Lipid droplet detection by the cavity perturbation method

There are currently no point-of-care diagnosis strategies available to indicate the presence of neoplasmic growth. This research aims to develop a novel diagnostic strategy based on detecting TAG accumulation in cells. This element of the research is a preliminary experiment to prove the concept of detecting TAG lipid droplets in YEPD media. It was found that a change in mono-unsaturated concentration can be detected by the frequency shift in a resonant cavity. The dielectric constant of TAG vegetable oils was calculated at 2.34-2.39. It was also found that concentrations of lipid droplet can be differentiated up to 5% (v/v)

An Intermediate Luminosity Transient in NGC300: The Eruption of a Dust-Enshrouded Massive Star

[abridged] We present multi-epoch high-resolution optical spectroscopy, UV/radio/X-ray imaging, and archival Hubble and Spitzer observations of an intermediate luminosity optical transient recently discovered in the nearby galaxy NGC300. We find that the transient (NGC300 OT2008-1) has a peak absolute magnitude of M_bol~-11.8 mag, intermediate between novae and supernovae, and similar to the recent events M85 OT2006-1 and SN2008S. Our high-resolution spectra, the first for this event, are dominated by intermediate velocity (~200-1000 km/s) hydrogen Balmer lines and CaII emission and absorption lines that point to a complex circumstellar environment, reminiscent of the yellow hypergiant IRC+10420. In particular, we detect broad CaII H&K absorption with an asymmetric red wing extending to ~1000 km/s, indicative of gas infall onto a massive and relatively compact star (blue supergiant or Wolf-Rayet star); an extended red supergiant progenitor is unlikely. The origin of the inflowing gas may be a previous ejection from the progenitor or the wind of a massive binary companion. The low luminosity, intermediate velocities, and overall similarity to a known eruptive star indicate that the event did not result in a complete disruption of the progenitor. We identify the progenitor in archival Spitzer observations, with deep upper limits from Hubble data. The spectral energy distribution points to a dust-enshrouded star with a luminosity of about 6x10^4 L_sun, indicative of a ~10-20 M_sun progenitor (or binary system). This conclusion is in good agreement with our interpretation of the outburst and circumstellar properties. The lack of significant extinction in the transient spectrum indicates that the dust surrounding the progenitor was cleared by the outburst.Comment: Submitted to ApJ; emulateapj style; 39 pages; 26 figure

Effects of Sampling on Statistics of Large Scale Structure

The effects of sampling are investigated on measurements of counts-in-cells in three-dimensional magnitude limited galaxy surveys, with emphasis on moments of the underlying smooth galaxy density field convolved with a spherical window. A new estimator is proposed for measuring the k-th order moment < rho^k >: the weighted factorial moment F_k[w], corrected for the effects of the varying selection function. The cosmic error on the measurement of F_k[w] is computed via the the formalism of Szapudi & Colombi (1996), which is generalized to include selection effects. The integral equation for finding the minimum variance weight is solved numerically, and an intuitive analytical approximation is derived. The resulting estimator is more accurate than the traditional method of counts-in-cells in volume limited samples, which discards useful information. As a practical example we consider the case of the future Sloan Digital Sky Survey. Optimal (sparse) sampling strategies for designing magnitude limited redshift surveys are investigated as well. It is found that the optimal strategy depends greatly on the statistics and scales considered. Finally we consider the issue of designing the geometry of a catalog, when it covers only a small fraction of the sky.Comment: 24 pages, 9 figures, Latex (MN format), accepted for publication in MNRA

The Star Blended with the MOA-2008-BLG-310 Source Is Not the Exoplanet Host Star

High resolution Hubble Space Telescope (HST) image analysis of the MOA-2008-BLG-310 microlens system indicates that the excess flux at the location of the source found in the discovery paper cannot primarily be due to the lens star because it does not match the lens-source relative proper motion, $\mu_{\rm rel}$, predicted by the microlens models. This excess flux is most likely to be due to an unrelated star that happens to be located in close proximity to the source star. Two epochs of HST observations indicate proper motion for this blend star that is typical of a random bulge star, but is not consistent with a companion to the source or lens stars if the flux is dominated by only one star, aside from the lens. We consider models in which the excess flux is due to a combination of an unrelated star and the lens star, and this yields 95\% confidence level upper limit on the lens star brightness of $I_L > 22.44$ and $V_L >23.62$. A Bayesian analysis using a standard Galactic model and these magnitude limits yields a host star mass $M_h = 0.21 ^{+0.21}_{-0.09}~ M_\odot$, a planet mass of $m_p = 23.4 ^{+23.9}_{-9.9}~M_\oplus$ at a projected separation of $a_\perp = 1.12^{+0.16}_{-0.17},$AU. This result illustrates excess flux in a high resolution image of a microlens-source system need not be due to the lens. It is important to check that the lens-source relative proper motion is consistent with the microlensing prediction. The high resolution image analysis techniques developed in this paper can be used to verify the WFIRST exoplanet microlensing survey mass measurements.Comment: Submitted to AJ on March 18, 201

A Search for Stellar Obscuration Events due to Dark Clouds

The recent detections of a large population of faint submillimetre sources, an excess halo gamma-ray background, and the extreme scattering events observed for extragalactic radio sources have been explained as being due to baryonic dark matter in the form of small, dark, gas clouds. In this paper we present the results of a search for the transient stellar obscurations such clouds are expected to cause. We examine the Macho project light curves of 48 x 10^6 stars toward the Galactic bulge, LMC and SMC for the presence of dark cloud extinction events. We find no evidence for the existence of a population of dark gas clouds with Av > 0.2 and masses between ~ 10^-4 and 10^-2 M_solar in the Galactic disk or halo. However, it is possible that such dark cloud populations could exist if they are clustered in regions away from the observed lines of sight.Comment: 13 pages, 9 figures, submitted to Ap

The Application of Ultrasonics in Non-Destructive Testing: A Review of Some of the Research at University College London

This paper presents a review of some of the research projects at University College London which use ultrasonic waves in non-destructive testing. The projects covered include a low-frequency scanning acoustic microscope, a new dark-field acoustic microscope, an update on finite difference model studies of wave propagation and scattering, developments in mode-conversion techniques for defect characterisation, a new high-resolution acoustic field sampling probe and a resume of the work on Zn0 transducers

Computing CMB Anisotropy in Compact Hyperbolic Spaces

The measurements of CMB anisotropy have opened up a window for probing the global topology of the universe on length scales comparable to and beyond the Hubble radius. For compact topologies, the two main effects on the CMB are: (1) the breaking of statistical isotropy in characteristic patterns determined by the photon geodesic structure of the manifold and (2) an infrared cutoff in the power spectrum of perturbations imposed by the finite spatial extent. We present a completely general scheme using the regularized method of images for calculating CMB anisotropy in models with nontrivial topology, and apply it to the computationally challenging compact hyperbolic topologies. This new technique eliminates the need for the difficult task of spatial eigenmode decomposition on these spaces. We estimate a Bayesian probability for a selection of models by confronting the theoretical pixel-pixel temperature correlation function with the COBE-DMR data. Our results demonstrate that strong constraints on compactness arise: if the universe is small compared to the `horizon' size, correlations appear in the maps that are irreconcilable with the observations. If the universe is of comparable size, the likelihood function is very dependent upon orientation of the manifold wrt the sky. While most orientations may be strongly ruled out, it sometimes happens that for a specific orientation the predicted correlation patterns are preferred over the conventional infinite models.Comment: 15 pages, LaTeX (IOP style included), 3 color figures (GIF) in separate files. Minor revision to match the version accepted in Class. Quantum Grav.: Proc. of Topology and Cosmology, Cleveland, 1997. The paper can be also downloaded from http://www.cita.utoronto.ca/~pogosyan/cwru_proc.ps.g