483 research outputs found

    The Impact of Course Title and Instructor Gender on Student Perceptions and Interest in a Women's and Gender Studies Course

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    Diversity awareness has enormous benefits, and universities in the United States increasingly require students to complete diversity-related courses. Prior research has demonstrated that students' initial attitudes toward these courses affect their subsequent engagement, as well as the quality of their learning experience; however, very little research has examined how these initial attitudes are formed. We conducted an experiment to examine this issue in the context of a women's and gender studies course in psychology. Participants read one of two identical course descriptions that varied only the course title (i.e., Psychology of Gender versus Psychology of Women) and instructor gender. Participants perceived a women-titled course to be narrowly focused compared to an identical gender-titled course and were more interested in taking the gender-titled course. Instructor gender had no effects on any of the variables. Additionally, female participants had more positive attitudes toward the course than male participants, regardless of title. Exploratory mediation analyses indicated that the main effects of course title and participant gender were mediated by perceptions of course content. Implications for improving student experiences and interest in diversity-related courses are discussed

    ON THE EXPRESSIVE POWER OF THE RELATIONAL MODEL: A DATABASE DESIGNER\u27S POINT OF VIEW

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    The purpose of this paper is to introduce a framework for assessing the expressive power of data models and to apply this framework to the relational model of data. From a designer\u27s point of view, a data model such as the relational model should not only be formally defined and easy to understand, but should also provide a powerful set of constructs to model real-world phenomena. The expressive power of a data model, defined as the degree to which its constructs match with constructs encountered in reality, can be judged by two complementary principles: the interpretation principle and the representation principle. It is asserted that database designers attempt to minimize the number of ad hoc database constraints, and that a data model faithful to the two principles supports this design strategy. Subsequently, this constraint minimization strategy is used to assess the expressive power of a particular data model, i.e., the relational data model. The authors take the position that the expressive power of the relational model is not optimal, due to a lack of adherence to both the interpretation principle and the representation principle. The paper amplifies this position by means of a number of examples, all based on publications by Codd and Date

    Long-term observations of the background aerosol at Cabauw, The Netherlands

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    Long-term measurements of PM2.5 mass concentrations and aerosol particle size distributions from 2008 to 2015, as well as hygroscopicity measurements conducted over one year (2008-2009) at Cabauw, The Netherlands, are compiled here in order to provide a comprehensive dataset for understanding the trends and annual variabilities of the atmospheric aerosol in the region. PM2.5 concentrations have a mean value of 14.4 mu g m(-3) with standard deviation 2.1 mu g m(-3), and exhibit an overall decreasing trend of -0.74 mu g m(-3) year(-1). The highest values are observed in winter and spring and are associated with a shallower boundary layer and lower precipitation, respectively, compared to the rest of the seasons. Number concentrations of particles smaller than 500 nm have a mean of 9.2 x 10(3) particles cm(-3) and standard deviation 4.9x10(3) particles cm(-3), exhibiting an increasing trend between 2008 and 2011 and a decreasing trend from 2013 to 2015. The particle number concentrations exhibit highest values in spring and summer (despite the increased precipitation) due to the high occurrence of nucleation-mode particles, which most likely are formed elsewhere and are transported to the observation station. Particle hygroscopicity measurements show that, independently of the air mass origin, the particles are mostly externally mixed with the more hydrophobic mode having a mean hygroscopic parameter kappa of 0.1 while for the more hydrophilic mode kappa is 0.35. The hygroscopicity of the smaller particles investigated in this work (i.e., particles having diameters of 35 nm) appears to increase during the course of the nucleation events, reflecting a change in the chemical composition of the particles. (C) 2017 Elsevier B.V. All rights reserved.Peer reviewe

    Detailed electronic structure studies on superconducting MgB2_2 and related compounds

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    In order to understand the unexpected superconducting behavior of MgB2_2 compound we have made electronic structure calculations for MgB2_2 and closely related systems. Our calculated Debye temperature from the elastic properties indicate that the average phonon frequency is very large in MgB2_2 compared with other superconducting intermetallics and the exceptionally high TcT_c in this material can be explained through BCS mechanism only if phonon softening occurs or the phonon modes are highly anisotropic. We identified a doubly-degenerate quasi-two dimensional key-energy band in the vicinity of EFE_{F} along Γ\Gamma-A direction of BZ which play an important role in deciding the superconducting behavior of this material. Based on this result, we have searched for similar kinds of electronic feature in a series of isoelectronic compounds such as BeB2_2, CaB2_2, SrB2_2, LiBC and MgB2_2C2_2 and found that MgB2_2C2_2 is one potential material from the superconductivity point of view. There are contradictory experimental results regarding the anisotropy in the elastic properties of MgB2_2 ranging from isotropic, moderately anisotropic to highly anisotropic. In order to settle this issue we have calculated the single crystal elastic constants for MgB2_2 by the accurate full-potential method and derived the directional dependent linear compressibility, Young's modulus, shear modulus and relevant elastic properties. We have observed large anisotropy in the elastic properties. Our calculated polarized optical dielectric tensor shows highly anisotropic behavior even though it possesses isotropic transport property. MgB2_2 possesses a mixed bonding character and this has been verified from density of states, charge density and crystal orbital Hamiltonian population analyses

    The Evolution of Bat Vestibular Systems in the Face of Potential Antagonistic Selection Pressures for Flight and Echolocation

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    PMCID: PMC3634842This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

    Qualitative Evaluation of Common Quantitative Metrics for Clinical Acceptance of Automatic Segmentation:a Case Study on Heart Contouring from CT Images by Deep Learning Algorithms

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    Organs-at-risk contouring is time consuming and labour intensive. Automation by deep learning algorithms would decrease the workload of radiotherapists and technicians considerably. However, the variety of metrics used for the evaluation of deep learning algorithms make the results of many papers difficult to interpret and compare. In this paper, a qualitative evaluation is done on five established metrics to assess whether their values correlate with clinical usability. A total of 377 CT volumes with heart delineations were randomly selected for training and evaluation. A deep learning algorithm was used to predict the contours of the heart. A total of 101 CT slices from the validation set with the predicted contours were shown to three experienced radiologists. They examined each slice independently whether they would accept or adjust the prediction and if there were (small) mistakes. For each slice, the scores of this qualitative evaluation were then compared with the Sørensen-Dice coefficient (DC), the Hausdorff distance (HD), pixel-wise accuracy, sensitivity and precision. The statistical analysis of the qualitative evaluation and metrics showed a significant correlation. Of the slices with a DC over 0.96 (N = 20) or a 95% HD under 5 voxels (N = 25), no slices were rejected by the readers. Contours with lower DC or higher HD were seen in both rejected and accepted contours. Qualitative evaluation shows that it is difficult to use common quantification metrics as indicator for use in clinic. We might need to change the reporting of quantitative metrics to better reflect clinical acceptance

    Identification and Characterization of a Small Molecule that Activates Thiosulfate Sulfurtransferase and Stimulates Mitochondrial Respiration

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    The enzyme Thiosulfate sulfurtransferase (TST, EC 2.8.1.1), is a positive genetic predictor of diabetes type 2 and obesity. As increased TST activity protects against the development of diabetic symptoms in mice, an activating compound for TST may provide therapeutic benefits in diabetes and obesity. We identified a small molecule activator of human TST through screening of an inhouse small molecule library. Kinetic studies in vitro suggest that two distinct isomers of the compound are required for full activation as well as an allosteric mode of activation. Additionally, we studied the effect of TST protein and the activator on TST activity through mitochondrial respiration. Molecular docking and molecular dynamics (MD) approaches supports an allosteric site for the binding of the activator, which is supported by the lack of activation in the E. coli. mercaptopyruvate sulfurtransferase. Finally, we show that increasing TST activity in isolated mitochondria increases mitochondrial oxygen consumption. This article is protected by copyright. All rights reserved.</p

    Functional Implications of Ubiquitous Semicircular Canal Non-Orthogonality in Mammals

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    The ‘canonical model’ of semicircular canal orientation in mammals assumes that 1) the three ipsilateral canals of an inner ear exist in orthogonal planes (i.e., orthogonality), 2) corresponding left and right canal pairs have equivalent angles (i.e., angle symmetry), and 3) contralateral synergistic canals occupy parallel planes (i.e., coplanarity). However, descriptions of vestibular anatomy that quantify semicircular canal orientation in single species often diverge substantially from this model. Data for primates further suggest that semicircular canal orthogonality varies predictably with the angular head velocities encountered in locomotion. These observations raise the possibility that orthogonality, symmetry, and coplanarity are misleading descriptors of semicircular canal orientation in mammals, and that deviations from these norms could have significant functional consequences. Here we critically assess the canonical model of semicircular canal orientation using high-resolution X-ray computed tomography scans of 39 mammal species. We find that substantial deviations from orthogonality, angle symmetry, and coplanarity are the rule for the mammals in our comparative sample. Furthermore, the degree to which the semicircular canals of a given species deviate from orthogonality is negatively correlated with estimated vestibular sensitivity. We conclude that the available comparative morphometric data do not support the canonical model and that its overemphasis as a heuristic generalization obscures a large amount of functionally relevant variation in semicircular canal orientation between species.Funding for this research was provided by grants NSFIIS-0208675 (http://www.nsf.gov/cise/iis/hcc_pgm.jsp), and EAR-0948842 (http://www.nsf.gov/awards/award_visualiz​ation.jsp?org=EAR). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Geological SciencesAnthropologyEmail: [email protected]

    Estimating Omissions from Searches

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    The mark-recapture method was devised by Petersen in 1896 to estimate the number of fish migrating into the Limfjord, and independently by Lincoln in 1930 to estimate waterfowl abundance. The technique applies to any search for a finite number of items by two or more people or agents, allowing the number of searched-for items to be estimated. This ubiquitous problem appears in fields from ecology and epidemiology, through to mathematics, social sciences, and computing. Here we exactly calculate the moments of the hypergeometric distribution associated with this long-standing problem, confirming that widely used estimates conjectured in 1951 are often too small. Our Bayesian approach highlights how different search strategies will modify the estimates. As an example, we assess the accuracy of a systematic literature review, an application we recommend.Comment: One figure. Supplementary Material included as an Appendi
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