18 research outputs found
Leukocyte Filtration Improves Pulmonary Function and Reduces the Need for Postoperative Non-Invasive Ventilation
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Cell Proliferation, Apoptosis, and B- and T-Lymphocytes in Peyer's Patches of the Ileum, in Thymus and in Lymph nodes of Preterm Calves, and in Full-Term Calves at Birth and on Day 5 of Life
Peyer's patches, thymus, and lymph nodes contain the majority of lymphocytes. We have studied proliferation rates, apoptosis rates, and numbers of B- and T-lymphocytes in Peyer's patches in ileum, thymus, and mesenterial and prescapular lymph nodes (LM and LP) in unfed preterm calves (GrP; born 13 d before expected normal term after dams were injected with prostaglandin F2α and glucocorticoids) and normal-term calves (GrF) immediately after birth and on d 5 of life after feeding colostrum for 4 d (GrC). Immunohistochemical methods in conjunction with incorporation of 5-bromo-2′-deoxyuridine or terminal deoxynucleotidyl transferase-mediated X-dUTP nick end labeling were used to evaluate cell proliferation rates and apoptosis rates, respectively. The number of T- and B-lymphocytes was determined with monoclonal antibodies directed against CD3 and CD79, respectively. In GrF compared with GrP, there were higher numbers of proliferating and apoptotic cells in LM and LP, of B-lymphocytes in paracortex and follicles of LM and LP, and of proliferating cells in cortex and medulla of thymus. In thymus cortex and medulla, numbers of proliferating cells were higher in GrC than in GrF. Apoptotic rates were generally smaller at all sites of Peyer's patches in GrC than in GrF, and proliferation rates increased from GrP to GrF in intrafollicular areas and from GrF to GrC in all tissues. Numbers of T-lymphocytes in Peyer's patches were higher in GrF than in GrP, but lower in GrC than in GrF, except in the domes. Numbers of B-lymphocytes did not change in Peyer's patches despite high proliferation and low apoptotic rates, suggesting that they leave Peyer's patches during the first days of life. In conclusion, proliferation and apoptosis rates and numbers of B- and T- lymphocytes in Peyer's patches in ileum, thymus, and LM and LP exhibited different developmental changes and were affected by feeding
Preterm as compared with full-term neonatal calves are characterized by morphological and functional immaturity of the small intestine
International audienc
Effects of different colostrum intake on morphology, cell proliferation and enzyme activities in the gut of neonatal calves
International audienc
Intestinal development in neonatal calves: effects of glucocorticoids and dependance on colostrum feeding
International audienc
Effects of Dexamethasone and Growth Hormone Treatment on Hepatic Gluconeogenic Enzymes in Calves
Intestinal Morphology, Epithelial Cell Proliferation, and Absorptive Capacity in Neonatal Calves Fed Milk-Born Insulin-Like Growth Factor-I or a Colostrum Extract
Feeding colostrum, its composition and feeding duration variably modify proliferation and morphology of the intestine and digestive enzyme activities of neonatal calves
International audienc