644 research outputs found

    Системы измерения параметров волнения для подводных аппаратов

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    Выпускная квалификационная работа 97 с., 18 рис., 21 табл., 21 источник, 4 прил. Цель работы – проверка теоретической возможности регистрации и обработки данных о величине морского волнения на некоторой глубине, создание макета прибора, измеряющего соответствующее волнение, на основе датчика акселерометра. Область применения: система управления для автономного необитаемого подводного аппарата. В процессе исследования проводились: теоретический обзор линеаризованной теории волны, испытания пригодности акселерометра для задачи измерения вертикальной составляющей при волновом движении, проектирование макета, написание программы для микроконтроллера, изготовление печатной платы макета.Final qualifying work 97 p., 18 fig., 21 tab., 21 sources, 4 app. The Purpose is to test the theoretical possibility of registration and processing of data on the magnitude of sea waves at a certain depth, the creation of the layout of the device, which measures the corresponding sea swell, based on the accelerometer sensor. Scope: control system for autonomous underwater vehicle. A theoretical overview of the linearized theory of wave test accelerometer suitability for vertical component measurement tasks with wave motion, layout design, writing programs for the microcontroller and making the printed board layout were carried out while research

    Обеспечение безопасности радиоактивных источников на гипотетическом объекте

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    Объектом исследования является вопросы организации и функционирования систем физической защиты, учета и контроля ядерных материалов. Целью работы является создание методического подхода для описания и построения гипотетического объекта и его систем безопасности, с дальнейшем его применением в учебных целях по специальности Безопасность и нераспространение ядерных материалов.The object of research is the organization and functioning of systems of physical protection, accounting and control of nuclear materials. The aim of the work is to create a methodological approach to the description and construction of a hypothetical object and its security systems, with its further application for educational purposes in the specialty safety and non-proliferation of nuclear materials

    Влияние интенсивной пластической деформации методом кручения под квазигидростатическим давлением на структуру и фазовый состав высокоазотистой аустенитной стали Х20АГ20Ф2

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    We investigate the microstructure and microhardness of high-nitrogen austenitic steel Fe-20Cr-20Mn-2.6V-0.3C-0.8N (in wt. %) after upset and high-pressure torsion (HPT) (6GPa) for ?, ?, and 1 revolutions at room temperature. As the result of deformation, steel microhardness increases by 1.5 times after HPT. Slip, twinning, formation of localized deformation microbands, and precipitation hardening are the main deformation mechanisms under HPT, and the level of solid solution strengthening of steel remains high after deformation

    Photothermal treatment of cutaneous lesions

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    This thesis reviews the understanding of the processes involved in the laser treatment of cutaneous blemishes. The current treatment protocol for the treatment of vascular lesions - double scanning with transient blanching used at St George's Hospital is shown to give excellent results. The protocol takes advantage of the precise control provided by the SCANALL automatic scanner and the 5 W, 578 nm output of the copper vapour laser. The clinical endpoint - transient blanching - is shown to be due to a temporary halting of blood flow (probably by vasoconstriction) rather than coagulation necrosis of overlying tissues. Various models of the laser treatment of vascular lesions are presented and examined. A histological study of the double scanning, transient blanching protocol shows that tissue damage is confined to vascular and perivascular tissue. Cosmetic lightening is due to a reduction in both the number and size of the vessels in the upper dermis. The protocol is also investigated by interview and postal survey. The incidence of adverse effects is small. For example, there are only two 1 cm² adverse skin texture changes in 64000cm² of treated area. Patients receiving treatment for telangiectasia and spider naevus are satisfied with the outcome after one or two treatments, but many with port-wine stain cease treatment after four sessions when government funding runs out. Patient perception of the success is compared with the surgeon's perception. Patients often needed to be reminded of the size and severity of their original lesion with a photograph. The thesis reports on a parallel investigation of the use of millisecond scale pulses of white light for the treatment of tattoos. A xenon flash-lamp system is designed, constructed, and used in a clinical trial. This includes building pulse forming networks to produce rectangular current pulses of differing lengths. During the clinical trial the system produced a strong inflammatory response in the skin adjacent to the pigment, and lightening of the tattoo. Modelling, histology and other literature studies lead to the conclusion that the pulse length is too long to cause the explosive rupture of pigment-containing cells observed after Q-switched laser treatment, and too short to cause sufficient necrosis and phagocytosis of the pigment-containing cells for it to be useful clinically. The thesis also describes the construction of a device to measure muscle tension during tendon transfer surgery. The device uses diffraction to measure the separation of the fundamental unit of muscle tissue - the sarcomere

    Разработка модуля сбора и преобразования вибрации для питания беспроводных устройств на техногенных объектах

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    Конструирование модуля сбора и преобразования энергии вибрации для питания беспроводных датчиков технического диагностирования на техногенных объектахConstruction of a module for the collection and conversion of vibration energy for the supply of wireless sensors for technical diagnostics on industrial object

    Low angular momentum flow model of Sgr A* activity

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    Sgr A* is the closest massive black hole and can be observed with the highest angular resolution. Nevertheless, our current understanding of the accretion process in this source is very poor. The inflow is almost certainly of low radiative efficiency and it is accompanied by a strong outflow and the flow is strongly variable but the details of the dynamics are unknown. Even the amount of angular momentum in the flow is an open question. Here we argue that low angular momentum scenario is better suited to explain the flow variability. We present a new hybrid model which describes such a flow and consists of an outer spherically symmetric Bondi flow and an inner axially symmetric flow described through MHD simulations. The assumed angular momentum of the matter is low, i.e. the corresponding circularization radius in the equatorial plane of the flow is just above the innermost stable circular orbit in pseudo-Newtonian potential. We compare the radiation spectrum from such a flow to the broad band observational data for Sgr A*.Comment: Proceedings of the AHAR 2008 Conference: The Universe under the Microscope; Astrophysics at High Angular Resolution, Bad Honef

    A Bioluminescent Sensor for Rapid Detection of PPEP-1, a Clostridioides difficile Biomarker

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    Current assays for Clostridioides difficile in nonhospital settings are outsourced and time-intensive, resulting in both delayed diagnosis and quarantining of infected individuals. We designed a more rapid point-of-care assay featuring a "turn-on " bioluminescent readout of a C. difficile-specific protease, PPEP-1. NanoLuc, a bright and stable luciferase, was "caged " with a PPEP-1-responsive peptide tail that inhibited luminescence. Upon proteolytic cleavage, the peptide was released and NanoLuc activity was restored, providing a visible readout. The bioluminescent sensor detected PPEP-1 concentrations as low as 10 nM. Sensor uncaging was achieved within minutes, and signal was captured using a digital camera. Importantly, the sensor was also functional at ambient temperature and compatible with fecal material, suggesting that it can be readily deployed in a variety of settings.Proteomic
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