338 research outputs found
Combined meteorological-hydrological forecasting for the Alipine region with hydrological focus on the Ammer catchment
The MUSE-Wide Survey: A first catalogue of 831 emission line galaxies
We present a first instalment of the MUSE-Wide survey, covering an area of
22.2 arcmin (corresponding to 20% of the final survey) in the
CANDELS/Deep area of the Chandra Deep Field South. We use the MUSE integral
field spectrograph at the ESO VLT to conduct a full-area spectroscopic mapping
at a depth of 1h exposure time per 1 arcmin pointing. We searched for
compact emission line objects using our newly developed LSDCat software based
on a 3-D matched filtering approach, followed by interactive classification and
redshift measurement of the sources. Our catalogue contains 831 distinct
emission line galaxies with redshifts ranging from 0.04 to 6. Roughly one third
(237) of the emission line sources are Lyman emitting galaxies with , only four of which had previously measured spectroscopic redshifts.
At lower redshifts 351 galaxies are detected primarily by their [OII] emission
line (), 189 by their [OIII] line (), and 46 by their H line (). Comparing our spectroscopic redshifts to photometric redshift estimates
from the literature, we find excellent agreement for with a median
of only and an outlier rate of 6%, however a
significant systematic offset of and an outlier rate of 23%
for Ly emitters at . Together with the catalogue we also release
1D PSF-weighted extracted spectra and small 3D datacubes centred on each of the
831 sources.Comment: 24 pages, 14 figures, accepted for publication in A&A, data products
are available for download from http://muse-vlt.eu/science/muse-wide-survey/
and later via the CD
Application of the online coupled meteorology-chemistry model WRF/chem and the Lagrangian model GRAL to the Santiago de Chile region
A case study on the impact of aerosol-radiation feedback on meteorological and regional pollutant distributions
Additivity of the mechanical properties of Al-Sn pseudoalloys
The influence of deformation on the mechanical properties of sintered Al-Sn composites was investigated. It was found that under compression test the strength of investigated materials is an additive value and determined by the rule of mixture. After processing by ECAP the strength of sintered Al-Sn composites increases by more than 2 times but remains additive value. During ECAP, the strengthening of the composites is caused by grinding of the grain structure of the aluminum matrix
The MUSE-Wide Survey: Survey Description and First Data Release
We present the MUSE-Wide survey, a blind, 3D spectroscopic survey in the
CANDELS/GOODS-S and CANDELS/COSMOS regions. Each MUSE-Wide pointing has a depth
of 1 hour and hence targets more extreme and more luminous objects over 10
times the area of the MUSE-Deep fields (Bacon et al. 2017). The legacy value of
MUSE-Wide lies in providing "spectroscopy of everything" without photometric
pre-selection. We describe the data reduction, post-processing and PSF
characterization of the first 44 CANDELS/GOODS-S MUSE-Wide pointings released
with this publication. Using a 3D matched filtering approach we detected 1,602
emission line sources, including 479 Lyman- (Lya) emitting galaxies
with redshifts . We cross-match the emission line
sources to existing photometric catalogs, finding almost complete agreement in
redshifts and stellar masses for our low redshift (z < 1.5) emitters. At high
redshift, we only find ~55% matches to photometric catalogs. We encounter a
higher outlier rate and a systematic offset of z0.2 when
comparing our MUSE redshifts with photometric redshifts. Cross-matching the
emission line sources with X-ray catalogs from the Chandra Deep Field South, we
find 127 matches, including 10 objects with no prior spectroscopic
identification. Stacking X-ray images centered on our Lya emitters yielded no
signal; the Lya population is not dominated by even low luminosity AGN. A total
of 9,205 photometrically selected objects from the CANDELS survey lie in the
MUSE-Wide footprint, which we provide optimally extracted 1D spectra of. We are
able to determine the spectroscopic redshift of 98% of 772 photometrically
selected galaxies brighter than 24th F775W magnitude. All the data in the first
data release - datacubes, catalogs, extracted spectra, maps - are available on
the website https://musewide.aip.de. [abridged]Comment: 25 pages 15+1 figures. Accepted, A&A. Comments welcom
Comparative effectiveness of levetiracetam, valproate and carbamazepine among elderly patients with newly diagnosed epilepsy: subgroup analysis of the randomized, unblinded KOMET study
BACKGROUND: Few clinical trials have evaluated the efficacy and tolerability of antiepileptic drugs (AEDs) as initial monotherapy for elderly patients. METHODS: This post-hoc subgroup analysis of data from an unblinded, randomized, 52-week superiority study (KOMET) compared the effectiveness of levetiracetam (LEV) with extended-release sodium valproate (VPA-ER) and controlled-release carbamazepine (CBZ-CR) as monotherapy in patients aged 60 years with newly diagnosed epilepsy. The physician chose VPA or CBZ as preferred standard treatment; patients were randomized to standard AEDs or LEV. The primary endpoint was time to treatment withdrawal. Results are exploratory, since KOMET was not powered for a subgroup analysis by age.
RESULTS:
Patients (n = 308) were randomized to LEV (n = 48) or VPA-ER (n = 53) in the VPE-ER stratum or to LEV (n = 104) or CBZ-CR (n = 103) in the CBZ-CR stratum. Mean age was 69.6 years, range 60.2-89.9 years (intention-to-treat population n = 307). Time to treatment withdrawal hazard ratio [HR] (95 % confidence interval [CI]) for LEV vs. standard AEDs was 0.44 (0.28-0.67); LEV vs.
VPA-ER: 0.46 (0.16-1.33); LEV vs. CBZ-CR: 0.45 (0.28-0.72). Twelve-month withdrawal rates were: LEV vs. standard AEDs, 20.4 vs. 38.7 %; LEV vs. VPA-ER, 10.4 vs. 23.1 %; LEV vs. CBZ-CR, 25.0 vs. 46.6 %. Time to first seizure was similar between LEV and standard AEDs (HR: 0.92, 95 % CI: 0.63-1.35), LEV and VPA-ER (0.77, 0.38-1.56), and LEV and CBZ-CR (1.02, 0.64-1.63). Adverse events were reported by 76.2, 67.3, and 82.5 % of patients for LEV, VPA-ER, and CBZ-CR, respectively. Discontinuation rates due to AEs were 11.3, 10.2, and 35.0 % for LEV, VPA-ER, and CBZ-CR, respectively.CONCLUSIONS: Time to treatment withdrawal was longer with LEV compared with standard AEDs. This finding was driven primarly by the result in the CBZ-CR stratum, which in turn was likely due to the more favorable tolerability profile of LEV. Results of this post-hoc analysis suggest that LEV(VLID)195291
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