Basin-wide warming of the Indian Ocean during El Nino and Indian Ocean dipole years

Basin-wide wintertime surface warming is observed in the Indian Ocean during El Niño years. The basin-wide warming is found to be stronger when El Niño and Indian Ocean Dipole (IOD) co-occur. The mechanisms responsible for the basin-wide warming are different for the years with El Niño only (El Niño without IOD) and for the co-occurrence (both El Niño and IOD) years. Strong westward propagation of downwelling Rossby waves is observed in the southern Indian Ocean during the IOD years. Such strong propagation is not seen in the case of the El Niño-only years. This indicates that the ocean dynamics play an important role in winter warming of the western Indian Ocean during the IOD years. The weak easterly wind anomalies in the El Niño-only years show no measurable impact on the Wyrtki Jets, but weakening or reversal of these jets is seen in the IOD years. This strongly suggests that the variability related to surface circulation is due to the local IOD forcing rather than El Niño induced wind anomaly. For the El Niño-only composites, surface heat fluxes (mainly latent heat flux and short wave radiation) play an important role in maintaining the basin-wide surface warming in the Indian Ocean. In the IOD-only composites (when there is no El Niño in the Pacific), such basin-wide warming is not seen because of the absence of ENSO (El Niño and Southern Oscillation) induced subsidence over the eastern Indian Ocean. For the years in which both El Niño in the Pacific and dipole in the Indian Ocean co-occur, warming in the western Indian Ocean is due to the ocean dynamics and that in the eastern Indian Ocean is due to the anomalous latent heat flux and solar radiation

Indian Ocean dipole mode events in a simple mixed layer ocean model

A precise knowledge of sea surface temperature (SST) is very essential for climate and oceanographic studies. In this paper a simple two dimensional mixed layer ocean model and its numerical code have been developed and used to simulate the SST fields over the north Indian Ocean (20°S-25°N and 35°E-115°Î) for a period of 10 years (1992-2001). The model simulated the SST variability reasonably well. The simple model could simulate the observed dipole of 1997 and 1994 very well, especially the eastern cooling. The model study showed that the interannual SST variability in the western equatorial Indian Ocean is not only due to the variability in the surface heat fluxes, but also due to the variability in wind and sea surface height (SSH). The OLR anomaly also shows positive (negative) anomaly over the negative (positive) anomalous SST region. The variability in the latent heat flux is found to be greatly influencing the SST variability in the eastern equatorial Indian Ocean

Representation of Bay of Bengal upper-ocean salinity in general circulation models

The Bay of Bengal (BoB) upper-ocean salinity is examined in the National Centers for Environmental Prediction-Climate Forecasting System version 2 (CFSv2) coupled model, Modular Ocean Model version 5 (MOM5), and Indian National Centre for Ocean Information Services Global Ocean Data Assimilation System (INC-GODAS). CFSv2 displays a large positive salinity bias with respect to World Ocean Atlas 2013 in the upper 40 m of the water column. The prescribed annual mean river discharge and excess evaporation are the main contributors to the positive bias in surface salinity. Overestimation of salinity advection also contributes to the high surface salinity in the model during summer. The surface salinity bias in MOM5 is smaller than in CFSv2 due to prescribed local freshwater flux and seasonally varying river discharge. However, the bias is higher around 70 m in summer and 40 m in fall. This bias is attributed to excessive vertical mixing in the upper ocean. Despite the fact that representation of salinity in INC-GODAS is more realistic due to data assimilation, the vertical mixing scheme still imposes systematic errors. The small-scale processes that control oceanographic turbulence are not adequately resolved in any of these models. Better parameterizations based on dedicated observational programs may help improve freshwater representation in regional and global models

El Niño Modulations Over The Past Seven Centuries (Letter to the editor)

postprin

Advanced Technologies for Oral Controlled Release: Cyclodextrins for oral controlled release

Cyclodextrins (CDs) are used in oral pharmaceutical formulations, by means of inclusion complexes formation, with the following advantages for the drugs: (1) solubility, dissolution rate, stability and bioavailability enhancement; (2) to modify the drug release site and/or time profile; and (3) to reduce or prevent gastrointestinal side effects and unpleasant smell or taste, to prevent drug-drug or drug-additive interactions, or even to convert oil and liquid drugs into microcrystalline or amorphous powders. A more recent trend focuses on the use of CDs as nanocarriers, a strategy that aims to design versatile delivery systems that can encapsulate drugs with better physicochemical properties for oral delivery. Thus, the aim of this work was to review the applications of the CDs and their hydrophilic derivatives on the solubility enhancement of poorly water soluble drugs in order to increase their dissolution rate and get immediate release, as well as their ability to control (to prolong or to delay) the release of drugs from solid dosage forms, either as complexes with the hydrophilic (e.g. as osmotic pumps) and/ or hydrophobic CDs. New controlled delivery systems based on nanotechonology carriers (nanoparticles and conjugates) have also been reviewed

Herpesvirus Glycoproteins Undergo Multiple Antigenic Changes before Membrane Fusion

Herpesvirus entry is a complicated process involving multiple virion glycoproteins and culminating in membrane fusion. Glycoprotein conformation changes are likely to play key roles. Studies of recombinant glycoproteins have revealed some structural features of the virion fusion machinery. However, how the virion glycoproteins change during infection remains unclear. Here using conformation-specific monoclonal antibodies we show in situ that each component of the Murid Herpesvirus-4 (MuHV-4) entry machinery—gB, gH/gL and gp150—changes in antigenicity before tegument protein release begins. Further changes then occurred upon actual membrane fusion. Thus virions revealed their final fusogenic form only in late endosomes. The substantial antigenic differences between this form and that of extracellular virions suggested that antibodies have only a limited opportunity to block virion membrane fusion

Vampires in the village Žrnovo on the island of Korčula: following an archival document from the 18th century

Središnja tema rada usmjerena je na raščlambu spisa pohranjenog u Državnom arhivu u Mlecima (fond: Capi del Consiglio de’ Dieci: Lettere di Rettori e di altre cariche) koji se odnosi na događaj iz 1748. godine u korčulanskom selu Žrnovo, kada su mještani – vjerujući da su se pojavili vampiri – oskvrnuli nekoliko mjesnih grobova. U radu se podrobno iznose osnovni podaci iz spisa te rečeni događaj analizira u širem društvenom kontekstu i prate se lokalna vjerovanja.The main interest of this essay is the analysis of the document from the State Archive in Venice (file: Capi del Consiglio de’ Dieci: Lettere di Rettori e di altre cariche) which is connected with the episode from 1748 when the inhabitants of the village Žrnove on the island of Korčula in Croatia opened tombs on the local cemetery in the fear of the vampires treating. This essay try to show some social circumstances connected with this event as well as a local vernacular tradition concerning superstitions

Indian summer monsoon intra-seasonal oscillation associated with the developing and decaying phase of El Nino

The present study investigates the characteristics of active and break cycles associated with the Indian summer monsoon (ISM) during developing and decaying phase of El Niño and in the years in which Indian Ocean Dipole (IOD) co-occurred with El Niño (co-occurred years). Observations show that break days are more in number (∼2–3 times) and long lasting (∼15–20 days) than active days in El Niño developing summers and vice versa for decay years. During El Niño developing years, northward propagation is well organized with significant anomalies in both active and break phases. The increased convection associated with active phase persists longer over Indian Ocean, than over the monsoon region, while the reduced convection in break phase propagates faster from ocean to land and persists there for a longer time. Compared to break events, active events have slower (faster) propagation over the monsoon (oceanic) region during El Nino decay years. The present study put forward the argument that the contrasting persistent circulations over Indo-western Pacific regions favour particular phase of intra-seasonal oscillation (ISO) in developing and decay phase of El Nino. These long-lasting circulations advect anomalous dry (moist) air to ISM region for longer period, resulting in long-lasting break (active) events in El Niño developing (decay) years. During co-occurrence years, the number of break (active) days is reduced by two to three times compared to the developing (decaying) phase of El Niño. It is found that 30- to 60-day scale ISO is strongly modulated, than 10 - to 20-day scale, by the changes in seasonal mean state associated with El Nino. Thus, this study demonstrates that the ISO characteristics such as its variance, northward propagation, spatial distribution and duration of active and break days are strongly modulated by seasonal background anomalies over the Indo-Pacific region

Role of thermocline-SST coupling in the evolution of IOD events and their regional impacts

The evolution of sea surface temperature (SST) and thermocline (represented by 20 °C isotherm depth, D20) in the east equatorial Indian Ocean (EIO) associated with the Indian Ocean Dipole (IOD) years is studied for the period of 50 years from 1958 to 2007. A new IOD index based on combined anomalies of surface winds, D20 and SST over the equatorial Indian Ocean is defined to identify strong and weak IOD events. It is found that the evolution of strong IOD events is driven by ocean dynamics in the form of thermocline-SST coupling and is strongly interactive with the atmosphere, whereas the weak IOD events are mere response to surface winds without such dynamical coupling. The easterly wind anomalies extend up to the western equatorial Indian Ocean (WIO) during strong IOD years and support enhanced EIO air-sea interactions. On the other hand, the evolution of zonal wind anomalies is weak during the weak IOD years. Thermocline-SST coupling is robust in both EIO and WIO during strong IOD years, which is primarily responsible for the enhanced SST gradient, strong enough to establish anomalous Walker circulation within the Indian Ocean. The strong convection over the WIO associated with the Indian Ocean Walker cell triggers a secondary cell with subsidence over the African landmass. This double cell structure over the equatorial Indian Ocean is not reported before. Such double cell structure is not evident in weak IOD years and instead the convection over WIO extends up to African landmass. These are well supported by the spatial pattern of anomalous precipitable water during strong and weak IOD years. Strengthening of monsoon flow and local Hadley cell associated with strong IOD events enhances precipitation over the Indian subcontinent, whereas weak IOD years have less impact on the Indian summer monsoon circulation and rainfall. Analysis reveals that the EIO thermocline index and combined index could be potential predictors for the central Indian rainfall during summer