Listening to galaxies tuning at z ~ 2.5 - 3.0: The first strikes of the Hubble fork

We investigate the morphological properties of 494 galaxies selected from the GMASS survey at z>1, primarily in their optical rest frame, using HST images, from the CANDELS survey. We propose that the Hubble sequence of galaxy morphologies takes shape at redshift 2.5<z<3. The fractions of both ellipticals and disks decrease with increasing lookback time at z>1, such that at redshifts z=2.5-2.7 and above, the Hubble types cannot be identified, and most galaxies are classified as irregular. The quantitative morphological analysis shows that, at 1<z<3, morphological parameters are not as effective in distinguishing the different morphological Hubble types as they are at low redshift. No significant morphological k-correction was found to be required for the Hubble type classification, with some exceptions. In general, different morphological types occupy the two peaks of the rest-frame (U-B) colour bimodality of galaxies: most irregulars occupy the blue peak, while ellipticals are mainly found in the red peak, though with some level of contamination. Disks are more evenly distributed than either irregulars and ellipticals. We find that the position of a galaxy in a UVJ diagram is related to its morphological type: the "quiescent" region of the plot is mainly occupied by ellipticals and, to a lesser extent, by disks. We find that only ~33% of all morphological ellipticals in our sample are red and passively evolving galaxies. Blue galaxies morphologically classified as ellipticals show a remarkable structural similarity to red ones. Almost all irregulars have a star-forming galaxy spectrum. In addition, the majority of disks show some sign of star-formation activity in their spectra, though in some cases their red continuum is indicative of old stellar populations. Finally, an elliptical morphology may be associated with either passively evolving or strongly star-forming galaxies.Comment: 27 pages, 16 figures, 5 tables. "Morphological atlas" in the appendix. Revised version accepted for publication in A&

Abnormal connectivity between the default mode and the visual system underlies the manifestation of visual hallucinations in Parkinson’s disease:A task-based fMRI study

Background: The neural substrates of visual hallucinations remain an enigma, due primarily to the difficulties associated with directly interrogating the brain during hallucinatory episodes. Aims: To delineate the functional patterns of brain network activity and connectivity underlying visual hallucinations in Parkinson’s disease. Methods: In this study, we combined functional magnetic resonance imaging (MRI) with a behavioral task capable of eliciting visual misperceptions, a confirmed surrogate for visual hallucinations, in 35 patients with idiopathic Parkinson’s disease. We then applied an independent component analysis to extract time series information for large-scale neuronal networks that have been previously implicated in the pathophysiology of visual hallucinations. These data were subjected to a task-based functional connectivity analysis, thus providing the first objective description of the neural activity and connectivity during visual hallucinations in patients with Parkinson’s disease. Results: Correct performance of the task was associated with increased activity in primary visual regions; however, during visual misperceptions, this same visual network became actively coupled with the default mode network (DMN). Further, the frequency of misperception errors on the task was positively correlated with the strength of connectivity between these two systems, as well as with decreased activity in the dorsal attention network (DAN), and with impaired connectivity between the DAN and the DMNs, and ventral attention networks. Finally, each of the network abnormalities identified in our analysis were significantly correlated with two independent clinical measures of hallucination severity. Conclusions: Together, these results provide evidence that visual hallucinations are due to increased engagement of the DMN with the primary visual system, and emphasize the role of dysfunctional engagement of attentional networks in the pathophysiology of hallucinations

Immune responses of mice to iodoacetate-treated Ehrlich ascites tumour cells.

1. Mice of two different strains (CBA and Herston white) failed to develop marked resistance to Ehrlich ascites tumour when immunized with iodoacetatetreated tumour cells, a procedure reported by others to be effective in protecting A-jax mice. 2. No circulating anti-tumour antibodies could be detected in the sera of the immunized mice, by a variety of techniques. 3. Delayed-type hypersensitivity to disrupted tumour cells was present in the immunized mice to a highly significant degree; however, this was not correlated with resistance to challenge with live tumour. 4. The possible reasons for the above observations are discussed

Gold-alkynyls in catalysis : Alkyne activation, gold cumulenes and nuclearity

The use of cationic gold(i) species in the activation of substrates containing CC bonds has become a valuable tool for synthetic chemists. Despite the seemingly simple label of 'alkyne activation', numerous patterns of reactivity and product structure are observed in systems employing related substrates and catalysts. The complications of mechanistic determination are compounded as the number of implicated gold(i) centres involved in catalysis increases and debate about the bonding in proposed intermediates clouds the number and importance of potential reaction pathways. This perspective aims to illustrate some of the principles underpinning gold-alkynyl interactions whilst highlighting some of the contentious areas in the field and offering some insight into other, often ignored, mechanistic possibilities based on recent findings

AGN feedback at z~2 and the mutual evolution of active and inactive galaxies

The relationships between galaxies of intermediate stellar mass and moderate luminosity active galactic nuclei (AGNs) at 1<z<3 are investigated with the Galaxy Mass Assembly ultra-deep Spectroscopic Survey (GMASS) sample complemented with public data in the GOODS-South field. Using X-ray data, hidden AGNs are identified in unsuspected star-forming galaxies with no apparent signs of non-stellar activity. In the color-mass plane, two parallel trends emerge during the ~2 Gyr between the average redshifts z~2.2 and z~1.3: while the red sequence becomes significantly more populated by ellipticals, the majority of AGNs with L(2-10 keV)>10^42.3 erg s^-1 disappear from the blue cloud/green valley where they were hosted predominantly by star-forming systems with disk and irregular morphologies. These results are even clearer when the rest-frame colors are corrected for dust reddening. At z~2.2, the ultraviolet spectra of active galaxies (including two Type 1 AGNs) show possible gas outflows with velocities up to about -500 km s^-1 that are not observed neither in inactive systems at the same redshift, nor at lower redshifts. Such outflows indicate the presence of gas that can move faster than the escape velocities of active galaxies. These results suggest that feedback from moderately luminous AGNs (logL_X~2 by contributing to outflows capable of ejecting part of the interstellar medium and leading to a rapid decrease in the star formation in host galaxies with stellar masses 10<logM<11 M_Sun.Comment: Astrophysical Journal Letters, in press (6 pages, 4 figures

On the use of low-cost computer peripherals for the assessment of motor dysfunction in Parkinson’s disease – Quantification of bradykinesia using target tracking tasks

The potential of computer games peripherals to measure the motor dysfunction in Parkinson’s diseases is assessed. Of particular interest is the quantification of bradykinesia. Previous studies used modified or custom haptic interfaces, here an unmodified force feedback joystick and steering wheel are used with a laptop. During testing an on screen cursor moves in response to movements of the peripheral, the user has to track a continuously moving target (pursuit tracking), or move to a predetermined target (step tracking). All tasks use movement in the horizontal axis, allowing use of joystick or steering wheel. Two pursuit tracking tasks are evaluated, pseudo random movement, and a swept frequency task. Two step tracking tasks are evaluated, movement between two or between two of five fixed targets. Thirteen patients and five controls took part on a weekly basis. Patients were assessed for bradykinesia at each session using standard clinical measures. A range of quantitative measures was developed to allow comparison between and within patients and controls using ANOVA. Both peripherals are capable of discriminating between controls and patients, and between patients with different levels of bradykinesia. Recommendations for test procedures and peripherals are given

Online leadership discourse in higher education: a digital multimodal discourse perspective

As leadership discourses in higher education are increasingly being mediated online, texts previously reserved for staff are now being made available in the public domain. As such, these texts become accessible for study, critique and evaluation. Additionally, discourses previously confined to the written domain are now increasingly multimodal. Thus, an approach is required that is capable of relating detailed, complex multimodal discourse analyses to broader sociocultural perspectives to account for the complex meaning-making practices that operate in online leadership discourses. For this purpose, a digital multimodal discourse approach is proposed and illustrated via a small-scale case study of the online leadership discourse of an Australian university. The analysis of two short video texts demonstrates how a digital multimodal discourse perspective facilitates the identification of key multimodal systems used for meaning-making in online communication, how meaning arises through combinations of semiotic choices (not individual choices), and how the results of multimodal discourse analysis using digital technology can reveal larger sociocultural patterns – in this case, divergent leadership styles and approaches as reflected in online discourse, at a time of immense change within the higher education sector

Long-Range Excitons in Optical Absorption Spectra of Electroluminescent Polymer Poly(para-phenylenevinylene)

The component of photoexcited states with large spatial extent is investigated for poly(para-phenylenevinylene) using the intermediate exciton theory. We find a peak due to long-range excitons at the higher-energy side of the lowest main feature of optical spectra. The fact that the onset of long-range excitons is located near the energy gap is related to the mechanisms of large photocurrents measured in such energy regions. We show that a large value of the hopping integral is realistic for characterizing optical excitations.Comment: To be published in J. Phys. Soc. Jpn. (Letters

Role of inertia in two-dimensional deformation and breakup of a droplet

We investigate by Lattice Boltzmann methods the effect of inertia on the deformation and break-up of a two-dimensional fluid droplet surrounded by fluid of equal viscosity (in a confined geometry) whose shear rate is increased very slowly. We give evidence that in two dimensions inertia is {\em necessary} for break-up, so that at zero Reynolds number the droplet deforms indefinitely without breaking. We identify two different routes to breakup via two-lobed and three-lobed structures respectively, and give evidence for a sharp transition between these routes as parameters are varied.Comment: 4 pages, 4 figure

A Study of the N=2N=2 Kazakov-Migdal Model

We study numerically the SU(2) Kazakov-Migdal model of `induced QCD'. In contrast to our earlier work on the subject we have chosen here {\it not} to integrate out the gauge fields but to keep them in the Monte Carlo simulation. This allows us to measure observables associated with the gauge fields and thereby address the problem of the local $Z_2$ symmetry present in the model. We confirm our previous result that the model has a line of first order phase transitions terminating in a critical point. The adjoint plaquette has a clear discontinuity across the phase transition, whereas the plaquette in the fundamental representation is always zero in accordance with Elitzur's theorem. The density of small $Z_2$ monopoles shows very little variation and is always large. We also find that the model has extra local U(1) symmetries which do not exist in the case of the standard adjoint theory. As a result, we are able to show that two of the angles parameterizing the gauge field completely decouple from the theory and the continuum limit defined around the critical point can therefore not be `QCD'.Comment: 11 pages, UTHEP-24