Resonances in radiative hyperon decays

The importance of resonances for the radiative hyperon decays is examined in the framework of chiral perturbation theory. Low lying baryon resonances are included into the effective theory and tree contributions to these decays are calculated. We find significant contributions to both the parity-conserving and parity-violating decay amplitudes and a large negative value for the asymmetry parameter in polarized Sigma^+ -> p gamma is found, in agreement with the experimental result alpha(p Sigma^+) = -0.76 +/- 0.08.Comment: 14 pages, 2 figure

Baryon Octet magnetic moments in χ\chiPT: More on the importance of the Decuplet

We address the impact of treating the decuplet of spin-3/2 baryons as an explicit degree of freedom in the chiral expansion of the magnetic moments of the octet of spin-1/2 baryons. We carry out a complete calculation of the octet moments to O(1/\lamchic), including decuplet contributions to the chiral loops. In contrast to results of previous analyses, we find that inclusion of the decuplet preserves the convergence behavior of the chiral expansion implied by power counting arguments.Comment: 17 pages, 2 figures. Includes axodraw.sty needed for figures Minor typos correcte

The large-N(c) nuclear potential puzzle

An analysis of the baryon-baryon potential from the point of view of large-N(c) QCD is performed. A comparison is made between the N(c)-scaling behavior directly obtained from an analysis at the quark-gluon level to the N(c)-scaling of the potential for a generic hadronic field theory in which it arises via meson exchanges and for which the parameters of the theory are given by their canonical large-N(c) scaling behavior. The purpose of this comparison is to use large-N(c) consistency to test the widespread view that the interaction between nuclei arises from QCD through the exchange of mesons. Although at the one- and two-meson exchange level the scaling rules for the potential derived from the hadronic theory matches the quark-gluon level prediction, at the three- and higher-meson exchange level a generic hadronic theory yields a potential which scales with N(c) faster than that of the quark-gluon theory.Comment: 17 pages, LaTeX, 5 figure

A Technique for Tensile Fatigue and Creep Testing of Fiber-Reinforced Ceramics

An experimental technique for the elevated temperature tensile fatigue and creep testing of fiber-reinforced ceramics is discussed. The experimental approach utilizes edge-loaded specimens with rectangular gage-sections. Novel furnace and grip designs which allow testing in air to 1500°C are provided. The specimen, furnace and grip designs discussed in the paper have been successfully used to test unidirectional and cross-ply SiCf/Si3N 4, SiCf/SiC, Cf/SiC and SiCf/calcium-aluminosilicate composites.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66679/2/10.1177_002199839202600608.pd

Chiral Lagrangian for Baryons in the 1/Nc1/N_c Expansion

A $1/\N$ expansion of the chiral Lagrangian for baryons is formulated and used to study the low-energy dynamics of baryons interacting with the pion nonet $\pi$, $K$, $\eta$ and $\eta^\prime$ in a combined expansion in chiral symmetry breaking and $1/\N$. Strong $CP$-violation is included. The chiral Lagrangian correctly implements nonet symmetry and contracted spin-flavor symmetry for baryons in the large $\N$ limit. The implications of nonet symmetry for low-energy baryon-pion interactions are described in detail. The procedure for calculating non-analytic pion-loop corrections to baryon amplitudes in the $1/\N$ expansion for finite $\N$ is explained. Flavor-$\bf 27$ baryon mass splittings are calculated at leading order in chiral perturbation theory as an example.Comment: 25 pages, two postscript figure

Modular Equations and Distortion Functions

Modular equations occur in number theory, but it is less known that such equations also occur in the study of deformation properties of quasiconformal mappings. The authors study two important plane quasiconformal distortion functions, obtaining monotonicity and convexity properties, and finding sharp bounds for them. Applications are provided that relate to the quasiconformal Schwarz Lemma and to Schottky's Theorem. These results also yield new bounds for singular values of complete elliptic integrals.Comment: 23 page

Experimentally validated reconstruction and analysis of a genome-scale metabolic model of an anaerobic Neocallimastigomycota fungus

Anaerobic gut fungi in the phylum Neocallimastigomycota typically inhabit the digestive tracts of large mammalian herbivores, where they play an integral role in the decomposition of raw lignocellulose into its constitutive sugar monomers. However, quantitative tools to study their physiology are lacking, partially due to their complex and unresolved metabolism that includes the largely uncharacterized fungal hydrogenosome. Modern omics approaches combined with metabolic modeling can be used to establish an understanding of gut fungal metabolism and develop targeted engineering strategies to harness their degradation capabilities for lignocellulosic bioprocessing. Here, we introduce a high-quality genome of the anaerobic fungus Neocallimastix lanati from which we constructed the first genome-scale metabolic model of an anaerobic fungus. Relative to its size (200 Mbp, sequenced at 62× depth), it is the least fragmented publicly available gut fungal genome to date. Of the 1,788 lignocellulolytic enzymes annotated in the genome, 585 are associated with the fungal cellulosome, underscoring the powerful lignocellulolytic potential of N. lanati. The genome-scale metabolic model captures the primary metabolism of N. lanati and accurately predicts experimentally validated substrate utilization requirements. Additionally, metabolic flux predictions are verified by 13C metabolic flux analysis, demonstrating that the model faithfully describes the underlying fungal metabolism. Furthermore, the model clarifies key aspects of the hydrogenosomal metabolism and can be used as a platform to quantitatively study these biotechnologically important yet poorly understood early-branching fungi

Reorientation-effect measurement of the first 2+ state in 12C : Confirmation of oblate deformation

A Coulomb-excitation reorientation-effect measurement using the TIGRESS γ−ray spectrometer at the TRIUMF/ISAC II facility has permitted the determination of the 〈21 +‖E2ˆ‖21 +〉 diagonal matrix element in 12C from particle−γ coincidence data and state-of-the-art no-core shell model calculations of the nuclear polarizability. The nuclear polarizability for the ground and first-excited (21 +) states in 12C have been calculated using chiral NN N4LO500 and NN+3NF350 interactions, which show convergence and agreement with photo-absorption cross-section data. Predictions show a change in the nuclear polarizability with a substantial increase between the ground state and first excited 21 + state at 4.439 MeV. The polarizability of the 21 + state is introduced into the current and previous Coulomb-excitation reorientation-effect analyses of 12C. Spectroscopic quadrupole moments of QS(21 +)=+0.053(44) eb and QS(21 +)=+0.08(3) eb are determined, respectively, yielding a weighted average of QS(21 +)=+0.071(25) eb, in agreement with recent ab initio calculations. The present measurement confirms that the 21 + state of 12C is oblate and emphasizes the important role played by the nuclear polarizability in Coulomb-excitation studies of light nuclei

A de novo paradigm for male infertility

Genetics of Male Infertility Initiative (GEMINI) consortium: Donald F. Conrad, Liina Nagirnaja, Kenneth I. Aston, Douglas T. Carrell, James M. Hotaling, Timothy G. Jenkins, Rob McLachlan, Moira K. O’Bryan, Peter N. Schlegel, Michael L. Eisenberg, Jay I. Sandlow, Emily S. Jungheim, Kenan R. Omurtag, Alexandra M. Lopes, Susana Seixas, Filipa Carvalho, Susana Fernandes, Alberto Barros, João Gonçalves, Iris Caetano, Graça Pinto, Sónia Correia, Maris Laan, Margus Punab, Ewa Rajpert-De Meyts, Niels Jørgensen, Kristian Almstrup, Csilla G. Krausz & Keith A. Jarvi.De novo mutations are known to play a prominent role in sporadic disorders with reduced fitness. We hypothesize that de novo mutations play an important role in severe male infertility and explain a portion of the genetic causes of this understudied disorder. To test this hypothesis, we utilize trio-based exome sequencing in a cohort of 185 infertile males and their unaffected parents. Following a systematic analysis, 29 of 145 rare (MAF < 0.1%) protein-altering de novo mutations are classified as possibly causative of the male infertility phenotype. We observed a significant enrichment of loss-of-function de novo mutations in loss-of-function-intolerant genes (p-value = 1.00 × 10−5) in infertile men compared to controls. Additionally, we detected a significant increase in predicted pathogenic de novo missense mutations affecting missense-intolerant genes (p-value = 5.01 × 10−4) in contrast to predicted benign de novo mutations. One gene we identify, RBM5, is an essential regulator of male germ cell pre-mRNA splicing and has been previously implicated in male infertility in mice. In a follow-up study, 6 rare pathogenic missense mutations affecting this gene are observed in a cohort of 2,506 infertile patients, whilst we find no such mutations in a cohort of 5,784 fertile men (p-value = 0.03). Our results provide evidence for the role of de novo mutations in severe male infertility and point to new candidate genes affecting fertility.This project was funded by The Netherlands Organization for Scientific Research (918-15-667) to J.A.V. as well as an Investigator Award in Science from the Wellcome Trust (209451) to J.A.V. a grant from the Catherine van Tussenbroek Foundation to M.S.O. a grant from MERCK to R.S. a UUKi Rutherford Fund Fellowship awarded to B.J.H. and the German Research Foundation Clinical Research Unit “Male Germ Cells” (DFG, CRU326) to C.F. and F.T. This project was also supported in part by funding from the Australian National Health and Medical Research Council (APP1120356) to M.K.O.B., by grants from the National Institutes of Health of the United States of America (R01HD078641 to D.F.C. and K.I.A., P50HD096723 to D.F.C.) and from the Biotechnology and Biological Sciences Research Council (BB/S008039/1) to D.J.E.info:eu-repo/semantics/publishedVersio