325 research outputs found
Review of magnetic nanostructures grown by focused electron beam induced deposition (FEBID)
We review the current status of the use of focused electron beam induced deposition (FEBID) for the growth of magnetic nanostructures. This technique relies on the local dissociation of a precursor gas by means of an electron beam. The most promising results have been obtained using the Co₂(CO)₈ precursor, where the Co content in the grown nanodeposited material can be tailored up to more than 95%. Functional behaviour of these Co nanodeposits has been observed in applications such as arrays of magnetic dots for information storage and catalytic growth, magnetic tips for scanning probe microscopes, nano-Hall sensors for bead detection, nano-actuated magnetomechanical systems and nanowires for domain-wall manipulation. The review also covers interesting results observed in Fe-based and alloyed nanodeposits. Advantages and disadvantages of FEBID for the growth of magnetic nanostructures are discussed in the article as well as possible future directions in this field.Financial support by several projects is acknowledged: MAT2014-51982-C2-1-R, MAT2014-51982-C2-2-R and MAT2015-69725-REDT from MINECO (including FEDER funding), CELINA COST Action CM1301, Aragón Regional Government through project E26, FP7 Marie Curie Fellowship 3DMAGNANOW, EPSRC Early Career Fellowship EP/M008517/1 and Winton Fellowship
On the Commutative Equivalence of Context-Free Languages
The problem of the commutative equivalence of context-free and regular languages is studied. In particular conditions ensuring that a context-free language of exponential growth is commutatively equivalent with a regular language are investigated
The aggregation of cytochrome C may be linked to its flexibility during refolding
Large-scale expression of biopharmaceutical proteins in cellular hosts results in production of large insoluble mass aggregates. In order to generate functional product, these aggregates require further processing through refolding with denaturant, a process in itself that can result in aggregation. Using a model folding protein, cytochrome C, we show how an increase in final denaturant concentration decreases the propensity of the protein to aggregate during refolding. Using polarised fluorescence anisotropy, we show how reduced levels of aggregation can be achieved by increasing the period of time the protein remains flexible during refolding, mediated through dilution ratios. This highlights the relationship between the flexibility of a protein and its propensity to aggregate. We attribute this behaviour to the preferential urea-residue interaction, over self-association between molecules
An FPTAS for Stochastic Unbounded Min-Knapsack Problem
In this paper, we study the stochastic unbounded min-knapsack problem
(). The ordinary unbounded min-knapsack problem states that:
There are types of items, and there is an infinite number of items of each
type. The items of the same type have the same cost and weight. We want to
choose a set of items such that the total weight is at least and the total
cost is minimized. The \prob~generalizes the ordinary unbounded min-knapsack
problem to the stochastic setting, where the weight of each item is a random
variable following a known distribution and the items of the same type follow
the same weight distribution. In \prob, different types of items may have
different cost and weight distributions. In this paper, we provide an FPTAS for
, i.e., the approximate value our algorithm computes is at
most times the optimum, and our algorithm runs in
time.Comment: 24 page
Decaying Dark Matter in the Supersymmetric Standard Model with Freeze-in and Seesaw mechanims
Inspired by the decaying dark matter (DM) which can explain cosmic ray
anomalies naturally, we consider the supersymmetric Standard Model with three
right-handed neutrinos (RHNs) and R-parity, and introduce a TeV-scale DM sector
with two fields \phi_{1,2} and a discrete symmetry. The DM sector only
interacts with the RHNs via a very heavy field exchange and then we can explain
the cosmic ray anomalies. With the second right-handed neutrino N_2 dominant
seesaw mechanism at the low scale around 10^4 GeV, we show that \phi_{1,2} can
obtain the vacuum expectation values around the TeV scale, and then the
lightest state from \phi_{1,2} is the decay DM with lifetime around \sim
10^{26}s. In particular, the DM very long lifetime is related to the tiny
neutrino masses, and the dominant DM decay channels to \mu and \tau are related
to the approximate \mu-\tau symmetry. Furthermore, the correct DM relic density
can be obtained via the freeze-in mechanism, the small-scale problem for power
spectrum can be solved due to the decays of the R-parity odd meta-stable states
in the DM sector, and the baryon asymmetry can be generated via the soft
leptogensis.Comment: 24 pages,3 figure
Axion-mediated dark matter and Higgs diphoton signal
We consider axion-mediated dark matter models motivated by Fermi gamma ray
line at 130 GeV, where anomaly interactions of an axion-like scalar mediate a
singlet Dirac fermion dark matter (DM) to electroweak gauge bosons. In these
models, extra vector-like leptons generate anomaly interactions for the axion
and can also couple to the SM Higgs boson to modify the Higgs-to-diphoton rate.
We can distinguish models by the branching fraction of the DM annihilation into
a photon pair, favoring the model with a triplet fermion. From the condition
that the lighter charged extra lepton must be heavier than dark matter for no
tree-level DM annihilations, we also show that the ratio of Higgs-to-diphoton
rate to the SM value is constrained by vacuum stability to 1.4(1.5) for the
cutoff scale of 10(1) TeV.Comment: 29 pages, 6 figures, references adde
Nanoscale chemical and structural study of Co-based FEBID structures by STEM-EELS and HRTEM
Nanolithography techniques in a scanning electron microscope/focused ion beam are very attractive tools for a number of synthetic processes, including the fabrication of ferromagnetic nano-objects, with potential applications in magnetic storage or magnetic sensing. One of the most versatile techniques is the focused electron beam induced deposition, an efficient method for the production of magnetic structures highly resolved at the nanometric scale. In this work, this method has been applied to the controlled growth of magnetic nanostructures using Co₂(CO)₈. The chemical and structural properties of these deposits have been studied by electron energy loss spectroscopy and high-resolution transmission electron microscopy at the nanometric scale. The obtained results allow us to correlate the chemical and structural properties with the functionality of these magnetic nanostructures.The authors acknowledge the Spanish Ministry of Science for the financial support through Project No. MAT2008-06567-C02, including FEDER funding, the Aragon Regional Government Grant No. E26. RFP acknowledges F. De la Peña, K. March, and R. Arenal for the scientific discussions. RFP also acknowledges the Spanish Ministry of Science for the funding through a postdoctoral contract
Decaying Dark Matter in Supersymmetric Model and Cosmic-Ray Observations
We study cosmic-rays in decaying dark matter scenario, assuming that the dark
matter is the lightest superparticle and it decays through a R-parity violating
operator. We calculate the fluxes of cosmic-rays from the decay of the dark
matter and those from the standard astrophysical phenomena in the same
propagation model using the GALPROP package. We reevaluate the preferred
parameters characterizing standard astrophysical cosmic-ray sources with taking
account of the effects of dark matter decay. We show that, if energetic leptons
are produced by the decay of the dark matter, the fluxes of cosmic-ray positron
and electron can be in good agreements with both PAMELA and Fermi-LAT data in
wide parameter region. It is also discussed that, in the case where sizable
number of hadrons are also produced by the decay of the dark matter, the mass
of the dark matter is constrained to be less than 200-300 GeV in order to avoid
the overproduction of anti-proton. We also show that the cosmic gamma-ray flux
can be consistent with the results of Fermi-LAT observation if the mass of the
dark matter is smaller than nearly 4 TeV.Comment: 24 pages, 5 figure
SILAC-based proteomic quantification of chemoattractant-induced cytoskeleton dynamics on a second to minute timescale
Cytoskeletal dynamics during cell behaviours ranging from endocytosis and exocytosis to cell division and movement is controlled by a complex network of signalling pathways, the full details of which are as yet unresolved. Here we show that SILAC-based proteomic methods can be used to characterize the rapid chemoattractant-induced dynamic changes in the actin–myosin cytoskeleton and regulatory elements on a proteome-wide scale with a second to minute timescale resolution. This approach provides novel insights in the ensemble kinetics of key cytoskeletal constituents and association of known and novel identified binding proteins. We validate the proteomic data by detailed microscopy-based analysis of in vivo translocation dynamics for key signalling factors. This rapid large-scale proteomic approach may be applied to other situations where highly dynamic changes in complex cellular compartments are expected to play a key role
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