of the summer 2003 using the fitted GEV distribution by accounting for the presence of a structural break. The estimation results do suggest that the heat wave of 2003 is not that statistically improbable if an appropriate methodology is used for dealing with nonstationarit

    Agent-based dynamics in disaggregated growth models

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    URL des Documents de travail : http://centredeconomiesorbonne.univ-paris1.fr/bandeau-haut/documents-de-travail/Documents de travail du Centre d'Economie de la Sorbonne 2010.77 - ISSN : 1955-611XThis paper presents an agent-based model of disaggregated economic systems with endogenous growth features named Lagon GeneriC. This model is thought to represent a proof of concept that dynamically complete and highly disaggregated agent-based models allow to model economies as complex dynamical systems. It is used here for "theory generation", investigating the extension to a framework with capital accumulation of Gintis results on the dynamics of general equilibrium.On présente le modèle Lagon generiC : modèle multi-agent pourvu de caractéristiques de croissance endogène. Il s'agit d'un prototype hautement désagrégé et dynamiquement complet qui permet la représentation d'économies comme des systèmes dynamiques complexes. Une application aux résultats de Gintis sur la dynamique des prix est également présentée

    Mapping deliberation: calculation, articulation and intervention in the politics of organ transplantation

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    This paper reflects on the aims and outcomes of an innovative methodology of participatory technology appraisal, called Deliberative Mapping, which seeks to contribute to theoretical debates and practical experimentation around what it might mean to bring the technosciences into democracy. Deliberative Mapping is a hybrid methodology, involving both calculative and deliberative processes, which seeks to map the entanglements of biotechnological imbroglios, and translate these connections into the contexts of decision-making. Through application to the case study of organ transplantation, these procedures of calculation and articulation are critically examined, exploring their aim to reduce asymmetries between scientific, political, economic and other framings of the issue and their operation in contexts already complexly structured through existing power relations, which indicate the challenge of co-fabricating these experimental forms of intervention into political facts

    Progressive skin fibrosis is associated with a decline in lung function and worse survival in patients with diffuse cutaneous systemic sclerosis in the European Scleroderma Trials and Research (EUSTAR) cohort.

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    Objectives To determine whether progressive skin fibrosis is associated with visceral organ progression and mortality during follow-up in patients with diffuse cutaneous systemic sclerosis (dcSSc). Methods We evaluated patients from the European Scleroderma Trials and Research database with dcSSc, baseline modified Rodnan skin score (mRSS) ≥7, valid mRSS at 12±3 months after baseline and ≥1 annual follow-up visit. Progressive skin fibrosis was defined as an increase in mRSS >5 and ≥25% from baseline to 12±3 months. Outcomes were pulmonary, cardiovascular and renal progression, and all-cause death. Associations between skin progression and outcomes were evaluated by Kaplan-Meier survival analysis and multivariable Cox regression. Results Of 1021 included patients, 78 (7.6%) had progressive skin fibrosis (skin progressors). Median follow-up was 3.4 years. Survival analyses indicated that skin progressors had a significantly higher probability of FVC decline ≥10% (53.6% vs 34.4%; p<0.001) and all-cause death (15.4% vs 7.3%; p=0.003) than non-progressors. These significant associations were also found in subgroup analyses of patients with either low baseline mRSS (≤22/51) or short disease duration (≤15 months). In multivariable analyses, skin progression within 1 year was independently associated with FVC decline ≥10% (HR 1.79, 95% CI 1.20 to 2.65) and all-cause death (HR 2.58, 95% CI 1.31 to 5.09). Conclusions Progressive skin fibrosis within 1 year is associated with decline in lung function and worse survival in dcSSc during follow-up. These results confirm mRSS as a surrogate marker in dcSSc, which will be helpful for cohort enrichment in future trials and risk stratification in clinical practice
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