Fluid‐driven tensile fracture and fracture toughness in Nash Point shale at elevated pressure

A number of key processes, both natural and anthropogenic, involve the fracture of rocks subjected to tensile stress, including vein growth and mineralization, and the extraction of hydrocarbons through hydraulic fracturing. In each case, the fundamental material property of mode‐I fracture toughness must be overcome in order for a tensile fracture to propagate. While measuring this parameter is relatively straightforward at ambient pressure, estimating fracture toughness of rocks at depth, where they experience confining pressure, is technically challenging. Here we report a new analysis that combines results from thick‐walled cylinder burst tests with quantitative acoustic emission to estimate the mode‐I fracture toughness (K_{Ic}) of Nash Point Shale at confining pressure simulating in situ conditions to approximately 1‐km depth. In the most favorable orientation, the pressure required to fracture the rock shell (injection pressure, P_{inj}) increases from 6.1 MPa at 2.2‐MPa confining pressure (P_{c}), to 34 MPa at 20‐MPa confining pressure. When fractures are forced to cross the shale bedding, the required injection pressures are 30.3 MPa (at P_{c} = 4.5MPa) and 58 MPa (P_{c} = 20 MPa), respectively. Applying the model of Abou‐Sayed et al. (1978, https://doi.org/10.1029/JB083iB06p02851) to estimate the initial flaw size, we calculate that this pressure increase equates to an increase in K_{Ic} from 0.36 to 4.05 MPa·m^{1/2} as differential fluid pressure (P_{inj} - P_{c}) increases from 3.2 to 22.0 MPa. We conclude that the increasing pressure due to depth in the Earth will have a significant influence on fracture toughness, which is also a function of the inherent anisotropy

Mobile phone use and glioma risk: comparison of epidemiological study results with incidence trends in the United States

Objective In view of mobile phone exposure being classified as a possible human carcinogen by the International Agency for Research on Cancer (IARC), we determined the compatibility of two recent reports of glioma risk (forming the basis of the IARC’s classification) with observed incidence trends in the United States

Compact radio sources and jet-driven AGN feedback in the early Universe: Constraints from integral-field spectroscopy

To investigate the impact of radio jets during the formation epoch of their massive host galaxies, we present an analysis of two massive, log(M_stel/ M_sun)~10.6 and 11.3, compact radio galaxies at z=3.5, TNJ0205+2242 and TNJ0121+1320. Their small radio sizes (R<= 10 kpc) are most likely a sign of youth. We compare their radio properties and gas dynamics with those in well extended radio galaxies at high redshift, which show strong evidence for powerful, jet-driven outflows of significant gas masses (M 10^9-10 M_sun). Our analysis combines rest-frame optical integral-field spectroscopy with existing radio imaging, CO emission line spectra, and rest-frame UV spectroscopy. [OIII]5007 line emission is compact in both galaxies and lies within the region defined by the radio lobes. For TNJ0205+2242, the Ly-alpha profile narrows significantly outside the jet radius, indicating the presence of a quiescent halo. TNJ0121+1320 has two components separated by ~10 kpc and a velocity offset of ~300 km s^-1. If motions are gravitational, this implies a dynamical mass of 2x10^11 M_sun for the more massive, radio-loud component. The dynamical mass, molecular gas mass measured from the CO line emission, and radio luminosity of these two compact radio galaxies imply that compact radio sources may well develop large-scale, energetic outflows as observed in extended radio galaxies, with the potential of removing significant fractions of the ISM from the host galaxy. The absence of luminous emission line gas extending beyond the radio emission in these sources agrees with the observed timescales and outflow rates in extended radio galaxies, and adds further evidence that the energetic, large-scale outflows observed in extended radio sources (Nesvadba et al. 2006) are indeed the result of influence of the radio jet.Comment: A&A accepte

The heating mechanism for the warm/cool dust in powerful, radio-loud AGN

The uncertainty surrounding the nature of the heating mechanism for the dust that emits at mid- to far-IR (MFIR) wavelengths in active galaxies limits our understanding of the links between active galactic nuclei (AGN) and galaxy evolution, as well as our ability to interpret the prodigious infrared and sub-mm emission of some of the most distant galaxies in the Universe. Here we report deep Spitzer observations of a complete sample of powerful, intermediate redshift (0.05 < z < 0.7) radio galaxies and quasars. We show that AGN power, as traced by [OIII]5007 emission, is strongly correlated with both the mid-IR (24 micron) and the far-IR (70 micron) luminosities, however, with increased scatter in the 70 micron correlation. A major cause of this increased scatter is a group of objects that falls above the main correlation and displays evidence for prodigious recent star formation activity at optical wavelengths, along with relatively cool MFIR colours. These results provide evidence that illumination by the AGN is the primary heating mechanism for the dust emitting at both 24 and 70 microns, with starbursts dominating the heating of the cool dust in only 20 -- 30% of objects. This implies that powerful AGN are not always accompanied by the type of luminous starbursts that are characteristic of the peak of activity in major gas-rich mergers.Comment: 13 pages, 3 figures. Accepted for publication in astrophysical journal letter

How do women prepare for pregnancy? Preconception experiences of women attending antenatal services and views of health professionals

Copyright: © 2014 Stephenson et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Main objective - To determine the extent to which women plan and prepare for pregnancy. Methods - Cross-sectional questionnaire survey of pregnant women attending three maternity services in London about knowledge and uptake of preconception care; including a robust measure of pregnancy planning, and phone interviews with a range of health care professionals. Main results - We recruited 1173/1288 (90%) women, median age of 32 years. 73% had clearly planned their pregnancy, 24% were ambivalent and only 3% of pregnancies were unplanned. 51% of all women and 63% of those with a planned pregnancy took folic acid before pregnancy. 21% of all women reported smoking and 61% reported drinking alcohol in the 3 months before pregnancy; 48% of smokers and 41% of drinkers reduced or stopped before pregnancy. The 51% of all women who reported advice from a health professional before becoming pregnant were more likely to adopt healthier behaviours before pregnancy [adjusted odds ratios for greatest health professional input compared with none were 2.34 (95% confidence interval 1.54–3.54) for taking folic acid and 2.18 (95% CI 1.42–3.36) for adopting a healthier diet before pregnancy]. Interviews with 20 health professionals indicated low awareness of preconception health issues, missed opportunities and confusion about responsibility for delivery of preconception care. Significance of the findings - Despite a high level of pregnancy planning, awareness of preconception health among women and health professionals is low, and responsibility for providing preconception care is unclear. However, many women are motivated to adopt healthier behaviours in the preconception period, as indicated by halving of reported smoking rates in this study. The link between health professional input and healthy behaviour change before pregnancy is a new finding that should invigorate strategies to improve awareness and uptake of pre-pregnancy health care, and bring wider benefits for public health.Department of Healt

Toward Human-Carnivore Coexistence: Understanding Tolerance for Tigers in Bangladesh

Fostering local community tolerance for endangered carnivores, such as tigers (Panthera tigris), is a core component of many conservation strategies. Identification of antecedents of tolerance will facilitate the development of effective tolerance-building conservation action and secure local community support for, and involvement in, conservation initiatives. We use a stated preference approach for measuring tolerance, based on the ‘Wildlife Stakeholder Acceptance Capacity’ concept, to explore villagers’ tolerance levels for tigers in the Bangladesh Sundarbans, an area where, at the time of the research, human-tiger conflict was severe. We apply structural equation modeling to test an a priori defined theoretical model of tolerance and identify the experiential and psychological basis of tolerance in this community. Our results indicate that beliefs about tigers and about the perceived current tiger population trend are predictors of tolerance for tigers. Positive beliefs about tigers and a belief that the tiger population is not currently increasing are both associated with greater stated tolerance for the species. Contrary to commonly-held notions, negative experiences with tigers do not directly affect tolerance levels; instead, their effect is mediated by villagers’ beliefs about tigers and risk perceptions concerning human-tiger conflict incidents. These findings highlight a need to explore and understand the socio-psychological factors that encourage tolerance towards endangered species. Our research also demonstrates the applicability of this approach to tolerance research to a wide range of socio-economic and cultural contexts and reveals its capacity to enhance carnivore conservation efforts worldwide

Exploring the conformational dynamics of alanine dipeptide in solution subjected to an external electric field: A nonequilibrium molecular dynamics simulation

In this paper, we investigate the conformational dynamics of alanine dipeptide under an external electric field by nonequilibrium molecular dynamics simulation. We consider the case of a constant and of an oscillatory field. In this context we propose a procedure to implement the temperature control, which removes the irrelevant thermal effects of the field. For the constant field different time-scales are identified in the conformational, dipole moment, and orientational dynamics. Moreover, we prove that the solvent structure only marginally changes when the external field is switched on. In the case of oscillatory field, the conformational changes are shown to be as strong as in the previous case, and non-trivial nonequilibrium circular paths in the conformation space are revealed by calculating the integrated net probability fluxes.Comment: 23 pages, 12 figure

Engaging adolescents in changing behaviour (EACH-B): A study protocol for a cluster randomised controlled trial to improve dietary quality and physical activity

Background Poor diet and lack of physical activity are strongly linked to non-communicable disease risk, but modifying them is challenging. There is increasing recognition that adolescence is an important time to intervene; habits formed during this period tend to last, and physical and psychological changes during adolescence make it an important time to help individuals form healthier habits. Improving adolescents’ health behaviours is important not only for their own health now and in adulthood, but also for the health of any future children. Building on LifeLab—an existing, purpose-built educational facility at the University of Southampton—we have developed a multi-component intervention for secondary school students called Engaging Adolescents in Changing Behaviour (EACH-B) that aims to motivate and support adolescents to eat better and be more physically active. Methods A cluster randomised controlled trial is being conducted to evaluate the effectiveness of the EACH-B intervention. The primary outcomes of the intervention are self-reported dietary quality and objectively measured physical activity (PA) levels, both assessed at baseline and at 12-month follow-up. The EACH-B intervention consists of three linked elements: professional development for teachers including training in communication skills to support health behaviour change; the LifeLab educational module comprising in-school teaching of nine science lessons linked to the English National Curriculum and a practical day visit to the LifeLab facility; and a personalised digital intervention that involves social support and game features that promote eating better and being more active. Both the taught module and the LifeLab day are designed with a focus on the science behind the messages about positive health behaviours, such as diet and PA, for the adolescents now, in adulthood and their future offspring, with the aim of promoting personal plans for change. The EACH-B research trial aims to recruit approximately 2300 secondary school students aged 12–13 years from 50 schools (the clusters) from Hampshire and neighbouring counties. Participating schools will be randomised to either the control or intervention arm. The intervention will be run during two academic years, with continual recruitment of schools throughout the school year until the sample size is reached. The schools allocated to the control arm will receive normal schooling but will be offered the intervention after data collection for the trial is complete. An economic model will be developed to assess the cost-effectiveness of the EACH-B intervention compared with usual schooling. Discussion Adolescents’ health needs are often ignored and they can be difficult to engage in behaviour change. Building a cheap, sustainable way of engaging them in making healthier choices will benefit their long-term health and that of their future children. Trial registration ISRCTN 74109264. Registered on 30 August 2019. EACH-B is a cluster randomised controlled trial, funded by the National Institute for Health Research (RP-PG-0216-20004)

Childhood socioeconomic position and objectively measured physical capability levels in adulthood: a systematic review and meta-analysis

&lt;p&gt;&lt;b&gt;Background:&lt;/b&gt; Grip strength, walking speed, chair rising and standing balance time are objective measures of physical capability that characterise current health and predict survival in older populations. Socioeconomic position (SEP) in childhood may influence the peak level of physical capability achieved in early adulthood, thereby affecting levels in later adulthood. We have undertaken a systematic review with meta-analyses to test the hypothesis that adverse childhood SEP is associated with lower levels of objectively measured physical capability in adulthood.&lt;/p&gt; &lt;p&gt;&lt;b&gt;Methods and Findings:&lt;/b&gt; Relevant studies published by May 2010 were identified through literature searches using EMBASE and MEDLINE. Unpublished results were obtained from study investigators. Results were provided by all study investigators in a standard format and pooled using random-effects meta-analyses. 19 studies were included in the review. Total sample sizes in meta-analyses ranged from N = 17,215 for chair rise time to N = 1,061,855 for grip strength. Although heterogeneity was detected, there was consistent evidence in age adjusted models that lower childhood SEP was associated with modest reductions in physical capability levels in adulthood: comparing the lowest with the highest childhood SEP there was a reduction in grip strength of 0.13 standard deviations (95% CI: 0.06, 0.21), a reduction in mean walking speed of 0.07 m/s (0.05, 0.10), an increase in mean chair rise time of 6% (4%, 8%) and an odds ratio of an inability to balance for 5s of 1.26 (1.02, 1.55). Adjustment for the potential mediating factors, adult SEP and body size attenuated associations greatly. However, despite this attenuation, for walking speed and chair rise time, there was still evidence of moderate associations.&lt;/p&gt; &lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; Policies targeting socioeconomic inequalities in childhood may have additional benefits in promoting the maintenance of independence in later life.&lt;/p&gt