1,981 research outputs found
Shari\u27ah, Democracy, and the Modern Nation-State: Some Reflections on Islam, Popular Rule, and Pluralism
In this article, the author examines two considerations that are critical to a full and meaningful assessment of the degree to which Islam, and Islamic law in particular, can find authentic expressions of themselves under what may reasonably be considered a democratic form of government. The first of these has to do with the scope of Islamic law, or more properly, the scope of the interpretive authority of Muslim jurists, and whether a State that is governed by Shari‘ah must necessarily give priority to the views of religious scholars over those of all others in every aspect of life. Does establishing speed limits, formulating economic policy, or setting standards for medical licensing all fall under the legal authority of the jurists? If not, is there any basis other than political fiat upon which the scope of this jurisdiction might be defined? The second consideration is connected to the question of whether in contemplating the relationship between Islam and democracy, we have not conflated the framework within which modern democracy is packaged, namely the Nation-State (and some would insist on adding capitalism), with the spirit and essence of democratic rule. If we could imagine a State structure whose integrity was not equated with the ability to exercise an absolute monopoly over law-making and the concomitant imposition of a uniform standard of conduct on all of its citizens, would the idea of Islamic democracy present as many apparent difficulties as it presently does? The author’s objective is to add a dimension to the discussion on Islam and democracy that will render future assessments and proposals more nuanced and circumspect
Domestic Terrorism in the Islamic Legal Tradition
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72503/1/j.1478-1913.2001.tb03718.x.pd
Approximate Analytic Solution for the Spatiotemporal Evolution of Wave Packets undergoing Arbitrary Dispersion
We apply expansion methods to obtain an approximate expression in terms of
elementary functions for the space and time dependence of wave packets in a
dispersive medium. The specific application to pulses in a cold plasma is
considered in detail, and the explicit analytic formula that results is
provided. When certain general initial conditions are satisfied, these
expressions describe the packet evolution quite well. We conclude by employing
the method to exhibit aspects of dispersive pulse propagation in a cold plasma,
and suggest how predicted and experimental effects may be compared to improve
the theoretical description of a medium's dispersive properties.Comment: 17 pages, 4 figures, RevTe
The roles of motivation and ability in controlling the consequences of stereotype suppression
Two experiments investigated the conditions under which previously suppressed stereotypes are applied in impression formation. In Experiment 1, the extent to which a previously suppressed racial stereotype influenced subsequent impressions depended on the race of the target who was subsequently encountered. Whereas impressions of race-unspecified targets were assimilated to the stereotype following its suppression, no such effects were observed when the target belonged to the racial group whose stereotype had been initially suppressed. These results demonstrate that when perceivers are motivated to avoid stereo-typing individuals, the influence of a stereotype that has been previously activated through suppression is minimized. Experiment 2 demonstrated that these processing goals effectively reduce the impact of suppression-activated stereotypes only when perceivers have sufficient capacity to enact the goals. These results suggest that both sufficient motivation and capacity are necessary to prevent heightened stereotyping following stereotype suppression
Mimicking the electron transfer chain in photosystem II with a molecular triad thermodynamically capable of water oxidation
In the photosynthetic photosystem II, electrons are transferred from the manganese-containing oxygen evolving complex (OEC) to the oxidized primary electron-donor chlorophyll P680•+ by a proton-coupled electron transfer process involving a tyrosine-histidine pair. Proton transfer from the tyrosine phenolic group to a histidine nitrogen positions the redox potential of the tyrosine between those of P680•+ and the OEC. We report the synthesis and time-resolved spectroscopic study of a molecular triad that models this electron transfer. The triad consists of a high-potential porphyrin bearing two pentafluorophenyl groups (PF10), a tetracyanoporphyrin electron acceptor (TCNP), and a benzimidazole-phenol secondary electron-donor (Bi-PhOH). Excitation of PF10 in benzonitrile is followed by singlet energy transfer to TCNP (Ï„ = 41 ps), whose excited state decays by photoinduced electron transfer (Ï„ = 830 ps) to yield Bi-PhOH-PF 10•+-TCNP•-. A second electron transfer reaction follows (Ï„ < 12 ps), giving a final state postulated as BiH+-PhO•-PF10-TCNP•-, in which the phenolic proton now resides on benzimidazole. This final state decays with a time constant of 3.8 μs. The triad thus functionally mimics the electron transfers involving the tyrosine-histidine pair in PSII. The final charge-separated state is thermodynamically capable of water oxidation, and its long lifetime suggests the possibility of coupling systems such as this system to water oxidation catalysts for use in artificial photosynthetic fuel production.Fil: Megiatto, Jackson D.. Arizona State University; Estados UnidosFil: Antoniuk Pablant, Antaeres. Arizona State University; Estados UnidosFil: Sherman, Benjamin D.. Arizona State University; Estados UnidosFil: Kodis, Gerdenis. Arizona State University; Estados UnidosFil: Gervaldo, Miguel Andres. Universidad Nacional de RÃo Cuarto; Argentina. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - Córdoba; ArgentinaFil: Moore, Thomas A.. Arizona State University; Estados UnidosFil: Moore, Ana L.. Arizona State University; Estados UnidosFil: Gust, Devens. Arizona State University; Estados Unido
Salbutamol for analgesia in renal colic : study protocol for a prospective, randomised, placebo-controlled phase II trial (SARC)
Background
Renal colic is the pain experienced by a patient when a renal calculus (kidney stone) causes partial or complete obstruction of part of the renal outflow tract. The standard analgesic regimes for renal colic are often ineffective; in some studies, less than half of patients achieve complete pain relief, and a large proportion of patients require rescue analgesia within 4 h. Current analgesic regimes are also associated with significant side effects including nausea, vomiting, drowsiness and respiratory depression. It has been hypothesised that beta adrenoreceptor agonists, such as salbutamol, may reduce the pain of renal colic. They have been shown to impact a number of factors that target the physiological causes of pain in renal colic (ureteric spasm and increased peristalsis, increased pressure at the renal pelvis and prostaglandin release with inflammation). There is biological plausibility and a body of evidence sufficient to suggest that this novel treatment for the pain of renal colic should be taken to a phase II clinical trial. The aim of this trial is to test whether salbutamol is an efficacious analgesic adjunct when added to the standard analgesic regime for patients presenting to the ED with subsequently confirmed renal colic.
Methods
A phase II, randomised, placebo-controlled trial will be performed in an acute NHS Trust in the East Midlands. Patients presenting to the emergency department with pain requiring IV analgesia and working diagnosis of renal colic will be randomised to receive standard analgesia ± a single intravenous injection of Salbutamol. Secondary study objectives will explore the feasibility of conducting a larger, phase III trial.
Discussion
The trial will provide important information about the efficacy of salbutamol as an analgesic adjunct in renal colic. It will also guide the development of a definitive phase III trial to test the cost and clinical effectiveness of salbutamol as an analgesic adjunct in renal colic. Salbutamol benefits from widespread use across the health service for multiple indications, extensive staff familiarity and a good side effect profile; therefore, its potential use for pain relief may have significant benefits for patient care.
Trial registration
ISRCTN Registry ISRCTN14552440. Registered on 22 July 201
Stabilization of Deterministically Chaotic Systems by Interference and Quantum Measurements: The Ikeda Map Case
We propose a method which can effectively stabilize fixed points in the
classical and quantum dynamics of a phase-sensitive chaotic system with
feedback. It is based on feeding back a selected quantum sub-ensemble whose
phase and amplitude stabilize the otherwise chaotic dynamics. Although the
method is rather general, we apply it to realizations of the inherently chaotic
Ikeda map. One suggested realization involves the Mach-Zender interferometer
with Kerr nonlinearity. Another realization involves a trapped ion interacting
with laser fields.Comment: RevTeX, 5 pages, two figure
The mating-specific Gα interacts with a kinesin-14 and regulates pheromone-induced nuclear migration in budding yeast
As a budding yeast cell elongates toward its mating partner, cytoplasmic microtubules connect the nucleus to the cell cortex at the growth tip. The Kar3 kinesin-like motor protein is then thought to stimulate plus-end depolymerization of these microtubules, thus drawing the nucleus closer to the site where cell fusion and karyogamy will occur. Here, we show that pheromone stimulates a microtubule-independent interaction between Kar3 and the mating-specific Gα protein Gpa1 and that Gpa1 affects both microtubule orientation and cortical contact. The membrane localization of Gpa1 was found to polarize early in the mating response, at about the same time that the microtubules begin to attach to the incipient growth site. In the absence of Gpa1, microtubules lose contact with the cortex upon shrinking and Kar3 is improperly localized, suggesting that Gpa1 is a cortical anchor for Kar3. We infer that Gpa1 serves as a positional determinant for Kar3-bound microtubule plus ends during mating. © 2009 by The American Society for Cell Biology
Aeolian dynamics of beach scraped ridge and dyke structures
Where urban areas are situated close to a beach, sand dunes act as protection from flooding and erosion.When a
dune has been removed or damaged by erosion, dune, ridge or dyke re-building using heavymachinery, a process
known as beach scraping, is a common method of restoration. Following construction, natural accretion of sediment
on the backshore is preferable as it facilitates sustained natural dune building, growth of vegetation, and
habitat creation and reduces the need for further beach scraping.
This study investigates the near surface flowand transport potential for three artificial structure designs: a single
ridge, a double ridge and a dyke. The three shapes contained an identical volume of sand and were preceded by
50mof beach at an angle of 3°. A computational fluid dynamic model (CFD)was created for each scenario to calculatewind
flowand shear velocity from 4 differentwind directions at 22.5° intervals from 0° (onshore) to 67.5°.
From this data sediment flux was predicted along a two dimensional transect for each of the scenarios.
For all structures, shear velocity on the beach and stoss slope decreased as incident wind direction became more
oblique; conversely shear velocity in the lee of the crest increased. A reduction in shear velocity at the foot of each
structure also occurred and appears related to stoss slope,with the greatest reduction at the toe of the dyke structure
(stoss slope 34°) and the least before the single ridge (stoss slope 17°).
Specifically the results suggest that the double ridge structure is the most resilient to aeolian erosion. Shear velocity
reduction on the back beach is comparable to the dyke and sediment flux fromthe stoss slope of the double
ridge structure may become trapped in the swale between the two ridges encouraging sediment deposition, thus
reducing sediment transport beyond the dunes and backshore. Although the dyke structure underwent the
greatest reduction in shear velocity on the back beach it experienced substantial sediment flux at the crest and
along the top of the structure, making it susceptible to erosion during a strongwind event. The highest sediment
transport rate was calculated at the crest of the single ridge, and the single ridge structure also created the
smallest reduction of shear velocity on the back beach, thus making it less desirable than the double ridge
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