Some Contemporary Forms of the Funds of Knowledge Approach. Developing Culturally Responsive Pedagogy for Social Justice

The population of children in schools is rapidly becoming more ethnically and culturally diverse. However, there is a mismatch between the cultures in children’s homes and the cultures in their schools. The funds of knowledge approach emerged in Tucson (Arizona, USA) in order to counter the deficit perspectives common in depictions of working-class, Latin American families. In this paper we critically report on two contemporary research projects conducted around funds of knowledge and social justice pedagogy. In particular, this paper describes and discusses two projects, which have been conducted in schools with disadvantaged students in USA (Latino students in Arizona) and Australia (students with low socio-economic status, from diverse ethnic groups), examining how these projects exemplify social justice pedagogy. Both projects reviewed explore the application of a funds of knowledge approach, in which students focus on a key aspect of their identity and living circumstances and investigate it, seeking to understand the current situation and create positive options for possible improvements

Some Contemporary Forms of the Funds of Knowledge Approach. Developing Culturally Responsive Pedagogy for Social Justice

The population of children in schools is rapidly becoming more ethnically and culturally diverse. However, there is a mismatch between the cultures in children’s homes and the cultures in their schools. The funds of knowledge approach emerged in Tucson (Arizona, USA) in order to counter the deficit perspectives common in depictions of working-class, Latin American families. In this paper we critically report on two contemporary research projects conducted around funds of knowledge and social justice pedagogy. In particular, this paper describes and discusses two projects, which have been conducted in schools with disadvantaged students in USA (Latino students in Arizona) and Australia (students with low socio-economic status, from diverse ethnic groups), examining how these projects exemplify social justice pedagogy. Both projects reviewed explore the application of a funds of knowledge approach, in which students focus on a key aspect of their identity and living circumstances and investigate it, seeking to understand the current situation and create positive options for possible improvements

Identidad étnica entre los indígenas y los mestizos de la Universidad Intercultural de Chiapas

This study explored ethnic identity among 662 students (326 mestizos and 336 indigenous) from the Intercultural University of Chiapas (IUCh). Scholars suggest that ethnicity is more salient for ethnic minority adolescents than for adolescents who are members of the ethnic majority. The aims for this study were: 1) to determine the structure and validity of ethnic identity as measured by the Multigroup Ethnic Identity Measure in a sample of majority and minority ethnic groups from Intercultural University in Chiapas, and 2) to examine the variability of ethnic identity across ethnic groups. Specifically, it was hypothesized that the Multigroup Ethnic Identity Measure would show two factors, and that ethnic groups would differ on ethnic identity. The results supported the hypotheses.Este estudio explora la identidad étnica en un grupo de 662 estudiantes (326 mestizos y 336 indígenas) de la Universidad Intercultural de Chiapas (IUCh). Algunos autores señalan que la identidad étnica es más acusada en los adoles-centes que pertenecen a una minoría étnica que en los que son miembros de una mayoría étnica. Los objetivos de este trabajo fueron: 1) determinar la estructura y la validez de la Medida de Identidad Étnica Multigrupo en una muestra de grupos étnicos mayoritarios y minoritarios de la Universidad Intercultural de Chiapas y 2) estudiar la variabilidad de la identidad étnica entre ambos grupos. Concretamente, se postuló que se pueden distinguir dos factores en la Medida de Identidad Étnica Multigrupo y que ambos grupos diferirían significativamente en su identidad étnica. Los resultados apoyaron estas hipótesis

In the Era of mRNA Vaccines, Is There Any Hope for HIV Functional Cure?

Over 36 million people worldwide are infected with HIV. Antiretroviral therapy (ART) has proven to be highly effective to prevent HIV-1 transmission, clinical progression and death. Despite this success, the number of HIV-1 infected individuals continues increasing and ART should be taken for life. Therefore, there are two main priorities: the development of preventive vaccines to protect from HIV acquisition and achieve an efficient control of HIV infection in the absence of ART (functional cure). In this sense, in the last few years, there has been a broad interest in new and innovative approaches such as mRNA-based vaccines. RNA-based immunogens represent a promising alternative to conventional vaccines because of their high potency, capacity for rapid development and potential for low-cost manufacture and safe administration. Some mRNA-based vaccines platforms against infectious diseases have demonstrated encouraging results in animal models and humans. However, their application is still limited because the instability and inefficient in vivo delivery of mRNA. Immunogens, design, immunogenicity, chemical modifications on the molecule or the vaccine delivery methods are all crucial interventions for improvement. In this review we, will present the current knowledge and challenges in this research field. mRNA vaccines hold great promises as part of a combined strategy, for achieving HIV functional cure

Pressure-drop coefficients for cushioning system of hydraulic cylinder with grooved piston: a computational fluid dynamic simulation

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).Cushioning is an important aspect in hydraulic cylinder performance. The piston has to be decelerated before it strikes the end cap in order to avoid stresses in the cylinder components and reduce vibration that can be transmitted to the machine. One of the least-studied methods is internal cushioning by grooves in the piston. In this method, the flow is throttled with adequately designed grooves when the piston reaches the outlet port position. The purpose of the present work is to present a method to estimate the pressure-drop coefficients for a certain design of piston grooves in order to provide a model to develop a dynamic system simulation of the cushion system. The method is based on a computational fluid dynamic simulation of flow through piston grooves to the outlet port for each piston’s static position. The results are compared with experimental measurements, and a correction, based on Reynolds number, is proposed. Good agreement, below 16%, was obtained for all the positions but particularly for the last grooves, for which the numerical result’s deviation to the experimental measurements was less than 10%. In general, the numerical simulation tended to underestimate the pressure drop for the first grooves and overestimate the calculation for the last grooves.Peer ReviewedPostprint (published version

Valorització de residus vegetals procedents de processos industrials com a biosorbents per a l'eliminació d'ions metàl•lics d'afluents aquosos

L’objectiu d’aquest projecte és la valorització de residus vegetals procedents de processos industrials, com són el pinyol d’oliva, rapa del raïm, suro, marro de cafè, etc.,com a biosorbents per a l’eliminació de diferents ions metàl·lics, crom, arsènic, plom, cadmi, coure, níquel, etc., d’afluents aquosos.Peer Reviewe

Epstein–Barr virus-mediated transformation of B cells induces global chromatin changes independent to the acquisition of proliferation

Epstein-Barr virus (EBV) infects and transforms human primary B cells inducing indefinite proliferation. To investigate the potential participation of chromatin mechanisms during the EBV-mediated transformation of resting B cells we performed an analysis of global changes in histone modifications. We observed a remarkable decrease and redistribution of heterochromatin marks including H4K20me3, H3K27me3 and H3K9me3. Loss of H4K20me3 and H3K9me3 occurred at constitutive heterochromatin repeats. For H3K27me3 and H3K9me3, comparison of ChIP-seq data revealed a decrease in these marks in thousands of genes, including clusters of HOX and ZNF genes, respectively. Moreover, DNase-seq data comparison between resting and EBV-transformed B cells revealed increased endonuclease accessibility in thousands of genomic sites. We observed that both loss of H3K27me3 and increased accessibility are associated with transcriptional activation. These changes only occurred in B cells transformed with EBV and not in those stimulated to proliferate with CD40L/IL-4, despite their similarities in the cell pathways involved and proliferation rates. In fact, B cells infected with EBNA-2 deficient EBV, which have much lower proliferation rates, displayed similar decreases for heterochromatic histone marks. Our study describes a novel phenomenon related to transformation of B cells, and highlights its independence of the pure acquisition of proliferation

Eina informàtica basada en el guiatge de l’alumne, per l’anivellament dels coneixements previs de química, de primer curs de la UPC de la titulació d’Enginyeria Industrial, mitjançant la plataforma de suport a la docència (Atenea v.4.0)

Durant aquest projecte s’ha recopilat i estructurat un material didàctic adequat perquè l’alumnat, en especial el que no hagi cursat assignatures de química abans del seu ingrés a la universitat, pugui aconseguir uns coneixements de química convenients per poder seguir eficaçment l’assignatura de Química I, corresponent a la fase selectiva de la titulació d’Enginyeria Industrial impartida a la ETSEIB. A continuació, aquest material s’ha desenvolupat i adaptat dins del recurs de la plataforma de suport docent Atenea v 4.0 la “lliçó”, que permet el guiatge de l'alumnat per la resolució de problemes, afavorint així el seu auto-aprenentatge i per tant l’anivellament dels coneixements de química dels grups de Química I, finalitat principal d’aquest projecte de millora docent. En total s’han creat 4 lliçons diferents : 1: Formulació i nomenclatura de química inorgànica. 2: Gasos i dissolucions. 3: Reaccions químiques. Igualació de reaccions. 4: Estequiometria. Cadascuna d’aquestes lliçons s’ha plantejat amb una part de teoria amb exemples resolts per mostrar-los com a models de resolució, i una altra part amb una sèrie d’exercicis proposats perquè l’alumnat pugui practicar els conceptes associats. Finalment, s’ha implementat durant el primer quadrimestre del curs 2008-09 en els 7 grups (aproximadament 500 alumnes) de l’assignatura mencionada.Peer Reviewe

Prevalence and seasonality of viral respiratory infections in a temperate climate region : A 24-year study (1997-2020)

Background: Few long-term reports have been published on the epidemiology of respiratory viruses despite their frequent involvement in extremely common infections. The aim here was to determine the frequency and distribution of respiratory viruses in a temperate climate area (Barcelona, Spain) throughout a 24-year period. Methods: We collected data on all respiratory viruses detected from 1997 to 2020 in our institution. Clinical specimens were analyzed mainly by conventional techniques, and molecular techniques were also used. Results: Of the 59,579 specimens analyzed, 21,382 (35.9%) were positive for at least one virus. The number of positive samples during cold months was significantly higher than in warm months. Respiratory virus infections were detected in patients of all ages, above all in children under 3 years of age, who were most frequently infected with the respiratory syncytial virus, whereas Influenza A virus predominated in the other groups, especially in adults. A clear demographic and seasonal pattern was established for some viruses. Circulation of other respiratory viruses during the FLUAV H1N1pdm09 and SARS-CoV-2 pandemics was observed. Conclusions: This long-term study provides new knowledge about the prevalence of respiratory viruses in a Mediterranean region. Throughout the study period, the frequency of some viruses remained constant, whereas others varied with the year. A clear demographic and seasonal pattern was established for some viruses. Patients suffering from severe respiratory infections should be examined for a range of respiratory viruses regardless of gender, age, or season

Working landscapes need at least 20% native habitat

International agreements aim to conserve 17% of Earth's land area by 2020 but include no area‐based conservation targets within the working landscapes that support human needs through farming, ranching, and forestry. Through a review of country‐level legislation, we found that just 38% of countries have minimum area requirements for conserving native habitats within working landscapes. We argue for increasing native habitats to at least 20% of working landscape area where it is below this minimum. Such target has benefits for food security, nature's contributions to people, and the connectivity and effectiveness of protected area networks in biomes in which protected areas are underrepresented. We also argue for maintaining native habitat at higher levels where it currently exceeds the 20% minimum, and performed a literature review that shows that even more than 50% native habitat restoration is needed in particular landscapes. The post‐2020 Global Biodiversity Framework is an opportune moment to include a minimum habitat restoration target for working landscapes that contributes to, but does not compete with, initiatives for expanding protected areas, the UN Decade on Ecosystem Restoration (2021–2030) and the UN Sustainable Development Goals