230 research outputs found
Two Scalable Approaches for Burned-Area Mapping Using U-Net and Landsat Imagery
Monitoring wildfires is an essential step in minimizing their impact on the
planet, understanding the many negative environmental, economic, and social
consequences. Recent advances in remote sensing technology combined with the
increasing application of artificial intelligence methods have improved
real-time, high-resolution fire monitoring. This study explores two proposed
approaches based on the U-Net model for automating and optimizing the
burned-area mapping process. Denoted 128 and AllSizes (AS), they are trained on
datasets with a different class balance by cropping input images to different
sizes. They are then applied to Landsat imagery and time-series data from two
fire-prone regions in Chile. The results obtained after enhancement of model
performance by hyperparameter optimization demonstrate the effectiveness of
both approaches. Tests based on 195 representative images of the study area
show that increasing dataset balance using the AS model yields better
performance. More specifically, AS exhibited a Dice Coefficient (DC) of 0.93,
an Omission Error (OE) of 0.086, and a Commission Error (CE) of 0.045, while
the 128 model achieved a DC of 0.86, an OE of 0.12, and a CE of 0.12. These
findings should provide a basis for further development of scalable automatic
burned-area mapping tools
Biological interactions and simulated climate change modulates the ecophysiological performance of Colobanthus quitensis in the Antarctic ecosystem
Most climate and environmental change models predict significant increases in temperature and precipitation by the end of the 21st Century, for which the current functional output of certain symbioses may also be altered. In this context we address the following questions: 1) How the expected changes in abiotic factors (temperature, and water) differentially affect the ecophysiological performance of the plant Colobanthus quitensis? and 2) Will this environmental change indirectly affect C. quitensis photochemical performance and biomass accumulation by modifying its association with fungal endophytes? Plants of C. quitensis from King George Island in the South Shetland archipelago (62°09′ S), and Lagotellerie Island in the Antarctic Peninsula (65°53′ S) were put under simulated abiotic conditions in growth chambers following predictive models of global climate change (GCC). The indirect effect of GCC on the interaction between C. quitensis and fungal endophytes was assessed in a field experiment carried out in the Antarctica, in which we eliminated endophytes under contemporary conditions and applied experimental watering to simulate increased precipitation input. We measured four proxies of plant performance. First, we found that warming (+W) significantly increased plant performance, however its effect tended to be less than watering (+W) and combined warming and watering (+T°+W). Second, the presence of fungal endophytes improved plant performance, and its effect was significantly decreased under experimental watering. Our results indicate that both biotic and abiotic factors affect ecophysiological performance, and the directions of these influences will change with climate change. Our findings provide valuable information that will help to predict future population spread and evolution through using ecological niche models under different climatic scenarios
Aligned Grains and Scattered Light Found in Gaps of Planet-Forming Disk
Polarized (sub)millimeter emission from dust grains in circumstellar disks
was initially thought to be due to grains aligned with the magnetic field.
However, higher resolution multi-wavelength observations along with improved
models found that this polarization is dominated by self-scattering at shorter
wavelengths (e.g., 870 m) and by grains aligned with something other than
magnetic fields at longer wavelengths (e.g., 3 mm). Nevertheless, the
polarization signal is expected to depend on the underlying substructure, and
observations hitherto have been unable to resolve polarization in multiple
rings and gaps. HL Tau, a protoplanetary disk located 147.3 0.5 pc away,
is the brightest Class I or Class II disk at millimeter/submillimeter
wavelengths. Here we show deep, high-resolution 870 m polarization
observations of HL Tau, resolving polarization in both the rings and gaps. We
find that the gaps have polarization angles with a significant azimuthal
component and a higher polarization fraction than the rings. Our models show
that the disk polarization is due to both scattering and emission from aligned
effectively prolate grains. The intrinsic polarization of aligned dust grains
is likely over 10%, which is much higher than what was expected in low
resolution observations (~1%). Asymmetries and dust features are revealed in
the polarization observations that are not seen in non-polarimetric
observations.Comment: Published in Natur
Southern Ocean mesocyclones and polar lows from manually tracked satellite mosaics
A new reference dataset of mesocyclone activity over the Southern Ocean has been developed from the manual analysis of high resolution infrared satellite mosaics for winter 2004. Of the total 1735 mesocyclones which were identified and analyzed about three quarters were classified as being ‘polar lows’ (i.e. intense systems; see Rasmussen and Turner 2003). The dataset includes mesocyclone track, size, associated cloud vortex type and background synoptic conditions. Maxima in track density were observed over the Bellingshausen Sea and around East Antarctica and are highly correlated with cyclogenesis regions. A comparison against QuikSCAT and reanalyses wind characteristics shows that the reanalyses, while capturing mesocyclone events, tend to considerably underestimate their wind speed (by up to 10 ms-1). This mesocyclone dataset is available as a reference for further analysis of mesocyclones and for the evaluation and development of cyclone-tracking algorithms
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy
Glial proliferation and activation are associated with disease progression in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar dementia. In this study, we describe a unique platform to address the question of cell autonomy in transactive response DNA-binding protein (TDP-43) proteinopathies. We generated functional astroglia from human induced pluripotent stem cells carrying an ALS-causing TDP-43 mutation and show that mutant astrocytes exhibit increased levels of TDP-43, subcellular mislocalization of TDP-43, and decreased cell survival. We then performed coculture experiments to evaluate the effects of M337V astrocytes on the survival of wild-type and M337V TDP-43 motor neurons, showing that mutant TDP-43 astrocytes do not adversely affect survival of cocultured neurons. These observations reveal a significant and previously unrecognized glial cell-autonomous pathological phenotype associated with a pathogenic mutation in TDP-43 and show that TDP-43 proteinopathies do not display an astrocyte non-cell-autonomous component in cell culture, as previously described for SOD1 ALS. This study highlights the utility of induced pluripotent stem cell-based in vitro disease models to investigate mechanisms of disease in ALS and other TDP-43 proteinopathies
Workshop Report: Container Based Analysis Environments for Research Data Access and Computing
Report of the first workshop on Container Based Analysis Environments for Research Data Access and Computing supported by the National Data Service and Data Exploration Lab and held at the National Center for Supercomputing Applications (NCSA) at the University of Illinois at Urbana-Champaign
Longitudinal Metabolite Changes in Progressive Multiple Sclerosis: A Study of 3 Potential Neuroprotective Treatments
BACKGROUND: 1 H-magnetic resonance spectroscopy (1 H-MRS) may provide a direct index for the testing of medicines for neuroprotection and drug mechanisms in multiple sclerosis (MS) through measures of total N-acetyl-aspartate (tNAA), total creatine (tCr), myo-inositol (mIns), total-choline (tCho), and glutamate + glutamine (Glx). Neurometabolites may be associated with clinical disability with evidence that baseline neuroaxonal integrity is associated with upper limb function and processing speed in secondary progressive MS (SPMS). PURPOSE: To assess the effect on neurometabolites from three candidate drugs after 96-weeks as seen by 1 H-MRS and their association with clinical disability in SPMS. STUDY-TYPE: Longitudinal. POPULATION: 108 participants with SPMS randomized to receive neuroprotective drugs amiloride [mean age 55.4 (SD 7.4), 61% female], fluoxetine [55.6 (6.6), 71%], riluzole [54.6 (6.3), 68%], or placebo [54.8 (7.9), 67%]. FIELD STRENGTH/SEQUENCE: 3-Tesla. Chemical-shift-imaging 2D-point-resolved-spectroscopy (PRESS), 3DT1. ASSESSMENT: Brain metabolites in normal appearing white matter (NAWM) and gray matter (GM), brain volume, lesion load, nine-hole peg test (9HPT), and paced auditory serial addition test were measured at baseline and at 96-weeks. STATISTICAL TESTS: Paired t-test was used to analyze metabolite changes in the placebo arm over 96-weeks. Metabolite differences between treatment arms and placebo; and associations between baseline metabolites and upper limb function/information processing speed at 96-weeks assessed using multiple linear regression models. P-value<0.05 was considered statistically significant. RESULTS: In the placebo arm, tCho increased in GM (mean difference = -0.32 IU) but decreased in NAWM (mean difference = 0.13 IU). Compared to placebo, in the fluoxetine arm, mIns/tCr was lower (β = -0.21); in the riluzole arm, GM Glx (β = -0.25) and Glx/tCr (β = -0.29) were reduced. Baseline tNAA(β = 0.22) and tNAA/tCr (β = 0.23) in NAWM were associated with 9HPT scores at 96-weeks. DATA CONCLUSION: 1 H-MRS demonstrated altered membrane turnover over 96-weeks in the placebo group. It also distinguished changes in neuro-metabolites related to gliosis and glutaminergic transmission, due to fluoxetine and riluzole, respectively. Data show tNAA is a potential marker for upper limb function. LEVEL OF EVIDENCE: 1 TECHNICAL EFFICACY: Stage 4
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