Root architecture and rhizobial inoculation in relation to drought stress response in common bean (Phaseolus vulgaris l.)

The present study was aimed at assessing the root traits and rhizobial inoculation in relation to drought in common bean, Phaseolus vulgaris. Drought caused the largest decrease in shoot biomass followed by plant height, while an increase was recorded inroot/shoot ratio. Rhizobial inoculation caused largest increase in shoot biomass followed by root volume and root biomass and smallest increase in rooting depth. WB-216 and WB-185 had better rooting depth in all treatments. However, WB-83 (92.67) had highest rooting depth under irrigated conditions and SR-1 had highest rooting depth under irrigated conditions treated with rhizobium (108.50). Similarly, WB-216 had highest root/shoot ratio under drought (2.693) followed by WB-185 (1.285) while lowest value was recorded for Arka Anoop (0.373). In rhizobium treated drought condition, WB-216 recorded highest root/shoot ratio (5.540) followed by SFB-1 (1.967). Under irrigated conditions (both with and without rhizobium), WB-185 recorded highest root/shoot ratio while lowest was recorded for SR-1 (0.166). The mean squares due to root depth, root biomass and root volume were significant whereas the mean squares due to water and rhizobium were non-significant. Among interactions the genotype x water regime was significant for rooting depth (5 % level), genotype x rhizobia was significant for rooting depth and root volume (1 % level) and the interaction of genotype x water regime x rhizobium was significant for rooting depth, root biomass and root volume (1 % level). The results reinforce the need to further analyse the potential of other soil microbes in common bean rhizosphere in amelioration of the effects of water stress

Natural Variation for Seed Physical, Biochemical and Culinary traits in Common bean (Phaseolus vulgaris L.)

Twenty genotypes of common bean including 17 breeding lines were evaluated for various seed physical, nutritional and culinary traits viz., seed colour, seed shape, seed brilliance, seed coat pattern, seed length, seed breadth and seed weight, traits protein content, phytic acid, raffinose, water absorption percentage, coat percentage, swelling and hydration coefficient as well as cooking score. Most of the genotypes were kidney shaped with plain seed coat and medium seed brilliance. Among biochemical traits, highest protein content was recorded for  Arka Anoop (22.15 %) followed by WB-341 (21.45 %), WB-216 (21.16 %) and WB-249 (20.99).  Low phytic acid was recorded in WB-970 (0.440 %), WB-258 (0.968 %) and WB-102 (1.068 %).  Low values for raffinose was recorded for WB-102 (3.800 mg/g) followed by WB-482 (3.833 mg/g). Highest water absorption percentage was recorded for WB-249 (136.363), Arka Anoop (131.818) and SFB-1 (126.923). The swelling coefficient was highest in case of WB-642 (300.000), WB-249 (266.667) and WB-335 (250.000) whereas lowest values for swelling coefficient were recorded in case of WB-341 (114.285), WB-216 (145.454) and WB-1006 (124.554). Among correlations between various seed physical, biochemical and culinary traits, raffinose was positively and significantly correlated with phytic acid. Phytic acid was also significantly and positively correlated with protein, coat proportion and 100-seed weight. Coat proportion was negatively correlated water absorption percentage, swelling coefficient, hydration coefficient as well as cooking time score. Cooking time score was positively correlated with hydration and swelling coefficients as well as seed weight but negatively correlated with coat proportion.Â

Effects of Fertilizers on Copper and Nickel Accumulation and Human Health Risk Assessment of Vegetables and Food Crops

Despite the fact that fertilizers have been used for millennia for sustainable crop production, this high and considerable dependence on fertilizers heightens environmental concerns with the indirect human exposure due to accumulation of toxins in food chain via soil contamination. The purpose of this study is to evaluate the application of fertilizers to the soil and their effect on the accumulation of copper and nickel in spinach (Spinacia oleracea), garlic (Allium sativum), wheat (Triticum aestivum), maize (Zea mays), and barley (Hordeum vulgare); as well as potential health concerns associated with consuming vegetables cultivated on this contaminated land. Samples of available soil, food crops, and human blood were collected from three different Tehsils: Bhalwal, Sahiwal, and Silanwali and were regarded as site 1, site 2 and site 3 respectively. Urea, farmyard manure, and potassium chloride were delivered to Site 1; urea phosphate, manure, and ammonium sulphate were delivered to Site 2; and superphosphate, ammonium phosphate, and nitrate phosphate were delivered to Site 3. Data was subjected to statistical analysis for computing out ANOVA and correlation. Analysis revealed that minimum copper concentration was found in the soil of T. aestivum grown at Site-1 while the inhabitants of Site 3 had the highest concentration of Cu in their blood. The highest level of HIR was found in the human beings that ate the S. oleracea grown at Site 3. It is strongly advised that fertilizers be used sparingly, as their excessive use can cause human health risks

Variations in physico-chemical and antioxidant attributes of grape seed oil as function of extraction techniques

The aim of the current research work was to assess and compare the impact of two extraction techniques on the physico-chemical, and antioxidant parameters of grape seed oil (GSO). The GSO extracted by Soxhlet and Folch methods indicated a notable variation in the oil yield (8.58 % and 10.19%) and saponification value (196.35 and 189.33 mg of KOH g-1), respectively. However, no significant (p<0.05) variation was detected for density, acid value, refractive index, iodine no, unsaponifiable matter, and free fatty acids between the tested two oils. Meanwhile, the oil produced by Soxhlet method exhibited relatively a higher extent of unsaturated dienes, trienes, peroxide value, p-anisidine value, and thus poor oxidation state. A notable variation in the content of principal fatty acid (linoleic acid) was recorded between Folch extracted oil (70.11%) and Soxhlet extracted oil (66.57%). The contents of total tocopherols were noted to be considerably higher for Folch extracted oil (105.55 mg kg-1) than the Soxhlet extracted oil (73.70 mg kg-1). Among the individual phenolics analyzed by HPLC, gallic acid (14.02 mg kg-1) and caffeic acid (5.20 mg kg-1) were detected as major component in Folch extracted oil and Soxhlet extracted oil, respectively. The results of the present comparative study support that Folch method is relatively a good choice for the extraction of GSO with promising nutritive quality in terms of oxidation parameters, contents of linoleic acid and antioxidant phenolics

Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial

Background: Tranexamic acid reduces surgical bleeding and reduces death due to bleeding in patients with trauma. Meta-analyses of small trials show that tranexamic acid might decrease deaths from gastrointestinal bleeding. We aimed to assess the effects of tranexamic acid in patients with gastrointestinal bleeding. Methods: We did an international, multicentre, randomised, placebo-controlled trial in 164 hospitals in 15 countries. Patients were enrolled if the responsible clinician was uncertain whether to use tranexamic acid, were aged above the minimum age considered an adult in their country (either aged 16 years and older or aged 18 years and older), and had significant (defined as at risk of bleeding to death) upper or lower gastrointestinal bleeding. Patients were randomly assigned by selection of a numbered treatment pack from a box containing eight packs that were identical apart from the pack number. Patients received either a loading dose of 1 g tranexamic acid, which was added to 100 mL infusion bag of 0·9% sodium chloride and infused by slow intravenous injection over 10 min, followed by a maintenance dose of 3 g tranexamic acid added to 1 L of any isotonic intravenous solution and infused at 125 mg/h for 24 h, or placebo (sodium chloride 0·9%). Patients, caregivers, and those assessing outcomes were masked to allocation. The primary outcome was death due to bleeding within 5 days of randomisation; analysis excluded patients who received neither dose of the allocated treatment and those for whom outcome data on death were unavailable. This trial was registered with Current Controlled Trials, ISRCTN11225767, and ClinicalTrials.gov, NCT01658124. Findings: Between July 4, 2013, and June 21, 2019, we randomly allocated 12 009 patients to receive tranexamic acid (5994, 49·9%) or matching placebo (6015, 50·1%), of whom 11 952 (99·5%) received the first dose of the allocated treatment. Death due to bleeding within 5 days of randomisation occurred in 222 (4%) of 5956 patients in the tranexamic acid group and in 226 (4%) of 5981 patients in the placebo group (risk ratio [RR] 0·99, 95% CI 0·82–1·18). Arterial thromboembolic events (myocardial infarction or stroke) were similar in the tranexamic acid group and placebo group (42 [0·7%] of 5952 vs 46 [0·8%] of 5977; 0·92; 0·60 to 1·39). Venous thromboembolic events (deep vein thrombosis or pulmonary embolism) were higher in tranexamic acid group than in the placebo group (48 [0·8%] of 5952 vs 26 [0·4%] of 5977; RR 1·85; 95% CI 1·15 to 2·98). Interpretation: We found that tranexamic acid did not reduce death from gastrointestinal bleeding. On the basis of our results, tranexamic acid should not be used for the treatment of gastrointestinal bleeding outside the context of a randomised trial

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial

SummaryBackground Azithromycin has been proposed as a treatment for COVID-19 on the basis of its immunomodulatoryactions. We aimed to evaluate the safety and efficacy of azithromycin in patients admitted to hospital with COVID-19.Methods In this randomised, controlled, open-label, adaptive platform trial (Randomised Evaluation of COVID-19Therapy [RECOVERY]), several possible treatments were compared with usual care in patients admitted to hospitalwith COVID-19 in the UK. The trial is underway at 176 hospitals in the UK. Eligible and consenting patients wererandomly allocated to either usual standard of care alone or usual standard of care plus azithromycin 500 mg once perday by mouth or intravenously for 10 days or until discharge (or allocation to one of the other RECOVERY treatmentgroups). Patients were assigned via web-based simple (unstratified) randomisation with allocation concealment andwere twice as likely to be randomly assigned to usual care than to any of the active treatment groups. Participants andlocal study staff were not masked to the allocated treatment, but all others involved in the trial were masked to theoutcome data during the trial. The primary outcome was 28-day all-cause mortality, assessed in the intention-to-treatpopulation. The trial is registered with ISRCTN, 50189673, and ClinicalTrials.gov, NCT04381936.Findings Between April 7 and Nov 27, 2020, of 16 442 patients enrolled in the RECOVERY trial, 9433 (57%) wereeligible and 7763 were included in the assessment of azithromycin. The mean age of these study participants was65·3 years (SD 15·7) and approximately a third were women (2944 [38%] of 7763). 2582 patients were randomlyallocated to receive azithromycin and 5181 patients were randomly allocated to usual care alone. Overall,561 (22%) patients allocated to azithromycin and 1162 (22%) patients allocated to usual care died within 28 days(rate ratio 0·97, 95% CI 0·87–1·07; p=0·50). No significant difference was seen in duration of hospital stay (median10 days [IQR 5 to >28] vs 11 days [5 to >28]) or the proportion of patients discharged from hospital alive within 28 days(rate ratio 1·04, 95% CI 0·98–1·10; p=0·19). Among those not on invasive mechanical ventilation at baseline, nosignificant difference was seen in the proportion meeting the composite endpoint of invasive mechanical ventilationor death (risk ratio 0·95, 95% CI 0·87–1·03; p=0·24).Interpretation In patients admitted to hospital with COVID-19, azithromycin did not improve survival or otherprespecified clinical outcomes. Azithromycin use in patients admitted to hospital with COVID-19 should be restrictedto patients in whom there is a clear antimicrobial indication

اکیسویں صدی کے تقاضے اور فکرِ اقبال

Dr. Allama Muhammad Iqbal is considred one of the most important figures in Urdu literature with literary work in both Urdu and Persian. He is also highly acclaimed Muslim philosophical thinker of modern times. Along with his Urdu and persian poetry,his Urdu and English lectures and letters have been very influential in cultural, social, religious and political disputes. Iqbal,s famous lectures on different aspects of islamic philosophy, which he delivered at Madraas and Aligarh, brought a revolution in the thinking of muslims. Iqbal quoted as Poet of East by academics and institutions and media. Iqbal is not only the poet of East, actually he is a universal poet. Iqbal is not restructed to any specific segment of the world community but he is for the entire humanity

اردو شاعرات کی نظموں میں اساطیری حوالے

A myth is any traditional story consisting of evevts that are ostensibly historical,though often supernatural,explaining the origins of cultural practice or natural phenomenon.urdu literature, deeply influnced by islamic and Hindu myths. We can not understand the literature like aag ka drya s first portion and most of intzar hussain s short stories untill we have knowledge about myth.In urdu poems,poet also use myths /asateer.A myth is a sacred narrative because it holds religious or spiritual significance for those who telll it

A descriptive study of gender inequality in proverbs of mewati language

AbstractLanguage performs a variety of functions and specifically it acts as a primary vehicle for transmitting cultural norms, values and expectations even the thought paradigms from one generation to another. Language is a mirror which reflects the past of a society, and chronicles of history testify to this claim. The essentials and crystallization of a culture’s norms and conventions are recorded through its proverbs and platitudes. Through proverbs, we can get deep insight into lifestyle, ethical standards and socio-cultural norms of a particular locality or society. This research intends to explore the contribution of proverbs from Mewati language in the development of gender inequality and ambivalence in Mewati society. A sample consisting of gender-related proverbs from Mewati language has been selected. Selected proverbs have been translated and transcribed in English Language; then are categorized and interpreted with the relevance to genders and their roles in constructing the gender inequality in the society. Ambivalent Sexism Theory has been applied to the selected proverbs. The findings of the study reveal that proverbs from Mewati language portray men positively, whereas the women are portrayed either in a misogynist manner or ambivalently suppressing their positivity, uniqueness and intellect. The research is anticipated to motivate future researchers to conduct further research on Mewati cultural and folk discourse to draw attention towards the significance of equal treatment of both genders, and to introduce gender equality reforms within the Mewati community

سرسید احمد خان اورعلامہ اقبال کی ذہنی ہم آہنگی

Sir Syed Ahmed Khan and Allama Iqbal are great leaders of Indian Muslims. They were the pioneers of the freedom movement of sub-continent. Both visited abroad and their Intellectual thinking was similar. They believed in "Two Nations Theory" and were convinced that the solution of Indian Muslim's problems was in a separate country consisting of Muslim majority provinces and states of India, where they will be free to practice Islam and to achieve this destiny they encouraged Muslims of India to embrace modern education in addition to the Islamic Education. In 1903 Iqbal wrote the poem "Syed ki Lohe Turbat" which reveals his relations with Sir Syed. Since his early days Iqbal was influenced by Sir Syed Ahmed's movement and later, he participated and completed Sir Syed's mission by his tireless efforts