218 research outputs found
A nativist divide? Anti-immigration attitudes and diffuse support for democracy in Western Europe
Earlier research has shown a strong connection between anti-immigration attitudes and political trust in Western Europe. In this research note, we examine if nativists’ low levels of specific political support translate into a more general scepticism about democracy as a system of government. Using comparative data from the European Social Survey (ESS) and the European Values Study (EVS), we investigate the relationship between nativist attitudes and several indicators of principled, or diffuse, support for democracy. The findings testify to a nativist divide in diffuse political support. We find a systematic and significant difference in support for democracy between strong nativists and other citizens. West European nativists are less likely than other citizens to view their country as democratic. They also tend to perceive living in a democracy as less important than people with a more positive outlook on immigrants. Moreover, and maybe more worrying, nativists express lower levels support for democracy in relation to non-democratic regime alternatives, that is, they are less likely to be “principled” democrats. The found negative associations remain also after controlling for nativists’ levels of specific support, which indicates that there may be a more fundamental opposition between nativism and diffuse support for democracy than previously acknowledged. We believe that these findings have important implications for research trying to understand challenges to liberal democracy in a time when nativist parties have been successful in politicizing immigration and continue to score electoral victories all over Europe.publishedVersio
Nativist attitudes and opportunistic support for democracy
Do nativists differ from other citizens in their attitudes towards democracy? In this article it is demonstrated that nativism goes hand in hand with preferences for a type of democracy where the interests of the natives should prevail, even at the cost of diminished minority rights, checks and balances, and other constraints on executive power. Liberal representative democracy is not for nativists. It is also shown that nativists seem to believe that the end justifies the means when it comes to different forms of decision making, and that this opportunistic trait usually translates into support for more direct democracy and scepticism towards representative democracy, because nativists tend to believe that they are in the majority (even if they are not). This article concludes that this tendency may in fact be a blessing of sorts, as it keeps nativists from supporting alternatives to democracy.publishedVersio
How Populism and Polarization Affect Europe’s Liberal Democracies
In recent years, two phenomena have put Europe’s liberal democracies under strain: populism and polarization. The rise of populist parties, the increasing radicalization of publics and political discourse, as well as the expansion of hyperpartisan media have caused concern among observers and citizens alike. While lively academic discussions have revolved around the causes of these phenomena, research regarding their real-world consequences has been sparse. This thematic issue wants to address this gap in the literature and contribute to developing strategies for mitigating potential threats populism and polarization may pose to liberal democracies. To this end, it examines how populism and polarization affect citizens across Europe. It links research on audiences of hyperpartisan media with work on elite-induced polarization, populist conceptions of democracy, election results and support for the democratic system, and policy-making by populist governments
How Populism and Polarization Affect Europe's Liberal Democracies
In recent years, two phenomena have put Europe's liberal democracies under strain: populism and polarization. The rise of populist parties, the increasing radicalization of publics and political discourse, as well as the expansion of hyperpartisan media have caused concern among observers and citizens alike. While lively academic discussions have revolved around the causes of these phenomena, research regarding their real-world consequences has been sparse. This thematic issue wants to address this gap in the literature and contribute to developing strategies for mitigating potential threats populism and polarization may pose to liberal democracies. To this end, it examines how populism and polarization affect citizens across Europe. It links research on audiences of hyperpartisan media with work on elite-induced polarization, populist conceptions of democracy, election results and support for the democratic system, and policy-making by populist governments
Do Polls Influence Opinions? Investigating Poll Feedback Loops Using the Novel Dynamic Response Feedback Experimental Procedure
Opinion polls may inadvertently affect public opinion, as people may change their attitudes after learning what others think. A disconcerting possibility is that opinion polls have the ability to create information cascades, wherein the majority opinion becomes increasingly larger over time. Testing poll influence on attitudes toward Syrian refugees and mandatory measles vaccination, we field survey experiments on a probability-based online survey panel. Through a novel automated procedure labeled the dynamic response feedback, we measure whether the answers from early poll respondents can influence the opinions of subsequent respondents who learn the answers of the previous respondents. Using this procedure, no feedback loops are identified.publishedVersio
Retinoic acid has different effects on UCP1 expression in mouse and human adipocytes
BACKGROUND: Increased adipose thermogenesis is being considered as a strategy aimed at preventing or reversing obesity. Thus, regulation of the uncoupling protein 1 (UCP1) gene in human adipocytes is of significant interest. Retinoic acid (RA), the carboxylic acid form of vitamin A, displays agonist activity toward several nuclear hormone receptors, including RA receptors (RARs) and peroxisome proliferator-activated receptor δ (PPARδ). Moreover, RA is a potent positive regulator of UCP1 expression in mouse adipocytes. RESULTS: The effects of all-trans RA (ATRA) on UCP1 gene expression in models of mouse and human adipocyte differentiation were investigated. ATRA induced UCP1 expression in all mouse white and brown adipocytes, but inhibited or had no effect on UCP1 expression in human adipocyte cell lines and primary human white adipocytes. Experiments with various RAR agonists and a RAR antagonist in mouse cells demonstrated that the stimulatory effect of ATRA on UCP1 gene expression was indeed mediated by RARs. Consistently, a PPARδ agonist was without effect. Moreover, the ATRA-mediated induction of UCP1 expression in mouse adipocytes was independent of PPARγ coactivator-1α. CONCLUSIONS: UCP1 expression is differently affected by ATRA in mouse and human adipocytes. ATRA induces UCP1 expression in mouse adipocytes through activation of RARs, whereas expression of UCP1 in human adipocytes is not increased by exposure to ATRA
Thinking out of the box? A content analysis of the response to published research on the effects of remote, retroactive intercessory prayer
A content analysis of the rapid email responses to a potentially controversial article published in the British Medical Journal (BMJ) on the effect of remote, retroactive intercessory prayer on a group of patients with bloodstream infection at a university hospital in Israel was performed. The content analysis revealed 12 main themes, of which the most predominant were negative and relating to methodological concerns or comments, and/or were religious in nature, often with direct reference to God. Further responses were of a satirical nature, mocking the study. It is concluded that perhaps the real strength of the paper lies not in the results of the study itself, but in the challenge to what constitutes conventional wisdom and the encouragement to readers of the BMJ to Think out of the box
Cross polarization from H-1 to quadrupolar Li-6 nuclei for dissolution DNP
Cross polarization from protons to quadrupolar Li-6 nuclei is combined with dynamic nuclear polarization of protons at 1.2 K and 6.7 T using TEMPOL as a polarizing agent followed by rapid dissolution. Compared to direct Li-6 DNP without cross-polarization, a higher nuclear spin polarization P(Li-6) can be obtained in a shorter time. A double resonance H-1-Li-6 probe was designed that is equipped for Longitudinally Detected Electron Spin Resonance
Comparison of veterinary drugs and veterinary homeopathy: part 1
For many years after its invention around 1796, homeopathy was widely used in people and later in animals. Over the intervening period (1796-2016) pharmacology emerged as a science from Materia Medica (medicinal materials) to become the mainstay of veterinary therapeutics. There remains today a much smaller, but significant, use of homeopathy by veterinary surgeons. Homeopathic products are sometimes administered when conventional drug therapies have not succeeded, but are also used as alternatives to scientifically based therapies and licensed products. The principles underlying the veterinary use of drug-based and homeopathic products are polar opposites; this provides the basis for comparison between them. This two-part review compares and contrasts the two treatment forms in respect of history, constituents, methods of preparation, known or postulated mechanisms underlying responses, the legal basis for use and scientific credibility in the 21st century. Part 1 begins with a consideration of why therapeutic products actually work or appear to do so
To what extent are surgery and invasive procedures effective beyond a placebo response? A systematic review with meta-analysis of randomised, sham controlled trials
Objectives: To assess the quantity and quality of randomised, sham-controlled studies of surgery and invasive procedures and estimate the treatment-specific and non-specific effects of those procedures. Design: Systematic review and meta-analysis. Data sources We searched PubMed, EMBASE, CINAHL, CENTRAL (Cochrane Library), PILOTS, PsycInfo, DoD Biomedical Research, clinicaltrials.gov, NLM catalog and NIH Grantee Publications Database from their inception through January 2015. Study selection We included randomised controlled trials of surgery and invasive procedures that penetrated the skin or an orifice and had a parallel sham procedure for comparison. Data extraction and analysis Three authors independently extracted data and assessed risk of bias. Studies reporting continuous outcomes were pooled and the standardised mean difference (SMD) with 95% CIs was calculated using a random effects model for difference between true and sham groups. Results: 55 studies (3574 patients) were identified meeting inclusion criteria; 39 provided sufficient data for inclusion in the main analysis (2902 patients). The overall SMD of the continuous primary outcome between treatment/sham-control groups was 0.34 (95% CI 0.20 to 0.49; p<0.00001; I2=67%). The SMD for surgery versus sham surgery was non-significant for pain-related conditions (n=15, SMD=0.13, p=0.08), marginally significant for studies on weight loss (n=10, SMD=0.52, p=0.05) and significant for gastroesophageal reflux disorder (GERD) studies (n=5, SMD=0.65, p<0.001) and for other conditions (n=8, SMD=0.44, p=0.004). Mean improvement in sham groups relative to active treatment was larger in pain-related conditions (78%) and obesity (71%) than in GERD (57%) and other conditions (57%), and was smaller in classical-surgery trials (21%) than in endoscopic trials (73%) and those using percutaneous procedures (64%). Conclusions: The non-specific effects of surgery and other invasive procedures are generally large. Particularly in the field of pain-related conditions, more evidence from randomised placebo-controlled trials is needed to avoid continuation of ineffective treatments
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