THE POSTULATES OF THE ORGANIZATION OF THE GAME ACTIVITY A. S. MAKARENKO IN THE MODERN CAREER GUIDANCE GAME «PROFESSIONS OF THE FUTURE»

В статье рассматриваются базовые постулаты организации игровой деятельности А. С. Макаренко применительно к современной профориентационной игре «Профессии будущего». Воспитание будущего деятеля начинается в игре, каков ребенок в игре, таков он будет и в работе. Важно, с кем он играет и во что играет. Игрушка тогда хороша, когда ребенок не играет, а действует. Виды игрушек: готовая, полуготовая, игра-материал. Важно комбинировать игрушки. Педагог не может не играть, не может быть педагога, который не умел бы игратьThe article discusses the basic tenets of the organization, gaming activities of A. S. Makarenko in relation to modern career guidance game "Professions of the Future": education of the future the doer begins in the game: what is the child in the game, so will he be in the work, it is important: with whom he plays and what he plays with, the toy is then good when the child is not plays and acts. types of toys: ready, semi-ready, game material. It is important to combine toys. teacher can not play

Ultrasound therapy of diabetes mellitus type 2

We studied the possibility of low-frequency UST in the correction of carbohydrate metabolism by assessing levels of fasting glucose and Cpeptide, as well as the content of the contrinsuline hormones (cortisol, samatotropin) in groups of diabetic patients.Ultrasonic treatment was carried out at 44 kHz and amplitude of oscillations 2 microns using the therapeutic device MIT-11 on theprojection area of the pancreas stable technique, 5 times per week, exposure to the session for 3 minutes. As the contact material used liquid paraffin.To enhance the effect further impacted on the segmental zone Th7-Th12 labile technique for 2 min. for each area to the left and right. The treatmentcourse consisted of 8-10 sessions. Patients were followed for 12 months. Ultrasonic treatment was carried out against lowering drug therapy, 91patients aged 18-78 years, including type 1 diabetes was observed in 23 individuals (control group), and type 2 - 68 people. First identified diabeteswas diagnosed in 47 patients, the remaining 44 suffered from more than 5 years. Before and after treatment were studied basal levels of C-peptide,cortisol and growth hormone (GH) in serum of venous blood radio immunoassay, we determined the glycemic profile and blood sugar levels in dailyurine.Analysis of results showed that 82% surveyed, under the influence of treatment was recorded reduction of hyperglycemia with newlydiagnosed diabetes type 1 diabetes and type 2, as well as a long ill patients. Blood glucose levels prior to treatment during the day ranged from 10-15mmol / l after the treatment - 6.10 mg / dL.The resulting dynamics parameters after UST during observation showed an improvement insulinoproductive function of the pancreasunder the influence of ultrasound exposure, which contributed to a more rapid onset of diabetes compensation and reduce the dose glucose-loweringdrugs.UST is combined with many kinds of physiotherapy effects: electrotherapy, massage, balneotherapy, laser-and SWT-therapy and otheroptions for therapy with electromagnetic waves, enhancing their effect. This kind of treatment so far has not found wide application in the treatment ofdiabetes and its complications, however, is a promising method of physiotherapy treatment, given its mechanism of action and different ways ofapplication

Ultrasound therapy in medical rehabilitation post-stroke patients

The paper presents recommendations for the use of physical exercises and massage in the treatment and rehabilitation of patients withmuscular torticollis. Recommendations are intended for surgeons, doctors and exercise instructors with higher and secondary education, massagetherapists and paediatricians hospitals and clinics

Effects of platelets on extracellular traps of neutrophils in patients with systemic lupus erythematosus

Platelets are central participants in hemostasis, and also contribute to the host inflammatory and immune responses. Platelets are known to have a direct effect on the formation of neutrophil extracellular traps. Moreover, the patients with systemic lupus erythematosus exhibit multidirectional disturbances in the functional activity of platelets and neutrophils. Changes in inflammatory and thrombotic events can be considered predictors for adverse clinical course in systemic pathology. The aim of present study was to evaluate the possible role of platelets in maintaining increased netosis in patients with systemic lupus erythematosus. Blood platelets and white blood cells from 29 patients with systemic lupus erythematosus (SLE) were subject to the study. We have registered the in vitro effects of platelets upon formation of extracellular traps by autologous neutrophils under the conditions of co-cultivation for 30 minutes (vital NETosis) and 150 minutes (suicidal NETosis), as well as the relationships between the platelet counts, their activity and the number of NETs observed. It was found that the severity and direction of the platelets effect upon NETosis in vitro cultures depends on the degree of activity of disease: in the 1st degree of SLE, the effect of platelets did not differ from healthy individuals, i.e., intact platelets suppress NETosis (p = 0.002), whereas ADP-induced patelets did not exert any effect); at the 2nd degree of activity, both intact and activated platelets increase NETotic activity (p = 0.03 and p = 0.04 for intact and activated platelets, respectively). In the patients with 3rd degree of the disease activity, platelets did not affect formation of NETs. Hyperactivation of platelets was detected in SLE patients, mostly pronounced in the cases with 2nd degree of activity. However, we have not revealed any significant relationships between the count of platelets, their functional activity (according to results of ADP-test aggregation), and the indexes of NETosis. At the same time, the counts of neutrophil extracellular traps in bloodstream depended on the concentration of C-reactive protein (r = 0.58; p = 0.02), the titer of autoantibodies (anti-SS-A and anti-SS-B) (r = 0.66; p = 0.04 and r = 0.76; p = 0.02, respectively), rheumatoid factor (r = 0.73; p = 0.007) and circulating immune complexes (r = 0.68; p = 0.02). The obtained results indicate that the platelet/neutrophil interactions are not the leading cause for increased NETs numbers in SLE, compared to significantly higher effects of soluble autoagressive factors

Game technologies as a means of increasing the educational motivation of university students

Game technologies allow bringing the educational process as close as possible to professional activities, activating the cognitive interest of students in the study of professional disciplines. The purpose of the article is to analyze the experience of implementing gaming technologies in the preparation of students of higher educational institutions to increase their motivation for learning. Game technologies are a set of methods and techniques for organizing the educational process in the form of various games that stimulate cognitive activity. They allow you to simulate a real workflow and consolidate theoretical material. Motivation is defined as a set of internal motivations that explain the student’s behavior, orientation and activity in the educational process. Motivation acts as a continuous choice and decision-making based on weighing behavioral alternatives. The article presents a study of the impact of gaming technology on changing students' motivation. As a tool for the study of motivation, we used Dubovitskaya methodology for the diagnosis of motivation. The study reflects the impact of gaming technology on changing student motivation. The implementation of gaming technologies in the training of students of a higher educational institution helps to increase the motivation of students to study professional disciplines, the formation of professional competence

Evaluation of strawberry cultivars as sources of high winter hardiness and productivity

Background. The realization of high productivity potential in strawberry plants significantly depends on their adaptability to soil and climate conditions of their cultivation. Winter hardiness is the most important trait in the central part of Russia. With this in view, the purpose of this study was to identify sources of high winter hardiness combined with high productivity and yield potential among the studied cultivars.Materials and methods. The research was carried out at the primary variety testing site of the All-Russian Research Institute of Fruit Crop Breeding (VNIISPK), Orel Province, in accordance with the published program and methodology of fruit, berry and nut variety studies. The testing covered 23 domestic and foreign strawberry cultivars. An Espec PSL-2KPH climate chamber (Japan) and a Polair refrigerator cabinet (Russia) were used for artificial freezing.Results. Winter hardiness of strawberry cultivars was assessed under artificial freezing conditions. Cvs. ‘Korona’, ‘Tsaritsa’, ‘Solovushka’ and ‘Sara’ were the most winter-hardy cultivars. The study of the cultivars in the field made it possible to identify the most productive and large-fruited ones: ‘Alba’, ‘Azia’, ‘Bereginya’ and ‘Tsaritsa’. Cv. ‘Tsaritsa’ combines high winter hardiness and high yield productivity and yield potential, being a valuable source of these traits in breeding practice. According to a set of indicators ‘Tsaritsa’ is promising for large-scale cultivation in the Central Black Earth Region of Russia

Structural-energy states of water and aqueous solutions under external influence

The surface state of alkaline-earth metals and magnesium oxides obtained by means of commercial and laboratory ways has been studied in this paper. A complex of methods has been used for identification, determination of a phase composition and morphology of the samples. The high basic character of surface centres has been shown with the help of pH-metry and adsorption of indicators methods. Acid-basic parameters (pHt, pHiis, etc.) can be used for the estimation of a general acid-basic state of metal oxides samples surface and for the supposition about different nature and strength of acid-basic centres as well as for the initial control in the process of acid basic properties of solid oxides surface properties evaluation

Особенности прохождения фенологических фаз интродуцированных сортов земляники садовой в условиях Орловской области

Relevance. The study of the timing and duration of individual phases of the development of strawberry cultivars of different ecological and geographical origin in these climatic conditions is of great practical importance. The purpose of the study was the determination of the timing of the main phenophases of introduced strawberry cultivars in the Orel region, the compliance of the phenorhythms of the studied cultivars with climatic conditions, as well as the ranking of the cultivars by the terms of flowering and maturation.Methods and materials. The article presents the results of phenological observations for the period 2016-2019. 34 strawberry cultivars of domestic and foreign selection were studied. The research was carried out at the VNIISPK site of primary variety study.Results. Based on long - term observations, on the time of entry into the flowering and fruiting phase, the cultivars were ranked into early, medium and late-maturing. The influence of effective temperatures on the onset of phenophases was analyzed. The sum of effective temperatures necessary for the beginning of flowering of strawberry cultivars of different maturation periods in the conditions of the Orel region was determined. For the onset of strawberry flowering, it takes from126.68 to 260.37°effective temperatures. Early cultivars need the sum of effective temperatures of 126.68-197.55°, cultivars of middle maturation need 146.31-225.44°, late cultivars - 159.93-260.37 depending on the year of study. Fruiting occurs at the sum of effective temperatures in early cultivars from 351.73°C to 465.43°C, in middle-maturing cultivars from 390.96 to 535.44°C, in late-maturing cultivars from 450°C to 649°C.Актуальность. Изучение сроков наступления и продолжительности отдельных фаз развития сортов земляники садовой разного эколого-географического происхождения в данных климатических условиях имеет большое практическое значение.Целью исследования являлось определение сроков прохождения основных фенофаз интродуцированных сортов земляники в условиях Орловской области, соответствие феноритмов изучаемых сортов климатическим условиям, а также ранжирование сортов по срокам цветения и созревания.Материал и методы. В статье представлены результаты фенологических наблюдений за период 2016-2019 годов. Изучено 34 сорта земляники садовой отечественной и зарубежной селекции. Исследования выполнены на участке первичного сортоизучения ФГБНУ ВНИИСПК.Результаты. На основании многолетних наблюдений по времени вступления в фазу цветения и плодоношения сорта ранжированы на ранние, средне- и позднеспелые. Проанализировано влияние эффективных температур на сроки наступления фенофаз. Определена сумма эффективных температур, необходимая для начала цветения сортов земляники разных сроков созревания в условиях Орловской области. Для наступления цветения земляники требуется от 126,68 до 260,37° эффективных температур: ранним сортам – 126,68-197,55°, сренеспелым –146,31-225,44°, поздним – 159,93-260,37 в зависимости от года исследования. Плодоношение наступает при сумме эффективных температур у ранних сортов – от 351,73°С до 465,43°С, у среднеспелых – от 390,96 до 535,44°С, у позднеспелых – от 450°С, до 649°С

Cholera Vibrios non-O1/non-O139 Isolated in the Process of Epidemiological Monitoring over Rostov-on-Don Water Basins and Drain Sewage System within the Period of 2009–2011

Studied have been biological properties of cholera vibrios non-O1/non-O139 circulating in the Rostov-on-Don surface waters and drain sewage system within the period of 2009–2011. Overwhelming majority of the isolates have been classified as typical ones in terms of their phenotype. However 90 strains (21 %) out of total 280 have been identified as atypical ones against agglu­tina­bility in the slide-agglutination and full-scale agglutination reaction to diagnostic cholera sera. Put forward are recommendations on performance of the differentiation between V. cholerae non-O1/non-O139 and V. cholerae O1/O139. Specified are predominant sero­groups of the strains which turned to be unchanged within the stated period (O16, O53, O76, and O67). Revealed is the strain genotype variability and low probability of virulence manifestations. Demonstrated is the futility of the blind gene- and serological typing of aquatic strains