329 research outputs found
Bubbly two-phase flow in hydraulic jumps at large Froude numbers
A hydraulic jump is a sudden, rapid transition from a supercritical flow to a subcritical flow. At large inflow Froude numbers, the jump is characterized by a significant amount of entrained air. For this paper, the bubbly two-phase flow properties of steady and strong hydraulic jumps were investigated experimentally. The results demonstrate that the strong air entrainment rate and the depth-averaged void-fraction data highlight a rapid deaeration of the jump roller. The results suggest that the hydraulic jumps are effective aerators and that the rate of detrainment is comparatively smaller at the largest Froude numbers. © 2011 American Society of Civil Engineers
Accurate detection of acute sleep deprivation using a metabolomic biomarker—A machine learning approach
Sleep deprivation enhances risk for serious injury and fatality on the roads and in workplaces. To facilitate future management of these risks through advanced detection, we developed and validated a metabolomic biomarker of sleep deprivation in healthy, young participants, across three experiments. Bi-hourly plasma samples from 2 × 40-hour extended wake protocols (for train/test models) and 1 × 40-hour protocol with an 8-hour overnight sleep interval were analyzed by untargeted liquid chromatography–mass spectrometry. Using a knowledge-based machine learning approach, five consistently important variables were used to build predictive models. Sleep deprivation (24 to 38 hours awake) was predicted accurately in classification models [versus well-rested (0 to 16 hours)] (accuracy = 94.7%/AUC 99.2%, 79.3%/AUC 89.1%) and to a lesser extent in regression (R2 = 86.1 and 47.8%) models for within- and between-participant models, respectively. Metabolites were identified for replicability/future deployment. This approach for detecting acute sleep deprivation offers potential to reduce accidents through “fitness for duty” or “post-accident analysis” assessments
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Reply to a comment on the article: Conditional Exceedance Probabilities. Monthly Weather Review 135 (2010), 363–372 (available in Academic Commons at http://dx.doi.org/10.7916/D8PK0G2S)
The calibration of the Sudbury Neutrino Observatory using uniformly distributed radioactive sources
The production and analysis of distributed sources of 24Na and 222Rn in the
Sudbury Neutrino Observatory (SNO) are described. These unique sources provided
accurate calibrations of the response to neutrons, produced through
photodisintegration of the deuterons in the heavy water target, and to low
energy betas and gammas. The application of these sources in determining the
neutron detection efficiency and response of the 3He proportional counter
array, and the characteristics of background Cherenkov light from trace amounts
of natural radioactivity is described.Comment: 24 pages, 13 figure
A Rapid Assessment of the Quality of Neonatal Healthcare in Kilimanjaro Region, Northeast Tanzania.
While child mortality is declining in Africa there has been no evidence of a comparable reduction in neonatal mortality. The quality of inpatient neonatal care is likely a contributing factor but data from resource limited settings are few. The objective of this study was to assess the quality of neonatal care in the district hospitals of the Kilimanjaro region of Tanzania. Clinical records were reviewed for ill or premature neonates admitted to 13 inpatient health facilities in the Kilimanjaro region; staffing and equipment levels were also assessed. Among the 82 neonates reviewed, key health information was missing from a substantial proportion of records: on maternal antenatal cards, blood group was recorded for 52 (63.4%) mothers, Rhesus (Rh) factor for 39 (47.6%), VDRL for 59 (71.9%) and HIV status for 77 (93.1%). From neonatal clinical records, heart rate was recorded for3 (3.7%) neonates, respiratory rate in 14, (17.1%) and temperature in 33 (40.2%). None of 13 facilities had a functioning premature unit despite calculated gestational age <36 weeks in 45.6% of evaluated neonates. Intravenous fluids and oxygen were available in 9 out of 13 of facilities, while antibiotics and essential basic equipment were available in more than two thirds. Medication dosing errors were common; under-dosage for ampicillin, gentamicin and cloxacillin was found in 44.0%, 37.9% and 50% of cases, respectively, while over-dosage was found in 20.0%, 24.2% and 19.9%, respectively. Physician or assistant physician staffing levels by the WHO indicator levels (WISN) were generally low. Key aspects of neonatal care were found to be poorly documented or incorrectly implemented in this appraisal of neonatal care in Kilimanjaro. Efforts towards quality assurance and enhanced motivation of staff may improve outcomes for this vulnerable group
Application of the Shiono and Knight Method in asymmetric compound channels with different side slopes of the internal wall
The Shiono and Knight Method (SKM) is widely used to predict the lateral distribution of depth-averaged velocity and boundary shear stress for flows in compound channels. Three calibrating coefficients need to be estimated for applying the SKM, namely eddy viscosity coefficient (λ), friction factor (f) and secondary flow coefficient (k). There are several tested methods which can satisfactorily be used to estimate λ, f. However, the calibration of secondary flow coefficients k to account for secondary flow effects correctly is still problematic. In this paper, the calibration of secondary flow coefficients is established by employing two approaches to estimate correct values of k for simulating asymmetric compound channel with different side slopes of the internal wall. The first approach is based on Abril and Knight (2004) who suggest fixed values for main channel and floodplain regions. In the second approach, the equations developed by Devi and Khatua (2017) that relate the variation of the secondary flow coefficients with the relative depth (β) and width ratio (α) are used. The results indicate that the calibration method developed by Devi and Khatua (2017) is a better choice for calibrating the secondary flow coefficients than using the first approach which assumes a fixed value of k for different flow depths. The results also indicate that the boundary condition based on the shear force continuity can successfully be used for simulating rectangular compound channels, while the continuity of depth-averaged velocity and its gradient is accepted boundary condition in simulations of trapezoidal compound channels. However, the SKM performance for predicting the boundary shear stress over the shear layer region may not be improved by only imposing the suitable calibrated values of secondary flow coefficients. This is because difficulties of modelling the complex interaction that develops between the flows in the main channel and on the floodplain in this region
Application of the Shiono and Knight Method in asymmetric compound channels with different side slopes of the internal wall
The Shiono and Knight Method (SKM) is widely used to predict the lateral distribution of depth-averaged velocity and boundary shear stress for flows in compound channels. Three calibrating coefficients need to be estimated for applying the SKM, namely eddy viscosity coefficient (λ), friction factor (f) and secondary flow coefficient (k). There are several tested methods which can satisfactorily be used to estimate λ, f. However, the calibration of secondary flow coefficients k to account for secondary flow effects correctly is still problematic. In this paper, the calibration of secondary flow coefficients is established by employing two approaches to estimate correct values of k for simulating asymmetric compound channel with different side slopes of the internal wall. The first approach is based on Abril and Knight (2004) who suggest fixed values for main channel and floodplain regions. In the second approach, the equations developed by Devi and Khatua (2017) that relate the variation of the secondary flow coefficients with the relative depth (β) and width ratio (α) are used. The results indicate that the calibration method developed by Devi and Khatua (2017) is a better choice for calibrating the secondary flow coefficients than using the first approach which assumes a fixed value of k for different flow depths. The results also indicate that the boundary condition based on the shear force continuity can successfully be used for simulating rectangular compound channels, while the continuity of depth-averaged velocity and its gradient is accepted boundary condition in simulations of trapezoidal compound channels. However, the SKM performance for predicting the boundary shear stress over the shear layer region may not be improved by only imposing the suitable calibrated values of secondary flow coefficients. This is because difficulties of modelling the complex interaction that develops between the flows in the main channel and on the floodplain in this region
What Can We Conclude from Death Registration? Improved Methods for Evaluating Completeness
Julie Rajaratnam and colleagues evaluate the performance of a suite of demographic methods that estimate the fraction of deaths registered and counted by civil registration systems, and identify three variants that generally perform the best
Hydraulics of skimming flows on stepped chutes: The effects of inflow conditions?
Modern stepped spillways are typically designed for large discharge capacities corresponding to a skimming flow regime for which flow resistance is predominantly form drag. The writer demonstrates that the inflow conditions have some effect on the skimming flow properties. Boundary layer calculations show that the flow properties at inception of free-surface aeration are substantially different with pressurized intake. The re-analysis of experimental results highlights that the equivalent Darcy friction factor is f similar to 0.2 in average on uncontrolled stepped Chute and f similar to 0.1 on stepped chute with pressurized intake. A simple design chart is presented to estimate the residual flow velocity, and the agreement of the calculations with experimental results is deemed satisfactory for preliminary design
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