Dusty Sources at the Galactic Center: The N- and Q-band view with VISIR

We present mid-infrared N- and Q-band photometry of the Galactic Center from images obtained with the mid-infrared camera VISIR at the ESO VLT in May 2004. The high resolution and sensitivity possible with VISIR enables us to investigate a total of over 60 point-like sources, an unprecedented number for the Galactic Center at these wavelengths. Combining these data with previous results at shorter wavelengths (Viehmann et al. 2005) enables us to construct SEDs covering the H- to Q-band regions of the spectrum, i.e. 1.6 to 19.5 $\mu$m. We find that the SEDs of certain types of Galactic Center sources show characteristic features. We can clearly distinguish between luminous Northern Arm bow-shock sources, lower luminosity bow-shock sources, hot stars, and cool stars. This characterization may help clarify the status of presently unclassified sources.Comment: 18 pages, 4 figures, 1 table, accepted for publication in the Astrophysical Journa

Orbital analysis of stars in the nuclear stellar disc of the Milky Way

Context. While orbital analysis studies were so far mainly focused on the Galactic halo, it is possible now to do these studies in the heavily obscured region close to the Galactic Centre. Aims. We aim to do a detailed orbital analysis of stars located in the nuclear stellar disc (NSD) of the Milky Way allowing us to trace the dynamical history of this structure. Methods. We integrated orbits of the observed stars in a non-axisymmetric potential. We used a Fourier transform to estimate the orbital frequencies. We compared two orbital classifications, one made by eye and the other with an algorithm, in order to identify the main orbital families. We also compared the Lyapunov and the frequency drift techniques to estimate the chaoticity of the orbits. Results. We identified several orbital families as chaotic, z-tube, x-tube, banana, fish, saucer, pretzel, 5:4, and 5:6 orbits. As expected for stars located in a NSD, the large majority of orbits are identified as z-tubes (or as a sub-family of z-tubes). Since the latter are parented by x2 orbits, this result supports the contribution of the bar (in which x2 orbits are dominant in the inner region) in the formation of the NSD. Moreover, most of the chaotic orbits are found to be contaminants from the bar or bulge which would confirm the predicted contamination from the most recent NSD models. Conclusions. Based on a detailed orbital analysis, we were able to classify orbits into various families, most of which are parented by x2-type orbits, which are dominant in the inner part of the bar

GRAVITY Spectro-interferometric Study of the Massive Multiple Stellar System HD 93206 A

Characterization of the dynamics of massive star systems and the astrophysical properties of the interacting components are a prerequisite for understanding their formation and evolution. Optical interferometry at milliarcsecond resolution is a key observing technique for resolving high-mass multiple compact systems. Here, we report on Very Large Telescope Interferometer/GRAVITY, Magellan/Folded-port InfraRed Echellette, and MPG2.2 m/FEROS observations of the late-O/early-B type system HD 93206 A, which is a member of the massive cluster Collinder 228 in the Carina nebula complex. With a total mass of about $90\,{M}_{\odot }$, it is one of the most compact massive quadruple systems known. In addition to measuring the separation and position angle of the outer binary Aa–Ac, we observe Brγ and He i variability in phase with the orbital motion of the two inner binaries. From the differential phase (${{\rm{\Delta }}}_{\phi }$) analysis, we conclude that the Brγ emission arises from the interaction regions within the components of the individual binaries, which is consistent with previous models for the X-ray emission of the system based on wind–wind interaction. With an average 3σ deviation of ${{\rm{\Delta }}}_{\phi }\sim 15^\circ$, we establish an upper limit of p ~ 0.157 mas (0.35 au) for the size of the Brγ line-emitting region. Future interferometric observations with GRAVITY using the 8 m Unit Telescopes will allow us to constrain the line-emitting regions down to angular sizes of 20 μas (0.05 au at the distance of the Carina nebula)

Constraining scalar fields with stellar kinematics and collisional dark matter

The existence and detection of scalar fields could provide solutions to long-standing puzzles about the nature of dark matter, the dark compact objects at the centre of most galaxies, and other phenomena. Yet, self-interacting scalar fields are very poorly constrained by astronomical observations, leading to great uncertainties in estimates of the mass $m_\phi$ and the self-interacting coupling constant $\lambda$ of these fields. To counter this, we have systematically employed available astronomical observations to develop new constraints, considerably restricting this parameter space. In particular, by exploiting precise observations of stellar dynamics at the centre of our Galaxy and assuming that these dynamics can be explained by a single boson star, we determine an upper limit for the boson star compactness and impose significant limits on the values of the properties of possible scalar fields. Requiring the scalar field particle to follow a collisional dark matter model further narrows these constraints. Most importantly, we find that if a scalar dark matter particle does exist, then it cannot account for both the dark-matter halos and the existence of dark compact objects in galactic nucleiComment: 23 pages, 8 figures; accepted for publication by JCAP after minor change

DYNAMICS OF TIDALLY CAPTURED PLANETS IN THE GALACTIC CENTER

Recent observations suggest ongoing planet formation in the innermost parsec of the Galactic center. The supermassive black hole (SMBH) might strip planets or planetary embryos from their parent star, bringing them close enough to be tidally disrupted. Photoevaporation by the ultraviolet field of young stars, combined with ongoing tidal disruption, could enhance the near-infrared luminosity of such starless planets, making their detection possible even with current facilities. In this paper, we investigate the chance of planet tidal captures by means of high-accuracy N-body simulations exploiting Mikkola's algorithmic regularization. We consider both planets lying in the clockwise (CW) disk and planets initially bound to the S-stars. We show that tidally captured planets remain on orbits close to those of their parent star. Moreover, the semimajor axis of the planetary orbit can be predicted by simple analytic assumptions in the case of prograde orbits. We find that starless planets that were initially bound to CW disk stars have mild eccentricities and tend to remain in the CW disk. However, we speculate that angular momentum diffusion and scattering by other young stars in the CW disk might bring starless planets into orbits with low angular momentum. In contrast, planets initially bound to S-stars are captured by the SMBH on highly eccentric orbits, matching the orbital properties of the clouds G1 and G2. Our predictions apply not only to planets but also to low-mass stars initially bound to the S-stars and tidally captured by the SMBH

Boson-fermion stars: exploring different configurations

We use the flexibility of the concept of a fermion-boson star to explore different configurations, ranging from objects of atomic size and masses of the order $10^{18}$ g, up to objects of galactic masses and gigantic halos around a smaller core, with possible interesting applications to astrophysics and cosmology, particularly in the context of dark matter.Comment: 8 pages. Minor changes, new reference added and a few typos correcte

Архетип свобода у контексті французької політичної теорії та історії

Розглянуто сучасні підходи щодо аналізу політичної ментальності. У межах політологічного аналізу окреслено коло проблем, які потребують вирішення з використанням підходів психології. Зроблено висновок про те, що архетип “свобода” становить важливий елемент політичної ментальності французів.Modern approaches of analysis of political mentality are considered. Within the limits of political science analysis outlined circle of problems which need decision with the use of approaches of psychology. A conclusion is done that archetype freedom makes the important element of political mentality of French’s

Analysis of the FGF gene family provides insights into aquatic adaptation in cetaceans

Cetacean body structure and physiology exhibit dramatic adaptations to their aquatic environment. Fibroblast growth factors (FGFs) are a family of essential factors that regulate animal development and physiology; however, their role in cetacean evolution is not clearly understood. Here, we sequenced the fin whale genome and analysed FGFs from 8 cetaceans. FGF22, a hair follicle-enriched gene, exhibited pseudogenization, indicating that the function of this gene is no longer necessary in cetaceans that have lost most of their body hair. An evolutionary analysis revealed signatures of positive selection for FGF3 and FGF11, genes related to ear and tooth development and hypoxia, respectively. We found a D203G substitution in cetacean FGF9, which was predicted to affect FGF9 homodimerization, suggesting that this gene plays a role in the acquisition of rigid flippers for efficient manoeuvring. Cetaceans utilize low bone density as a buoyancy control mechanism, but the underlying genes are not known. We found that the expression of FGF23, a gene associated with reduced bone density, is greatly increased in the cetacean liver under hypoxic conditions, thus implicating FGF23 in low bone density in cetaceans. Altogether, our results provide novel insights into the roles of FGFs in cetacean adaptation to the aquatic environment.ope

DNA Immunization with Fusion of CTLA-4 to Hepatitis B Virus (HBV) Core Protein Enhanced Th2 Type Responses and Cleared HBV with an Accelerated Kinetic

BACKGROUND: Typically, DNA immunization via the intramuscular route induces specific, Th1-dominant immune responses. However, plasmids expressing viral proteins fused to cytotoxic T lymphocyte antigen 4 (CTLA-4) primed Th2-biased responses and were able to induced effective protection against viral challenge in the woodchuck model. Thus, we addressed the question in the mouse model how the Th1/Th2 bias of primed immune responses by a DNA vaccine influences hepatitis B virus (HBV) clearance. PRINCIPAL FINDINGS: Plasmids expressing HBV core protein (HBcAg) or HBV e antigen and HBcAg fused to the extracellular domain of CTLA-4 (pCTLA-4-HBc), CD27, and full length CD40L were constructed. Immunizations of these DNA plasmids induced HBcAg-specific antibody and cytotoxic T-cell responses in mice, but with different characteristics regarding the titers and subtypes of specific antibodies and intensity of T-cell responses. The plasmid pHBc expressing HBcAg induced an IgG2a-dominant response while immunizations of pCTLA-4-HBc induced a balanced IgG1/IgG2a response. To assess the protective values of the immune responses of different characteristics, mice were pre-immunized with pCTLA-4-HBc and pHBc, and challenged by hydrodynamic injection (HI) of pAAV/HBV1.2. HBV surface antigen (HBsAg) and DNA in peripheral blood and HBcAg in liver tissue were cleared with significantly accelerated kinetics in both groups. The clearance of HBsAg was completed within 16 days in immunized mice while more than 50% of the control mice are still positive for HBsAg on day 22. Stronger HBcAg-specific T-cell responses were primed by pHBc correlating with a more rapid decline of HBcAg expression in liver tissue, while anti-HBs antibody response developed rapidly in the mice immunized with pCTLA-4-HBc, indicating that the Th1/Th2 bias of vaccine-primed immune responses influences the mode of viral clearance. CONCLUSION: Viral clearance could be efficiently achieved by Th1/Th2-balanced immune response, with a small but significant shift in T-cell and B-cell immune responses

Status of research and development of vaccines for Streptococcus pyogenes.

Streptococcus pyogenes is an important global pathogen, causing considerable morbidity and mortality, especially in low and middle income countries where rheumatic heart disease and invasive infections are common. There is a number of promising vaccine candidates, most notably those based on the M protein, the key virulence factor for the bacterium. Vaccines against Streptococcus pyogenes are considered as impeded vaccines because of a number of crucial barriers to development. Considerable effort is needed by key players to bring current vaccine candidates through phase III clinical trials and there is a clear need to develop a roadmap for future development of current and new candidates