164 research outputs found

    Mammography-based screening program: preliminary results from a first 2-year round in a Brazilian region using mobile and fixed units

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    RLH, TBS and ALF made substantial contributions to the conception and design of the article, the acquisition, analysis and interpretation of the data, and drafting of the article. ECM, JSCM and NB made substantial contributions to the conception and design of the study.Background: Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer deaths among women worldwide. The use of mobile mammography units to offer screening to women living in remote areas is a rational strategy to increase the number of women examined. This study aimed to evaluate results from the first 2 years of a government-organized mammography screening program implemented with a mobile unit (MU) and a fixed unit (FU) in a rural county in Brazil. The program offered breast cancer screening to women living in Barretos and the surrounding area. Methods: Based on epidemiologic data, 54 238 women, aged 40 to 69 years, were eligible for breast cancer screening. The study included women examined from April 1, 2003 to March 31, 2005. The chi-square test and Bonferroni correction analyses were used to evaluate the frequencies of tumors and the importance of clinical parameters and tumor characteristics. Significance was set at p < 0.05. Results: Overall, 17 964 women underwent mammography. This represented 33.1% of eligible women in the area. A mean of 18.6 and 26.3 women per day were examined in the FU and MU, respectively. Seventy six patients were diagnosed with breast cancer (41 (54%) in the MU). This represented 4.2 cases of breast cancer per 1000 examinations. The number of cancers detected was significantly higher in women aged 60 to 69 years than in those aged 50 to 59 years (p < 0.001) or 40 to 49 years (p < 0.001). No difference was observed between women aged 40 to 49 years and those aged 50 to 59 years (p = 0.164). The proportion of tumors in the early (EC 0 and EC I) and advanced (CS III and CS IV) stages of development were 43.4% and 15.8%, respectively. Conclusions: Preliminary results indicate that this mammography screening program is feasible for implementation in a rural Brazilian territory and favor program continuation

    Brainstem abscess of undetermined origin: microsurgical drainage and brief antibiotic therapy

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    CONTEXTO:Abscessos isolados do tronco encefálico são raros e geralmente associados a outras infecções. Trata-se de condição grave, com grande morbidade e mortalidade. Opções cirúrgicas são aspiração com estereotaxia e drenagem microcirúrgica. Antibioticoterapia sistêmica tem sido usada por mais de seis semanas.RELATO DE CASO:Apresentamos o caso de um jovem com abscesso pontino sem outras infecções sistêmicas. O paciente foi tratado com drenagem microcirúrgica e antibioticoterapia por três semanas. Houve boa evolução pós-operatória.CONCLUSÕES:Acesso microcirúrgico pode ser considerado uma opção importante no tratamento de grandes abscessos do tronco encefálico, que são multiloculados, próximos da superfície ou que contenham líquido espesso. Drenagem completa do material purulento pode diminuir o período de antibioticoterapia.CONTEXT:Solitary brainstem abscesses are rare and they are usually associated with other infections. They are severe conditions with high morbidity and mortality. The surgical options are stereotactic aspiration and microsurgical drainage. Systemic antibiotic therapy is used for more than six weeks.CASE REPORT:We present the case of a young man with a solitary abscess at the pons, without other systemic infections. The patient was treated by means of microsurgical drainage and antibiotic therapy for three weeks. His postoperative recovery was good.CONCLUSIONS:A microsurgical approach may be considered to be an important option for large abscesses that are multiloculated, close to the surface or contain thick fluid. Complete emptying of the purulent accumulation may diminish the required duration of antibiotic therapy.Universidade Estadual Paulista Faculdade de Medicina de Botucatu Department of Neurology, Psychology and PsychiatryUniversidade Estadual Paulista Faculdade de Medicina de Botucatu Department of Neurology, Psychology and Psychiatr

    Electromagnetic fields at the sea bottom induced by a line of immersed electric dipoles

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    The analysis of electromagnetic fields caused by alternate or transient electric currents flowing along a cable in sea water has several applications. It supports the interpretation of electromagnetic geophysical data and safety procedures against the threat of sea mines. The approach to the problem employs a magnetic vector potential in the frequency domain due to a pulse source electric dipole, and performs Laplace and Hankel transforms and integration along the cable, to describe the variation of the magnetic induction field due to an electric dipole of finite length. The result is applicable to shallow or deep sea water environments, adaptable to any transmitting current waveform and useful for wave-field separation. The prospects relate to a horizontal receiving coil at the sea bottom and simulate: a minesweeper campaign with a current source at the sea surface or a geophysical survey with a current source close to the sea floor. Therefore, the present analysis may serve: to define parameters in counter-sweeping of submarine mines; to map the conductivity of sediments under shallow waters for the prevention and control of contamination; and as a first approach in the characterization of offshore mineral and oil economic deposits.A análise de campos eletromagnéticos causados por correntes alternadas ou transientes fluindo ao longo de um cabo na água do mar tem várias aplicações. Ela prove suporte à interpretação de dados geofísicos eletromagnéticos e aos procedimentos de segurança contra a ameaça de minas submarinas. A abordagem do problema emprega um potencial vetorial magnético, no domínio da frequência, devido a um dipolo elétrico com uma fonte tipo pulso e calcula transformações de Laplace e de Hankel e integração ao longo do comprimento do cabo, para descrever a variação temporal do campo magnético de indução devido a um dipolo elétrico de comprimento finito. O resultado é aplicável em ambientes de água do mar rasa ou profunda, adaptável para qualquer forma de onda de corrente transmitida e útil para separação de campos de ondas. As configurações se referem a uma bobina receptora horizontal no fundo do mar e simulam: uma campanha de varredura de minas submarinas com uma fonte de corrente na superfície ou um levantamento geofísico com uma fonte de corrente próxima ao assoalho do mar. Portanto, a presente análise pode servir: para definir parâmetros em contra-varredura de minas submarinas; para mapear a condutividade de sedimentos sob águas rasas em prevenção e controle de contaminação e como uma primeira abordagem na caracterização de depósitos minerais e de hidrocarbonetos no mar

    Signals in the Soil: Underground Antennas

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    Antenna is a major design component of Internet of Underground Things (IOUT) communication system. The use of antenna, in IOUT, differs from traditional communication in that it is buried in the soil. Therefore, one of the main challenges, in IOUT applications, is to establish a reliable communication. To that end, there is a need of designing an underground-specific antenna. Three major factors that can impact the performance of a buried antenna are: (1) effect of high soil permittivity changes the wavelength of EM waves, (2) variations in soil moisture with time affecting the permittivity of the soil, and (3) difference in how EM waves propagate during aboveground (AG) and underground (UG) communications. For the third challenge above, it is to be noted that lateral waves are dominant component in EM during UG2UG communication and suffer lowest attenuation as compared to other, direct and reflected, components. Therefore, antennas used for over-the-air (OTA) communication will not be suitable for UG communication because of impedance mismatch. This chapter focuses on developing a theoretical model for understanding the impact of soil on antenna by conducting experiments in different soil types (silty clay loam, sandy, and silt loam soil) and indoor testbed. The purpose of the model is to predict UG antenna resonance for designing efficient communication system for IOUT. Based on the model a wideband planar antenna is designed considering soil dispersion and soil–air interface reflection effect which improves the communication range five times from the antennas designed only for the wavelength change in soil. Furthermore, it also focuses on developing an impedance model to study the effect of changing wavelength in underground communication. It is also discussed how soil–air interface and soil properties effect the return loss of dipole antenna

    Signals in the Soil: An Introduction to Wireless Underground Communications

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    In this chapter, wireless underground (UG) communications are introduced. A detailed overview of WUC is given. A comprehensive review of research challenges in WUC is presented. The evolution of underground wireless is also discussed. Moreover, different component of UG communications is wireless. The WUC system architecture is explained with a detailed discussion of the anatomy of an underground mote. The examples of UG wireless communication systems are explored. Furthermore, the differences of UG wireless and over-the-air wireless are debated. Different types of wireless underground channel (e.g., In-Soil, Soil-to-Air, and Air-to-Soil) are reported as well

    Revival of the Magnetar PSR J1622–4950: Observations with MeerKAT, Parkes, XMM-Newton, Swift, Chandra, and NuSTAR

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    © 2018. The American Astronomical Society.. New radio (MeerKAT and Parkes) and X-ray (XMM-Newton, Swift, Chandra, and NuSTAR) observations of PSR J1622-4950 indicate that the magnetar, in a quiescent state since at least early 2015, reactivated between 2017 March 19 and April 5. The radio flux density, while variable, is approximately 100 larger than during its dormant state. The X-ray flux one month after reactivation was at least 800 larger than during quiescence, and has been decaying exponentially on a 111 19 day timescale. This high-flux state, together with a radio-derived rotational ephemeris, enabled for the first time the detection of X-ray pulsations for this magnetar. At 5%, the 0.3-6 keV pulsed fraction is comparable to the smallest observed for magnetars. The overall pulsar geometry inferred from polarized radio emission appears to be broadly consistent with that determined 6-8 years earlier. However, rotating vector model fits suggest that we are now seeing radio emission from a different location in the magnetosphere than previously. This indicates a novel way in which radio emission from magnetars can differ from that of ordinary pulsars. The torque on the neutron star is varying rapidly and unsteadily, as is common for magnetars following outburst, having changed by a factor of 7 within six months of reactivation

    Early Days of Food and Environmental Virology

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