Determination of optimal cryoprotectant agents for 3D cell-based products cryopreservation by slow freezing

183 p.En esta tesis doctoral, se describen y se determinan los crioprotectores clave para la preservación de productos celulares 3D mediante la congelación lenta. Para ello, se han llevado a cabo los siguientes estudios: (i) determinación de crioprotectores óptimos para la congelación lenta de productos celulares 3D que proporciona mejores funciones celulares e integridades que el dimetilsulfoxido tras la descongelación, utilizando células encapsuladas como modelo de estudio; (ii) investigar el hialurónico como crioprotector natural alternativo para la congelación lenta de productos celulares 3D, utilizando las células encapsuladas como modelo de estudio; (iii) el estudio post-congelación de un producto celular clínico, formado de líquido sinovial y plasma rico en plaquetas, donde el ácido hialurónico puede actuar como un crioprotector natural.NanoBioCe

Aranburu Urtasun, Mikel : Niebla y cristal. Una historia del txistu y de los txistularis

Reseña y crítica del libro del folclorista navarro Mikel Aranburu que traza en cinco capítulos una sumaria exposición de la vida del txistu y el tamboril

Control methodologies of energy performance certificates. Data quality assessment in the Basque Country and learning from experience to make improvements

304 p.The EPBDs required Member States (MSs) to establish an independent control system for the EPC. The Basque Country has its own system. The Laboratory for the Quality Control in Buildings (LCCE- for its acronym in Spanish) of the Basque Government is one of the accredited bodies for performing the control activity. It is from the laboratory numerous EPCs checks have been carried out for this thesis.Despite initiatives to improve the quality of the EPCs, studies have shown that the inaccuracy of many of them is a fact. Without measures to enhance the EPCs quality, public distrust in European strategy could raise and the continuity of this could be at risk.In consequence, in order to get better quality results in EPC database, this thesis aims to contribute improving the Basque Country independent control system and making the control procedures implementation more effective. For that purpose, it is necessary to learn from previous experience, to know the effectiveness of the system and to observe where there is potential to improvement. Hence, a continuous and iterative methodology has been adopted in this thesis. After exposing the control performance of EPCs (Chapter 3), an exhaustive analysis of control results has been realized in order to obtain the feedback of the experience (Chapter 4, 5 and 6) and finally, some improvements proposalshave been exposed. At first, in Chapter 3, an overview of the control campaign in the 2014-2019 period has been presented. The control protocol stablished by LCCE, which is based on documentary review and on-site inspections,has been carried out in numerous EPCs and from them control results data have been collected in arepresentative 146 EPC sample.After that, an accurate analysis of collected data has been performed in three parts. In the first part(Chapter 4), the EPC sample quality is assessed, and a statistical analysis has made possible toextrapolate sample results to the Basque Country EPC database. The results obtained prove that not only in accuracy exists but also there is an increasing trend. Nevertheless, approximately as many EPCs presenta positive deviation as EPCs have a negative one. It suggests that at least half of EPCs were not madedeliberately by wrongdoing.In the second part (Chapter 5), an assessment of EPC subsamples data quality has been carried out. Bythis study, some guidance for the most effective EPC control selection criteria have been achieved. It isimpossible to control 100% of the EPCs, so it is necessary to have a selection criterion capable offiltering out the EPCs with most of the errors. The results suggest that the EPCs with the highest nrPEC(e.g. existing buildings or tertiary building) have the poorer quality. Moreover, it has been shown that theautomatic checks methodology could be an effective way to filtering EPCs with potential errors.The last part of the monitored EPC control analysis is focused on the qualitative, quantitative, and mixed research of non conformities (NCs) issued in non compliance reports. The analysis is carried out bycataloguing the type of NCs, exploring what underlies these NCs and what are the most appropriate and optimal ways to identify them. Several conclusions have been achieved, but two of them are worth mentioning. The NCs mainly occur given that qualified experts (QEs) fail in getting accurate data from project definition, from information exchange with project/construction management agents, etc as well as because EPCs are sometimes ill-defined. And the second main conclusion, is that there is not a single detection form which is able to detect the most part of the NC types. A combination of different checking procedures is needed to get an effective control methodology. Finally (Chapter 7), after the completion of the EPC control results analysis, this thesis has proposed various improvements for the system and verification procedures which are supported by conclusions of the previous chapter 4, 5 and 6. A preventive phase where the attachment of some documents will be required at the start of EPC registration in order to avoid some specific NCs is proposed. Besides, a new selection criterion is suggested based on a combination of a filtering by automatic checks and targeted criteria. At the end, organization of various steps in the verification protocol for controllers must be planned. Part of the last two measures consist of an automatic check-up program. Thus, validation rules for this aim have been determined. With the last chapter a continuous-iterative procedure is proposed. Never the less, it is necessary to make clear that a continuous improvement involves initiating again the procedure with the future control resultsand new regulations

Amistad: una relación de empoderamiento

En una jornada que tiene como fin ayudar a los alumnos a pensar sobre su futuro profesional reflexionando sobre sí mismos y sus habilidades, la amistad aparece como una relación de enorme potencial, como una relación empoderadora. Más allá de ser un factor imprescindible en una vida feliz y satisfactoria, la amistad es campo de cultivo natural para el desarrollo de muchas cualidades personales, de habilidades emocionales y sociales y sobre todo es una relación de enorme potencial social y creativo. Muchas grandes obras son obras de amistad (la Bauhaus, The Inklings, la Generación del 27, Apple y Microsoft empiezan entre amigos…), pues la amistad como tal no solo suma valores, sino que “los hace reaccionar”. La amistad lleva más allá de las posibilidades individuales, multiplica la capacidad y la propia realidad; tiene efecto multiplicador. Además, entre los amigos, como resultado de ese encuentro, surge la novedad, la idea que antes no había y el proyecto que antes no existía: en ese sentido, la amistad es creativa. ¿En qué consiste la verdadera amistad?, ¿es desinteresada? ¿dura siempre o tiene fecha de caducidad? ¿Cómo son las amistades en la red? ¿Cuáles son sus pilares y “polillas”? Reflexionar sobre las cosas ayuda a vivirlas mejor, reflexionar es un modo de vivir.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Melchor de Macanaz y sus Reflexiones y avisos para el govierno de la Monarquía de España. Actualidad del mensaje de un político del siglo XVIII

En aquest text es tracta la transcripció i l'edició d'un text desconegut de Melcior de Macanaz escrit al final de la seva vida a manera de «testament polític» i en el qual explica com hauria de procedir el rei per a aconseguir les majors quotes de desenvolupament econòmic i polític del regne i evitar els vicis introduïts.The article analyses the transcription and editing of a previously unknown text by Melchor de Macanaz, written towards the end of his life as a sort of political testament. The text describes how the monarch should proceed in order to achieve the kingdoms highest possible levels of economic and political development and avoid the existing defects.En este texto se aborda la transcripción y edición de un texto desconocido de Melchor de Macanaz escrito hacia el final de su vida a modo de «testamento político» y en el que explica como tendría que proceder el rey para alcanzar las mayores cotas de desarrollo económico y político del Reino y evitar los vicios introducidos

Melchor de Macanaz y sus Reflexiones y avisos para el govierno de la Monarquía de España. Actualidad del mensaje de un político del siglo XVIII

En aquest text es tracta la transcripció i l'edició d'un text desconegut de Melcior de Macanaz escrit al final de la seva vida a manera de «testament polític» i en el qual explica com hauria de procedir el rei per a aconseguir les majors quotes de desenvolupament econòmic i polític del regne i evitar els vicis introduïts.The article analyses the transcription and editing of a previously unknown text by Melchor de Macanaz, written towards the end of his life as a sort of “political testament”. The text describes how the monarch should proceed in order to achieve the kingdom’s highest possible levels of economic and political development and avoid the existing defects.En este texto se aborda la transcripción y edición de un texto desconocido de Melchor de Macanaz escrito hacia el final de su vida a modo de «testamento político» y en el que explica como tendría que proceder el rey para alcanzar las mayores cotas de desarrollo económico y político del Reino y evitar los vicios introducidos

Genus 0 logarithmic and tropical fixed-domain counts for Hirzebruch surfaces

For a non-singular projective toric variety $X$, the virtual logarithmic Tevelev degrees are defined as the virtual degree of the morphism from the moduli stack of logarithmic stable maps $\overline{\mathcal{M}}_{\mathsf{\Gamma}}(X)$ to the product $\overline{\mathcal{M}}_{g,n} \times X^n$. In this paper, after proving the genus $0$ correspondence theorem in this setting, we use tropical methods to provide closed formulas for the case in which $X$ is a Hirzebruch surface. In order to do so, we explicitly list all the tropical curves contributing to the count.Comment: 24 page

Groundwater pollution in quaternary aquifer of Vitoria - Gasteiz (Basque Country, Spain)

As a result of diverse changes in land use and in water-resource management in the high basin of the Zadorra River (Basque Country), an important loss of water resources and an intense contamination by nitrogen compounds has taken place. The purpose of this paper is to detail the land transformations that have taken place on the aquifer since the 1950s: increase of drainage network, change from dry to irrigated farming, and diversion of rivers at the aquifer unit inlet. Furthermore, we analyze the impact of these transformations on the hydrodynamics and water quality of this aquifer system

Iniciativas para la introducción del sistema europeo de créditos : la experiencia de la asignatura "Introducción a la Contabilidad" en la Escuela Universitaria de Relaciones Laborales de la Universidad del País Vasco/EHU

Al objeto de impulsar la adaptación de la docencia a los ECTS, en 2004 la Universidad del País Vasco lanzó un plan bianual, de carácter voluntario, a desarrollar en dos fases. Una primera formativa (AICRE) y una segunda de implementación (SICRE). Este artículo describe la participación de la asignatura "Introducción de la Contabilidad" de la diplomatura en Relaciones Laborales en la primera experiencia de este plan y analiza brevemente la evolución de su rendimiento. La evaluación del plan por parte de los participantes a nivel de la universidad puso en evidencia algunas limitaciones que han tenido como consecuencia el diseño de un nuevo Programa (IBP) que implantará la metodología ECTS por cursos completos._______________________________In order to promote the teaching's adaptation to ECTS, in 2004 the University of The Basque Country launched a two-year planning to be developed voluntarily. First year for training (AICRE) and second for implementing (SICRE). In this paper, we describe this first experience concerning the `Accounting" course of Labour Relations degree and briefly analyse its performance over the time. The evaluation coming from university level participants exposed some limitations of AICRE-SICRE. As a consequence the University has designed a new programme named IBP in order to implement. the ECTS methodology on a student's complete academic year basis