313 research outputs found
El Rol de la Cooperación Internacional y los Programas de Lucha contra la Pobreza en el Perú
La presente tesis “El rol de la Cooperación Internacional y los Programas de Lucha contra la Pobreza en el Perú”, tiene su origen en el año 2000, cuando se cursaron las asignaturas Seminario de Tesis I Seminario de Tesis II, correspondientes al 9º y 10º semestres académicos de la carrera de Economía. Por ese entonces, era evidente que los recursos prevenientes de la cooperación internacional eran importantes como mecanismo de financiamiento –complementarios a los fondos del sector público y para la sociedad civil (ONG)- en la lucha para reducir la pobreza en el país, desembolsos que eran manifiestamente crecientes desde el inicio de la década de los años ’90.
Este trabajo de investigación no se ha librado de ciertas dificultades para su elaboración, lo cual se explica por la propia naturaleza del trabajo. En el país existen casi 2000 entidades operando que reciben recursos de la cooperación internacional para aproximadamente 4000 proyectos (existen un total de 5000 proyectos). El consolidar y la agregación constituyen un serio problema, debido a que muchos proyectos se encuentran ubicados (atomizados) en una misma localidad, y a su vez otros proyectos operan en múltiples localidades es decir, existe una gran dispersión, dada su realización en todo el territorio del país. Estos aspectos, más allá de la consolidación y agregación, generan otros problemas, como es la medición física o real del impacto de los proyectos financiados con recursos de la cooperación internacional en la reducción de la pobreza en el país. He aquí la razón del por qué la APCI solo cuenta con datos de índole monetario sobre los recursos provenientes de la cooperación internacional a nivel de proyectos (tarea titánica ciertamente y su consolidación correspondiente. La tesis que se presenta contiene cinco capítulos, el primero referido a la presencia de la cooperación internacional en el país. El segundo capítulo, analiza el efecto de ser considerado el Perú en el presente como un país de renta media alta y las limitaciones el ingreso per cápita como indicador determinante para los donantes para efectuar las transferencias de recursos. El tercer capitulo trata el tema de cómo se han venido distribuyendo los recursos de la cooperación internacional en el Perú siendo principalmente el problema de la concentración de fondos en la capital. Los capítulos, cuarto y quinto están referidos al desarrollo futuro de la cooperación internacional en el Perú y su relación con la disminución de la pobreza.
Debo expresar mi reconocimiento y agradecimiento a los funcionarios de la APCI por su valioso apoyo en el esclarecimiento del tema materia de investigación y la información proporcionada; así como a mi asesor, el Econ. Luis Delgadillo, por su perseverancia e indispensable apoyo con sus consejos y recomendaciones sumamente pertinentes. De hecho, las limitaciones de esta investigación son de mi entera responsabilidad y como tal se asumen.Tesi
Representation of tropical deep convection in atmospheric models - Part 1 : Meteorology and comparison with satellite observations
Published under Creative Commons Licence 3.0. Original article can be found at : http://www.atmospheric-chemistry-and-physics.net/ "The author's copyright for this publication is transferred to University of Hertfordshire".Fast convective transport in the tropics can efficiently redistribute water vapour and pollutants up to the upper troposphere. In this study we compare tropical convection characteristics for the year 2005 in a range of atmospheric models, including numerical weather prediction (NWP) models, chemistry transport models (CTMs), and chemistry-climate models (CCMs). The model runs have been performed within the framework of the SCOUT-O3 (Stratospheric-Climate Links with Emphasis on the Upper Troposphere and Lower Stratosphere) project. The characteristics of tropical convection, such as seasonal cycle, land/sea contrast and vertical extent, are analysed using satellite observations as a benchmark for model simulations. The observational datasets used in this work comprise precipitation rates, outgoing longwave radiation, cloud-top pressure, and water vapour from a number of independent sources, including ERA-Interim analyses. Most models are generally able to reproduce the seasonal cycle and strength of precipitation for continental regions but show larger discrepancies with observations for the Maritime Continent region. The frequency distribution of high clouds from models and observations is calculated using highly temporally-resolved (up to 3-hourly) cloud top data. The percentage of clouds above 15 km varies significantly between the models. Vertical profiles of water vapour in the upper troposphere-lower stratosphere (UTLS) show large differences between the models which can only be partly attributed to temperature differences. If a convective plume reaches above the level of zero net radiative heating, which is estimated to be ~15 km in the tropics, the air detrained from it can be transported upwards by radiative heating into the lower stratosphere. In this context, we discuss the role of tropical convection as a precursor for the transport of short-lived species into the lower stratosphere.Peer reviewe
Costos de la otitis media aguda en niños de una ciudad de la costa caribe colombiana
Acute otitis media is the main cause of consultation, antibiotic use, and
ambulatory surgery in developed countries; besides, it is associated with an important
economic burden. However, non-medical indirect costs of acute otitis media, which are
relevant in this pathology, have been underestimatedLa otitis media aguda es la principal causa de consultas médicas, de uso
de antibióticos y de cirugías ambulatorias en los países desarrollados. Está asociada con
una significativa carga económica, pero sus costos indirectos no médicos, los cuales son
relevantes en esta enfermedad, se han subestimad
How realistic are air quality hindcasts driven by forcings from climate model simulations?
Predicting how European air quality could evolve over the next decades in the context of changing climate requires the use of climate models to produce results that can be averaged in a climatologically and statistically sound manner. This is a very different approach from the one that is generally used for air quality hindcasts for the present period; analysed meteorological fields are used to represent specifically each date and hour. Differences arise both from the fact that a climate model run results in a pure model output, with no influence from observations (which are useful to correct for a range of errors), and that in a "climate" set-up, simulations on a given day, month or even season cannot be related to any specific period of time (but can just be interpreted in a climatological sense). Hence, although an air quality model can be thoroughly validated in a "realistic" set-up using analysed meteorological fields, the question remains of how far its outputs can be interpreted in a "climate" set-up. For this purpose, we focus on Europe and on the current decade using three 5-yr simulations performed with the multiscale chemistry-transport model MOCAGE and use meteorological forcings either from operational meteorological analyses or from climate simulations. We investigate how statistical skill indicators compare in the different simulations, discriminating also the effects of meteorology on atmospheric fields (winds, temperature, humidity, pressure, etc.) and on the dependent emissions and deposition processes (volatile organic compound emissions, deposition velocities, etc.). Our results show in particular how differing boundary layer heights and deposition velocities affect horizontal and vertical distributions of species. When the model is driven by operational analyses, the simulation accurately reproduces the observed values of O<sub>3</sub>, NO<sub>x</sub>, SO<sub>2</sub> and, with some bias that can be explained by the set-up, PM<sub>10</sub>. We study how the simulations driven by climate forcings differ, both due to the realism of the forcings (lack of data assimilated and lower resolution) and due to the lack of representation of the actual chronology of events. We conclude that the indicators such as mean bias, mean normalized bias, RMSE and deviation standards can be used to interpret the results with some confidence as well as the health-related indicators such as the number of days of exceedance of regulatory thresholds. These metrics are thus considered to be suitable for the interpretation of simulations of the future evolution of European air quality
Three-dimensional growth as multicellular spheroid activates the proangiogenic phenotype of colorectal carcinoma cells via LFA-1-dependent VEGF: implications on hepatic micrometastasis
Background: The recruitment of vascular stromal and endothelial cells is an early event occurring during cancer cell growth at premetastatic niches, but how the microenvironment created by the initial three-dimensional (3D) growth of cancer cells affects their angiogenesis-stimulating potential is unclear.
Methods: The proangiogenic profile of CT26 murine colorectal carcinoma cells was studied in seven-day cultured 3D-spheroids of <300 mu m in diameter, produced by the hanging-drop method to mimic the microenvironment of avascular micrometastases prior to hypoxia occurrence.
Results: Spheroid-derived CT26 cells increased vascular endothelial growth factor (VEGF) secretion by 70%, which in turn increased the in vitro migration of primary cultured hepatic sinusoidal endothelium (HSE) cells by 2-fold. More importantly, spheroid-derived CT26 cells increased lymphocyte function associated antigen (LFA)-1-expressing cell fraction by 3-fold; and soluble intercellular adhesion molecule (ICAM)-1, given to spheroid-cultured CT26 cells, further increased VEGF secretion by 90%, via cyclooxygenase (COX)-2-dependent mechanism. Consistent with these findings, CT26 cancer cells significantly increased LFA-1 expression in non-hypoxic avascular micrometastases at their earliest inception within hepatic lobules in vivo; and angiogenesis also markedly increased in both subcutaneous tumors and hepatic metastases produced by spheroid-derived CT26 cells.
Conclusion: 3D-growth per se enriched the proangiogenic phenotype of cancer cells growing as multicellular spheroids or as subclinical hepatic micrometastases. The contribution of integrin LFA-1 to VEGF secretion via COX-2 was a micro environmental-related mechanism leading to the pro-angiogenic activation of soluble ICAM-1-activated colorectal carcinoma cells. This mechanism may represent a new target for specific therapeutic strategies designed to block colorectal cancer cell growth at a subclinical micrometastatic stage within the liver.Supported in part by Pharmakine S. L., and by grants from the CICYT of the Spanish government (SAF2006-09341), and the Basque Country Government (IT-487-07
Subitizing with Variational Autoencoders
Numerosity, the number of objects in a set, is a basic property of a given
visual scene. Many animals develop the perceptual ability to subitize: the
near-instantaneous identification of the numerosity in small sets of visual
items. In computer vision, it has been shown that numerosity emerges as a
statistical property in neural networks during unsupervised learning from
simple synthetic images. In this work, we focus on more complex natural images
using unsupervised hierarchical neural networks. Specifically, we show that
variational autoencoders are able to spontaneously perform subitizing after
training without supervision on a large amount images from the Salient Object
Subitizing dataset. While our method is unable to outperform supervised
convolutional networks for subitizing, we observe that the networks learn to
encode numerosity as basic visual property. Moreover, we find that the learned
representations are likely invariant to object area; an observation in
alignment with studies on biological neural networks in cognitive neuroscience
Concepto fotosíntesis en profesores desde el análisis de sus modelos mentales
El presente estudio es una aproximación a los modelos mentales sobre el concepto fotosíntesis en cuatro profesores que enseñan ciencias naturales, en 5º y 11° de Educación Básica y Media respectivamente, de escuelas estatales de Barranquilla, Colombia. Se desarrolló como diseño metodológico un estudio de casos múltiples. Los resultados se analizan desde una metodología de corte cualitativo, describiendo dos aspectos del modelo del profesor: el constituyente ontológico y el epistemológico, mediante la aplicación del modelo ONEPSI (Gutiérrez 2001). El modelo mental explicativo del profesor, se contrasta con el Modelo Científico del concepto fotosíntesis y finalmente se muestran sus alcances y limitaciones, al tiempo que se presenta una reflexión crítica respecto a la enseñanza de este concepto crucial frente a los retos ambientales de nuestro planeta
SpikeletFCN: Counting Spikelets from Infield Wheat Crop Images Using Fully Convolutional Networks
Currently, crop management through automatic monitoring is growing momentum, but presents various challenges. One key challenge is to quantify yield traits from images captured automatically. Wheat is one of the three major crops in the world with a total demand expected to exceed 850 million tons by 2050. In this paper we attempt estimation of wheat spikelets from high-definition RGB infield images using a fully convolutional model. We propose also the use of transfer learning and segmentation to improve the model. We report cross validated Mean Absolute Error (MAE) and Mean Square Error (MSE) of 53.0, 71.2 respectively on 15 real field images. We produce visualisations which show the good fit of our model to the task. We also concluded that both transfer learning and segmentation lead to a very positive impact for CNN-based models, reducing error by up to 89%, when extracting key traits such as wheat spikelet counts
A Comprehensive Pediatric Asthma Management Program Reduces Emergency Department Visits and Hospitalizations
We evaluated the impact of a comprehensive pediatric asthma management program (the Children's Asthma Wellness Program, CAWP) on the frequency of emergency department (ED) visits and hospital admissions. The CAWP generally consisted of 4 clinic sessions over a 1-year period, but some patients attended fewer clinic sessions, and some required additional clinic sessions due to incomplete asthma control. Patients were evaluated and treated by pediatric pulmonologists, nurse asthma care coordinator/educator, and social worker. We retrospectively reviewed program results over an 8-year period (2005?2013). We compared ED visits and hospital admissions before and after participation in the CAWP. There were 254 children referred to the CAWP; 172 children were enrolled. Fifty-four children (31%) received >6 sessions due to incomplete asthma control. On average, children requiring additional clinic sessions were older and more likely to be African American, hold Medicaid insurance, and have severe asthma. We obtained a minimum of 1-year preprogram and 1-year postprogram administrative data for 86 children (50%). Using each participating child as his/her own control, we found that taking part in the program decreased the risk of ED visits to 0.26 times the preprogram rate (P?Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/140178/1/ped.2015.0561.pd
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